Suppression of glucagon secretion by glucose has been suggested as an essential component of normal glucose tolerance.^{1 2 3} In addition, hyperglucagonemia has been implicated in the pathogenesis of diabetes,^{1 2 3} in the development of diabetic ...

Partial lipodystrophy is an uncommon condition in which there is a usually symmetrical loss of fat, typically from the face, arms and trunk in a dermatomal distribution, but with retention of distal subcutaneous fat.¹ The onset is usually in childhood, ...

Megaloblastic anemia is extremely rare in the neonatal period, alerting the investigator to the possibility of a congenital abnormality of the absorption, transport or metabolism of either folate or vitamin B₁₂, or to some defect in purine or pyrimidine ...

Many reports, beginning with that of Baum et al.,¹ indicate that adenomas of the liver may occur in women taking oral contraceptives.^{2 3 4 5 6 7 8} In 1974, Nissen and Kent⁸ noted 20 such cases in the literature and added three of their own. During the ...

IT is "known" that adrenocorticosteroid therapy is frequently complicated by the appearance or reactivation of peptic ulcers,¹ and that these ulcers are often associated with bleeding and perforation.^{2 3 4} The basis for this knowledge is difficult to ...

The Mendelian Disorders

The most comprehensive catalogue of Mendelian phenotypes is that assembled by McKusick.⁵ To date, 2336 Mendelian phenotypes have been described. Of these, 1218 are autosomal dominant, 947 are autosomal recessive, and 171 are X-...

Recently, Bhattacharyya and Connor described in two sisters a lipid-storage disease, β-sitosterolemia and xanthomatosis,¹ with tendon and tuberous xanthomas appearing at an early age despite normal plasma cholesterol levels. High concentrations of plant ...

Writing on this New Year's Day, 1976, I find it difficult to look forward with great enthusiasm to the year ahead because the problems both national and international appear so daunting and the medical scene in Britain remains unhappy and confused.

The ...

Presentation of Case

A 56-year-old woman was admitted to the hospital because of hypotension.

She was well until three and half years earlier, when hypertension was found and was treated with hydrochlorothiazide. Twenty-six months before admission a ...

Those interested in the riddle of diabetes have always been intrigued by the role of the hormonal "antagonists" to insulin in the causation and maintenance of the diabetic state. An early candidate for the office of "diabetogenic factor" was, of course, ...

IN 1965, a form of chronic glomerulonephritis, now termed membranoproliferative or mesangiocapillary (MCGN), was found to be associated with depressed serum levels of the third component of complement (C3).¹ Although activation of C3 was thought usually ...

In a recent discussion of the profession's responsibility for assuring physician competence, I expressed concern that our present era of superspecialization might create "mandatory overqualification for the health care task at hand."¹

That generic ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

MINI-RESIDENCIES IN OFFICE MANAGEMENT OF EMOTIONAL PROBLEMS

The Department of Outpatient Psychiatry at the University of Kentucky Medical Center, Lexington, Kentucky, will sponsor mini-residencies in the office management of emotional problems for one, ...

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Arthur Kantrowitz, a physicist and industrial executive who is a veteran of Washington's science advisory system, has at last received official recognition for a proposal that he has been promoting for over a decade. Some say it is a sound proposal, ...