INCREASED protein loss coupled with prolonged inadequate oral intake may adversely affect the clinical course of postoperative patients.¹ Recently, improved nitrogen-sparing has been demonstrated with peripheral glucose-free amino acid infusions both in ...

PATIENTS on maintenance hemodialysis are almost invariably anemic. Although inadequate red-cell production is the predominant mechanism responsible for their anemia, some decrease in red-cell survival is also frequently found. A few well documented cases ...

THE removal of iron from patients with disabling iron overload secondary to increased iron absorption ordinarily is effectively accomplished by phlebotomy.^{1 2 3} As much as 2 g of iron can be removed from such patients every three weeks if hematopoiesis is ...

THE initial diagnosis of multiple sclerosis is usually exceedingly difficult. The clinical picture is often ambiguous when the physician first encounters the patient and, indeed, even when he first begins to suspect the diagnosis. Several laboratory ...

DR. Sheila Cassidy, a British surgeon working in Chile, claimed that, in November, 1975, she was arrested and subjected to torture by that nation's security police. During a detention of 59 days, Dr. Cassidy stated that she was tortured three times with ...

Clinical and Biomedical Applications of New Molecular Concepts in Hormone Action

Major contributions to knowledge of the mode of action of the sex steroids made over the past decade have generated a series of observations that can now be related to ...

GLUCOSE-6-phosphate dehydrogenase (G-6-PD) deficiency varies greatly in its prevalence throughout the world, in its severity between the sexes and in the actual defect among those with the disorder. Over 100 variants of the enzyme have been described, of ...

ALTHOUGH streptozotocin has been used successfully in treatment of malignant insulinomas and carcinoid tumors of the gastrointestinal tract,¹ gastrinomas have apparently not been treated with this drug to any great extent. To our knowledge only two cases ...

MEASUREMENT of serum angiotensin-converting enzyme has been found useful for confirming a diagnosis of active sarcoidosis.¹ The mean serum level in patients with active sarcoidosis is twice that found in healthy controls or in patients with other types of ...

AT present, when the new Prime Minister, Mr. James Callaghan has replaced Mrs. Barbara Castle by Mr. David Ennals as Secretary of State at the Department of Health and Social Security, it is appropriate to reflect on the way in which the character of ...

Presentation of Case

A 64-year-old woman was admitted to the hospital because of inability to walk.

She was well until three weeks previously, when she experienced a "pulling" sensation in the right groin that persisted and was accompanied by urinary ...

Thomas Huxley cautioned that "the great tragedy of Science [is] the staying of a beautiful hypothesis by an ugly fact."1 Occasionally, the observations responsible for the initial development of an hypothesis remain undisputed while new facts emerge, ...

Although clinical problems involving iron are usually associated with a deficiency of this essential element, an appreciable number of patients suffer from iron overload. This accumulation of iron can result from increased absorption, as in primary ...

Over the past 20 years, many diagnostic tests for multiple sclerosis have been described. However, none of them have proved to be specific for the diagnosis, which still rests on varied neurologic symptoms and signs occurring in characteristic remissions ...

DEATHS

Fleming — Francis James Fleming, M.D., of Belmont, died on April 9. He was in his 74th year.

Dr. Fleming received his degree from the University of Toronto Faculty of Medicine in 1926. He was a member of the American Medical Association.

He is ...

The Department annually surveys the immunization status of children entering kindergarten in Massachusetts. For 1974–75, the results¹ compared favorably with national averages² for that year but showed pockets of low immunization in the inner city. For ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Most medical students look upon physical diagnosis as their introduction to humanism in medicine. The course does serve this function, but only because students must be exposed to patients to learn the necessary skills. As a patterning ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Commissioner's Report October 1975 is a 906-page volume, based on an investigation that is stated to have cost $196,000, in which the Commissioner of the Food and Drug Administration, Alexander M. Schmidt, concludes that his agency is innocent of charges ...