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  • Perspective

    The primary care doctor is a rapidly evolving species — and in the future could become an endangered one. As the United States grapples with the dual challenges of making health care more widely available and reducing the national price tag, it's hard to say how primary care physicians will fit…

    • May 17, 2012
    • Okie S.
    • N Engl J Med 2012; 366:1849-1853
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    • Audio

    The primary care doctor is a rapidly evolving species — and could become an endangered one. As we grapple with making health care more widely available and reducing its cost, it's hard to say how primary care physicians will fit into emerging delivery models.

  • Review Article

    Surgery is a profession defined by its authority to cure by means of bodily invasion. The brutality and risks of opening a living person's body have long been apparent, the benefits only slowly and haltingly worked out. Nonetheless, over the past two centuries, surgery has become radically more…

    • May 3, 2012
    • Gawande A.
    • N Engl J Med 2012; 366:1716-1723
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    • Interactive/Multimedia

    This review article traces the history and progress of surgery over the past two centuries, during which the profession evolved from rapidly performed, rudimentary, and often unsuccessful procedures to bold reconstruction, intricate microsurgery, transplantation, and more.

  • Perspective

    Thirty years ago, an intern had a conversation with a patient that he regrets to this day. The patient, a young man with widely metastatic lymphoma, unresponsive to chemotherapy, now had progressive dyspnea. The intern knew that even with intubation, his patient would soon die. Although the norm at…

    • May 3, 2012
    • Lamas D. and Rosenbaum L.
    • N Engl J Med 2012; 366:1655-1657

      Paternalism in discussing resuscitation status has given way to an approach in which patients may be asked to choose from a bewildering array of medical options, but physicians-in-training are rarely taught how to lead such conversations confidently and effectively.

    • Perspective

      The last substantive reform in medical student education followed the Flexner Report, which was written in 1910. In the ensuing 100 years, the volume of medical knowledge has exploded, the complexity of the health care system has grown, pedagogical methods have evolved, and unprecedented…

      • May 3, 2012
      • Prober C.G. and Heath C.
      • N Engl J Med 2012; 366:1657-1659

        Medical education in this era of a vast medical canon can be improved without increasing the time it takes to earn a medical degree, if we make lessons “stickier” and embrace a learning strategy that is self-paced and mastery-based and that boosts engagement.

      • Perspective

        A 75-year-old man was admitted to the hospital for the third time in 3 months for congestive heart failure. His ejection fraction was 15%, and he was receiving state-of-the-science treatment, including intravenous inotropic agents. He was not a candidate for a heart transplant, but the possibility…

        • May 3, 2012
        • Quill T.E. and Holloway R.G.
        • N Engl J Med 2012; 366:1653-1655
        • Audio

        Much progress has been made in applying scientific evidence to medical practice; less progress has been made in rendering care “patient-centered.” A five-step framework for reconciling the tension between “evidence-based” and “preference-based” medicine may help.

      • Perspective

        Disparate voices from the White House, a national fiscal commission, Congress, a Medicare advisory body, private foundations, and academic medical leaders are advocating changes to Medicare's investment in graduate medical education (GME), which currently totals $9.5 billion annually. They offer…

        • April 26, 2012
        • Iglehart J.K.
        • N Engl J Med 2012; 366:1562-1563
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        Disparate voices are advocating changes to Medicare's investment in graduate medical education (GME) — now $9.5 billion annually. Prescriptions include reducing federal support, developing performance measures, and assessing programs' governance and financing.

      • Perspective

        As Chicago physician J.H. Salisbury remarked in 1906, the influence of the medical journal on the life of the physician is unparalleled: "Medical school is attended, as a rule, but once in a lifetime; the meetings of the medical society are usually infrequent, but the medical journal, like the…

        • April 19, 2012
        • Podolsky S.H., Greene J.A., Jones D.S.
        • N Engl J Med 2012; 366:1457-1461
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        In addition to disseminating new knowledge, medical journals define the scope of medical concerns and articulate norms for physicians' professional and social roles. The history of NEJM provides a window on the changing functions of journals and the medical profession.

      • Interactive Medical Case

        A 38-year-old woman in Florida presented to her primary care physician with shortness of breath, fever, and a cough productive of yellow sputum. She was treated empirically with antibiotics for a presumed respiratory tract infection, and her symptoms resolved. She returned a few weeks later with an…

        • April 12, 2012
        • Vaidya A., Solomon D.A., Fanta C.H.
        • N Engl J Med 2012; 366:e24
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        • CME

        A 38-year-old woman had shortness of breath, fever, and cough with yellow sputum soon after childbirth. Her symptoms initially resolved with antibiotics, but she soon had nonproductive cough, wheeze, and shortness of breath. Test your diagnostic and therapeutic skills at NEJM.org.

      • Review Article

        Sixty-eight years after the inaugural issue of The New England Journal of Medicine and Surgery, Sir William Osler introduced the term "pediatrics." Although "diseases peculiar to children" had figured in Benjamin Rush's lectures at the University of Pennsylvania since 1789, most physicians in the…

        • April 5, 2012
        • Hostetter M.K.
        • N Engl J Med 2012; 366:1328-1334
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        • Interactive/Multimedia

        This article reviews the evolution of child health in four eras — the recognition of children as a specific population (1812–1880), the rise of public health as remedy (1881–1930), the development of vaccines (1931–1980), and the global era (1981–2012).

      • Perspective

        The Medical College Admission Test (MCAT), a prerequisite for admission to U.S. medical schools, currently consists of four sections: physical sciences, verbal reasoning, a writing sample, and biologic sciences. A 2004 Institute of Medicine report on "Improving Medical Education" and several years…

        • April 5, 2012
        • Kaplan R.M., Satterfield J.M., Kington R.S.
        • N Engl J Med 2012; 366:1265-1268
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        • Audio

        Beginning in 2015, the Medical College Admission Test (MCAT) will include sections on behavioral and social sciences and critical analysis and reasoning. These revisions reflect the recognition that behavioral and social factors play major roles in health and illness.

      • Perspective

        In the 1970s and 1980s, industry-sponsored junkets for physicians, thinly disguised as educational events, were common. Increasing public scrutiny and the threat of government regulation and legal action led physicians' organizations and the pharmaceutical industry to adopt increasingly restrictive…

        • March 22, 2012
        • Steinman M.A., Landefeld C.S., Baron R.B.
        • N Engl J Med 2012; 366:1069-1071
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        U.S. medicine may have reached a tipping point in limiting industry involvement in continuing medical education. Progress appears to be accelerating, and further restrictions are likely to become more widespread, thanks to shifting norms in the culture of medicine.

      • Videos in Clinical Medicine

        • March 22, 2012
        • Fitch M.T., Nicks B.A., Pariyadath M., McGinnis H.D., Manthey D.E.
        • N Engl J Med 2012; 366:e17

          The use of emergency pericardiocentesis to aspirate fluid in patients with cardiac tamponade can be a lifesaving procedure that restores normal cardiac function and peripheral perfusion. This video demonstrates the procedure.

        • Perspective

          Rapid advances in medical science and technology, substantial gains in health outcomes attributable to medical care, and budget-busting increases in health care expenditures fueled by private and public insurance have marked the past six decades of health care in the United States. As the country…

          • March 15, 2012
          • Fuchs V.R.
          • N Engl J Med 2012; 366:973-977
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          As the United States struggles to emerge from an economic crisis, policymakers and the public have homed in on skyrocketing health care expenditures. What lessons can be drawn from the evolution, since 1950, in sources of payment and objects of expenditures in health care?

        • Special Report

          In 1999, the Accreditation Council for Graduate Medical Education (ACGME) introduced the six domains of clinical competency to the profession, and in 2009, it began a multiyear process of restructuring its accreditation system to be based on educational outcomes in these competencies. The result of…

          • March 15, 2012
          • Nasca T.J., Philibert I., Brigham T., Flynn T.C.
          • N Engl J Med 2012; 366:1051-1056

            The American Council of Graduate Medical Education is moving from accrediting residency programs every 5 years to a new system for the annual evaluation of trends in measures of performance.

          • Review Article

            People have suffered from asthma for millennia. Although the clinical presentation of asthma has probably changed little, there are many more people who now bear its consequences than there were 200 years ago. As a result of an intense interest in the condition, our understanding of its…

            • March 1, 2012
            • von Mutius E. and Drazen J.M.
            • N Engl J Med 2012; 366:827-834
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            • Interactive/Multimedia

            People have suffered from asthma for millennia. To illustrate the changes in our understanding and treatment of asthma over the past 200 years, the authors provide three fictional reports of consultations performed for essentially the same patient, who has what we now call asthma.

          • Perspective

            The summer before I began medical school, the handyman working in our kitchen told me exactly how many more refrigerators he needed to repair in order to afford his coronary-artery bypass surgery. My excitement about having achieved a lifelong dream was suddenly displaced by doubt. What if the…

            • February 23, 2012
            • Rohrhoff N.J.
            • N Engl J Med 2012; 366:683-685

              A medical student working at health fairs and clinics in underserved communities spends his time asking people what their lives are like — but can't truly empathize until his own father loses his job and his health insurance.

            • Perspective

              The relationship between patients and doctors is at the core of medical ethics, serving as an anchor for many of the most important debates in the field. Over the past several decades, this relationship has evolved along three interrelated axes — as it is defined in clinical care, research, and…

              • February 16, 2012
              • Truog R.D.
              • N Engl J Med 2012; 366:581-585
              • Free Full Text
              • Audio

              The relationship between patients and doctors is at the core of medical ethics, anchoring many important debates in the field. Over the past several decades, this relationship has evolved along three axes — as it is defined in clinical care, research, and society.

            • Interactive Medical Case

              An 89-year-old man presented with changes in cognition and personality. Six months earlier, he began to require help managing his finances and operating his computer. His family observed that he had a poor memory for recent events and found it difficult to express himself. During the next few…

              • February 9, 2012
              • Vaidya A., Dolan B.M., Edlow B.L., Rinne M.L., McGinnis S.M.
              • N Engl J Med 2012; 366:e11
              • Free Full Text
              • CME

              An 89-year-old man was brought to the ER for evaluation of changes in his cognition and personality. He exhibited poor memory for recent events and difficulty expressing himself. Test your diagnostic and therapeutic skills at NEJM.org.

            • Review Article

              Among the many challenges to health, infectious diseases stand out for their ability to have a profound impact on the human species. Great pandemics and local epidemics alike have influenced the course of wars, determined the fates of nations and empires, and affected the progress of civilization,…

              • February 2, 2012
              • Fauci A.S. and Morens D.M.
              • N Engl J Med 2012; 366:454-461
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              • Interactive/Multimedia

              During the past 200 years, our understanding of infectious diseases has radically evolved from the identification of microbes, to defining their genetic structure, to the development of focused antimicrobial therapies, to the realization of vector biology. This article highlights the tremendous advances that have been made in the field.

            • Perspective

              When Artur, a former KGB agent in Ukraine, developed prostate cancer that metastasized to his bones, his pain grew so intense that he moved hours away from his family so they would not witness his suffering. "I don't want them to see me cry," he said. Lacking access to the opioid regimens that we…

              • January 19, 2012
              • Lamas D. and Rosenbaum L.
              • N Engl J Med 2012; 366:199-201
              • Free Full Text

              Whereas effective treatment for noncommunicable diseases may be too costly to disseminate globally, opioids for pain control are cheap to produce. Yet 80% of the population, including millions of patients with terminal cancer, lacks adequate access to pain treatment.

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            Medical Meetings Pediatrics Conferences and Meetings

            2012 Certifying Examinations of the American Board of Pediatrics

            The general pediatrics examination will be held in various cities, Oct. 16-18. Registration for first-time applicants is ongoing through May 3. Registration for re-registrants is ongoing through May 24. The following subspecialty examinations will be held in various cities: "Hospice and Palliative Medicine" (Oct. 4); "Pediatric Transplant Hepatology" (Oct. 11); "Pediatric Cardiology" (Nov. 7); "Pediatric Pulmonology" (Nov. 8); "Medical Toxicology" (Nov. 12); and "Pediatric Critical Care Medicine" (Nov. 14). Registration for first-time applicants is ongoing through April 30. Registration for re-registrants is ongoing through June 15.

            Contact the American Board of Pediatrics, 111 Silver Cedar Court, Chapel Hill, NC 27514-1513; or call (919) 929-0461; or fax (919) 918-7114 or (919) 929-9255; or see http://www.abp.org .

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