THERAPY of meningitis caused by gram-negative bacilli of the pseudomonas and enterobacteriaceae groups is complicated by the frequent resistance of the infecting organism to multiple antimicrobial agents and by the failure of most antimicrobials, when ...

CROMOLYN sodium inhalation frequently leads to transient upper airway irritation resulting in brief paroxysms of coughing.¹ More persistent manifestations of adverse reactions to cromolyn appear rarely² and include skin eruptions¹ and pulmonary ...

HUNTINGTON'S disease is a neurologic disorder that is clinically characterized by chorea and dementia. It is transmitted in an autosomal dominant fashion with complete penetrance. The major neuropathologic sign is a loss of neurons from the basal ...

BETA₂ microglobulin, a low-molecular-weight (11,700 daltons) protein constituent of cell membranes, is secreted by lymphocytes and other cells, and is normally present in low concentration in serum, bodily fluids and secretions. It is structurally ...

ALTHOUGH milk intolerance has been recognized for centuries, the role of lactase deficiency was established only during the past decade.^{1 2 3} The definitive diagnosis of lactase deficiency requires collection of a biopsy specimen from the small intestine ...

(Second of Three Parts)

Coronary Heart Disease

In coronary heart disease, there is evidence that platelets may be involved, both by their incorporation into occlusive thrombi and by embolization of aggregates into the microcirculation.3–5,^{38 , 39}

The ...

THE measurement of urinary sodium, potassium and chloride has become an increasingly common practice in hospitalized patients. Despite their widespread acceptance, however, it is clear that these laboratory tests often yield information that is either of ...

RAPID movement of glucose across the cell membrane obligates the movement of a sufficient amount of water to maintain osmotic equilibrium. Clinically, the rapid movement of glucose from the extracellular-fluid compartment to the intracellular-fluid ...

The health-care system of this country is a staggering enterprise, in any sense of the adjective. Whatever the failures of distribution and lack of co-ordination, it is the gigantic scale and scope of the total collective effort that first catches the ...

Presentation of Case

A 41-year-old woman was admitted to the hospital because of acute renal failure.

She was well until four weeks previously, when she had a flu-like illness, with fever and rhinitis but without a sore throat. One week later night sweats ...

Beta₂ microglobulin (β2m) as isolated and characterized from human urine by Berggård and Beam in 1968.¹ Though initially of interest largely as an index of renal tubular function, β2m has attracted widespread attention in recent years as a result of the ...

One of the most exciting and potentially one of the most important developments in gastroenterology of recent years is the possibility of medical dissolution of cholesterol gallstones. Gallstone disease afflicts 10 to 20 per cent of the world's population,...

Most medical communications are difficult to read. To determine why, contributions to three issues of the New England Journal of Medicine were studied, and the prose analyzed.

Materials and Methods

Articles were taken from the Journal issues dated April 4,...

No extract is available for articles shorter than 400 words.

Home health care in Massachusetts is provided by Visiting Nurse Associations, by the nursing component of city or town public-health departments or by the home-care program of a hospital. Of the 157 certified agencies, 66 per cent are voluntary, nonprofit ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We read with interest the study of Holmes and his colleagues¹ and the subsequent correspondence.^{2 , 3}

Since January, 1974, we have isolated chlamydia from 182 (31.2 per cent) of a selected group of 572 women attending clinics for sexually ...

No extract is available for articles shorter than 400 words.

To the Editor: Gupta and Siegal¹ report that incubation of Ficoll–Hypaqueisolated human lymphocytes with human amniotic fluid decreases E-rosette formation. They suggest further that alpha fetoprotein is probably the active protein in this phenomenon and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A prospective study was undertaken to estimate the frequency of chondrocalcinosis articularis and periarthritis of the shoulders in 200 diabetic and 100 nondiabetic patients, the latter seen at the outpatient clinic for internal medicine. ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Most physicians are familiar with the facts of the Minamata tragedy, which the Smiths examine closely in this extensive photoessay. The Chisso Corporation, a Japanese chemical manufacturer with a plant in the town of Minamata, had long been dumping its ...

INTERNATIONAL COLLEGE OF SURGEONS MANUSCRIPT AWARD

The Obstetrics and Gynecology Specialty Group of the International College of Surgeons announces the biennial manuscript competition. The winning author will present his paper at the International ...