Autoimmune disorders involving red cells and platelets are well recognized and increasingly better understood. In striking contrast is the lack of a systematized body of knowledge on autoimmune disorders affecting leukocytes.^{1 , 2} Isolated reports on this ...

Even before the correct number of chromosomes in human cells was known, investigators had recognized that there were abnormalities of chromosome number and structure in malignant serous effusions. In 1956, Hansen-Melander et al.¹ examined the chromosomes ...

Infective endocarditis continues to be a major infectious disease.^{1 , 2} Many of its clinical and histologic features, once assumed to be a consequence of tissue invasion and injury by the causative micro-organism, are now considered to be immunologically ...

Although quality assessment is gathering institutional momentum, its value still hangs in the balance. It has the potential of improving the outcomes of health interventions and enhancing the character of priority decisions. On the other hand, poorly ...

Bile-Acid-Independent Bile Flow

Sodium transport is under investigation as a physiologic mechanism for the generation of the bile-acid-independent fraction of canalicular bile flow. The electrolyte content of bile at low bile acid output consists mostly ...

Fulminant hepatic failure is the most serious complication of viral hepatitis, the mortality of patients with Stage 4 coma being approximately 80 to 90 per cent.^{1 2 3 4} Most of the survivors recover completely, at least in part because of the remarkable ...

This study was designed to verify the importance of toxigenic Escherichia coli and other etiologic agents in diarrhea of travelers. In particular, we sought data to compare the relative importance of enteric pathogens in persons from different geographic ...

The prognosis for survival in severe aplastic anemia remains poor despite advances in management of patients with this condition over the past decade. Treatment with androgenic steroids has not been shown to be effective in pronounced bone-marrow aplasia.^...

The Royal Commission set up last year to consider "the best use and management of the financial and manpower resources of the National Health Service" is proceeding with its work. From the outset the chairman, Sir Alec Merrison, made it clear that he and ...

Presentation of Case

A 26-year-old man was admitted to the hospital because of colonic polyps.

When he was 11 years of age a bony prominence developed in the right side of the mandible. In the following year a cyst was excised from the skin of the right ...

The mechanisms involved in producing a clinical state of leukopenia with recurrent infection in man have been difficult to elucidate clearly. Certain drugs and other environmental factors can produce total marrow aplasia or selective absence of marrow ...

One of the unresolved issues dealing with the pathogenesis of infective endocarditis is whether some of the extravascular manifestations of this infection such as the glomerulitis, arthritis or skin lesions like Osler's nodes or Janeway's lesions are the ...

Fulminant viral hepatitis is a condition with an appalling mortality. Survival is only 10 to 20 per cent of those reaching the stage of deep coma, when painful stimuli cannot be appreciated. Treatment by corticosteroids, exchange blood transfusion and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Bio and Physical Chemistry

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SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL

Seminars in Medicine of the Beth Israel Hospital will be held in the George Sherman Auditorium, Beth Israel Hospital, Boston on the following Tuesdays at 4 p.m.

Date

Program

January 4

Tumor Prostaglandins ...