CERTAIN aggressive or malignant tumors of bone such as giant-cell tumor, low-grade chondrosarcoma, fibrosarcoma or adamantinoma have the propensity for destruction of bone and local invasion of soft tissue, but have little likelihood of metastasis. Such ...

IT has been believed for some years that the administration of estrogens to post-menopausal women may decrease their risk of development of coronary heart disease.^{1 , 2} Doubt has been thrown on this belief recently, however, by evidence from the Coronary ...

DURING approximately three decades before 1970 the incidence of cancer of the uterine corpus in the United States had been stable.¹ In just the few years since that time, however, this pattern has changed dramatically.

Table 1 presents incidence rates of ...

THE results of two recent reports,^{1 , 2} each based on data from individual cases and controls, are compatible with a causal link between conjugated-estrogen use and endometrial carcinoma. A third report affirms the credibility of this link in terms of ...

LAST year Sweden adopted a nationwide patient-injury insurance program. The program resembles Worker's Compensation plans in this country; it provides compensation for patients receiving injuries in connection with medical treatment without the necessity ...

DIAZOXIDE, a benzothiadiazine derivative closely related chemically to the thiazide diuretics (Fig. 1), lacks the 7-sulfonamide group and a halogen substitution at the 6 position, does not inhibit carbonic anhydrase, and is devoid of chloriuretic and ...

TEMPORARY cardiac stimulation in the emergency resuscitation from cardiac arrest and in other less urgent conditions is generally applied by way of a pervenous endocardial electrode and an external electric pacemaker. Search for a more quickly and easily ...

OVER the past five years, there has been a steady rise in malpractice complaints from Swedish patients and this trend is expected to continue. There are three ways in which a Swedish patient can formally make a complaint and seek compensation for injury. ...

Presentation of Case

A 15-year-old girl was admitted to the hospital because of proteinuria.

She was well until nine months previously, when a routine medical examination at her school disclosed +++ proteinuria, 1 to 4 white cells and 3 to 10 red cells ...

The attempt to preserve a functional limb in treating low-grade malignant bone tumor presents a surgical challenge to anyone who must deal with such tumors. Surgeons have, after local resection, used prosthetic implants, massive autogenous transplants, ...

Perhaps the greatest single advance in the history of surgery, aseptic wound management, was conceived and advocated decades before bacteria were conclusively implicated in the genesis of wound suppuration and even before contagion was generally accepted. ...

Initially, it seemed like an isolated incident involving an un-Cooperative patient — a nonconformist; however, the subsequent reverberations were soon to rock the foundations of organized oncology, the National Cancer Institute (NCI), the Federal Drug ...

Fatal Fulminating Diabetes Mellitus

A 25-year-old gravida 2, para 0, was admitted to the hospital at about 7 p.m. at 12 weeks for threatened abortion. In the preceding 18 months, the uterus had been twice curetted for incomplete abortion, proved once ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We believe that the conclusions made by Conn and Blitzer (N Engl J Med 294:473–479, 1976) in their article on the "nonassociation" of steroid therapy and peptic ulcer are incorrect. Although they claim to produce "impressively negative" ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In 1970 Tullis reported in the Journal ¹ that 198 of 201 patients with asthma were found to harbor intestinal parasites as compared with none of 20 control patients. He wrote as follows: "From a theoretical point of view the acquisition of ...

To the Editor: Nonketotic hyperglycinemia, characterized by elevated levels of cerebrospinal-fluid glycine and neurologic abnormalities, may be due to a reduction of glycine-cleavage enzyme activity in brain.¹ The pathophysiology of the neurologic ...

No extract is available for articles shorter than 400 words.

To the Editor: Recently, two letters in the Journal debated the efficacy of resorting to high doses of antipsychotic medication early in treatment. Baldessarini and his co-workers (N Engl J Med 294:113, 1976) advocate at least two to three months of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

SCIENTIFIC PROGRAMS OF THE AMERICAN DIABETES ASSOCIATION

The American Diabetes Association will present a series of scientific programs at the San Francisco Hilton, June 20–22.

Further information may be obtained from Leonard F. Elliott, 1 West 48th ...