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March 24, 1977  Vol. 296 No. 12

Original Articles
641-646

Elevated plasma renin activity occurs in malignant and renovascular hypertension and in a subgroup of essential hypertension.1 However, the exact role of the renin-angiotensin system in maintenance or causation of most hypertensive states remain ...

647-650

Infants born before 40 weeks' gestation experience a greater fall in hemoglobin concentration than those born at term.1 , 2 Hemoglobin levels reach their lowest point at two to three months of age. This phenomenon does not appear to be associated with any ...

651-655

IN the last few years a number of patients with a severe combined immunodeficiency and lacking adenosine deaminase activity in the erythrocytes have been described.1 , 2 Adenosine deaminase catalyzes the conversion of adenosine into inosine, as part of ...

Special Article
656-663

Although the administration of educational programs in academic health centers* is much discussed, major policy questions remain unanswered. We propose some answers to these questions, but recognize that each center is different; an approach that works ...

Medical Progress
663-670

Selection of an antibiotic to use in the treatment of an infection should be based on benefittoxicity ratios, particularly in critically ill patients with marginal renal function and potentially lethal infections. Many factors intrinsic to the kidney are ...

Medical Intelligence
671-675

The most important clinical determination of ventricular function is the evaluation of the functional limits. Usually, physicians make this evaluation from their appraisal of exertional symptoms reported in a patient's history, often with considerable ...

675-676

    Anomalous origin of the left coronary artery from the pulmonary trunk is suspected with electrocardiographic evidence of myocardial infarction in patients with left ventricular failure and cardiomegaly; the diagnosis is made by selective angiography.1 , 3 ...

    Case Records of the Massachusetts General Hospital
    676-683

    Presentation of Case

    A 14-year-old boy was admitted to the hospital because of fever, lymphadenopathy and skin lesions.

    He was in excellent health until six weeks previously, when he began to experience increasing fatigue while working after school. Four ...

    Editorials
    684-685

    The relation of the activity of the renin-angiotensin system to the pathogenesis of hypertension remains controversial. In an attempt to resolve this controversy, interruption of the renin-angiotensin system by pharmacologic technics is finding increasing ...

    685-687

    The renewal rate of adult human red cells in the peripheral circulation is approximately 0.8 per cent per day. If a person is either bled or exposed to a hypoxic environment, erythropoiesis increases as measured by the uptake of 59Fe in newly formed red ...

    687-688

    In one legend a university president dies. To his surprise, he finds himself in an office identical with the one he occupied in life. Confusion about the president's fate is cleared by the sudden appearance of Mephistopheles.

    "I do not understand," the ...

    Massachusetts Medical Society
    688-690

    Published in Accordance with Chapter II, Section 2.301 of the Bylaws

    Berkshire

    Catalfumo, Frank John, 188 East Street, Pittsfield 01201. Faculty of Medicine & Surgery University of Bologna, 1967.

    Rentz, Frederick Peter, 725 North Street, Pittsfield 01201. ...

    Massachusetts Department of Public Health
    690-691

      In a search for ways to control rising medical-care costs, particularly those resulting from end-stage cardiovascular disorders, as well as to promote healthful personal behavior, a number of governments, including Canada,1 Sweden and Switzerland, have ...

      Correspondence
      691-692

      No extract is available for articles shorter than 400 words.

      692

      No extract is available for articles shorter than 400 words.

      692-693

      No extract is available for articles shorter than 400 words.

      693-694

      No extract is available for articles shorter than 400 words.

      694

      To the Editor: Prostaglandins mediate many different types of human diarrhea, especially the diarrhea associated with medullary carcinoma of the thyroid.1 Abdominal cramping and watery diarrhea with an accelerated transit of markers through the gut and ...

      694-695

      No extract is available for articles shorter than 400 words.

      695

      No extract is available for articles shorter than 400 words.

      695

      No extract is available for articles shorter than 400 words.

      Book Reviews
      696

      No extract is available for articles shorter than 400 words.

      696

      No extract is available for articles shorter than 400 words.

      696

      In the preface the author states that the purpose of this book is to provide a translation of static morphologic observations into pathophysiologic concepts that he believes to be important for the solution of clinical problems. This goal is reasonable ...

      696-697

      A quantitatively oriented policy analyst with no medical training and a cardiologist with no experience in quantitative policy analysis have not only taken the time to understand each other's language and appreciate each other's philosophy, but also ...

      697

      No extract is available for articles shorter than 400 words.

      Books Received
      697

      The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

      Communicable Diseases and ...

      Notices
      697-698

      COURSES FROM NEW YORK UNIVERSITY

      New York University Post-Graduate Medical School, New York City, will offer the following courses in the coming months: "Conception Control and Human Reproduction Seminar for Physicians," April 21 and 22; "Symposium: ...

      Medicine and Public Affairs
      699-700

      Hospital cost increases long ago joined the group of things that can't go on like this, but nevertheless do. Now comes the Carter Administration with a pledge to "cap" the process, though it admits it has "no preconceptions of the form such a system might ...

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