Treatment goals for chronic stable angina include: prolonged survival, decreased cardiovascular morbidity and improved quality of life. Of these three goals, survival is the most unequivocal and definitive to evaluate, provided adequate follow-up ...

The problem of whether or not to perform an elective lymph-node dissection in cases with clinically uninvolved regional lymph nodes is one of the most discussed questions in the treatment of malignant melanoma. Such a procedure is considered necessary in ...

Methotraexate, an effective agent in treatment of leukemia, choriocarcinoma and other tumors, is one of the most versatile antineoplastic agents because its toxicity in high-dose regimens can be prevented by the reduced folate, leucovorin (5-...

Vitiligo, a disease characterized by the loss of melanin pigment that follows the destruction of melanocytes, has been associated with hyperthyroidism, hypothyroidism, hypoparathyroidism, pernicious anemia, diabetes mellitus, mucocutaneous candidiasis and ...

The Harvard Primary Care Program was established to provide postgraduate education in primary-care internal medicine, with quality patient care by residents at participating practices and opportunities for research in primary care. The Program includes ...

A GENERATION of research on the diet-heart question has ended in disarray. The official line since 1950 for management of the epidemic of coronary heart disease has been a dietary treatment. Foundations, scientists and the media, both lay and scientific, ...

Total Hip Replacement

Total hip replacement, pioneered by Professor Sir John Charnley and introduced in 1962 with the materials currently in use, began the modern era of major joint reconstruction. Few surgical advances have so revolutionized a field. The ...

Presentation of Case

A 36-year-old woman was admitted to the hospital because of a mass in the parotid gland.

She was well until one year previously, when a hard lump was felt at the left mandibular angle. She was evaluated at a hospital in Georgia, where ...

The surgical treatment of coronary-artery disease began early in this century when surgical sympathectomy was reported as a successful treatment for angina pectoris. Since then a variety of procedures have been tried, all of which were greeted with ...

Malignant melanoma, a visible cutaneous lesion, innocuous and readily curable at inception, but unsightly, painful and usually fatal at advanced stages, continues to attract medical interest far out of proportion to its incidence, approximately 1 per cent ...

Recombinant DNA is becoming the Farrah Fawcett-Majors of scientific issues of the day. It is impossible to get through a week's reading of newspapers and magazines (let alone scientific publications) without encountering yet another insider's view of this ...

To the Editor: Laskowski et al. (N Engl J Med 297:101, 1977) described eight patients receiving porcine aortic valves from Hancock Laboratory contaminated with Mycobacterium chelonei. Only one patient sustained possible ill effects to this date.

A 55-...

To the Editor: It has been amply demonstrated that the initial pleocytosis in viral meningitis may be predominantly polymorphonuclear before shifting to the characteristic mononuclear response.¹ We have been unable, however, to find reports documenting ...

To the Editor: The correspondence by Yokoyama et al. (N Engl J Med 296:282, 1977) is interesting in showing that the distribution of hepatitis B surface antigen (HBsAg) in the Yonaguni Island of Okinawa is similar to that in Southeast Asia but does not ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Initial reports by Gluck on the lecithin/sphingomyelin (L/S) ratio and by Clements on the foam stability test (FST) showed that their tests correlated well with fetal lung maturity.^{1 , 2} Since then, the FST has generally been considered a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Phencyclidine (PCP) was developed as a short-acting analgesic for general anesthesia but is no longer used medicinally in human beings because of its postoperative side effects.¹ Phencyclidine, however, has found its way onto the streets ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: At a recent conference the director of the National Institute of Aging reported that Cornell University is to have a chair of geriatric medicine. He also reported that it was the first such chair in the United States. The news, gratifying ...

To the Editor: An interesting phenomenon occurred recently at one of our public hospitals that I believe should be shared with other physicians using the IVAC 811 thermometer system.

The non-air-conditioned hospital wards were recently subjected to three ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Psychiatry

Piagetian Theory and ...

PROGRAM SCHEDULE AT McGILL UNIVERSITY

The Centre for Continuing Medical Education at McGill University has made available a listing of its 1977–1978 programs.

Further information may be obtained from the Centre for Continuing Medical Education, McGill ...

The National Cancer Act was due for its second three-year renewal this year. But with Congress burdened by the legislative requests of a new administration, the Cancer Act, along with a lot of other healthrelated legislation, was given a one-year ...