Although almost all cases of thyrotoxicosis can be controlled with antithyroid drugs, the rate of permanent remission is disappointing. Shortly after the introduction of these drugs, some investigators reported that over 80 per cent of patients remained ...

AN increased risk of leukemia has been reported in patients with multiple myeloma and Hodgkin's disease treated with alkylating agents.^{1 2 3} Although this risk may be directly related to the therapy, longer survival in these diseases may permit expression ...

SOMATOSTATIN, a potent inhibitor of insulin and glucagon secretion, has been suggested as a therapeutic agent in diabetes mellitus on the basis of its hypoglycemic effects in normal and diabetic man.^{1 2 3 4} Studies using prolonged infusions of ...

The relationship of renin-angiotensin system activity to the pathogenesis of hypertension remains controversial. Recently, pharmacologic technics have been used to assess the role of angiotensin.^{1 , 6} One agent, SQ 20881 (pyr-trp-pro-arg-pro-gln-ile-pro-...

Despite the dangers of generalizing about the way most physicians engaged in primary practice think or behave in the United States and the United Kingdom some differences are evident. Moreover, these differences often reflect the pressures, regulatory, ...

(Third of Three Parts)

Integrated Regulation of Ventilation

In the previous sections we have analyzed two of the major components of the respiratory control system: the sensors, and the central controller. In this section we shall discuss the relations ...

Nature (genes) will not thrive (mature and reproduce) without nurture (diet). Biologic systems require an input of energy, elements and molecules to sustain function, hyperplasia, hypertrophy and renewal. Differentiation of species has been accompanied by ...

ON a recent visit to the United States one of my tasks was to speak about health care in Britain today at a symposium on the wider topic of world health care. While preparing my presentation, I found myself recalling the serious problems that have ...

Presentation of Case

A 60-year-old woman was admitted to the hospital because of fever and lymphadenopathy.

She was well until one month earlier, when a mild sore throat developed, with fever, enlarged cervical lymph nodes, malaise and fatigue. A throat ...

During the past three decades many physicians have treated thyrotoxic patients with antithyroid drugs until toxicosis was controlled, and then discontinued therapy. Thyroid "experts" have usually counseled that this was an erroneous approach, and that ...

Chemotherapy has become increasingly important in the treatment of neoplastic disease in the past two decades. Appreciable numbers of patients with advanced Hodgkin's disease, choriocarcinoma, acute lymphocytic leukemia, testicular carcinoma and ...

I use the word "ecumenical" in its broadest sense to mean a uniting of the forces in medicine and science that could deliver a convincing political clout. I have seemed to oppose government tirelessly, and tiresomely, and I know many do not approve. But ...

Computed tomography (CT) is a sophisticated diagnostic x-ray procedure that was developed in Great Britain and introduced in the United States in 1973. The need for CT scanners, particularly for newer devices capable of scanning the entire body, remains ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Bone-marrow failure in the presence of adequate hematinic substances is a rare finding in pregnancy, and both conditions are coincidental in the majority of the patients.¹ In the present case, a pure erythroid aplasia appeared during the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A closer analysis of the data in the article by Esler and his co-workers (N Engl J Med 296:405, 1977) indicates that eight out of 16 patients in the group with high plasma renin activity (PRA) had only isolated systolic hypertension with ...

To the Editor: Propranolol is being used increasingly in both medical and neurologic practice. We should like to call attention to a possible neuromuscular complication associated with this drug. In a patient seen recently at our institution, we noted ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A tuberculin reaction may be "boosted" from no reaction (or only 3 to 9 mm) on an initial test to a reaction that is considered "positive" (10 mm or more of induration) when a person is retested at a later time. It appears that such a ...

To the Editor: Regarding the article by Shurin et al. (N Engl J Med 296:412, 1977) and the editorial by Paradise (N Engl J Med 296:445, 1977) a word of caution is necessary because of the tendency of many clinicians to overuse tympanometry in the ...

No extract is available for articles shorter than 400 words.

To the Editor: In the haste to set up CAT scanners in hospitals and offices many have forgotten that these units were designed to serven patients. Because of inadequate planning by manufacturers, radiologists and hospital administration too many CAT ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

COURSE ON CLINICAL PHARMACOLOGY AND ANESTHETIC PRACTICE

A program entitled "Pharmacology for Anesthesia" will be held at the Del Monte Hyatt House in Monterey, California, September 23–25. The fee is $125 for physicians and $75 for nurses, residents and ...

An angry physician telephoned me recently. Just back from a hard day with his patients, he said, he had read — I'd say, misread — a newspaper article I had written about health care. Though he wasn't mentioned in the article, he wanted to know, as he more ...