THE major cause of death in patients whose bone-marrow function is compromised by neoplastic disease, chemotherapy or radiation therapy is infection, which, despite the use of broad-spectrum antibiotics, still accounts for the majority of deaths in ...

THE preponderance of hepatitis after blood transfusion is unrelated to the hepatitis B virus.^{1 2 3} The cause of the hepatitis B surface antigen-(HB_s Ag)-negative transfusion-associated hepatitis is not definitely known. Hepatitis A virus has often been ...

TRANSMISSION of the hepatitis B virus from carrier mothers to their offspring has been considered a possible route for spread of infection that might explain the maintenance of the virus in populations before the use of needles and transfusions. Stokes,¹ ...

WE previously reported the presence of an unusual DNA synthetic enzyme, known as terminal deoxynucleotidyl transferase (TdT), in the circulating blast cells of a child with acute lymphoblastic leukemia.¹ Until then, this unique type of DNA polymerase had ...

THE medical-care literature is replete with empirical studies reporting that persons enrolled in prepaid group practices use a greater volume of ambulatory-care services and, perhaps as a consequence, a lesser volume of inpatient services than comparable ...

ALTHOUGH hormone therapy for breast cancer has been in use for decades, there is much confusion about the reasons for its effectiveness (incomplete though it is). Patients respond in about equal numbers to oophorectomy, adrenalectomy, or hypophysectomy, a ...

IT is hard for me to believe that the 1930's are as far from the present as the gay 90's were from my youth, but the current movies prove it to me. I find these movies bittersweet because a camera uncluttered by reality shows the cities and people of my ...

This compilation of the normal laboratory values used for the Case Records of the Massachusetts General Hospital is presented to familiarize physicians with data in SI units. The data previously published (N Engl J Med 290:39–49, 1974) are compared in ...

The article by Higby et al. in this issue of the Journal is the tip of an iceberg of long standing efforts in granulocyte replacement.

Treating infections due to leukopenia with transfusions of leukocytes has been seriously considered ever since ...

Terminal deoxynucleotidyl transferase (TdT) is an enzyme that catalyzes the elongation of preformed oligomeric or polymeric DNA chains by adding deoxyribonucleoside monophosphates to the 3′-OH ends of these chains.¹ It was discovered independently by ...

Slowly but surely, grains, drachms, ounces and pounds, and inches and feet, have disappeared from the pages of the Journal, and metrication will probably supersede in spite of wiseacres who demand, "don't give them another 2.54 centimeters." In the 30's, ...

VARAZTAD H. KAZANJIAN, M.D.

Unusual longevity was appropriate for the unique Varaztad H. Kazanjian, alumnus of both the Harvard Dental and Medical schools, who died at home in Belmont, Massachusetts, on October 19, 1974, at the age of 95. A founding ...

Longevity occasions two major concerns to state and local health departments. The first is to provide adequate services for the elderly. The second is how to pay for them.

The service aspect has much improved over the last decade. Yet the psychologic, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The pathogenesis of many forms of corneal cloudiness and retinitis pigmentosa in human beings is unclear. Some interesting correlates of abnormal urinary mucopolysaccharide (MPS) or glycoprotein excretion may, however, be found with regard ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: I hope that the plea so eloquently made by Drs.

Peterson and Cerami (January 16 issue of the Journal) for more drugs for the treatment of rare diseases will bring about a greater response than my own effort of one year ago.¹ The Lancet,² ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This textbook is divided into seven sections that cover the biology of benign prostatic hypertrophy and neoplastic hyperplasia (L.M. Franks), medical therapy of benign hypertrophy (J. Geller), surgical management of hypertrophy (J.P. Mitchell), ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

I am glad I am not a social scientist. Social scientists take themselves so seriously. They speak soberly of their "discipline." Their research is serious business even if it only proves what everyone already knows (e.g., that most nursing-home patients ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

ELI FRIEDMAN MEMORIAL LECTURE

The second Eli Friedman Memorial Lecture will be given in the Harriet MeCormack Building auditorium, Boston City Hospital, on Wednesday, May 7, at 4:30 p.m. Dr. Richard Goldbloom, professor of pediatrics at Dalhousie ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.