Peripheral blood lymphocytes cytotoxic in vitro to tumor cells have been described in patients with a variety of tumors, including breast, bladder, melanoma, gastrointestinal, neuroblastoma and osteogenic sarcoma.^{1 2 3 4 5 6} The clinical usefulness of in ...

Two key enzymes, hypoxanthine guanine phosphoribosyltransferase (HGPRT: E.C. 2.4.2.8) and adenine phosphoribosyltransferase (APRT: E.C. 2.4.2.7), catalyze the reaction of phosphoribosylpyrophosphate with the respective base to form the corresponding ...

The classic uremic breath odor is familiar to clinicians who come into contact with patients in chronic renal failure. This odor has been variously called "fishy," "ammoniacal," and "fetid." Schreiner and Maher,¹ in their review, described it as ...

Generalized pruritus is a common, frequently severe symptom of uremia that affects up to 85 per cent of patients on chronic hemodialysis.¹ For many years sun exposure has been known to relieve the pruritus associated with several unrelated dermatoses, and ...

(Second of Three Parts)

Central Respiratory Controller

The respiratory controller, located within the CNS, is composed of two functionally and anatomically separate elements. Voluntary respiration is governed primarily by the cortex, and automatic ...

Many patients with membranoproliferative glomerulonephritis and partial lipodystrophy have low levels of serum C3.^{1 2 3 4} Serum of these patients incubated with normal human serum may produce alternative-pathway-mediated cleavage of C3.^{5 6 7} The C3 ...

IN 1974, we reported¹ on 16 patients with refractory hematologic neoplasia who were treated with high-dose cyclophosphamide, supralethal total-body irradiation, bone-marrow transplantation from a normal genetically identical twin and, most often, "...

IN mammals, a fifth to a third of the large volume of plasma that enters the kidney is driven through the capillary walls of the glomerulus to form glomerular filtrate. Micropuncture technics have made it possible to sample this glomerular filtrate and ...

Presentation of Case

A 47-year-old woman was admitted to the hospital because of dyspnea.

Twenty-eight years previously she began to have attacks of wheezing that were relieved with bronchodilator medication. Six weeks before entry she saw a physician ...

The article by Yu et al. (p. 121), demonstrating the presence of one population of lymphocytes cytotoxic for autologous tumor cells and another inhibiting this cytotoxicity in patients with osteogenic sarcoma, is representative of the explosion of ...

Henry Blackburn advanced the idea that physicians tend to take either an academic or pragmatic view of atherosclerosis.¹ The academic view asserts that attempts to change individual living habits are hopeless — that research should be directed toward ...

The familiar path led quickly into the beech woods and up beside the brook that tumbles noisily over smooth, brown granite in a series of chutes and cascades. The warmth of the sun, filtering through the branches, was tempered by the cool dampness of the ...

To the Editor: The two recent articles on granulocyte transfusion in the March 31 issue of the Journal and the accompanying editorial raise several questions, some of which Dr. Boggs addressed. I fear the articles will be lightly read, the editorial ...

No extract is available for articles shorter than 400 words.

To the Editor: Recently we observed a 2940-g female baby with neonatal myasthenia gravis who was delivered at full term from a 30-year-old primiparous Japanese woman who had had generalized myasthenia gravis for two years. Several hours after birth the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

CHILDREN'S HOSPITAL BURN SYMPOSIUM

The third annual Children's Hospital Burn Symposium will be held at the Children's Hospital, Denver, Colorado on Friday, September 9.

Further information may be obtained from Dr. William Carl Bailey, Burn Team, Children'...