METHYLMALONIC acidemia was described in 1967,^{1 , 2} and at least 20 children with this inherited disease have now been reported on. The disorder is characterized clinically by recurrent vomiting, failure to thrive, developmental retardation, hepatomegaly, ...

INFECTION in man by the hepatitis B virus may result in clinical syndromes with varying degrees of severity and chronicity. The majority of patients with acute Type B hepatitis recover and eliminate HB_S Ag from their circulation. However, in 10 to 15 per ...

SALICYLATE therapy for children with rheumatic fever requires careful dosage adjustment to obtain the desired anti-inflammatory and analgesic effects with a minimum of adverse reactions. Serum salicylate concentrations must be maintained within a ...

DURING the past year, there has been considerable conflict between internal medicine and family practice. The Association of American Medical Colleges Institute on Primary Care in October, the annual meeting of the Association and the annual meeting of ...

(Second of Two Parts)

Evidence Relating Brain Catecholamines to Specific Neurologic Diseases

Parkinson's Disease

The role of catecholamines in Parkinson's disease has been examined more extensively than in any other neurologic disorder. Since several ...

Introduction

LUNG-FUNCTION testing has an important role in the assessment of patients with a variety of cardiorespiratory disorders. A number of tests are now performed routinely in most teaching hospitals. The commonest are measurements obtained by ...

PLATYPNEA (dyspnea produced by assumption of an erect position and relieved by a recumbent one¹) as a post-pneumonectomy complication has rarely been observed in the past.² In the patient described below, severe platypnea and orthostatic cyanosis ...

UNILATERAL pulmonary edema has been described after re-expansion of pneumothorax,¹ in congenital heart disease,² after thoracentesis³ and in failure of the left side of the heart.⁴ The two cases reported below shortly followed renal transplantation.

Case ...

EVERY war finds heroes on opposing sides, but in the heat of conflict, very often the contestants lose sight of the valor of their opponents. However, among Boston's doctors, in the days of the Revolution, even the British admired and trusted the high-...

Presentation of Case

A 68-year-old man was admitted to the hospital because of loss of consciousness.

Four years previously he began to experience difficulty in keeping his eyes open, slowing of motor activity and imbalance on walking. A physician ...

Among the many advances in human genetics, treatment has probably been the least publicized. The definition of previously unrecognized pathologic entities, the documentation of their fundamental molecular enzymatic nature, and control in families at risk ...

The enigmatic nature of Crohn's disease periodically elicits plaintive cries for new concepts.¹ Students of inflammatory bowel disease, struggling with this group of disorders of unknown causes, clutch at methods that appear to have worked for others. ...

Scientific observations are often called into ethical question, when they are based on the study of sick and suffering people. This criticism remains true even though there have been many occasions when the study of the sick has brought help not only to ...

No extract is available for articles shorter than 400 words.

IMPORTING TUBERCULOSIS — A PARADOX

The supposed contribution of aliens to the problem of tuberculosis in Massachusetts is a perennial complaint of local health agencies and individual citizens. The subject and some description of the real culprits have ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We should like to clarify misinterpretations of our data¹ contained in the recent article by Low-Beer et al. entitled "Abnormalities of Serum Cholecystokinin and Gallbladder Emptying in Celiac Disease."² The authors report that we ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: As members of the National Health Service Corps, we are personally involved in efforts to improve the quality of primary health care.¹ We noted with interest the report of efforts at the Beth fsrael Hospital to establish a primary-care ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This small volume is based on 45 cases, which the authors studied personally, as well as approximately 200 references to previously published works on this subject. In general, the authors have lived up to their attempt to restrict their data to the years ...

No extract is available for articles shorter than 400 words.

Readers brought up in the tradition that the paragraph is the unit of scientific discourse and the sentence the unit of scientific thought may be put off by this book — and may even consider it a non-book. But to be curtly dismissive on the basis of past ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

WHITE HOUSE FELLOWSHIP PROGRAM

The President's Commission on White House Fellowships has announced the availability of fellowships designed to be a one-year sabbatical in public service. Fellows will serve as special assistants to the Vice President, ...