A human reovirus-like (HRVL) agent, also designated orbivirus, rotavirus, duovirus, and infantile gastroenteritis virus, has emerged as a major etiologic agent of acute enteritis in studies of hospitalized infants and young children in many parts of the ...

Maternal rubella infection in the first trimester of pregnancy is recognized as having a teratogenic effect. Because of the unknown incidence of asymptomatic maternal rubella, the precise risk to the fetus is not definite but appears to be high when ...

In this country, large numbers of critically ill newborn infants are transported to distant regional centers for special care.¹ Although the regional approach may have considerable influence on neonatal mortality and morbidity, a prolonged period of ...

Humoral and cellular immune responses have a decisive role in the acceptance or rejection of allogeneic grafts.¹ In clinical transplantation of kidneys, hyperacute rejections result from circulating antibodies after pre-transplant sensitizations whereas ...

The critically ill patient needs and receives enormous resources to maintain viability and progress towards a successful recovery. Personnel, time, physical and emotional effort, vast sums of money, space, highly sophisticated equipment, blood and blood ...

Past epidemiologic studies of coronary disease have shown such variables as elevated blood pressure, elevated serum cholesterol, cigarette smoking, obesity, diabetes and family history of coronary disease to be factors predictive of elevated risk of ...

Anti-A autoantibody manifested itself clinically in fatal hemolysis and kidney failure in the following case.

Case Report

A 73-year-old man suddenly experienced severe bilateral lumbar pain associated with generalized weakness, jaundice and lethargy. He ...

The uneasy truce¹ on the medicopolitical front in Britain has progressed to a rather fragile state of peace. The result of the consultants' ballot on their attitude to the government's modified proposals for phasing out private practice from the National ...

Presentation of Case

A 64-year-old man was admitted to the hospital because of renal disease.

Ten years earlier mild hyperuricemia was found. Five years later he passed a renal stone. The urea nitrogen was 14 mg, the calcium 9.2 mg, and the uric acid 7.5 ...

Some cry, "Bad Prescriptions Kill Thousands a Year," and assert that 30,000 Americans die "as a direct result" of "the drugs their doctors prescribe for them."¹ Others depreciate the seriousness of drug toxicity and point out that a drug-related fatality ...

For almost 50 years, since insulin therapy was initiated, proponents of "rigid," "tight" or "chemical" control have quoted retrospective evidence of decreased or delayed nephropathy and retinopathy as glucose levels are brought by therapy toward the ...

For many years it has been appreciated that there is an antigenic system of major importance as a barrier to successful allotransplantation. A major histocompatibility complex (MHC) of several closely linked genes is in fact present in all species studied ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The recent article by Smithline et al.¹ proposed a pathogenic role for light chains in some forms of renal tubular dysfunction. A similar pathogenic mechanism was suggested by Muggia et al.² to explain the proximal tubular dysfunction in ...

No extract is available for articles shorter than 400 words.

To the Editor: In their excellent review of neurologic disorders in renal failure, Raskin and Fishman discuss neurologic problems encountered after renal transplantation (N Engl J Med 294:204–210, 1976). They underline the importance of chest x-ray ...

No extract is available for articles shorter than 400 words.

To the Editor: I should like to add a patient with gastrinoma who responded to a histamine H₂ antagonist to the cases reported by Richardson and Walsh (Richardson CT, Walsh JH: The value of a histamine H₂-receptor antagonist in the management of patients ...

No extract is available for articles shorter than 400 words.

To the Editor: The pathogenesis of hereditary hypophosphatemic ("vitamin-D-resistant") rickets is unknown. The condition is characterized by X-linked dominant transmission and produces abnormalities in bone, kidney, intestine and parathyroid gland that ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: An editorial by B.E. Copeland¹ and a report by a Study Committee² commented negatively on the implementation of SI units in clinical chemistry and hematology.

Implementation of SI began in 1958 and, after several revisions^{3 4 5 6} the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This book is the first of a series designed to explore the relevance of modern cell-membrane studies to problems of human disease. Investigators familiar with the field of membranes would have little difficulty in pointing out areas where more progress in ...

No extract is available for articles shorter than 400 words.

This book is about liaison psychiatry, a designation likely to puzzle most physicians. It is actually a new label for an area of psychiatric activity that has been around for 40 years, but developed mostly in the last decade. Liaison in this context ...

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Immunology

Current Topics in ...

SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL REVISED SCHEDULE

There is a change in the May 25 Seminar to be held at 4:00 p.m. in the George Sherman Auditorium, Beth Israel Hospital, Boston. Dr. Kenneth Sterling, Columbia University College of ...

No extract is available for articles shorter than 400 words.