HUMAN diabetic ketoacidosis is characterized by overproduction of glucose and ketone bodies in the liver¹ and by excessive mobilization of free fatty acids from adipose tissue.² These metabolic derangements are thought to result primarily from severe ...

CHILDREN infected in utero with rubella may later have multiple congenital defects, including cataracts, retinal pigmentation, deafness, cardiac anomalies and microcephaly.^{1 2 3 4 5 6} This disorder is nonprogressive.^{4 , 5} During the past year we have ...

THE congenital rubella syndrome consists of protean clinical manifestations, many of which relate to the central nervous system.^{1 2 3} Most of these cases with involvement of the nervous system appear during the neonatal period or the first year of life ...

THERE have been several accounts of Chinese medical education in the medical literature.^{1 2 3 4 5 6 7} In the wake of the Cultural Revolution (1966–1969) most parts of the Chinese educational system have undergone a drastic transformation, and since ...

ALTHOUGH the orbit is not a common site of involvement in most diseases, exophthalmos and other orbital abnormalities are associated with a surprisingly wide variety of systemic and local conditions. Therefore, it is important to be familiar with ...

IN 1960 an Rh Antepartum Clinic was organized at the Columbia–Presbyterian Medical Center to make a more complete and prospective study of the natural history of Rh disease and to apply and evaluate new methods of management and prevention.^{1 , 2} All ...

Presentation of Case

First admission. A 52-year-old woman was admitted to the hospital because of bacterial endocarditis.

The patient was known to have a heart murmur since the age of seven years. She was in excellent health until four months before ...

In mammals, selective insulin deficiency, whether induced by administering alloxan or streptozotocin or by infusion of insulin antiserum, produces the same pattern of metabolic change as surgical pancreatectomy, a circumstance in which both insulin and ...

The rubella syndrome continues to expand. In 1941, Sir Norman Gregg associated cataracts, microphthalmia, cardiac malformations, and failure to thrive with a history of maternal rubella.¹ Soon, deafness, microcephaly, and mental retardation were added to ...

I recently gave a lecture-demonstration to a class of medical students taking clinical physiology (a preclinical course). I wished to present two patients with Graves's disease: in anticipation of the session I requested that white coats be worn by the ...

No extract is available for articles shorter than 400 words.

To the Editor: In his article, "Neonatal Nonhemolytic Jaundice"(N Engl J Med 292:194–197, 1975), Dr. Johnson makes the statement that "there appears to be a high rate of cirrhosis in infants with neonatal hepatitis who have undergone exploratory ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: From their controlled trial, the Copenhagen Study Group for Liver Diseases concluded that in patients with cirrhosis of the liver, prednisone therapy is only beneficial for nonalcoholic females without ascites.¹ For nonalcoholic males no ...

To the Editor: Eriksson and Larsson and Weiser et al. (issue of January 23, 1975) discuss the accumulation within the cisternae of the rough endoplasmic reticulum (RER) of PAS-positive material cross-reacting with alpha1-antitrypsin (A₁AT) antibody and ...

No extract is available for articles shorter than 400 words.

To the Editor: We read with interest the paper of Abdou et al. (N Engl J Med 291:1271–1275, 1974). Using the E-rosetting technic,¹ we found in three normal thymusesa mean value (±S.E.M.) of 93.4 ± 1.4 per cent of T lymphocytes, as compared to a value of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The two letters defending the United Kingdom's NHS (N Engl J Med 292:374, 1975) require serious comment before they are taken as valid evidence in favor of a nationalized health-care system. Being a graduate of University College, Dublin, ...

To the Editor: As an advocate of randomized clinical trial as the only reliable method so far designed to distinguish between therapies that are not overwhelmingly different, I should like to comment on the article, "Allocation of Subjects in Experiments"...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

194th ANNIVERSARY MEETING May 27 and 28, 1975 Statler Hilton, Boston

Current Trends in Coronary Heart Disease

TUESDAY MORNING, MAY 27

8:30 Panel: Risk Factors in Coronary Disease

William B. Kannel, M.D., Chairman; co-director, Framingham Study, NIH; ...

INTERNATIONAL UNION AGAINST CANCER

The International Union Against Cancer has announced the availability of the following two programs to further research on cancer.

The Yamagiwa-Yoshida Memorial International Cancer Study Grants, intended to encourage ...