Browse Addiction

Showing 1 to 20 of 239 Articles

Filter Results

By Date: Past 10 years; Past 20 years; Past 50 years; Past 100 years; Complete archive (1812-present); Specific date range

Show Only Articles with CME

Sort By:

Original Article
A Randomized Trial of Nicotine-Replacement Therapy Patches in Pregnancy
Smoking in pregnancy is the leading preventable cause of morbidity and death among women and infants. Adverse pregnancy and birth outcomes associated with smoking include placental abruption, miscarriage, prematurity, low birth weight, congenital abnormalities, and neonatal or sudden infant death.…
- March 1, 2012
- Coleman T., Cooper S., Thornton J.G., et al.
- N Engl J Med 2012; 366:808-818
- CME
In this placebo-controlled trial, the addition of a nicotine patch to behavioral support for smoking cessation did not significantly increase rates of prolonged abstinence lasting until delivery, nor did it affect rates of adverse pregnancy and birth outcomes. Compliance rates were low.
- PDF
- Save
Editorial
Nicotine Replacement for Smoking Cessation during Pregnancy
Cigarette smoking during pregnancy increases the risk of delivering a low-birth-weight or preterm infant, as well as the risks of pregnancy complications (premature rupture of membranes and placental abruption) and perinatal and infant death. Despite these risks, 10 to 12% of pregnant women in the…
- March 1, 2012
- Oncken C.
- N Engl J Med 2012; 366:846-847
Cigarette smoking during pregnancy increases the risk of delivering a low-birth-weight or preterm infant, as well as the risks of pregnancy complications (premature rupture of membranes and placental abruption) and perinatal and infant death.¹ Despite ...
- PDF
- Save
Case Records of the Massachusetts General Hospital
Case 6-2012 — A 45-Year-Old Man with a History of Alcohol Abuse and Rapid Cognitive Decline
Presentation of Case. Dr. Clayton Knox (Medicine): A 45-year-old man with a history of alcoholism was admitted to this hospital because of rapid cognitive decline and worsening jaundice. During the previous 3 months, increasing fatigue and cough productive of yellow sputum and flecks of blood had…
- February 23, 2012
- Cho T.A., Larvie M., Tian D., Mino-Kenudson M.
- N Engl J Med 2012; 366:745-755
- CME
A 45-year-old man with a history of alcoholism was admitted to the hospital because of cognitive decline and jaundice. He had a 3-month history of cough, blood-tinged sputum, and vomiting. Imaging showed a peripherally enhancing brain lesion. A diagnostic procedure was performed.
- PDF
- Save
Editorial
Transplantation for Alcoholic Hepatitis — Time to Rethink the 6-Month “Rule”
Liver transplantation for alcoholic liver disease has been controversial since the advent of the procedure. The perception that alcohol-related liver disease is self-inflicted, combined with concerns about recidivism to alcohol use and poor adherence to post-transplantation care, has led the public…
- November 10, 2011
- Brown R.S.
- N Engl J Med 2011; 365:1836-1838
Liver transplantation for alcoholic liver disease has been controversial since the advent of the procedure. The perception that alcohol-related liver disease is self-inflicted, combined with concerns about recidivism to alcohol use and poor adherence to ...
- PDF
- Save
Clinical Practice
Treating Smokers in the Health Care Setting
Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations. Stage. A 45-year-old…
- September 29, 2011
- Fiore M.C. and Baker T.B.
- N Engl J Med 2011; 365:1222-1231
- CME
- Full Text Audio
Strategies to facilitate smoking cessation are reviewed, including documentation of smoking status for all patients, regular assessment of readiness to quit, counseling, and medications. Use of these strategies is guided by a patient's willingness and by coexisting conditions.
- PDF
- Save
Original Article
Placebo-Controlled Trial of Cytisine for Smoking Cessation
Tobacco smoking contributes to some 5 million premature deaths each year worldwide. It is highly addictive, with more than 95% of unaided attempts at cessation failing to last 6 months. Every year that a smoker delays quitting beyond the mid-30s, the person loses 3 months of life expectancy. The…
- September 29, 2011
- West R., Zatonski W., Cedzynska M., et al.
- N Engl J Med 2011; 365:1193-1200
- Free Full Text
Cytisine is a low-cost medication that is potentially beneficial in smoking cessation. In this placebo-controlled trial, 12-month abstinence rates were 8.4% among participants randomly assigned to 4 weeks of cytisine and 2.4% among participants assigned to placebo.
- PDF
- Save
Perspective
Moving beyond Parity — Mental Health and Addiction Care under the ACA
Enactment of the Mental Health Parity and Addiction Equity Act in 2008 was the culmination of a decades-long effort to improve insurance coverage for mental health and addiction treatment. The law's passage constituted a critical first step toward bringing care for people with mental health and…
- September 15, 2011
- Barry C.L. and Huskamp H.A.
- N Engl J Med 2011; 365:973-975
- Free Full Text
Enactment of the Mental Health Parity and Addiction Equity Act in 2008 improved insurance coverage for mental health and addiction treatment. Now, the Affordable Care Act could affect the financing and delivery of such care even more profoundly.
- PDF
- Save
Perspective
Drunk Driving, Distracted Driving, Moralism, and Public Health
In 1980, Candy Lightner gave a speech about a 13-year-old girl who was killed by a drunk driver with several previous arrests for driving while intoxicated (DWI). She ended by saying, "That little girl was my daughter." "The audience gasped," Lightner later reported. "The press jumped up and ran…
- September 8, 2011
- Lerner B.H.
- N Engl J Med 2011; 365:879-881
- Free Full Text
Can we blend the moral passion of anti–drunk-driving activism with epidemiologically based strategies for saving lives on the roads? The history of efforts to prevent automobile crashes offers lessons on various approaches and their possible synergy.
- PDF
- Save
Correspondence
“Bath Salts” Intoxication
To the Editor: The abuse of psychoactive "bath salts" (PABS) has become commonplace, and patients with PABS overdoses are presenting to emergency departments with increasing frequency. The primary ingredient of the synthetic designer drugs in these bath salts, which are not related to any hygiene…
- September 8, 2011
- N Engl J Med 2011; 365:967-968
- Free Full Text
This letter highlights recreational ingestion of bath salts containing methylenedioxypyrovalerone, a potent central nervous system stimulant. Intoxication that results in extreme sympathetic stimulation and profoundly alters mental status may be fatal.
- PDF
- Save
Images in Clinical Medicine
Toxic Effects of Levamisole in a Cocaine User
Figure 1.
- June 16, 2011
- Muirhead T.T. and Eide M.J.
- N Engl J Med 2011; 364:e52
- Free Full Text
A 54-year-old woman presented with a 2-day history of a painful, enlarging rash over her face (Panel A), ears (Panel B), breasts, and extremities. Laboratory studies revealed neutropenia (neutrophil count, 1070 per cubic millimeter) and lymphopenia (...
- PDF
- Save
Perspective
Our Bulging Medicine Cabinets — The Other Side of Medication Nonadherence
Last September, the Drug Enforcement Agency, in partnership with local police departments throughout the country, held a "National Prescription Drug Take-Back Day." More than 4000 police departments participated, and in Orange County, Florida, alone, more than 1.5 tons of prescription medications…
- April 28, 2011
- Shrank W.H.
- N Engl J Med 2011; 364:1591-1593
Millions of pounds of prescription medications go unused each year in the United States, where patients' leftover supplies may contribute to opiate abuse, increase the complexity of taking medications, promote antibiotic resistance, and lead to environmental pollution.
- PDF
- Save
Review Article
Current Concepts: The Gulf Oil Spill
One year after the Gulf oil spill (also known as the Deepwater Horizon oil spill, the BP oil spill, or the Gulf of Mexico oil spill), the full magnitude of the environmental, economic, and human health effects of this major disaster remain unknown. Despite a growing literature describing the impact…
- April 7, 2011
- Goldstein B.D., Osofsky H.J., Lichtveld M.Y.
- N Engl J Med 2011; 364:1334-1348
- Free Full Text
The 2010 Gulf Oil spill was an occupational, environmental, and community health disaster. This review summarizes the contaminants of concern, toxicologic consequences for humans and the ecosystem, lessons for worker safety, and mental health consequences in the community.
- PDF
- Save
Original Article
Whole-Genome Sequencing and Social-Network Analysis of a Tuberculosis Outbreak
Mycobacterium tuberculosis is an important infectious disease even in developed countries with extensive control programs. This is the case in British Columbia, Canada, where the 2007 incidence rate of 6.4 cases per 100,000 population exceeded the national average of 4.7 cases per 100,000…
- February 24, 2011
- Gardy J.L., Johnston J.C., Sui S.J.H., et al.
- N Engl J Med 2011; 364:730-739
- Free Full Text
- CME
An outbreak of tuberculosis occurred over a 3-year period in a medium-size community in British Columbia, Canada. The results of mycobacterial interspersed repetitive unitâ€“variable-number tandem-repeat (MIRU-VNTR) genotyping suggested the outbreak was clonal. Traditional contact tracing did not identify a source. We used whole-genome sequencing and social-network analysis in an effort to describe the outbreak dynamics at a higher resolution.
- PDF
- Save
Images in Clinical Medicine
Wound Botulism
Figure 1.
- December 16, 2010
- Sam A.H. and Beynon H.L.C.
- N Engl J Med 2010; 363:2444
- Free Full Text
A 42-year-old man with a history of subcutaneous heroin use presented to the hospital with slurred speech, diplopia, and dysphagia. The physical examination showed bilateral ptosis (Panel A), a sluggish pupillary response to light, bilateral sixth-cranial-...
- PDF
- Save
Original Article
Neonatal Abstinence Syndrome after Methadone or Buprenorphine Exposure
Opioid dependence during pregnancy is compounded by multiple risk factors contributing to adverse maternal, neonatal, and long-term developmental consequences.– Improved treatment options should reduce the public health and medical costs associated with the treatment of neonates exposed to…
- December 9, 2010
- Jones H.E., Kaltenbach K., Heil S.H., et al.
- N Engl J Med 2010; 363:2320-2331
- Free Full Text
In this trial comparing methadone with buprenorphine in opioid-dependent pregnant women, neonates exposed to buprenorphine required less morphine to treat neonatal abstinence syndrome (NAS) and had a significantly shorter duration of hospitalization and of treatment for NAS.
- PDF
- Save
Perspective
A Flood of Opioids, a Rising Tide of Deaths
Faced with an epidemic of drug abuse and overdose deaths involving prescription opioid pain relievers, the Food and Drug Administration (FDA) plans to require opioid makers to provide training for physicians and patient-education materials on the appropriate prescribing and use of extended-release…
- November 18, 2010
- Okie S.
- N Engl J Med 2010; 363:1981-1985
- Free Full Text
Faced with an epidemic of drug abuse and overdose deaths, the FDA has proposed a Risk Evaluation and Mitigation Strategy for prescription opioid pain relievers, involving improved education for physicians and patients about risks associated with long-acting opioids.
- PDF
- Save
Review Article
Mechanisms of Disease: Nicotine Addiction
Cigarette smoking remains a leading cause of preventable disease and premature death in the United States and other countries. On average, 435,000 people in the United States die prematurely from smoking-related diseases each year; overall, smoking causes 1 in 5 deaths. The chance that a lifelong…
- June 17, 2010
- Benowitz N.L.
- N Engl J Med 2010; 362:2295-2303
This review gives an account of the cigarette as a highly efficient nicotine delivery system. It explains how nicotine induces pleasure, reduces stress and anxiety, and causes addiction to tobacco smoking. The basis of nicotine addiction rests on its effects on the brain, but addiction is also influenced by learned or conditioned factors, genetics, and social and environmental conditions.
- PDF
- Save
Perspective
Medical Marijuana and the Law
The U.S. legal landscape surrounding "medical marijuana" is complex and rapidly changing. Fourteen states — California, Alaska, Oregon, Washington, Maine, Hawaii, Colorado, Nevada, Vermont, Montana, Rhode Island, New Mexico, Michigan, and most recently, New Jersey — have passed laws eliminating…
- April 22, 2010
- Hoffmann D.E. and Weber E.
- N Engl J Med 2010; 362:1453-1457
- Free Full Text
The U.S. legal landscape surrounding “medical marijuana” is complex and rapidly changing. Diane Hoffmann and Ellen Weber describe evolving legislation.
- PDF
- Save
Images in Clinical Medicine
Extensive Bowel Infarction
Figure 1.
- November 12, 2009
- Cheng J. and Pande G.
- N Engl J Med 2009; 361:1979
- Free Full Text
A 45-year-old man presented to the emergency room with abdominal pain that had been increasing over the previous week and hematemesis and melena that had begun in the preceding 12 hours. He had drunk 36 alcoholic drinks per day for 20 years and had been ...
- PDF
- Save
Original Article
Diacetylmorphine versus Methadone for the Treatment of Opioid Addiction
Opioid dependence, most commonly manifested as heroin dependence, is a chronic relapsing condition that is estimated to affect more than 1 million persons in North America. The risks of opioid dependence include fatal overdoses, infections (including endocarditis, human immunodeficiency virus…
- August 20, 2009
- Oviedo-Joekes E., Brissette S., Marsh D.C., et al.
- N Engl J Med 2009; 361:777-786
- Free Full Text
In this 12-month randomized trial involving 251 long-term heroin users, injectable diacetylmorphine (the active ingredient in heroin) was more effective than oral methadone in achieving retention in treatment for addiction and in reducing illicit-drug use and other illegal activity. As compared with methadone, injectable diacetylmorphine was associated with more serious adverse events, including seizures and drug overdoses.
- PDF
- Save

Page

Medical Meetings Pediatrics Conferences and Meetings

2012 Certifying Examinations of the American Board of Pediatrics

The general pediatrics examination will be held in various cities, Oct. 16-18. Registration for first-time applicants is ongoing through May 3. Registration for re-registrants is ongoing through May 24. The following subspecialty examinations will be held in various cities: "Hospice and Palliative Medicine" (Oct. 4); "Pediatric Transplant Hepatology" (Oct. 11); "Pediatric Cardiology" (Nov. 7); "Pediatric Pulmonology" (Nov. 8); "Medical Toxicology" (Nov. 12); and "Pediatric Critical Care Medicine" (Nov. 14). Registration for first-time applicants is ongoing through April 30. Registration for re-registrants is ongoing through June 15.

Contact the American Board of Pediatrics, 111 Silver Cedar Court, Chapel Hill, NC 27514-1513; or call (919) 929-0461; or fax (919) 918-7114 or (919) 929-9255; or see http://www.abp.org .

More Medical Meetings

Trends: Most Viewed (Last Week)

More Trends