The incidence of gallbladder disease in children and adolescents is low.¹ The only study of biliary lipid composition in children suggests that a low molar percentage of cholesterol is one of the factors responsible for this observation.² However, as in ...

Platelets obtained from diabetic subjects have a lower threshold for aggregation and a greater per cent aggregation in response to ADP, epinephrine and collagen than those of normal subjects.^{1 2 3 4 5 6} When platelets aggregate and undergo the release ...

A MAJOR obstacle to the general application of bone-marrow transplantation is that the majority of the patients afflicted with the lethal disorders for which this approach is indicated will lack a histocompatible sibling donor.^{1 , 2} The probability that ...

(First of Three Parts)

The process of erythroid-cell differentiation represents one of the most striking examples of biologic specialization known in nature. Erythropoiesis begins with an undifferentiated stem cell that, within seven to 10 days, gives ...

Schistosomiasis, one of the more important worm infestations of mankind, is widely distributed over three continents, affecting more than 200 million people, and is often associated with considerable morbidity. Unlike almost all other parasitic ...

Clinicians who treat the elderly are concerned with a degenerative process that affects everyone — a progressive deterioration that proceeds at different rates in different patients, that influences the presentation of acute illnesses and their response ...

Presentation of Case

A 76-year-old man was admitted to the hospital because of renal failure.

He was well until four months earlier, when he experienced transient bilateral paresthesia with questionable dysarthria. Two months before admission he suddenly ...

Platelets change shape, aggregate and release their granule contents in response to collagen, thrombin, ADP, short-lived compounds formed from arachidonic acid, epinephrine and other stimuli. Platelet aggregation and release play a part in the development ...

IT has been said that experiments in medical education always tend to revert, after initial enthusiasm has waned, to established patterns. The record, however, supports no such view. Perusal in detail of curriculum content and sequence, especially in the ...

Determination-of-need laws now exist in 33 states and the District of Columbia. The National Health Planning and Resources Development Act of 1974 (PL 93–641) mandates that such statutes must be adopted in every state by 1980. These laws have the laudable ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The alpha-fetoprotein assay is a useful tool in the antenatal detection of neural-tube defects.¹ Several other nonspecific abnormalities, including Turner's syndrome,² omphalocele,³ esophageal atresia,⁴ congenital nephrotic syndrome,⁵ ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We have previously described in the Journal a 46-year-old woman with a history of diabetes for eight years and a pancreatic islet-cell tumor containing a large quantity of immunoreactive somatostatin.¹ Two other patients with somatostatin-...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: I recently had the opportunity to obtain and evaluate extensively a large cache of Laetrile products (ampuls and tablets) produced by Cyto Pharma of Mexico. Cyto Pharma is the major distributor of Laetrile, labeled "Amygdalina," in Mexico ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.