LINEAR deposition of IgG on renal tubular basement membrane, suggesting the presence of anti-tubular-basement-membrane (anti-TBM) antibody, has been detected in kidney from patients with anti-glomerular basement-membrane (anti-GBM) antibody disease,^{1 2 3} ...

ACRODERMATITIS enteropathica, an autosomal recessive inherited disorder of unknown causes characterized by severe diarrhea, dermatitis, and alopecia, begins in infancy, often coincident with the change from breast milk to cow's milk. Since 1953, a highly ...

RECENT evidence obtained in our laboratories indicates that chronic morphine or methadone administration produces a pronounced reduction in the size and secretory activity of the male rat's secondary sex organs.^{1 , 2} An 87 per cent reduction in serum ...

IN 1967, it was reported that vitamin E deficiency in the premature infant was associated with hemolytic anemia.¹ Confirmatory reports subsequently appeared from this country,^{2 3 4} as well as from Italy,⁵ and Switzerland.⁶ The typical syndrome, which ...

HEALTH care in America has been the subject of many thoughtful reviews.^{1 2 3 4} There is general agreement that some reorganization of the medical-care system is essential to reach underserved populations. However, this goal is much easier to conceive than ...

(Second of Two Parts)

Current Problems

Success or Failure of Marrow Engraftment and Marrow-Graft Rejection

A review of the literature of human marrow transplantation before 1967 showed a high incidence of complete failure of engraftment.¹¹³ Failure of ...

Weaning from Intermittent Positive-Pressure Ventilation

Criteria

THE criteria for the discontinuation of controlled ventilation are the converse of those for the institution of controlled ventilation. The patient should have an alveolar arterial oxygen ...

I WAS traveling recently with a medical colleague who had been involved in negotiations with representatives of the trade unions whose members had been engaged in disruptive activities in his hospital as part of their campaign to eliminate private ...

Presentation of Case

A 53-year-old woman was admitted to the hospital because of a lytic lesion of the right femur.

She was well until 13 years previously, when she noticed a painless mass in the right thigh, which did not change in size subsequently. Ten ...

Despite a distinctive immunofluorescence picture, anti-TBM antibody accumulation in human renal disease was recorded only after descriptions of experimental models of anti-TBM disease. Immunization of guinea pigs or certain strains of rats with ...

Dietary standards, such as the Recommended Dietary Allowances (RDA),¹ are used for two primary purposes —to plan diets for individuals or groups of people, and to evaluate the nutritional adequacy of the foods eaten. Although much has been written about ...

Do PSRO regulations reflect the ultimate extent of controls over the hospital practice of independent staff physicians? No, far from it. An emerging legal doctrine, "hospital corporate responsibility," promises far more stringent standards for quality ...

Comparable data on what the 351 cities and towns in Massachusetts do for, and spend on, local public-health needs have never been available. The now outdated Manual of Recommended Minimal Standards emphasized enforcement of the State Sanitary Code, the ...

To the Editor: The paper, "Lidocaine in the Prevention of Primary Ventricular Fibrillation" (N Engl J Med 291:1324–1326, 1974), by Lie and his colleagues must be viewed as re-emphasizing the necessary prophylactic use of lidocaine in every patient ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Two letters published in the October 10, 1974, issue of the journal ^{1 , 2} report the effectiveness of deanol acetamidobenzoate (Deaner, Riker) in reducing tardive dyskinesia in three patients. Since the use of this drug for persistent ...

To the Editor: Creutzfeldt-Jakob disease is a form of dementia probably caused by a slow or persistent virus.¹ In the laboratory, the disorder can be transmitted to susceptible animals by inoculation of brain.² The incubation period averaged 11 to 14 ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

UNIVERSITY ASSOCIATION FOR EMERGENCY MEDICAL SERVICES

The Association's annual meeting will be held at the Bayshore Inn, Vancouver, British Columbia, May 20–24. The fee is $60($30 for residents).

Further information may be obtained from Arthur E. Auer, ...

No extract is available for articles shorter than 400 words.

Congress and Science: A Querulous Spirit Emerges

Baseless paranoia has so often infested the scientific community's assessment of how it stands with the U.S. Congress that one hesitates to report that Capitol Hill has lately been stirring with strange and ...