Follow Topic:
SpecialtySurgery

and Others
In this trial involving women with symptomatic fibroids who were planning to undergo surgery, treatment with the selective progesterone-receptor modulator ulipristal acetate was effective in controlling excessive bleeding and reducing fibroid size at 13 weeks.

and E.J. Nilles
A 23-year-old man who had been a passenger in a minivan was brought to the ER after a high-speed road accident. He had transient hypotension and tachycardia, which improved after the administration of intravenous fluids.
- Free Full Text
Interactive Feature
This interactive feature presents the case of a 39-year-old woman at 32 weeks of gestation with lower and middle back pain that radiated to the upper abdomen and episodes of vomiting.
Direct the investigation of the case, test your diagnostic and therapeutic skills, and compare your performance with that of others.

and Others
In this trial comparing oral ulipristal acetate (5 mg or 10 mg daily) with once-monthly leuprolide acetate in women with symptomatic uterine fibroids before planned surgery, both doses of ulipristal acetate were noninferior to leuprolide acetate in controlling uterine bleeding.
- CME
In this case report, Staphylococcus aureus was found to persist in an 85-year-old woman 75 years after the successful treatment of osteomyelitis during her childhood.
- Free Full Text
According to Rachet, Küssmaul in 1868 was the first to practice gastroscopy, the subject of his experiment having been a professional sword-swallower. In 1933, a Wolf-Schindler flexible gastroscope was used in 75 patients without ill effect in any way, and was helpful in gastritis, gastric ulcer, and benign and malignant tumors of the stomach.
Featured Multimedia
Showing 1 to 20 of 581 Articles
Filter Results
- By Topic
- All Topics
- Surgery General (324)
- Cardiovascular Surgery (296)
- By Article Category
- All Categories
- Research (163)
- Clinical Cases (135)
- Commentary (97)
- Other (69)
- Review (64)
- Perspective (53)
- By Date
- Past 10 years
- Past 20 years
- Past 50 years
- Past 100 years
- Complete archive (1812-present)
- Specific date range
Sort By:
- Newest
- Oldest
- Most Viewed
- Most Cited
Original Article
Ulipristal Acetate versus Placebo for Fibroid Treatment before Surgery
Uterine leiomyomas, or fibroids, are benign, hormone-sensitive, smooth-muscle tumors that occur in 20 to 40% of women of reproductive age. The most common symptoms are menorrhagia and iron-deficiency anemia, which may lead to chronic fatigue that may not be adequately controlled with iron…
Editorial
Uterine Fibroids and Evidence-Based Medicine — Not an Oxymoron
The 2011 report from the Agency for Healthcare Research and Quality on comparative management of uterine fibroids noted, "Despite the prevalence and possible complications of uterine fibroids, few published studies examining the effectiveness of treatment strategies exist." Few therapies are…
Correspondence
Staphylococcus aureus Reactivation Osteomyelitis after 75 Years
To the Editor: In 1934, a 10-year-old girl was hospitalized at the Children's Hospital of Boston for 1 1/2 years for Staphylococcus aureus osteomyelitis of the left femur. This was the preantibiotic era, so she did not receive any antibiotic therapy at that time but, instead, underwent multiple…
- Free Full Text
Original Article
Ulipristal Acetate versus Leuprolide Acetate for Uterine Fibroids
Uterine leiomyomas, or fibroids, are the most common benign uterine tumors in women of reproductive age. In addition to anemia caused by heavy bleeding, fibroids can cause pelvic pain, pressure, dysmenorrhea, reduced quality of life, and infertility. Current management strategies consist mainly of…
- CME
Correspondence
Sildenafil for Severe Lymphatic Malformations
To the Editor: Lymphatic malformations are uncommon congenital vascular anomalies that can cause complications including obstruction of vital organs and their function, recurrent infection, and disfigurement. Current procedural treatments are only partially successful, and lymphatic malformations…
- Free Full Text
Case Records of the Massachusetts General Hospital
Case 3-2012 — A Newborn Boy with Vomiting, Diarrhea, and Abdominal Distention
Presentation of Case. Dr. Rebecca C. Bell (Pediatrics): A 6-day-old boy was admitted to this hospital because of vomiting, diarrhea, and abdominal distention. The patient was born at another hospital to a teenaged primigravida by vaginal delivery after a full-term, uncomplicated gestation. The…
Case Records of the Massachusetts General Hospital
Case 2-2012 — A 63-Year-Old Woman with Dyspnea and Rapidly Progressive Respiratory Failure
Presentation of Case. Dr. Susan K. Mathai (Internal Medicine): A 63-year-old woman was admitted to this hospital because of rapidly progressive respiratory failure. The patient had a history of Poland syndrome (agenesis of the right breast, pectoralis muscle, and the third and fourth costal…
A 63-year-old woman was admitted to the hospital because of respiratory failure. She had a history of granulomatous polyangiitis and a breast implant that had recently become painful. Imaging revealed bilateral pulmonary infiltrates and a soft-tissue mass extending from the implant through the chest wall.
Review Article
Current Concepts: Cognitive and Neurologic Outcomes after Coronary-Artery Bypass Surgery
Patients referred for coronary revascularization procedures are older and are likely to have more extensive extracardiac vascular disease than those referred for such procedures in the past. Despite these trends, mortality rates for coronary-artery bypass grafting (CABG), without concurrent…
- CME
Correspondence
Factor XIII in the Treatment of Hemophilia A
To the Editor: Patients with hemophilia A (a deficiency of factor VIII [FVIII]) have spontaneous bleeding because of abnormal thrombin generation, which results in the formation of weak, unstable clots. The formation of these weak clots is also the result of delayed and reduced activation of…
- Free Full Text
Images in Clinical Medicine
Jugular Venous C-V Wave in Severe Tricuspid Regurgitation
Figure 1.
- Free Full Text
- Video
Correspondence
Acute Coronary Thrombosis in Boston Marathon Runners
To the Editor: Regular exercise reduces the incidence of coronary atherosclerotic disease and decreases mortality after myocardial infarction, but vigorous activity increases the risk of myocardial infarction and sudden death among patients with occult and diagnosed coronary artery disease. We…
- Free Full Text
Clinical Practice
Hidradenitis Suppurativa
Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations. Stage. A 36-year-old…
- CME
Images in Clinical Medicine
Lung Herniation after Cough-Induced Rupture of Intercostal Muscle
Figure 1.
- Free Full Text
Perspective
Timeline: 200 Years of the New England Journal of Medicine
This interactive timeline represents all the research and review articles and case reports published in the New England Journal of Medicine from 1812 to 2012. The expanding navigation panel at the top of the timeline is an overview of the 200 years, with articles color-coded by medical specialty.…
- Free Full Text
- Interactive/Multimedia
Review Article
200th Anniversary Article: A Tale of Coronary Artery Disease and Myocardial Infarction
The remarkable facts, that the paroxysm, or indeed the disease itself, is excited more especially upon walking up hill, and after a meal; that thus excited, it is accompanied with a sensation, which threatens instant death if the motion is persisted in; and, that on stopping, the distress…
- Free Full Text








