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June 2, 1977  Vol. 296 No. 22

Original Articles
1245-1249

    Studies of the reproductive status of men with severe chronic renal failure leading to hemodialysis have established that spermatogenesis is impaired.1 2 3 In the few patients investigated, spermatogenesis was decreased to degrees varying from a mild ...

    1250-1253

    Glucagon has been described as an essential hormone in diabetes1 , 2 and a prerequisite for the development of ketoacidosis3 and endogenous hyperglycemia.4 However, the importance of this hormone as a primary etiologic factor in the metabolic disturbance ...

    1254-1258

    Cytomegaloviruses are unquestionably the most common cause of congenital infection in man, with a rate ranging from 0.5 to 2.0 per cent of all live births.1 2 3 4 5 Yet the mode (or modes) of transmission of virus from mother to fetus remains ill defined ...

    Special Article
    1258-1264

    Most of those invited to give a lecture in the famed Shattuck series begin by expressing their gratitude, but for reasons that I hope will become evident, I shall postpone comments of that type to the end. Furthermore, unlike some of my illustrious ...

    Medical Intelligence
    1265-1267

    In 1955 Gardner and Diamond1 described four women in whom purpura, erythema, edema and painful ecchymoses developed either spontaneously or at sites of minimal trauma on the trunk and extremities. Extensive studies of standard hemtologic and coagulation ...

    1268-1269

      Sepsis in the newborn infant may be defined as a clinical syndrome characterized by systemic signs of infection and accompanied by bacteremia in the first month of life. Despite the introduction of potent antimicrobial agents, the mortality of neonatal ...

      1269-1271

      Although a few cases of renal carcinoma extending into the vena cava and right atrium have been reported,1 2 3 to our knowledge no reported cases of pheochromocytoma have behaved in a similar fashion. In a case of gross tumor extension into the vena cava ...

      1271-1273

      The treatment of vasospasm during ergotism has been difficult and unconvincing.1 2 3 A combination of hyperbaric oxygen and sympathetic blockade by means of continuous epidural anesthesia has been claimed to have some effect in limiting the ischemic ...

      1273-1274

      Medical research in this country is predominantly supported by federal grants and contracts. The great fear of investigators is that the government will exact too high a price in regulation to make this research feasible and worthwhile.

      One major source ...

      Physiology in Medicine
      1274-1278

      The brain has a major role in regulation of respiration, heart rate, blood pressure and release of hormones such as ACTH, and in the complex control of temperature and electrolyte balance. The lower centers of the brain, which regulate many of these vital ...

      Case Records of the Massachusetts General Hospital
      1279-1287

      Presentation of Case

      A 23-year-old woman was admitted to the hospital because of multiple traumatic injuries.

      She was well until the evening before admission, when she was involved in a motor-vehicle accident. She was taken to another hospital, where the ...

      Editorials
      1288-1289

      Clinically, the severity of uremia is inversely proportional to sexual desire and activity in patients with chronic renal failure. Men and women alike are affected, the deficiency being generally more obvious in men because of requirements for performance ...

      1289-1290

      Successful immunization to prevent an infectious disease is most easily accomplished when certain conditions are met: the infection and its disease are readily detected and identified, and they occur in close temporal association; the offending virus has ...

      Sounding Board
      1291-1293

      The accelerating entry of nurses, medical corpsmen and others of diverse educational and experience backgrounds into clinical areas once the exclusive domain of physicians is testing fundamental assumptions about the nature of primary care and the ...

      Massachusetts Medical Society
      1293-1294

      DEATHS

      Amiral — Hiram Hygazon Amiral, M.D., of Southboro, died on June 13. He was in his 86th year.

      Dr. Amiral received his degree from Harvard Medical School in 1916. He was a member of the Association of Life Insurance Medical Directors of America, the ...

      Correspondence
      1295

      To the Editor: Since the advent of Giemsa band analysis, a number of cytogenetic anomalies have been identified in the bone marrow of patients with chronic myelocytic leukemia. Our own series since 1973 includes 49 patients (17 female and 32 male) ...

      1295-1296

      No extract is available for articles shorter than 400 words.

      1296-1297

      No extract is available for articles shorter than 400 words.

      1297-1298

      No extract is available for articles shorter than 400 words.

      1298-1299

      To the Editor: There is strong evidence that a reovirus-like agent,1 usually referred to as rotavirus,2 is a major cause of nonbacterial gastroenteritis in infants and children in many parts of the world.3 The role of rotavirus in gastroenteritis in ...

      1299

      No extract is available for articles shorter than 400 words.

      1299-1300

      No extract is available for articles shorter than 400 words.

      1300-1301

      To the Editor: One year ago we read in the correspondence columns of the Journal descriptions of two technics that are important to those responsible for setting up and maintaining access to peripheral veins in patients — the use of saline for local ...

      1301

      No extract is available for articles shorter than 400 words.

      1301

      To the Editor: Within recent months physicians, scientists and lay persons alike have witnessed an increasingly active Food and Drug Administration whose promulgations, right or wrong, have done much to affect our daily lives. Capitalizing upon these ...

      1301-1302

      No extract is available for articles shorter than 400 words.

      1302

      No extract is available for articles shorter than 400 words.

      Book Reviews
      1302

      No extract is available for articles shorter than 400 words.

      1302-1303

      No extract is available for articles shorter than 400 words.

      1303

      The resurgence of interest in bronchial asthma is encouraging: clinical immunologists and chest physicians have joined forces to uncover the pathogenesis of a disease that is as mysterious as it was a millennium ago. One may not always agree with the ...

      1303

      No extract is available for articles shorter than 400 words.

      1303-1304

      No extract is available for articles shorter than 400 words.

      Books Received
      1304

      No extract is available for articles shorter than 400 words.

      Notices
      1304

      SEMINAR IN PEDIATRICS

      Colby College of Waterville, Maine will present a seminar on current topics in pediatrics, July 17–20.

      Further information may be obtained from Robert H. Kany, Special Programs, Colby College, Waterville, Maine 04901.

      COURSE IN BASIC ...

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