The kidney has a major role in calcium and phosphate metabolism. It not only is an important site of action of the major regulating hormones, parathyroid hormone, calcitonin and vitamin D but also takes part in their metabolism. Thus, the kidney is the ...

The terms familial erythrocytosis and familial polycythemia encompass a heterogeneous group of disorders with the common characteristic of an increased red-cell mass occurring in related persons. The most frequent cause of erythrocytosis in these families ...

Primary liver cancer is one of several tumors capable of ectopic production of hormones or hormone-like substances. Syndromes arising in this way in patients with primary liver cancer include hypoglycemia,¹ erythrocytosis,² hypercalcemia³ and precocious ...

When tests involve risk to the patient, the usefulness of information provided by the test must be balanced against the chance of harming the patient. Such judgments must often be empirical and are subject to error since probabilities are estimated and ...

Pharmacologic Interventions

A number of pharmacologic agents reduce myocardial ischemic injury in the laboratory animal, and some have been used in limited numbers of patients. The activation of the complement system via its alternate pathway, a shift ...

Radioisotopes are finding increasing use in the evaluation of both right and left ventricular function.¹ Two approaches have emerged that show promise for clinical application. Measurements of ventricular function, including ventricular ejection fraction ...

Rotor's syndrome is an inheritable disorder characterized by chronic nonhemolytic, predominantly conjugated hyperbilirubinemia without abnormal hepatic pigmentation.^{1 2 3 4} Because of clinical similarities, Rotor's syndrome has been considered to be a ...

Hypophosphatemia is now recognized with increasing frequency as a cause of several systemic disorders.^{1 2 3 4 5 6 7} Routine use of multichannel blood analysis has disclosed this condition in as many as 10 per cent of certain hospital populations.^{8 , 9} In ...

We've never been so self-conscious about our selves as we seem to be these days. The popular magazines are filled with advice on things to do with a self: how to find it, identify it, nurture it, protect it, even, for special occasions, weekends, how to ...

Presentation of Case

First admission. A 56-year-old woman was admitted to the hospital because of pneumonia.

She was well until three months previously, when a chronic nasal dryness became more severe. An x-ray film of the chest was normal except for ...

Renal osteodystrophy continues to be one of the more difficult problems that confront the clinician charged with the responsibility of managing patients with chronic renal failure. The clinical picture of decreased intestinal calcium absorption, excessive ...

Advances in medical knowledge tend to come in bursts or at least in great strides. A tiny nucleus of an idea gathers momentum and mass, like tumbleweed rolling through the desert. The sum total of what is gathered may be impure and imprecise, but ...

After Wands et al.¹ reported that some people with precirrhotic hemochromatosis have normal levels of serum ferritin it soon became evident that others had observed the phenomenon without commenting on it.^{2 , 3} It was a sad development that a test ...

Herrman Blumgart began his career under the tutelage of Henry Christian at the Peter Bent Brigham Hospital and of Francis Peabody at the Thorndike Laboratory, where he made his first contribution to cardiology. Both institutions harbored vigorous minds in ...

Drawing on two decades of experience in the United States with controlled fluoridation, Dunning¹ reported in 1965 that few public-health measures are so unequivocally effective against widespread disease. Fluoridation of community water supplies is safe, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The American College of Obstetrics and Gynecology, the Nurses Association of the College and the American College of Nurse Midwives have recognized the deficits in availability and quality of United States maternity care and the increasing ...

No extract is available for articles shorter than 400 words.

Immunobiology for the Clinician. By Hugh R.K. Barber, M.D. 310 pp., illustrated. New York: John Wiley and Sons, 1977. $19.50.

Clinical Immunobiology is the third in a series of books aimed at providing clinical immunologists with an up-to-date background ...

YAMAGIWA-YOSHIDA MEMORIAL INTERNATIONAL CANCER STUDY GRANTS

The Yamagiwa-Yoshida Memorial International Cancer Study Grants, funded by the Japan National Committee for the International Union Against Cancer with support from the Commemorative Association ...