The mortality from infection in patients with compromised bone-marrow function remains high despite the use of broad-spectrum antibiotics.^{1 2 3} In 1931, the clinical implications of neutropenia as an etiologic factor in rapidly fatal bacterial infections ...

Infection is one of the major causes of morbidity and mortality in patients with granulocytopenia. The introduction of newer antibiotic drugs has improved the outlook substantially in such patients,^{1 2 3 4} although most of the drugs are less effective in ...

About 30 years ago, Ivy et al.¹ demonstrated that simultaneous administration of dextroamphetamine enhanced the analgesic effect of morphine in human volunteers' experimental pain. Ivy and others^{2 3 4} also showed that the combination did not produce many ...

It is now almost universally believed that the resources available to meet the demands for health care are limited. This fact was not, perhaps, perceived to be so a few decades ago, before health insurance became so pervasive and before medical ...

Vancomycin

Vancomycin is excreted chiefly by the kidney, with more than 80 per cent of the administered dose recovered in the urine within 24 hours.⁸⁴ Its half-life is six hours. In patients with impaired renal function, very high serum concentrations ...

As the Royal Commission inquiring into the National Health Service (NHS) proceeds with its work, many bodies have been publishing the evidence that they have submitted to the commissioners. The evidence that the British Medical Association (BMA) plans to ...

Hypertension is one of the foremost public-health problems facing this nation. Its high prevalence, the enhanced risks of mortality and morbidity from the cardiovascular and cerebrovascular diseases associated with it, and the availability of treatment ...

Presentation of Case

A 33-year-old man was admitted to the hospital because of congenital heart disease.

Intermittent cyanosis of the lips was noted in early childhood, and examination disclosed a murmur. He was seen at this hospital on three occasions ...

IN this issue of the Journal, Herzig and Alavi and their respective associates provide the most definitive evidence published to date that transfusion of neutrophils is a beneficial adjunct in the treatment of infected, neutropenic patients. As the ...

The leading edge of discovery on pain moves forward in one of its recurrent accelerations. Several phenomena have contributed to this resurgence. The first is the perennial human fascination with the sensation of pain and the natural impulse to relieve ...

The story is told that some years ago the publisher of the New York Times was asked why the Times did not print any cartoons alongside its editorials. His explanation was that in a cartoon one couldn't say, "But, on the other hand."

It is said that Harry ...

Despite the fact that neither the national Health and Nutrition Examination Survey (HANES),¹ the Framingham Studies^{2 , 3} nor the Veterans Administration Cooperative Study of Antihypertensive Therapy^{4 , 5} were designed to determine the role of hypotensive ...

The kindly, conservative gentleman who served as treasurer of the Massachusetts Medical Society for 28 years (1943 to 1971) — a longer period than that covered by any of his predecessors since the foundation of the Society in 1781 — is affectionately ...

To the Editor: The paper on "Clinical Syndrome of Variant Angina with Normal Coronary Arteriogram" by Selzer and his co-workers (N Engl J Med 295:1343, 1976) implies that the clinical picture of patients with Prinzmetal's angina can delineate those with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The special article by Mr. Norman Cousins in the issue of December 23, 1976, must surely have had a tremendous impact on many physicians as it did on me. Apart from the subject of the article, the first thing that is impressive is its ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A letter recently published in the Journal (296:119, 1977) written by an American student at a foreign medical school contains several misconceptions. He implied that the approximately 15 per cent failure rate of U.S.-trained students on ...

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Environmental and Public Health

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SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL

Seminars in Medicine of the Beth Israel Hospital will be held in the George Sherman Auditorium, Beth Israel Hospital, Boston, on the following Tuesdays at 4 p.m.

PROGRAM ON ASSURANCE AND ACCREDITATION IN ...