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Viewing 1 - 20 of 1657 Full Text results for nejm |
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Clark TW, Pareek M, Hoschler K, Dillon H, Nicholson KG, Groth N, Stephenson I
…and provided written informed consent. (For eligibility criteria, see the Supplementary Appendix, available with the full text of this article at NEJM.org.) The first 100 subjects enrolled were randomly assigned, in a 1:1:1:1 ratio (in five blocks of 20 subjects), to receive two doses of 7.5 μg of…
N Engl J Med; published at www.nejm.org on September 10, 2009 (10.1056/NEJMoa0907650). Original Article
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…as the Fluid and Catheter Treatment Trial (FACTT), can be found in the Supplementary Appendix, available with the full text of this article at www.nejm.org. Patients who had had acute lung injury for 48 hours or less were randomly assigned in permuted blocks of eight to receive a PAC or a CVC with the…
N Engl J Med 354:2213, May 25, 2006 Original Article
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de Berker D
…most of the rest. Many of these are found in soil or plant material (see the Supplementary Appendix, available with the full text of this article at NEJM.org). Most commonly, fungus invades the nail and nail bed by penetrating the distal or lateral margins (distolateral subungual onychomycosis). In other…
N Engl J Med 360:2108, May 14, 2009 Clinical Practice
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Lieberman DA
…adverse events is 3 to 5 events per 1000 colonoscopies (see the Table in the Supplementary Appendix, available with the full text of this article at NEJM.org). Few studies have been performed in diverse practice settings or have followed patients for 30 days to capture all hospitalizations and serious…
N Engl J Med 361:1179, September 17, 2009 Clinical Practice
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Duckworth W, Abraira C, Moritz T, Reda D, Emanuele N, Reaven PD, Zieve FJ, Marks J, Davis SN, Hayward R, Warren SR, Goldman S, McCarren M, Vitek ME, Henderson WG, Huang GD
…primary and secondary outcomes (Appendix 1 and Appendix 2, respectively, in the Supplementary Appendix, available with the full text of this article at NEJM.org). There was no significant difference in the time to death from cardiovascular causes (P=0.26) ( Figure 3B). No significant differences in the rate…
N Engl J Med 360:129, January 8, 2009 Original Article
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Marchbanks PA, McDonald JA, Wilson HG, Folger SG, Mandel MG, Daling JR, Bernstein L, Malone KE, Ursin G, Strom BL, Norman SA, Wingo PA, Burkman RT, Berlin JA, Simon MS, Spirtas R, Weiss LK
…models. For modeling, factors were categorized as shown in Supplementary Appendix 1 (available with the complete text of this article at http://www.nejm.org). Tests for linear trend were conducted with models containing the relevant ordinal categorical variable and an indicator variable for contraceptive…
N Engl J Med 346:2025, June 27, 2002 Original Article
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Yusuf S, Diener HC, Sacco RL, Cotton D, Ounpuu S, Lawton WA, Palesch Y, Martin RH, Albers GW, Bath P, Bornstein N, Chan BPL, Chen ST, Cunha L, Dahlof B, De Keyser J, Donnan GA, Estol C, Gorelick P, Gu V, Hermansson K, Hilbrich L, Kaste M, Lu C, Machnig T, Pais P, Roberts R, Skvortsova V, Teal P, Toni D, VanderMaelen C, Voigt T, Weber M, Yoon BW
…arterial disease, and stroke before qualifying event (for details, see the Supplementary Appendix, available with the full text of this article at www.nejm.org). Results Patients From September 11, 2003, to July 14, 2006, a total of 20,332 patients were enrolled in the trial. Of these patients, 10,146 were…
N Engl J Med 359:1225, September 18, 2008 Original Article
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Hammond SP, Baden LR
…students or physicians in training (15%), other healthcare professionals (15%), or other (4%). Detailed results are displayed according to country at www.nejm.org. The percentage of participants who selected a given treatment option varied substantially when the responses were stratified according to the participants'…
N Engl J Med 359:e20, October 9, 2008 Clinical Decisions
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Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HAW
…the conventional-therapy group (P<0.04) (Figure 1 and Figure 2 in the Supplementary Appendix, available with the full text of this article at www.nejm.org). Clinical Outcomes In the sulfonylurea-insulin group as compared with the conventional-therapy group, significant reductions in relative risk that…
N Engl J Med 359:1577, October 9, 2008 Original Article
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Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, Camargo A, Gupta S, Moore J, Wrobel MJ, Lerner J, Reich M, Chan JA, Glickman JN, Ikeda K, Hashimoto M, Watanabe G, Daidone MG, Roayaie S, Schwartz M, Thung S, Salvesen HB, Gabriel S, Mazzaferro V, Bruix J, Friedman SL, Kumada H, Llovet JM, Golub TR
…adjacent liver tissue, and subjected to RNA extraction as described in the Supplementary Appendix (available with the full text of this article at www.nejm.org). Analysis of Gene Expression Gene-expression profiling was performed according to the complementary DNA-mediated annealing, selection, extension…
N Engl J Med 359:1995, November 6, 2008 Original Article
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…criteria have also been described previously 14 (for details, see the Supplementary Appendix, available with the full text of this article at www.nejm.org). The primary objectives of our study were to determine the effectiveness of 80 mg of telmisartan daily, as compared with 10 mg of ramipril daily…
N Engl J Med 358:1547, April 10, 2008 Original Article
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…eligibility criteria have been published previously 11 and are provided in the Supplementary Appendix (available with the full text of this article at www.nejm.org). Study Intervention Patients were randomly assigned to receive a combined pill containing 2.5 mg of folic acid, 50 mg of vitamin B 6, and 1 mg…
N Engl J Med 354:1567, April 13, 2006 Original Article
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…described previously, 21 and the complete study protocol is available in the Supplementary Appendix (available with the full text of this article at www.nejm.org). The study was approved by the Human Rights Committee at the West Haven VA Cooperative Studies Program (CSP) Coordinating Center and by the institutional…
N Engl J Med 359:7, July 3, 2008 Original Article
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Holman RR, Paul SK, Bethel MA, Neil HAW, Matthews DR
…and glycated hemoglobin at year 4 (P=0.04 for both end points) (see the Supplementary Appendix, available with the full text of this article at www.nejm.org). Clinical Outcomes Among patients undergoing tight blood-pressure control as compared with those undergoing less-tight control, significant relative…
N Engl J Med 359:1565, October 9, 2008 Original Article
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…drafted this report on behalf of the SEARCH Collaborative Group (see the Supplementary Appendix, available with the full text of this article at www.nejm.org) and take responsibility for the completeness, accuracy, and integrity of the data. Genotyping and Sequencing in Search The genomewide association…
N Engl J Med 359:789, August 21, 2008 Original Article
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Residentsâ Duty Hours and the IOM Report Closed for Comments as of December 24, 2008 John K. Iglehart In 2003, the Accreditation Council of Graduate Medical Education (ACGME) placed national limits on the duty hours of medical residents in the United States. In a Perspective article, John…
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Halperin F, Ingelfinger JR, McMahon GT
…physicians-in-training (17%), other health professionals (12%), or other (4%). Detailed results are displayed according to country and specialty at www.nejm.org. The percentage of participants who selected a given treatment varied substantially when the responses were stratified according to the participants'…
N Engl J Med 358:e8, February 14, 2008 Clinical Decisions
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…Study Design The complete protocol for this trial can be found in the Supplementary Appendix (available with the full text of this article at www.nejm.org). Patients were randomly assigned to a strategy involving either conservative or liberal use of fluids with concealed allocation in permuted blocks…
N Engl J Med 354:2564, June 15, 2006 Original Article
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Comparison of Weight-Loss Diets Closed for Comments as of March 11, 2009 On February 25, 2009, we published an article and an accompanying editorial on a randomized trial comparing the effects of reduced-calorie diets with various compositions of fat, carbohydrates, and protein on weight loss over…
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Curfman GD, Morrissey S, Annas GJ, Drazen JM
…confidentiality of the peer-review process is a very significant one, especially in light of its non-party status, and tips the scales in favor of the NEJM.” The case could have ended there, but the judge went on to determine that as a matter of public policy editors and peer reviewers are entitled to…
N Engl J Med 358:2276, May 22, 2008 Editorial
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