ALTHOUGH the cause of rheumatoid arthritis is unknown, immunologic mechanisms appear to play a major part in its pathogenesis. The immune system can be divided into humoral or thymus-independent B-lymphocyte reactions, which are mediated by antibodies, ...

REPORTS of the clinical value of the limulus amebocyte lysate test for the detection of endotoxemia in man are discordant. Two groups of investigators have found the test to be a reliable and useful method for the detection of endotoxemia.^{1 2 3 4 5} Three ...

"TOO much gas" causing abdominal pain and bloating is probably the most common gastrointestinal complaint encountered in medical practice. An unusual feature of this complaint is that the patient provides the physician not only with his symptoms but with ...

SEVERAL studies have suggested that physician assistants are well accepted by patients¹ and physicians,² increase the productivity of medical practice, improve access to health services and enhance quality of care.^{3 , 4} However, the ultimate test of the ...

(First of Two Parts)

THE blood platelets, approximately 2 μm in diameter and numbering 200,000 to 400,000 per cubic millimeter, are produced in the megakaryocytes of the bone marrow by the coalescence of cytoplasmic membranes formed by invaginations of ...

THE aim of these two papers is to describe briefly the use of exercise testing in patients with respiratory problems. In the first, the background will be covered as an introduction to the available methods; a description of the normal response will set ...

THE outlook of the laboratory has dominated medical education over the past 25 years in part because of the large amount of money available for research. Considered by academic physicians as much a Scythian mound as a Parthenon, the National Institutes of ...

Presentation of Case

A 23-year-old man was admitted to the hospital because of stupor.

Information about him was limited, but he was reported to have been well until one month previously, when he experienced two or three episodes of transitory pain in the ...

Rheumatoid arthritis is a common systemic disease of unknown cause in which the predominant symptoms and changes occur in articular and related structures. The disease is accompanied by the three classic hallmarks of inflammation — rubor, tumor and dolor —...

IN 1971, the Department of Health, Education, and Welfare initiated research to evaluate the impact of the primary-care physician's assistants on the practitioners and practices in which they were functioning, the quality of care delivered, the ...

Since the National Intern and Residency Matching Plan was established in 1951, it has distributed more than 180,000 interns to hospitals in the United States. This plan has brought order to a process that was confused and unwieldy for both students and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Maki et al. recently reported a case of candidemia due to a scalp-vein needle (Maki, Drinka, and Davis: Suppurative phlebitis of an arm vein from a scalp-vein needle. N Engl J Med 292:1116–1117, 1975). We have encountered a case of ...

No extract is available for articles shorter than 400 words.

To the Editor: Spontaneous bleeding into the anterior chamber of the eye without apparent cause is most unusual in adults. We have seen one such hyphema occurring during hemodialysis in a 32-year-old woman with a long history of chronic hypertension, ...

To the Editor: In his recent editorial, "Cancer Research — Controversy, Progress and Prospects" (in the July 17 issue), Dr. Frei seems to have ignored any mention of cancer prevention in his zeal to convince us that we are well on our way to curing these ...

To the Editor: Dr. Welch, in his Special Article (N Engl J Med 292:1374, 1975) is to be congratulated for his generally comprehensive overview of many of the present problems and facets of the medical-malpractice issue. Although he does not use the word ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Pediatrics

Behavioral Pediatrics ...

No extract is available for articles shorter than 400 words.

SYMPOSIUM ON DIET AND DISEASE

A symposium, entitled "Diet and Disease," sponsored by the Jewish General Hospital, Montreal, will be held at the hospital on Wednesday, October 8.

Further information may be obtained from the Office of Medical Education, ...

No extract is available for articles shorter than 400 words.