Leukemic reticuloendotheliosis is a disease in which an unusual mononuclear cell appears in the peripheral blood in association with the development of splenomegaly and mild to moderate pancytopenia.^{1 2 3 4 5} The disease is slow moving, and the major risk ...

Glomerulonephritis has frequently been reported as a cause of acute renal failure. Authors usually emphasize the poor prognosis of such nephropathy. No mention is made in most series of the role of infection, except for acute sore throat. In some cases, ...

Disordered function of the sinoatrial pacemaker of the heart has been recognized for over 70 years, but the suggestion that this disorder may predispose to systemic embolism is relatively recent¹ and still controversial.² In a review of all the cases ...

During the last decade, Chile has experienced a complex process of social and economic changes under different political regimes: from 1964 to 1970, under a Christian Socialist Government, from 1970 to 1973, under a Marxist Socialist regime, directed by ...

(First of Two Parts)

The essential features of tumor cells that distinguish them from their normal counterparts are their ability to proliferate in an uncontrolled fashion, invade normal tissues and metastasize to distant sites, though these behavioral ...

Congenital malformations are a common cause of illness, handicapping conditions and death. The incidence varies with the age of the person being evaluated. It is highest among spontaneous abortions, with many of the abnormalities incompatible with ...

The discovery of proinsulin by Steiner and Oyer¹ established that insulin is not synthesized as such, but as a larger precursor molecule in which the insulin A and B chains are connected by an additional peptide of 30 to 35 amino acids, depending on the ...

Chronic active type B hepatitis, a disorder caused by the hepatitis B virus, is characterized by progressive hepatocellular damage leading to cirrhosis, portal hypertension and, in some cases, to hepatocellular carcinoma.¹ Factors that allow persistent ...

The Jarisch-Herxheimer reaction may occur after the initiation of treatment for syphilis. The reaction consists of shaking chills, fever, malaise, sore throat, myalgia, headache, tachycardia and exacerbation of the inflammatory reaction at sites of ...

Presentation of Case

A 62-year-old man was admitted to the hospital because of a diagnosis of an abdominal aortic aneurysm.

He was well until several months previously, when there was the onset of weight loss in an amount of 4 kg, with vague discomfort in ...

Leukemic reticuloendotheliosis (LRE) is a term originally used by Ewald in 1923.¹ As so often happens in medicine, the original paper described a patient whose disease would probably now be classified as acute monocytic leukemia. The clinical disorder now ...

The syndrome of acute renal failure (ARF) is a confusion of multiple causes, varying from beesting to bismuth, from snakebite to sulfonamide. Almost every drug in the Pharmacopeia has been implicated in a single case report. The hard clinical fact is that ...

Some did not care for a frankly leftish account¹ of the effect on Chilean medical care when the current regime in that country ousted the Allende government three years ago. Others, predictably, will not care for the defense "written in Chile, by Chilean ...

No extract is available for articles shorter than 400 words.

The nursing-home industry in the United States is, on paper, the most closely regulated sector of the health-care system. Owing in part to the dependency of many patients¹ and their inability to exert the pressure of active consumers, in part to massive ...

No extract is available for articles shorter than 400 words.

To the Editor: The recent article, "Maternal Antibody in Group B Streptococcal Infections," by Drs. Baker and Kasper (N Engl J Med 294:753–756, 1976), demonstrates a protective maternal antibody for late-onset Group B Type III streptococcal infections. ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The article by Ingelfinger and Goldman¹ on serum digitalis concentrations is basically sound, and serves as a timely reminder that the inappropriate use of any test (and the serum digoxin concentration, in particular) is fraught with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The prognosis of neuroblastoma cannot always be forecast with accuracy, but to some extent, it is thought to be related to age at the time of diagnosis. For this and other reasons accurate diagnostic methods become critical. Twenty years ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

History

Adventures In Medical ...

On June 9, 1975, President Ford asked Congress to re-establish the Executive Office science advisory organization that his predecessor had abolished. Since Congressional sentiment already favored the restoration, there was no reason to doubt that it would ...