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Viewing 1 - 20 of 839 Full Text results for search help.html |
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Carapetis JR
…topic in the Journal. A PubMed search for articles on rheumatic fever published between 1967 and 1976 returned 55 New England Journal of Medicine articles — fewer than for endocarditis (77) but more than for stroke and syphilis (24 entries each). A similar PubMed search for the decade 1997 through 2006…
N Engl J Med 357:439, August 2, 2007 Perspective
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Markel H
…doing is testing immune concepts. “I am an empiricist,” says Nabel. “I will look for any kind of protection we can get. In the end, we are searching to identify the critical immune parameters that will predict success in protecting against infection or disease. We need to define both variables…
N Engl J Med 353:753, August 25, 2005 Perspective
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Kronick R
Twenty-five years after the introduction of health maintenance organizations (HMOs) as an alternative to fee-for-service Medicare, the promise of these private plans — that competition among them would lead to improvements in the quality and efficiency of health care delivery — remains largely…
N Engl J Med 360:2048, May 14, 2009 Perspective
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Lyles KW, Colon-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C, Hyldstrup L, Recknor C, Nordsletten L, Moore KA, Lavecchia C, Zhang J, Mesenbrink P, Hodgson PK, Abrams K, Orloff JJ, Horowitz Z, Eriksen EF, Boonen S
…specific case-finding effort was made, no cases of osteonecrosis of the jaw were reported or confirmed by the central adjudication committee after a search of the database. The incidence of delayed union of the qualifying hip fracture was 34 (3.2%) in the zoledronic acid group and 29 (2.7%) in the placebo…
N Engl J Med 357:1799, November 1, 2007 Original Article
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Laver WG
…dangerous human pathogens did not exist in 1951. (Figure) In 1992, Kirsty Duncan, a geographer then at the University of Windsor in Canada, began to search for other victims of the 1918 flu whose bodies had been buried and preserved in permafrost. Eventually she located the bodies of seven young coal miners…
N Engl J Med 350:523, January 29, 2004 Book Review
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Cohn F
…. For this reader, the proper questions and answers lie deeper. In the end, the dichotomy that Putnam establishes with her title remains, and the search for heroic compassion seems only to have begun.
N Engl J Med 349:2278, December 4, 2003 Book Review
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Sweeney MO, Bank AJ, Nsah E, Koullick M, Zeng QC, Hettrick D, Sheldon T, Lamas GA,
…stimulation would lead to a lower risk of persistent atrial fibrillation than would conventional dual-chamber pacing. Methods Study Organization The Search AV Extension and Managed Ventricular Pacing for Promoting Atrioventricular Conduction (SAVE PACe) trial was a randomized, controlled clinical trial…
N Engl J Med 357:1000, September 6, 2007 Original Article
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Lee TH
…, too, should go down this road. Those who examine it closely will quickly discover that the program is less about cardiac surgery than about the search for an alternative to traditional fee-for-service care. The basic concept is far from radical. The seven cardiac surgeons in the Geisinger delivery…
N Engl J Med 357:531, August 9, 2007 Perspective
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Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, Barrett JH, Konig IR, Stevens SE, Szymczak S, Tregouet DA, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H
…coronary artery disease to a similar extent in women and in men (Table 5 in the Supplementary Appendix). Candidate-Gene Analysis From a literature search, we identified 142 SNPs, in 91 candidate genes, that had been reported to be associated with coronary artery disease or myocardial infarction. Only…
N Engl J Med 357:443, August 2, 2007 Original Article
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…assessment of the balance between efficacy and safety. The ongoing Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH), a randomized trial involving 12,064 participants with prior myocardial infarction, aims to determine whether a daily dose of 80 mg of simvastatin…
N Engl J Med 359:789, August 21, 2008 Original Article
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Steinbrook R
…Google Scholar, which specifically searches the scholarly literature; and Yahoo, the search engine of the Sunnyvale, California, company of the same name. These search engines are available to anyone who has an Internet connection; none require registration, and searching is free of charge. The rapid changes…
N Engl J Med 354:4, January 5, 2006 Perspective
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Edwards KM, Modjarrad K
In recent years, the public has been increasingly concerned about adverse events that have been attributed to vaccines. Although such safety concerns have existed since the days of Edward Jenner, modern-day opponents of vaccines are waging a particularly aggressive and personal campaign against…
N Engl J Med 360:1159, March 12, 2009 Book Review
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Chambers DA
In his largely autobiographical book, In Search of Memory, Nobel laureate Eric Kandel takes us, in a tour de force, on the two complementary voyages — one private, one professional — that have encompassed his life. Kandel elucidates the transformation of psychiatry from the dominant Freudian-based…
N Engl J Med 355:1745, October 19, 2006 Book Review
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Merson M
…infected during the trials; and the limited interest among industrialized countries in supporting vaccine research. Cohen argues that this wayward search for an AIDS vaccine could have been avoided through the centralization of leadership and the unification of direction from the outset, along the lines…
N Engl J Med 344:1801, June 7, 2001 Book Review
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Rowland LP
…competitors who sought mutations in the gene for the amyloid precursor protein on chromosome 21. Tanzi describes the tedium and long hours of fruitless searching as well as the joy when a linkage was found. He explains the methods he and his colleagues used and provides simple figures to explain how the mutant…
N Engl J Med 344:1101, April 5, 2001 Book Review
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Yamada T
The recent failure of another potential vaccine against human immunodeficiency virus (HIV) underscores the enormous challenges of tackling diseases whose heaviest burden falls on the developing world. A quarter of a century after the first report of AIDS, our knowledge about how an HIV vaccine…
N Engl J Med 358:1324, March 27, 2008 Perspective
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Ishikawa H
Although more than 100 biographies of Hideyo Noguchi (1876-1928) have been published in Japanese, this book is the first one to be translated into English. As a Japanese microbiologist and immunologist, I think that Peter Durfee has produced an excellent translation of this chronicle of Noguchi's…
N Engl J Med 353:2091, November 10, 2005 Book Review
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Malloy MH
The sudden infant death syndrome (SIDS) was initially defined in 1969 with the goal of identifying infants who had similar characteristics before sudden death so that a common underlying mechanism of death might be discovered. The original definition was quite broad, and its development was driven…
N Engl J Med 351:957, September 2, 2004 Perspective
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Rabbani GH
…with massive diarrhea. Thus, an oral rehydration solution with the ability to reduce the amount of diarrhea would be an important advance in the search for an improved treatment. 7 However, routinely adding a resistant starch to oral rehydration solution may be premature. The physiologic principles…
N Engl J Med 342:345, February 3, 2000 Editorial
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Hayward RA
In this issue of the Journal, Landon and colleagues report on a Herculean undertaking — a study of quality-improvement interventions conducted at 44 community health centers. 1 This study showed a modest improvement in some process measures and no improvement in intermediate or end-stage outcomes…
N Engl J Med 356:951, March 1, 2007 Editorial
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