Measurement of serum prostatic acid phosphatase levels is widely used to detect prostatic cancer since the level of this enzyme usually rises during the course of the disease.^{1 2 3 4 5} Often, the level of prostatic acid phosphatase (E.C. 3.1.3.2) ...

Cardiovascular disease is one of the most frequent complications in patients under hemodialysis and after renal transplantation.^{1 2 3 4 5} Several studies have shown the frequency of hyperlipoproteinemia as a major risk factor of coronary heart disease in ...

IN the years after his Croonian lectures, Sir Archibald Garrod expanded his concepts of inborn errors of metabolism to include inborn predispositions to metabolic disorders.^{1 2 3} He suggested that inborn predispositions, like inborn errors, resulted from ...

(Second of Three Parts)

Mouse Erythroleukemia Cells

Our emphasis on the biochemical aspects of globin-gene expression and mRNA production parallels the focus of much experimental work, but should not obscure the fact that erythroid maturation represents a ...

BY the middle of the 20th century, Pneumocystis carinii pneumonitis had not been recognized in North America. Yet within the past two decades the prevalence has increased to the point that several hundred cases occur annually in the United States. The ...

Intercellular transfer of information is frequently accomplished through receptors that recognize specific chemical signals such as hormones or neurotransmitters and respond to their presence by initiating a chain of events leading to an appropriate ...

Thrombotic thrombocytopenic purpura, the acute form of which is usually fatal, is characterized clinically by thrombocytopenia, microangiopathic hemolytic anemia, fluctuating neurologic signs and renal dysfunction, and pathologically by diffuse thrombotic ...

Presentation of Case

A 41-year-old physician was admitted to the hospital because of pneumonia.

He was well until 2 1/2 weeks earlier, when vague myalgias developed, with rise of the temperature to nearly 39°C. He took acetaminophen, with symptomatic ...

Acid phosphatase was the first "tumor marker" that could be measured in the blood, and 40 years have passed since an elevation of the serum acid phosphatase was first noted in patients with prostatic cancer.¹ The prostatic acinar epithelium elaborates ...

...our genes cannot make bricks without straw. The individual differences which men and women display are partly due to the fact that they receive different genes from their parents and partly due to the fact that the same genes live in different houses.*

Thrombotic thrombocytopenic purpura (TTP) has been recognized as a clinical entity for more than 50 years.¹ The classic histologic lesions of this remarkable disease are "microthrombi" consisting mainly of platelets and fibrin, which can be found in the ...

Dr. Frank N. Allan, internationally known physician in the field of diabetes, died on July 12, 1977. Born in Proton, Ontario, December 26, 1899, he graduated in medicine from the University of Toronto in 1922 and, in 1928, received the higher-thesis ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Contrary to the opinion expressed by Dr. Lewis,¹ the impact of health-services research can be very substantial under the right conditions. His query was directed at establishing a link between health-services research and "innovations" — ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The authors accurately describe this book as "concerned with the anatomical and physiological features that are to be found in the high altitude native...and with the changes of acclimatization that occur in the sea level subject who ascends for a short ...

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Radiology and Radiation

Clinical ...

CONFERENCE ON ENDOSCOPY

The Medical College of Wisconsin will present the sixth annual Endoscopy Conference entitled "A Comprehensive Approach to Endoscopy" at the Pfister Hotel and Tower in Milwaukee, February 1–4. The deadline for registration is ...

If your fiscal lifelines run to Washington, it is useful to be in harmony with the agencies that send you money. What is also useful is a public expression of support from the President, the reason being that your friends in the bureaucracy are not ...