THE problem of anticoagulant therapy in acute myocardial infarction is still one of the most controversial issues in medical practice.^{1 2 3 4 5 6 7 8} Despite an extraordinarily large number of individual follow-up studies and sophisticatedly designed ...

THE enthusiasm that accompanied the introduction of anticoagulants for patients with acute myocardial infarctions has cooled considerably during the past decade. Much of present opinion can be summed up in a statement made in a review article by Gross et ...

CLINICAL investigators from three countries recently presented data suggesting a causal link between rauwolfia antihypertensive drugs and female breast carcinoma.^{1 2 3} Each study compared the prevalence of drug use before diagnosis in cases of breast ...

SUDDENLY the term "medical malpractice" has become familiar to the public. Journals and newspapers proclaim that a true crisis has developed. Staggering rises in medical costs are predicted if adequate protection for the public is to be maintained.

This ...

(Second of Two Parts)

Gastrin in Human Disease

Hypergastrinemia without Gastric Hypersecretion

Pernicious anemia; atrophic gastritis. Serum gastrin concentrations are increased in patients with atrophic gastritis. The increase is especially marked in ...

SOMATOSTATIN has been reported to diminish basal insulin levels¹ and to inhibit insulin secretion stimulated by glucose,² arginine,³ glucagon,⁴ and tolbutamide⁴ in normal man. These effects of somatostatin administration have not been associated with ...

SURGICAL intervention for control of massive renal hemorrhage after trauma generally results in nephrectomy, or at least, heminephrectomy.^{1 , 2} We have shown recently that in blunt trauma with persistent hemorrhage angiographic injection of autologous ...

EOSINOPHILIC gastroenteritis is an uncommon digestive disease. Although it is often regarded as allergic in origin, trials of elimination diet generally have been unsuccessful, and relatively little evidence for an allergic mechanism has been presented. ...

WHEN the function of the laryngeal sphincter is lost, anything swallowed, including saliva, is directed through the incompetent larynx and into the trachea. The cough mechanism is impaired, and vocal function is nil or absent. Frequent bouts of aspiration ...

THE General Medical Council was established in accordance with the requirements of the Medical Act of 1838, which stated that it was "expedient that persons requiring medical aid should be enabled to distinguish qualified from unqualified practitioners." ...

Presentation of Case

A 59-year-old man entered the hospital because of dyspnea.

He was well until two and a half years previously, when edema of the penis and scrotum developed, and evaluation at another hospital revealed a tumor of the bladder. At ...

And now, under the aegis of the editor who has helped assemble two anthologies of Controversy in Internal Medicine, ^{1 , 2} the Journal presents a pair of papers (pp. 1359 and 1362) that can evoke almost enough new controversy to fill a third volume.

One of ...

Does coffee drinking predispose to coronary-artery disease?

May oral antidiabetic agents curtail rather than prolong life?

Do the common tranquilizers meprobamate and chlordiazepoxide, if taken by a pregnant woman, harm the fetus?

Does reserpine make a ...

A new technic is invariably surrounded by an aura of almost ritualistic mystique that can only gradually be eroded by the passage of time. One can imagine that after several decades of exhaustively controlled and supervised rocket launches, the day will ...

As a direct provider of patient care, and as the state agency responsible for health protection and regulation, the Department of Public Health occupies a dual role with some inherent conflicts. Seven departmental hospitals* operate a total of just over ...

To the Editor: Streeten et al. have provided evidence for the potential diagnostic usefulness of the angiotensin II antagonist, 1-sar-8-ala-angiotensin II (saralasin, P-113) in the recognition of "angiotensinogenic" hypertension.¹ Though the authors ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In neuronal ceroid lipofuscinosis with curvilinear bodies, the systemic nature of the disease is well documented, and diagnosis of the disease by electron microscopy of muscle, nerve and skin biopsies and appendectomy has been ...

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Anatomy and Histology

The Anatomy ...

COURSES ON LASERS

The Medical Laser Laboratory of the University of Cincinnati Medical Center, in co-operation with the Laser Institute of America and the Southwest Center of the Technical Education Research Centers will sponsor a course entitled "...

No extract is available for articles shorter than 400 words.

When Senators Kennedy, Goldwater, and Javits line up with Vice-President Rockefeller in support of a proposal by President Ford, it may be concluded that the matter at hand is of an inconsequential ceremonial nature or that something with a lot of power ...