Islet-cell tumors, like many other endocrine tumors, are recognized during life by clinical syndromes related to hypersecretion of one or more hormones.^{1 , 2} With a variety of technics, some subtle differences between the secretions of the benign and ...

Since December, 1975, five independent studies have presented evidence of a potentially causative association between exogenous estrogen therapy and the development of endometrial carcinoma.^{1 2 3 4 5} Shanklin⁶ and others have suggested that these reports ...

Ankylosing spondylitis, although sometimes disabling, is generally thought not to be a life-threatening disease. Despite recurrence of symptoms and progression of ankylosis in many patients, potentially serious complications, such as may be associated ...

IN some patients with renal hyperchloremic acidosis, persisting hyperkalemia is characteristic.^{1 2 3 4 5 6 7 8 9 10 11} In contrast to the renal potassium-wasting characteristic of patients with distal (Type 1) and proximal (Type 2) renal tubular acidosis,^...

(Second of Two Parts)

Reactions of Non-Erythroid Cells with Cold Agglutinins

Recently, it has been shown that cold agglutinins react with Ii antigens on many types of normal and malignant cells in addition to red cells. In the presence of complement, the ...

The relation between cigarette smoking and serious cardiopulmonary disease has been convincingly established^{1 , 2} and has impelled a search for effective methods of helping smokers to break the habit. Nevertheless, there are few effective methods.^{3 , 4} ...

Since patients with asthma have great difficulty in emptying their lungs, it has generally been assumed that large positive intrathoracic pressures are generated in this condition. On the other hand, the clinical observation that patients with acute ...

The air passages of the lung are not rigid tubes; they can reduce their caliber in response to chemicals, such as sulfur dioxide, drugs, such as histamine, and antigenic agents, such as ragweed pollen. The effects of these substances may be direct and ...

Presentation of Case

A 38-year-old woman was admitted to the hospital because of a pericardial effusion.

Nine years earlier she was told that she had asymptomatic aortic stenosis and slight cardiac enlargement. She remained free of symptoms until three ...

In this issue of the Journal Kahn et al. describe the use of radioimmunoassays for alpha chain, beta chain and intact human chorionic gonadotropin (hCG) to distinguish malignant from benign pancreatic islet--cell neoplasms. To put their observations in ...

Kaplan's Letter to the Editor in this issue of the Journal advises that a contract providing long-term hospital treatment of tuberculosis has been terminated, leaving only one such facility in Massachusetts; this situation echoes a trend occurring ...

No extract is available for articles shorter than 400 words.

In the last 17 years, the emergence of a new fertility-control technology, based primarily on the oral contraceptive, has led to increasingly effective regulation of reproduction. The principal characteristics of this technology are that the new methods ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Egdahl and Walsh, in their Sounding Board article on "Industry-Sponsored Health Programs: Basis for a new hybrid prepaid plan" (N Engl J Med 296:1350–1353, 1977), describe the basis for a new hybrid prepaid comprehensive health-care plan ...

SYMPOSIUM ON NEW FRONTIERS IN HEPATITIS

The 14th annual Clinical Day of the Jewish General Hospital of Montreal entitled "New Frontiers in Hepatitis" will be held on Wednesday, October 19.

Further information may be obtained from Medical Education, Jewish ...