Transient leukopenia, selectively involving granulocytes and monocytes, occurs in all patients during the first two hours of hemodialysis with cellophane-membrane apparatus.^{1 , 2} We recently reported that such leukopenia results from pulmonary ...

The Prader-Willi syndrome of hypotonia, hypogonadism, mental retardation and obesity^{1 , 2} has as its most disabling component the obesity and related complications. Of these, diabetes and respiratory impairments have the greatest morbidity and are often ...

Recurrent urinary infections in the female, in the absence of struvite infection stones and congenital abnormalities, are almost exclusively reinfections.^{1 , 2} Although the fecal bacteria are the ultimate reservoir, bacteriuria is preceded by colonization ...

The Sulfonamides

Crystallization leading to obstructive nephropathy, allergic and hypersensitivity reactions, precipitation of hemoglobin casts secondary to drug-induced hemolysis and an intrinsic toxic effect have all been reported as secondary to ...

Treatment with Oral Hypoglycemic Agents

The main justifications for clinical use of oral hypoglycemic agents are that they are taken by mouth once or twice a day, making them more convenient and acceptable to the patient than insulin, that they are ...

Since bromocriptine is a specific dopamine receptor agonist with a prolonged action,¹ it should theoretically affect chronic portasystemic encephalopathy, in which a defect in dopaminergic neurotransmission is postulated.² The drug was successful in the ...

The California Supreme Court has decided another highly controversial medical malpractice case, finding that a physician (and a hospital) can be held liable for injuries inflicted not by the physician but by a third party. In a previous comment,¹ I ...

One of the exciting advances in endocrinology has been the discovery of a family of peptidic neurohormones in the hypothalamus that stimulate or inhibit the secretion of adenohypophysial hormones. This article briefly reviews the evolution of present ...

Presentation of Case

A five-year-old boy was admitted to the hospital because of hypospadias.

He was born of a first pregnancy, which was complicated by toxemia. Labor was induced one month prematurely; the birth weight was 2.1 kg. Perineoscrotal ...

The study in this issue of the Journal by Craddock and his colleagues provides an explanation for a problem first encountered a number of years ago: patients undergoing hemodialysis experience a transient neutropenia, in some cases accompanied by ...

The Holy Grail of Western medicine is a safe and comfortable way to lose excessive body fat. This process would, of course, require that the fat fellow be able to continue his sloth and gluttony even as the treatment works. One solution would be to find a ...

Successful treatment of urinary-tract infections in certain female patients is hindered by frequent recurrences caused by fecal bacteria. Nitrofurantoin alone and trimethoprim–sulfamethoxazole together are two recognized antimicrobial modes of therapy ...

The increasing frequency with which economists are invited to address physician forums and to contribute to medical journals suggests that some important changes are under way in American medicine. The medical leadership is apparently in search of ...

The Council met at Howard Johnson 57 Hotel, 200 Stuart Street, Boston, on Wednesday, February 9, 1977, with 254 councilors in attendance. C. Nason Burden, M.D., presided.

In relation to approving the Proceedings of the October 13, 1976, Council meeting, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Polmar et al.¹ established a cause- and-effect relation between adenosine deaminase deficiency and combined immunodeficiency by restoring immunocompetency to a seven-month-old infant with adenosine deaminase deficiency associated with ...

No extract is available for articles shorter than 400 words.

To the Editor: The Munsat editorial (N Engl J Med 296:101, 1977) on the subject of "Serotonin and Myoclonic Seizures" is a valuable contribution because it emphasizes a major new approach to therapy gradually being developed in neurology. In discussing ...

To the Editor: In 1975 we proposed that Creutzfeld-Jakob disease might be transmitted through consumption of a contaminated food source.¹ We now report the case of a 56-year-old woman of Polish ethnic origin with autopsy-proved Creutzfeldt-Jakob disease ...

No extract is available for articles shorter than 400 words.

To the Editor: The recommended subcutaneous dose (0.25 mg) can be confused with the recommended oral dose of terbutaline (2.5 mg). We should like to report a case in which this confusion occurred.

A 67-year-old woman was admitted to the hospital ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Pica is the habit of ingesting substances that lack nutritive value. Infants may eat unusual materials during the phase of oral exploration, but later in life pica usually reflects cultural preferences.^{1 , 2} Earth or clay (geophagia), ice (...

No extract is available for articles shorter than 400 words.

As though death itself were not daunting enough, the author takes on an even more formidable subject: "To ask the meaning of death is, in an indirect way, to ask the meaning of life. To ask what are the rights of the dying is to ask what are the rights of ...

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Bio and Physical Chemistry

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COURSES AT THE UNIVERSITY OF MINNESOTA

The Office of Continuing Medical Education at the University of Minnesota, Minneapolis, announces that the following programs will be presented in the coming months: "Maxillofacial Trauma," April 15–17; "Current ...