FEW topics in medicine are more widely debated than the obstetric management of prolonged rupture of the fetal membranes (PROM). Some physicians advocate termination of pregnancy within a specified, brief period after rupture of the membranes.¹ Others ...

IN experimental animal systems, acute destruction of solid tissue allografts is mediated primarily by lymphoid cells. Morphologic studies of rejecting grafts have demonstrated lymphoid infiltration that is initially localized to perivascular regions and ...

THE ductus arteriosus is a large channel through which, during fetal life, about 60 per cent of the combined output of the two ventricles passes from the pulmonary trunk to the descending aorta.¹ The ductus arteriosus is functionally closed by ...

ELEVATED concentrations of glycine in plasma are encountered in a variety of metabolic disorders of infants and children. In the ketotic-hyperglycinemia syndrome, elevations of glycine levels in blood seem to be secondary to the accumulation of one or ...

THE authors of scientific papers commonly complain about how long it takes to get their papers published and how outdated the published findings are. This publication delay has been studied for several fields, including psychology,^{1 2 3} but apparently not ...

FOR many years, experts in the field of health have proposed that specific aspects of life-style, such as diet, physical activity, cigarette smoking, and consumption of alcohol, have an important influence on morbidity and mortality. Recent studies ...

IF portraits could only talk! That is the thought that comes to us as we stroll around the fifth-floor gallery at the Countway Library, with its imposing array of medical Worthies calmly gazing back at us from their handsome, gilt frames. Some of the ...

Presentation of Case

A 59-year-old woman was admitted to the hospital because of dyspnea.

In her youth she had had multiple attacks of pneumonia. For many years she had been treated intermittently with iron because of anemia. Twenty years before admission ...

It is difficult to believe that the respiratory-distress syndrome, perhaps the major cause of infant mortality in the United States today, was given only cursory attention in the standard pediatric textbooks of the early 1950's. But during the next 20 ...

From time to time nonsurgical technics have been proposed for the treatment or palliation of certain congenital heart defects. These have included a modified cardiac catheter used to relieve pulmonary and tricuspid-valve stenosis,¹ catheter closure of ...

IN this issue, Charles Hickling Bradford (M.D., Harvard, 1931), son of former medical-school dean Edward H. Bradford (M.D., Harvard, 1873), writes the first of a series of lively essays on New England's Revolutionary physicians. Bradford, himself a true ...

To the Editor: Dr. Lee Wood, in 1972,¹ and again recently (issue of March 6, 1975), casts doubt on the value of controlled trials to evaluate aspirin in the prevention of myocardial infarction. He suggests a study of changes in mortality in a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Infectious mononucleosis is believed to be transmitted among young adults primarily through kissing¹; its incubation period is said to be no more than 50 days,^{1 , 2} and susceptibility to the infection is indicated by the absence of ...

To the Editor: Melancon and Nadler^{1 2 3} reported the presence of fructose-1, 6-diphosphatase (FDPase) activity in human leukocytes, a finding that could not be confirmed by Cahill and Kirtley.⁴ Because leukocytes are more convenient to obtain than a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: My call for more objective assessment of risk factors in community-wide screening campaigns for Fay-Sachs disease¹ was greeted with a chorus of disapproving letters, published^{1 , 2} and unpublished. In spite of the title, "Doubtful Benefits ...

To the Editor: Since the publication of a report by Safer et al. (N Engl J Med 287:217, 1972), which called attention to a depression of growth in hyperactive children on stimulant drugs, the controversy regarding the use of amphetamines and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

FELLOWSHIP IN CLINICAL AND TUMOR IMMUNOLOGY

A one- or two-year fellowship in clinical and tumor immunology and immunotherapy is available at the University of California, San Francisco, starting July 1.

Further information may be obtained from Dr. Lynn E. ...

No extract is available for articles shorter than 400 words.