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Perspective
The Joint Commission's New Tobacco-Cessation Measures — Will Hospitals Do the Right Thing?
Few factors influence health care standards in the United States today more than the actions of the Joint Commission (formerly the Joint Commission on Accreditation of Healthcare Organizations). And few opportunities hold more promise for increasing the rate of tobacco-use cessation than patient…
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Perspective
Tropical Lymphedemas — Control and Prevention
There are two principal causes of elephantiasis, or lymphedema, in the tropics. The most common cause and a significant public health problem is lymphatic filariasis due to the parasitic nematode Wuchereria bancrofti (and, in Asia, Brugia malayi and B. timori), which is transmitted by mosquitoes.…
Case Records of the Massachusetts General Hospital
Case 8-2012 — A 53-Year-Old Man with Crohn's Disease, Diarrhea, Fever, and Bacteremia
Presentation of Case. Dr. Jacob Soumerai (Internal Medicine): A 53-year-old man with Crohn's disease who was receiving immunosuppressive therapy was admitted to this hospital because of diarrhea, fever, and bacteremia. The patient had been in his usual state of health until 2 days before admission,…
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Perspective
Protecting Service Members in War — Non-Battle Morbidity and Command Responsibility
On August 31, 2011, a 24-year-old soldier from California died from complications of rabies treatment. He was infected months earlier, from a dog bite he sustained in Afghanistan. His death provides a glimpse of the risk of disease and non-battle injuries that service members face in war. Although…
Perspective
The Emerging Threat of Untreatable Gonococcal Infection
It is time to sound the alarm. During the past 3 years, the wily gonococcus has become less susceptible to our last line of antimicrobial defense, threatening our ability to cure gonorrhea and prevent severe sequelae. Gonorrhea is the second most commonly reported communicable disease in the United…
Perspective
Opportunity in Austerity — A Common Agenda for Medicine and Public Health
Faced with the growing pressure to reduce the federal budget deficit, government leaders have increasingly turned their attention to reducing health expenditures. In this atmosphere of austerity, public health programs are likely to be hit particularly hard as they compete for funds against the…
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Perspective
Improving Childhood Vaccination Rates
Recently, the mother of a young child confessed to me that she didn't know any parents who were following the recommended immunization schedule for their children. She said that when she told her pediatrician she'd like to follow an alternative schedule, the physician had simply acquiesced, leading…
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Perspective
Assessing Supplement Safety — The FDA's Controversial Proposal
Recently, a well-respected dietary-supplement company in Utah announced the recall of Zotrex, a sexual enhancement supplement labeled as containing "Ophioglossum polyphyllous." The problem with Zotrex was twofold: not only is no species of ophioglossum (adder's tongue) an established dietary…
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Perspective
Time for a Change — A New Approach to ICD Replacement
Clinical trials of implantable cardioverter–defibrillators (ICDs) continue to drive expanding indications for these devices. More than 100,000 ICDs are implanted in the United States annually. Of these procedures, at least 25% are generator replacements required as a result of depleted battery…
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Perspective
Painful Inequities — Palliative Care in Developing Countries
When Artur, a former KGB agent in Ukraine, developed prostate cancer that metastasized to his bones, his pain grew so intense that he moved hours away from his family so they would not witness his suffering. "I don't want them to see me cry," he said. Lacking access to the opioid regimens that we…
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Perspective
Alleviating Suffering 101 — Pain Relief in the United States
The magnitude of pain in the United States is astounding. More than 116 million Americans have pain that persists for weeks to years. The total financial costs of this epidemic are $560 billion to $635 billion per year, according to Relieving Pain in America, the recent report of an Institute of…
Perspective
The Politics of Emergency Contraception
On December 7, 2011, Health and Human Services (HHS) Secretary Kathleen Sebelius instructed Food and Drug Administration (FDA) Commissioner Margaret Hamburg not to approve the application for over-the-counter sales of Plan B One-Step, a single-dose emergency contraceptive. Dr. Hamburg issued her…
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Correspondence
Community Transmission of Oseltamivir-Resistant A(H1N1)pdm09 Influenza
To the Editor: Oseltamivir-resistant prepandemic seasonal influenza A (H1N1) viruses with a H275Y neuraminidase substitution spread globally in 2008, reducing the effectiveness of oseltamivir. Although oseltamivir-resistant pandemic 2009 A (H1N1) viruses, now known as A(H1N1)pdm09, have been…
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Perspective
Global Health: Facing a “Slow-Motion Disaster” — The UN Meeting on Noncommunicable Diseases
You might think Linda Ezekiel would always be in a hurry. As the first nephrologist in Tanzania, she started and now runs her country's only public-sector dialysis unit. She is currently spearheading Tanzania's first renal transplantation program. And she manages the postoperative care of 80…
Perspective
Global Health: Stemming the Brain Drain — A WHO Global Code of Practice on International Recruitment of Health Personnel
The World Health Organization (WHO) estimates that the world faces a shortage of 4.3 million health professionals required for delivering essential health care services to populations in need. This shortage constitutes a major barrier to the provision of essential lifesaving health services, such…
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Perspective
Global Health: War, Drought, Malnutrition, Measles — A Report from Somalia
Somalia has been in the grips of disaster for two decades. Throughout this past summer, the human catastrophe dramatically worsened. War and drought have driven hundreds of thousands of people from their homes in south and central Somalia, with some families walking for more than a week across the…
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Perspective
The Role of Cost-Effectiveness in U.S. Vaccination Policy
Vaccination policy is driven by several factors, including vaccine safety and efficacy, avertable disease burden, acceptability, and societal value. One measure of value is an intervention's cost-effectiveness, defined as the additional cost required per additional unit of health benefit produced…
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Perspective
The 2010 Dietary Guidelines — The Best Recipe for Health?
The 2010 U.S. Dietary Guidelines were issued earlier this year, though they received little notice in the press. The lack of attention is troubling in a country in the throes of a nutritional crisis manifested most conspicuously in the form of an obesity epidemic that threatens to reverse recent…
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Perspective
Individual Responsibility or a Policy Solution — Cap and Trade for the U.S. Diet?
Chronic illness accounts for as much as three quarters of the cost of medical care in the United States, and diseases such as obesity, hypertension, and diabetes, although complex in etiology, are at least partially rooted in our unhealthy diet. The routine overconsumption of foods containing large…
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Special Article
Neighborhoods, Obesity, and Diabetes — A Randomized Social Experiment
Many observational studies have shown that neighborhood attributes such as poverty and racial segregation are associated with increased risks of obesity and diabetes, even after adjustment for observed individual and family-related factors.– In response, the U.S. surgeon general has called for…
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