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February 3, 1977  Vol. 296 No. 5

Original Articles
237-241

The ventilatory response to acute hypoxia has been found to be subnormal in native residents of high altitudes. In these subjects, the blunted response has been attributed to prolonged residence in an oxygen-poor environment.1 2 3 4 A similar phenomenon ...

241-244

Infection with hepatitis B virus is common in patients undergoing chronic hemodialysis and in patients who have received kidney transplants,1 , 2 but whether the infection affects the prognosis of these patients is uncertain.3 , 4 To gain information on ...

245-248

Congenital generalized lipodystrophy is a rare disease, characterized by an overall paucity of fat in subcutaneous adipose tissue. A typical feature of the disease is a reduced glucose tolerance in the presence of high circulating insulin levels, the ...

248-250

    There are many reports of familial aggregation of Hodgkin's disease; yet the magnitude of familial risk is unknown.1 2 3 Recent findings imply interpersonal transmission of an etiologic agent of Hodgkin's disease.4 5 6 If transmission occurs, relatives of ...

    Special Article
    251-256

    It is surprising that extensive survey of physician's prescriptions has become a reality only recently. As a succinct, formal document of the physicianpatient encounter, the prescription has no peer. Depending upon the thoroughness of the monitoring ...

    Medical Intelligence
    257-260

    Drug-induced tardive dyskinesia represents a major side effect limiting long-term use of antipsychotic drugs and responds poorly to treatment. The drugs most frequently associated with this syndrome are the phenothiazines and haloperidol. Spontaneous ...

    260-261

    Children may be exposed through various mechanisms to toxins of industrial origin. Contamination of the home environment by soiled work clothing is an important mechanism of such exposure and has been associated with the development of mesothelioma,1 ...

    261-262

    Pruritus is one of the most disturbing and poorly understood symptoms in patients on chronic hemodialysis,1 2 3 4 its reported prevalence varying from 15 to 86 per cent. Except for a few case reports of a dramatic response to subtotal parathyroidectomy,1 ,...

    263-264

      Propranolol is useful in the management of the cardiovascular and neuromuscular problems occurring in hyperthyroid patients.1 , 2 Propranolol has been used as the sole drug in preparation of patients for thyroidectomy,3 , 4 in the treatment of pregnant ...

      264-265

      The internal organization of most American hospitals is an uneasy union of medical-care delivery by physicians and the administration of a medical-care facility by the hospital's governing board. For most patients, the key functionary is the attending ...

      Physiology in Medicine
      266-271

      Opiates have had therapeutic relevance since antiquity and are still among the most widely used drugs in medical practice. The euphoric and calming actions of opiates fostered their clinical use as sedatives, "antianxiety agents," hypnotics and ...

      Case Records of the Massachusetts General Hospital
      271-276

      Presentation of Case

      A 59-year-old man entered the hospital because of cranial-nerve palsies.

      Twenty-one years earlier he had an episode of severe vertigo and nausea that persisted for three days. During the next five years mild vertigo recurred on three ...

      Editorials
      277-278

        ON casual inspection the study by Oseid et al., "Decreased Binding of Insulin to Its Receptor in Patients with Congenital Generalized Lipodystrophy," appears to concern a single unusual metabolic disorder. In fact, this work adds directly to emerging ...

        279-280

        After three decades of unprecedented advances in basic biomedical knowledge the American taxpayer, who has for the most part footed the bill, is calling increasingly for a payoff on his investment. Many of his elected representatives, such as Senator ...

        Sounding Board
        280-281

        The public debate devoted to the medical malpractice situation and NHI has left little media time or space for discussion of another issue that will ultimately have a greater effect on the type of medical care available in this country.

        I suggest that the ...

        Correspondence
        282

        To the Editor: In Japan, about 0.5 to 2.0 per cent of subjects investigated are HBs-antigen positive, and the dominant subtype is r — consistent with the interesting geographic subtype distribution.1 However, in Southeast Asia 2.8 to 6.2 per cent of the ...

        282

        No extract is available for articles shorter than 400 words.

        282-283

        To the Editor: In certain special cases, a gastrotomy has proved to be a useful therapeutic approach for the removal of large quantities of drugs that tend to form concretions in the stomach. The application of that therapeutic modality to the patient of ...

        283

        No extract is available for articles shorter than 400 words.

        283

        No extract is available for articles shorter than 400 words.

        284

        No extract is available for articles shorter than 400 words.

        284-285

        No extract is available for articles shorter than 400 words.

        285-286

        No extract is available for articles shorter than 400 words.

        286

        No extract is available for articles shorter than 400 words.

        286-287

        No extract is available for articles shorter than 400 words.

        287

        No extract is available for articles shorter than 400 words.

        287-288

        No extract is available for articles shorter than 400 words.

        288

        No extract is available for articles shorter than 400 words.

        288-289

        No extract is available for articles shorter than 400 words.

        289

        No extract is available for articles shorter than 400 words.

        Book Review
        289-290

        This book, the primary and, to date, principal report of the Task Force on Consumer Health Education, does more to define the concept of health education and to relate it to realities of medical health care than any other comparable contemporary document. ...

        Notices
        290

        ERYTHROPOIETIN PREPARATION AVAILABLE

        The Division of Blood Diseases and Resources of the National Heart, Lung, and Blood Institute announces the availability of human urinary erythropoietin for research purposes to qualified investigators. Erythropoietin ...

        Medicine and Public Affairs
        291-292

        Being concerned with high policy matters, my professional inquiries into medical affairs normally partake more of the long-distance observational technics of astronomy than of on-the-ground collection of data.

        The rationale for this is that it is easier ...

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