Closed for Comments
as of March 4, 2009
Thomas H. Lee, M.D., L. David Hillis, M.D., and Elizabeth G. Nabel, M.D.
In the international SYNTAX trial, 1800 patients with three-vessel or left main coronary artery disease were randomly assigned to either revascularization with coronary-artery bypass grafting (CABG) or percutaneous coronary intervention involving drug-eluting stents. The need for repeat revascularization was significantly lower with CABG, but the risk of stroke was significantly higher — a tradeoff that must be considered in making clinical decisions regarding patients with advanced coronary disease. In a roundtable discussion moderated by Dr. Thomas Lee, cardiologists David Hillis and Elizabeth Nabel debate the implications of these findings for clinical practice.
Comments from readers were accepted through March 4, 2009.
