Tetracycline hydrochloride and spectinomycin hydrochloride are the two non-penicillin antibiotics most commonly advocated in the United States for the treatment of gonorrhea, but it has been recommended that they be used as initial therapy only for ...

An increased frequency of the HLA-B8 antigen in Sjögren's syndrome has been noted.^{1 , 2} The autoimmune destruction of salivary and lacrimal glands in this disease is mediated by lymphoid cells.^{3 , 4} Regulation of the ability of the immune system to ...

Death of hospitalized patients with acute myocardial infarction has two principal causes: primary arrhythmias and failure of the cardiac pump. Death secondary to disturbances in rhythm has been markedly reduced through the use of modern monitoring ...

My assignment at this symposium is an awesome one: to consider the influence of the social environment and cultural attitudes on the genesis of psychiatric disorders. It is as though Adam had been asked to give a brief essay on the wonders of Creation. I ...

Prostaglandin Release from "Healthy," Antigen-Sensitized and Anaphylactic Lung

Investigating the chemical mediators in the pulmonary perfusates from the anaphylactic guinea pig, Piper and Vane⁵ discovered that PG's were released from the lung. Since PG's ...

Human plasma contains three vitamin B₁₂ -binding proteins known as transcobalamin I, transcobalamin II and transcobalamin III.^{1 2 3 4} The first and third belong to the immunologically related class of R-type vitamin B₁₂-binding proteins and have apparent ...

Hypercalcemia increases the effect of digitalis and its derivatives on the heart. Hypocalcemia, on the other hand, is not a recognized inhibitor of the action of digitalis, although resistance to the action of digitalis is known to occur in a variety of ...

The body's homeostasis depends on the co-ordinated activity of the nervous system and the endocrine system. Although the physiologic co-operation of these two systems has long been recognized, neurons and endocrine cells are generally regarded as ...

Presentation of Case

A 27-year-old woman was admitted to the hospital because of a pulmonary mass.

She was well until six years previously, when her first pregnancy terminated in a spontaneous abortion in the first trimester. A daughter was born two years ...

The penicillin era of the treatment of infections due to Neisseria gonorrhoeae began in 1943, when Mahoney et al.¹ demonstrated that penicillin was effective in the treatment of gonococcal urethritis in men. They gave their patients a total of 160,000 ...

PSRO's have borne out the prediction that they would be difficult to implement because of their technical, professional and political complexities. Four years and five months after the signing of PL 92–603, not one PSRO is fully operational. The reasons ...

MY colleague was steaming. "I really cannot take much more of this. This is third go-around with Ms. Brown, and she still refuses a liver biopsy. I've given her a crash course in hepatic anatomy and pathophysiology and still she is not satisfied." He ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The recent letter by Kijima et al. (N Engl J Med 296:515, 1977) cautions against the use of clofibrate in patients on chronic hemodialysis. All their patients received clofibrate in a dose of 1500 mg per day for the therapy of ...

To the Editor: A clofibrate-induced "acute muscular syndrome" has been reported in patients treated for hyperlipidemia with or without chronic renal failure.^{1 2 3 4}

In 1970 a 16-year-old boy treated for diabetes insipidus with vasopressin as a nose ...

To the Editor: In their interesting studies of enzyme replacement therapy for adenosine deaminase deficiency, Polmar et al. (N Engl J Med 295:1337, 1976) suggest that plasma adenosine may have entered the transfused red cells and may have been ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

CLINICAL CENTER STUDY OF PATIENTS WITH PITUITARY TUMORS

The co-operation of physicians is requested in the referral of patients with pituitary tumors (exclusive of those patients with acromegaly) for a study being conducted by the National Institute of ...