Graves's disease has usually been defined in the past two decades as a multisystem disorder consisting of one or more of three pathognomonic entities: hyperthyroidism due to diffuse goiter; infiltrative ophthalmopathy; and infiltrative dermopathy ("...

Ethanol and diazepam are commonly ingested sedatives. A recent survey conducted by the National Institute on Drug Abuse (Drug Abuse Warning Network) disclosed that in emergency-room visits resulting from ingestion of two or more drugs, the most frequently ...

Anorexia nervosa is a disorder occurring primarily in young women whose clinical features include obsessive dieting in the pursuit of thinness, as well as amenorrhea, lanugo hair and physical hyper-activity. Recent studies from our laboratory have shown ...

Chatterjee et al. reported that the presence of hepatitis B antigen in renal-graft recipients did not prejudice graft and patient survivals up to two years after transplantation.¹ A similar conclusion was reached by Shons et al.² It has even been recently ...

Bite-Mark Evidence

Few subjects within the domain of forensic odontology have received as much attention within recent years as bite-mark evidence. In such situations the bite-mark pattern may be looked upon as somewhat comparable to an ante-mortem dental ...

Until recently, the need to understand the details of cardiac hemodynamics was confined to the small group of cardiologists who performed, or were required to interpret the results of, cardiac catheterization. This situation has all changed, however, ...

Over 20 million prescriptions are written annually for tricyclic antidepressants.¹ The cardiotoxicity of overdosage is well documented,^{2 3 4 5} but little is known about cardiac effects of therapeutic plasma concentrations.^{4 , 6 , 7} The toxic effects of ...

The sympathetic nervous system has been implicated in the pathogenesis of hypertension because of its role in controlling blood pressure and because many drugs that have been found useful in the treatment of essential hypertension either block ...

Gilles de la Tourette syndrome is a neurologic disorder in which there are both motor and behavioral abnormalities, approximately 75 per cent of the patients are male and the onset of the disease is usually between two and 14 years of age.^{1 , 2} Recently, ...

Three years ago the medical profession in Britain set up a committee "to review the present methods of ensuring the maintenance of standards of continuing competence to practise and of the clinical care of patients, and to make recommendations." The ...

Presentation of Case

A 71-year-old woman was admitted to the hospital because of an abnormal x-ray film of the chest.

She was well until 16 months previously, when she complained of vague postprandial epigastric distress. An upper gastrointestinal series ...

The infiltrative ophthalmopathy of Graves's disease may precede, accompany or follow the onset of hyperthyroidism. Proptosis, soft-tissue involvement and ophthalmoplegia, occurring in an obviously thyrotoxic patient, or in one with a history of ...

Pirson and his colleagues report elsewhere in this issue of the Journal that patients found to have hepatitis B surface antigen (HB_s Ag) in their circulation before or after renal transplantation have a fivefold increase in deaths (10 deaths in 61 ...

A few years ago it was established that opiates bind to the cell membrane of some of the neurons of the central nervous system. These synaptosomal opiate receptors were shown, in all the vertebrates studied, to be distributed in discrete localizations of ...

In Massachusetts, as in other states, pressures for regionalization of perinatal health services have been intensified by a number of changes in demography, patterns of care, and public and physician education. The nation's birthrate fell from 25 live ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: White patches of skin and gray hair occur in people with vitiligo because the pigment cells, melanocytes, are destroyed in skin and hair follicles. A combination of immunologic and cytotoxic mechanisms produces this loss of melanocytes. ...

To the Editor: The American Cancer Society has announced a new policy for mass screening of women under 50 years of age by mammography that is focused on women in eight "high-risk" categories.¹ Dr. Bailar and I, among other epidemiologists, have already ...

No extract is available for articles shorter than 400 words.

To the Editor: Acetaminophen in large doses is a well known cause of fulminant hepatic disease in Europe, particularly in Great Britain.¹ In 1975 there were 7000 hospital admissions for acetaminophen overdose in the United Kingdom,² with a mortality rate ...

No extract is available for articles shorter than 400 words.

To the Editor: We spent most of the afternoon of our 27th wedding anniversary in the giant dolphin tank at Marineland! That is to say, my husband, Sam, was in the tank. I was on the outside holding his clothes and my breath.

At about 1 p.m. that Saturday,...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This excellent book, which attempts to integrate the helter-skelter thinking that has both preceded and evolved from the helter-skelter attempts at solutions to important national health needs, was written both for those who are sympathetic to the ...

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, COURSES

The University of California, San Francisco, will present the following courses at the Fairmont Hotel, San Francisco: "Diagnostic Nuclear Imaging," March 5 and 6; "Diagnostic Radiology: 1977," March 7–11; ...