Two to five per cent of children experience at least one febrile seizure in their early years. ^{1 2 3} All relevant studies agree that children who have had one or more febrile seizures are more likely to become epileptic than children who have had no ...

Variability in the bioavailability of digoxin under various clinical circumstances is becoming increasingly apparent. Interactions with other medications during gastrointestinal absorption is a case in point. Antacids have had varying effects on the ...

The nitrogen-sparing effects of isotonic amino acid solutions in postoperative patients has been a subject of intense investigation and interest in the last few years. Previous studies^{1 2 3 4 5} have focused on nitrogen balance, body weight changes and ...

Patients with the Chediak-Higashi syndrome suffer frequent and severe pyogenic infections that are secondary to abnormal function of polymorphonuclear leukocytes. The impaired bactericidal activity of the leukocytes appears related to delayed delivery of ...

(Second of Two Parts)

Macrophages

The alveolar macrophage system has been extensively studied. Alveolar macrophages are responsible for the physical removal of inhaled particles although the major clearance mechanism consists of the mucociliary transport ...

Although guanethidine has been available for treatment of hypertensive patients for more than 15 years, sufficient recent data are available so that it is appropriate to review the current use of the drug and its role in the management of hypertension.

...

On my return from a sabbatical year in the proper and orderly Swiss canton of Geneva, I find American physicians as beleaguered as ever with problems in law and ethics. The malpractice crisis seems unabated. Physicians whom I have met express to me their ...

Disorders of the urinary concentrating mechanism vary widely in their clinical importance. At one extreme, they may simply represent an inconvenience to the patient who has to arise several times each night to urinate. At the other extreme, they cause ...

Presentation of Case

First admission. A 58-year-old left-handed accountant was admitted to the hospital because of right-sided weakness.

He was well until four months previously, when his gait became unsteady, with a tendency to fall to the right. One ...

Man, mice, cattle, mink and killer whales share, among other attributes, an autosomal recessive trait that, when homozygous, programs a disorder characterized by the presence of giant granules in diverse cells. Morphologically curious, the Chediak-Higashi ...

The pages of any book, tract or article dealing with medicine are apt to be profusely sprinkled with numerical superscripts (or their equivalents) guiding the reader to a reference list. Not only does the liberal presence of such reference numbers impart ...

A 29-year-old gravida 4, para 2, received care during her final pregnancy at three different hospitals and died three weeks post partum.

Born and having had her first delivery overseas, the patient had a criminal abortion of her second pregnancy at 12 ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Disparity between values for circulating carcinoembryonic antigen (CEA) as measured by the "indirect" radioimmunoassay on perchloric-acid-extracted plasma and the "direct" assay is a well known phenomenon to all involved in reporting out ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The recent report by Hollifield et al.¹ presents a possible explanation for the high oral doses of propranolol required to lower blood pressure in some hypertensive patients. Their findings complement observations in animals² and ...

No extract is available for articles shorter than 400 words.

To the Editor: The report by Moskowitz et al. (N Engl J Med 295:249–252, 1976) concerning the efficacy of thermography in identifying early breast carcinomas raises several questions about the experimental design used and the conclusions reached. We take ...

No extract is available for articles shorter than 400 words.

To the Editor: In the remarkable article, "Obesity in Young Men after Famine Exposure in Utero and Early Infancy," Ravelli et al. related the lower rates of obesity in men who had suffered severe famine in utero or early infancy (or both) solely to ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Byar et al. (N Engl J Med 295:74, 1976) are quite right to say that randomized clinical trials are not outmoded. Put I believe they are wrong to be ambiguous about technics that can improve on plain randomization. (I say "ambiguous" ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

SYMPOSIUM ON CANCER MANAGEMENT

The American Cancer Society, Massachusetts Division, and the Greater Boston Medical Society are presenting a symposium entitled "Successes in Cancer Management Today" on Wednesday, December 15 at the Sheraton-Boston Hotel. ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.