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December 2, 1976  Vol. 295 No. 23

Original Articles
1273-1278

In 1902, Reed1 noted that "tuberculin was given in five of [eight] cases [of Hodgkin's disease] without reaction." It was not, however, until 1932 that Parker et al.2 suggested that the frequent anergy to intradermal injection of tuberculin observed in ...

1278-1283

Over the past two decades, the systematic exploration of the renin-angiotensin system in experimental and clinical hypertensive disease has led to new concepts concerning the mechanisms that sustain normal and elevated blood pressure. The development of ...

1283-1286

Patients with an inherited deficiency of cystathionine synthase usually have elevated levels of methionine and homocystine (or homocysteine) in the plasma, and an increased urinary homocystine excretion.1 2 3 Those with this disease may have one or more ...

1287-1291

In 1961 Sipple1 called attention to a 14-fold increase in the frequency of pheochromocytoma in patients with carcinoma of the thyroid gland. Four years later, Williams2 recognized that the thyroid carcinoma was the medullary type. Subsequently, he found ...

Special Article
1292-1296

The American Surgical Association recognizes the occurrence of unforeseen and undesirable injury to patients under medical and hospital care. Patients so injured are entitled to appropriate reparation. Procedures governing such reparation should ...

Medical Intelligence
1297-1300

Acetaminophen (N-acetyl-para-amino-**■ phenol) (Fig. 1) has been used as an analgesic and antipyretic for about 80 years. The drug has become increasingly popular during the past 25 years since the recognition that the effects of another widely used para-...

1301

The Federal Food and Drug Administration (FDA) has finally achieved enactment of comprehensive legislation that will strictly regulate the growing medical-devices industry. The battle has taken over 10 years. Each year the FDA tried again to expand its ...

Physiology in Medicine
1302-1308

Of all the conflicting views on the causes of biologic aging, there is little disagreement with the axiom that, after reaching sexual maturity, individual members of a species accumulate physiologic decrements that lead to an increase in their likelihood ...

Case Records of the Massachusetts General Hospital
1309-1313

Presentation of Case

A 64-year-old man was admitted to the hospital because of hematemesis.

There was a 30-year history of hypertension treated with diuretics. Ten years before admission inferior myocardial infarction occurred, followed by anterior ...

Editorials
1314-1315

After more than a decade of investigation of lymphoid subpopulations through the use of cell markers, some recent studies are beginning to provide insights into the mysterious process known as Hodgkin's disease. Several different groups working in the ...

1315-1317

The medical profession, hospitals, and other health-care providers have borne a disproportionate share of the brunt of a combination of inadequacies, under late-twentieth-century conditions, in this country's tort-law and casualty-insurance systems. It is ...

1317-1318

Medical Journals devoted to clinical subspecialties appeal to limited interests, but no matter how telescopic their view, a goodly proportion of subspecialty-journal readers takes care of patients. Journals of this type thus influence some physicians on ...

Massachusetts Medical Society
1318

DEATHS

Burrage — Walter Swan Burrage, M.D., of Brookline, died on September 19. He was in his 82d year.

Dr. Burrage received his degree from Harvard Medical School in 1926. He served with the Navy Medical Corps during World War II. He formerly served as ...

Correspondence
1319

No extract is available for articles shorter than 400 words.

1319

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1319

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1319-1320

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1320

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1320-1321

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1321

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1322

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1322

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1322-1323

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1323

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1323-1324

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1324

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1324-1325

To the Editor: The furor related to prepublication of the "Hoover report" (N Engl J Med 295:401–405, 1976) merits further comment. Dr. Ingelfinger, in a letter to the editor of the Washington Post for August 27, wrote, in part: "Yet Mr. Mintz, by ...

1325

No extract is available for articles shorter than 400 words.

1325-1326

To the Editor: There has been much discussion about introduction of SI units, and a reaction resisting any sort of change is unfortunately developing. The September 16 issue of the Journal provides a good illustration of the present indiscriminate use of ...

1326

No extract is available for articles shorter than 400 words.

1326

No extract is available for articles shorter than 400 words.

Book Reviews
1327

The field of medical oncology is new, and at present is covered definitively by either a huge tome or small volumes directed to aspects of chemotherapy. Hence, there is a real need for a reasonably sized volume that can bridge the wide area of available ...

1327

No extract is available for articles shorter than 400 words.

1327

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1328

No extract is available for articles shorter than 400 words.

1328

This volume is a hardcover reincarnation of the November, 1975, issue of the Israel Journal of Medical Sciences. It includes 13 contributions from a generally distinguished group of authors. The strengths and weaknesses of this book are dictated by its ...

1328-1329

Here is a book, full of controversy, that should be read for fun as well as profit. Initially, the reader must surmount the obstacle suggested by the title. For physicians, the greatest day-by-day concern is centered on the many patients whose diseases ...

1329

No extract is available for articles shorter than 400 words.

1329-1330

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1330

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1330

The preface to this volume explains that it was prepared under the direction of the Committee on Pre and Postoperative Care of the American College of Surgeons, and that the chapters were written by members of the College. It is intended to provide a ...

1330

No extract is available for articles shorter than 400 words.

1331

Here is a book to read en route to the next annual meeting — an account of 1974's premier biomedical scandal. It details the shock that ensued when researcher William Summerlin created what he admits was a "terrible incident," on March 26, 1974. Dr. ...

Books Received
1331-1332

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Orthopedics

Clinical Management ...

Notices
1332

UPDATE ON CANCERS OF THE GASTROINTESTINAL SYSTEM

The University of Miami Medical Center and the Department of Radiation Therapy at Cedars of Lebanon Hospital will sponsor a program entitled "Update on Cancers of the Gastrointestinal System" at the Sonesta ...

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