EPSTEIN–BARR virus (EBV) can cause infectious mononucleosis,¹ a benign, self-limited lymphoproliferative disease marked by the appearance of atypical lymphocytes in the peripheral blood. The virus is also associated with two neoplasms² — Burkitt's ...

RECENT evidence suggests that the relative or absolute risk of endometrial cancer is increasing.^{1 , 2} Furthermore, the range of indications for estrogen therapy in menopausal and post-menopausal women appears to be expanding. We therefore investigated the ...

BETWEEN 1962 and 1973, dollar sales of estrogen quadrupled in the United States.^{1 , 2} Conjugated estrogens (Premarin, Ayerst Laboratories) containing principally sodium estrone sulfate constituted the vast majority of the quantity supplied. A recent ...

THE presence of an unusual fast-moving hemoglobin (Hb) in the red cells of patients with diabetes mellitus was first reported by Rahbar.¹ Further investigations showed that this component had the same Chromatographic and electrophoretic properties as Hb A_...

(First of Three Parts)

THE concept of pharmacologic inhibition of platelet reactivity as an approach to antithrombotic therapy has gained considerable support with the recognition of the important role of platelets in thrombus formation, and the ...

CLONIDINE (Catapres, ST-155) recently became available for use by prescription in the United States as an antihypertensive drug. It is highly effective in patients with either moderate or severe hypertension, but the magnitude of response cannot be ...

ENDOSCOPIC retrograde cholangiopancreatography has been widely accepted as a diagnostic tool in pancreatic and biliary-tract disease.^{1 2 3} The ability to define ductal anatomy and pathology and to pass instruments through the endoscope into the biliary ...

TWO earlier columns this year recognized the malpractice insurance crisis of 1975. These writings were primarily analytical, since legislative reaction had not yet occurred except in a few states. Now, in the late autumn, most of the year's activity in ...

CARDIAC hyperfunction, when sustained, commonly leads to a decline in myocardial contractility. Long standing hemodynamic overloading, whether it is due to systemic or pulmonary hypertension, valvular heart disease or loss of functional myocardial tissue (...

Presentation of Case

A 64-year-old man was admitted to the hospital because of a fever of unknown origin.

At the age of 16 years he was found to have pulmonary tuberculosis and was admitted to a sanatorium, where he was treated with repeated left ...

A possible causal or contributory association of estrogenic hormones with carcinoma of the endometrium and breast in the human being has been suspected for many years.¹ These suspicions have been founded upon the demonstration of estrogen-induced cancer ...

Since cellular proliferation is necessary for carcinogenesis, it seems reasonable that the hormones responsible for proliferation of endometrial cells, the estrogens, should in some way be involved in the genesis of endometrial cancer. A substantial body ...

Ambivalence concerning the perceived role of the house officer in the teaching hospitals of this country is about to be laid to rest. Whether or not the Department of Labor grants independent labor-union status to the Physicians National House Staff ...

COMMITTEE ON MATERNAL WELFARE

Placental Insufficiency Causing Fetal Death

After an uncomplicated prenatal course, a 27-year-old gravida 2, para 1, was admitted to the hospital at 41 weeks with bleeding and in labor, one hour after spontaneous rupture of ...

To the Editor: It is established that some adults react adversely to monosodium glutamate and get "Chinese-restaurant syndrome."^{1 2 3 4 5} We have found that children seem to describe similar symptoms with almost the same degree of prevalence. The three ...

To the Editor: In his recent review (N Engl J Med 293:280–285)

Dr. Shand suggested that the importance of hypoglycemia associated with propranolol therapy had been exaggerated, except in insulin-treated diabetic patients. A recent literature search by us ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The Colton paperback on statistics in medicine is the newest entrant to the growing market for statistics books in the health sciences. The book is divided into three parts: fundamentals; statistical inference; and statistics in medical research. Of these ...

MASSACHUSETTS DEPARTMENT OF PUBLIC HEALTH CRETINISM SCREENING PROGRAM

Effective in January, 1976, the Metabolic Disorders Program of the State Laboratory Institute will begin routine screening for hypothyroidism in newborn infants in Massachusetts. The ...