Browse Toxicology

Showing 1 to 20 of 31 Articles

Filter Results

By Date: Past 10 years; Past 20 years; Past 50 years; Past 100 years; Complete archive (1812-present); Specific date range

Show Only Articles with CME

Sort By:

Case Records of the Massachusetts General Hospital
Case 7-2012 — A 79-Year-Old Man with Pain and Weakness in the Legs
Presentation of Case. Dr. Aida E. Kuri (Medicine): A 79-year-old man was admitted to this hospital because of pain and weakness in the legs. The patient had multiple medical problems but had been in his usual state of health until 6 days before admission, when progressive, generalized pain and…
- March 8, 2012
- David W.S., Chad D.A., Kambadakone A., Hedley-Whyte E.T.
- N Engl J Med 2012; 366:944-954
- CME
- Video
A 79-year-old man was admitted to the hospital because of pain and weakness in the legs. He had multiple chronic medical problems and took numerous medications, with no recent changes. Examination revealed leg weakness and decreased reflexes.
- PDF
- Save
Case Records of the Massachusetts General Hospital
Case 6-2012 — A 45-Year-Old Man with a History of Alcohol Abuse and Rapid Cognitive Decline
Presentation of Case. Dr. Clayton Knox (Medicine): A 45-year-old man with a history of alcoholism was admitted to this hospital because of rapid cognitive decline and worsening jaundice. During the previous 3 months, increasing fatigue and cough productive of yellow sputum and flecks of blood had…
- February 23, 2012
- Cho T.A., Larvie M., Tian D., Mino-Kenudson M.
- N Engl J Med 2012; 366:745-755
- CME
A 45-year-old man with a history of alcoholism was admitted to the hospital because of cognitive decline and jaundice. He had a 3-month history of cough, blood-tinged sputum, and vomiting. Imaging showed a peripherally enhancing brain lesion. A diagnostic procedure was performed.
- PDF
- Save
Review Article
Current Concepts: The Autosomal Recessive Cerebellar Ataxias
The autosomal recessive cerebellar ataxias are a group of little known and often neglected diseases that are best understood by following a practical, multidisciplinary approach that focuses on clinical rather than molecular considerations. This review focuses on the main forms in which cerebellar…
- February 16, 2012
- Anheim M., Tranchant C., Koenig M.
- N Engl J Med 2012; 366:636-646
- CME
- Video
Autosomal recessive cerebellar ataxia must be considered in any child or young adult with a progressive disorder of gait or balance or with hypotonia or excessive clumsiness. This review presents a practical approach to these neurodegenerative diseases.
- PDF
- Save
Special Article
Emergency Hospitalizations for Adverse Drug Events in Older Americans
Decreasing the number of preventable rehospitalizations by 20% by the end of 2013 is a goal of the $1 billion federal initiative Partnership for Patients, and the pursuit of this goal represents an opportunity to reduce harm to patients and reduce health care costs. Adverse drug events are a direct…
- November 24, 2011
- Budnitz D.S., Lovegrove M.C., Shehab N., Richards C.L.
- N Engl J Med 2011; 365:2002-2012
- Free Full Text
This national study estimated that nearly 100,000 elderly patients were hospitalized for adverse drug events annually from 2007 through 2009. Most resulted from use of common medications such as warfarin and insulin, and only 1% from medications designated as high-risk.
- PDF
- Save
Perspective
Drunk Driving, Distracted Driving, Moralism, and Public Health
In 1980, Candy Lightner gave a speech about a 13-year-old girl who was killed by a drunk driver with several previous arrests for driving while intoxicated (DWI). She ended by saying, "That little girl was my daughter." "The audience gasped," Lightner later reported. "The press jumped up and ran…
- September 8, 2011
- Lerner B.H.
- N Engl J Med 2011; 365:879-881
- Free Full Text
Can we blend the moral passion of anti–drunk-driving activism with epidemiologically based strategies for saving lives on the roads? The history of efforts to prevent automobile crashes offers lessons on various approaches and their possible synergy.
- PDF
- Save
Correspondence
“Bath Salts” Intoxication
To the Editor: The abuse of psychoactive "bath salts" (PABS) has become commonplace, and patients with PABS overdoses are presenting to emergency departments with increasing frequency. The primary ingredient of the synthetic designer drugs in these bath salts, which are not related to any hygiene…
- September 8, 2011
- N Engl J Med 2011; 365:967-968
- Free Full Text
This letter highlights recreational ingestion of bath salts containing methylenedioxypyrovalerone, a potent central nervous system stimulant. Intoxication that results in extreme sympathetic stimulation and profoundly alters mental status may be fatal.
- PDF
- Save
Images in Clinical Medicine
Evolution of a Jellyfish Sting
Figure 1.
- July 21, 2011
- Avelino-Silva V.I. and Avelino-Silva T.
- N Engl J Med 2011; 365:251
- Free Full Text
A healthy 33-year-old woman was stung by a jellyfish on the medial aspect of her left ankle while wading in the coastal waters of North Carolina. Within hours, painful, erythematous, linear, urticarial lesions developed where the jellyfish tentacles had made contact with her skin.
- PDF
- Save
Images in Clinical Medicine
Angioedema
Figure 1.
- July 14, 2011
- Bramante R.M. and Rand M.
- N Engl J Med 2011; 365:e4
- Free Full Text
A 71-year-old man presented to the ER with rapidly progressive tongue swelling. Examination revealed a swollen tongue and no hypotension, rash, bronchospasm, urticaria, or flushing. The patient had no recent exposures to known food allergens, new medications, or insect stings.
- PDF
- Save
Images in Clinical Medicine
Toxic Effects of Levamisole in a Cocaine User
Figure 1.
- June 16, 2011
- Muirhead T.T. and Eide M.J.
- N Engl J Med 2011; 364:e52
- Free Full Text
A 54-year-old woman presented with a 2-day history of a painful, enlarging rash over her face (Panel A), ears (Panel B), breasts, and extremities. Laboratory studies revealed neutropenia (neutrophil count, 1070 per cubic millimeter) and lymphopenia (...
- PDF
- Save
Review Article
Current Concepts: The Gulf Oil Spill
One year after the Gulf oil spill (also known as the Deepwater Horizon oil spill, the BP oil spill, or the Gulf of Mexico oil spill), the full magnitude of the environmental, economic, and human health effects of this major disaster remain unknown. Despite a growing literature describing the impact…
- April 7, 2011
- Goldstein B.D., Osofsky H.J., Lichtveld M.Y.
- N Engl J Med 2011; 364:1334-1348
- Free Full Text
The 2010 Gulf Oil spill was an occupational, environmental, and community health disaster. This review summarizes the contaminants of concern, toxicologic consequences for humans and the ecosystem, lessons for worker safety, and mental health consequences in the community.
- PDF
- Save
Case Records of the Massachusetts General Hospital
Case 9-2011 — A 37-Year-Old Man with Flushing and Hypotension
Presentation of Case. Dr. Leana S. Wen (Emergency Medicine): A 37-year-old man was admitted to the hospital because of flushing and hypotension. That morning, sneezing, rhinorrhea, scratchy throat, and subjective fever had developed. After lunch, he took an over-the-counter cold preparation that…
- March 24, 2011
- Murali M.R., Castells M.C., Song J.Y., Dudzinski D.M., Hasserjian R.P.
- N Engl J Med 2011; 364:1155-1165
- CME
- Video
A 37-year-old man was admitted to the hospital because of flushing and hypotension with near-syncope. Similar episodes had occurred with increasing frequency during the past 12 years. A test result was received.
- PDF
- Save
Images in Clinical Medicine
Opsoclonus Due to Diphenhydramine Poisoning
Figure 1.
- December 30, 2010
- Carstairs S.D. and Schneir A.B.
- N Engl J Med 2010; 363:e40
- Free Full Text
- Video
A 20-year-old woman was evaluated at the hospital 2 hours after ingesting 5 g of diphenhydramine in a suicide attempt. She had a generalized seizure en route to the hospital and several more in the emergency department. Electrocardiography revealed sinus ...
- PDF
- Save
Original Article
Neonatal Abstinence Syndrome after Methadone or Buprenorphine Exposure
Opioid dependence during pregnancy is compounded by multiple risk factors contributing to adverse maternal, neonatal, and long-term developmental consequences.– Improved treatment options should reduce the public health and medical costs associated with the treatment of neonates exposed to…
- December 9, 2010
- Jones H.E., Kaltenbach K., Heil S.H., et al.
- N Engl J Med 2010; 363:2320-2331
- Free Full Text
In this trial comparing methadone with buprenorphine in opioid-dependent pregnant women, neonates exposed to buprenorphine required less morphine to treat neonatal abstinence syndrome (NAS) and had a significantly shorter duration of hospitalization and of treatment for NAS.
- PDF
- Save
Perspective
A Flood of Opioids, a Rising Tide of Deaths
Faced with an epidemic of drug abuse and overdose deaths involving prescription opioid pain relievers, the Food and Drug Administration (FDA) plans to require opioid makers to provide training for physicians and patient-education materials on the appropriate prescribing and use of extended-release…
- November 18, 2010
- Okie S.
- N Engl J Med 2010; 363:1981-1985
- Free Full Text
Faced with an epidemic of drug abuse and overdose deaths, the FDA has proposed a Risk Evaluation and Mitigation Strategy for prescription opioid pain relievers, involving improved education for physicians and patients about risks associated with long-acting opioids.
- PDF
- Save
Correspondence
Poppers-Associated Retinal Toxicity
To the Editor: "Poppers" (slang for various forms of alkyl nitrite) are volatile nitric oxide donors that have been used for decades as recreational drugs. Both the popularity of and legal tolerance for poppers have led to the perception that these drugs are relatively innocuous. Here, we describe…
- October 14, 2010
- N Engl J Med 2010; 363:1583-1585
- Free Full Text
To the Editor: “Poppers” (slang for various forms of alkyl nitrite) are volatile nitric oxide donors that have been used for decades as recreational drugs. Both the popularity of and legal tolerance for poppers have led to the perception that these drugs ...
- PDF
- Save
Images in Clinical Medicine
Rattlesnake Envenomation
Figure 1.
- June 10, 2010
- Levine M. and Ruha A.-M.
- N Engl J Med 2010; 362:2212
- Free Full Text
A 59-year-old man presented within 30 minutes after having been bitten in the index finger by a rattlesnake. Hemorrhagic bullae developed on the right index finger at the site of the snakebite.
- PDF
- Save
Correspondence
Myxedema Coma Induced by Ingestion of Raw Bok Choy
To the Editor: An 88-year-old Chinese woman was brought to the emergency department by her family, who reported that she had been lethargic and unable to walk or swallow for 3 days. She had been eating an estimated 1.0 to 1.5 kg of raw bok choy daily for several months in the belief that it would…
- May 20, 2010
- N Engl J Med 2010; 362:1945-1946
- Free Full Text
To the Editor: An 88-year-old Chinese woman was brought to the emergency department by her family, who reported that she had been lethargic and unable to walk or swallow for 3 days. She had been eating an estimated 1.0 to 1.5 kg of raw bok choy daily for ...
- PDF
- Save
Correspondence
Severe, Acute Liver Injury and Khat Leaves
To the Editor: The chewing of khat leaves (Catha edulis) is a widespread recreational custom in East Africa and the Arabian Peninsula. The plant contains the alkaloids cathine and cathinone, which have amphetamine-like properties and produce a variety of pleasurable effects. Khat is banned in the…
- April 29, 2010
- N Engl J Med 2010; 362:1642-1644
- Free Full Text
To the Editor: The chewing of khat leaves (Catha edulis) is a widespread recreational custom in East Africa and the Arabian Peninsula. The plant contains the alkaloids cathine and cathinone, which have amphetamine-like properties and produce a variety of ...
- PDF
- Save
Case Records of the Massachusetts General Hospital
Case 12-2010 — An 89-Year-Old Man with Progressive Dyspnea
Presentation of Case. An 89-year-old man was admitted to the hospital because of progressive dyspnea. The patient had been in his usual state of health, with diabetes mellitus, coronary artery disease, and complete heart block, until 6 months before admission, when shortness of breath developed.…
- April 22, 2010
- Kradin R.L., Digumarthy S.R., Baggish A.L., Mark E.J.
- N Engl J Med 2010; 362:1522-1531
- Video
An 89-year-old man was admitted to the hospital because of progressive dyspnea for 6 months, worsening over the past 3 days. He had a history of exposure to asbestos and had smoked cigarettes for many years. Imaging studies revealed a pleural plaque and pulmonary interstitial fibrosis with superimposed ground-glass opacities. Hypoxemia and intermittent hypotension occurred. Despite oxygen supplementation, mechanical ventilation, and pressor administration, a cardiac arrest occurred, and the patient died on the eighth hospital day. An autopsy was performed.
- PDF
- Save
Original Article
Lung Function in Rescue Workers at the World Trade Center after 7 Years
The terrorist attack on the world Trade Center on September 11, 2001 (hereafter referred to as 9/11), and its consequent collapse killed 2751 persons, including 343 rescue workers employed by the Fire Department of New York City (FDNY) and exposed thousands of persons to a dense, persistent dust…
- April 8, 2010
- Aldrich T.K., Gustave J., Hall C.B., et al.
- N Engl J Med 2010; 362:1263-1272
- Free Full Text
Lung function was measured in firefighters and emergency-medical-service workers who responded to the collapse of the World Trade Center towers in New York on September 11, 2001. There was initial marked loss in lung-function measures without substantial recovery during the following 7 years.
- PDF
- Save

Page

Medical Meetings Pediatrics Conferences and Meetings

2012 Certifying Examinations of the American Board of Pediatrics

The general pediatrics examination will be held in various cities, Oct. 16-18. Registration for first-time applicants is ongoing through May 3. Registration for re-registrants is ongoing through May 24. The following subspecialty examinations will be held in various cities: "Hospice and Palliative Medicine" (Oct. 4); "Pediatric Transplant Hepatology" (Oct. 11); "Pediatric Cardiology" (Nov. 7); "Pediatric Pulmonology" (Nov. 8); "Medical Toxicology" (Nov. 12); and "Pediatric Critical Care Medicine" (Nov. 14). Registration for first-time applicants is ongoing through April 30. Registration for re-registrants is ongoing through June 15.

Contact the American Board of Pediatrics, 111 Silver Cedar Court, Chapel Hill, NC 27514-1513; or call (919) 929-0461; or fax (919) 918-7114 or (919) 929-9255; or see http://www.abp.org .

More Medical Meetings

Trends: Most Viewed (Last Week)

More Trends