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  • Perspective

    We have an unprecedented opportunity to create a high-performance health system in the United States. Recent statutes, including the Affordable Care Act, the American Recovery and Reinvestment Act, and the Health Information Technology for Economic and Clinical Health Act, provide the federal…

    • May 24, 2012
    • Blumenthal D.
    • N Engl J Med 2012; 366:1953-1955
    • Free Full Text

    The Commonwealth Fund Commission on a High Performance Health System believes the government should facilitate communities' efforts to improve care for patients with multiple chronic conditions, through improved primary care, payment reform, and better information.

  • Perspective

    Gaining prompt access to primary care is a growing concern for all American adults. In Massachusetts, average wait times for new patients to obtain an internal-medicine appointment rose by 82% in the 2 years after health insurance coverage was expanded; current wait times average 36 days for family…

    • May 24, 2012
    • Ghorob A. and Bodenheimer T.
    • N Engl J Med 2012; 366:1955-1957
    • Free Full Text

    Gaining prompt access to primary care is a growing concern for all American adults. In Massachusetts, average wait times for new patients to obtain an internal-medicine appointment rose by 82% in the 2 years after health insurance coverage was expanded; ...

  • Perspective

    Quietly, Washington policymakers have begun to concede the need to weigh health care's benefits against its costs if our country is to avert fiscal ruin. That costs must be counted against benefits is common sense in other domains — and among health policy professionals. But it's anathema in…

    • May 24, 2012
    • Bloche M.G.
    • N Engl J Med 2012; 366:1951-1953
    • Free Full Text

    The belief that cost should be no object in health care has limited efforts to control medical spending; elected officials generally insist that cutting services that yield no value will be sufficient. But eliminating such waste would merely postpone the reckoning.

  • Perspective

    Bioethics has long approached cost containment under the heading of "allocation of scarce resources." Having thus named the nail, bioethics has whacked away at it with the theoretical hammer of distributive justice. But in the United States, ethical debate is now shifting from rationing to the…

    • May 24, 2012
    • Brody H.
    • N Engl J Med 2012; 366:1949-1951
    • Free Full Text
    • Audio

    Waste in U.S. health care — spending on interventions that don't benefit patients — amounts to at least 30% of health care spending and is a major driver of cost increases. So the ethical debate about cost containment is shifting focus from rationing to waste avoidance.

  • PerspectiveOnline First

    Primary care physicians, long in the doldrums over their incomes and challenging work–life balance, may be heartened by recent steps taken by policymakers and payers signaling the increased recognition of the foundational role they could play in a restructured health care delivery system. Hopeful…

    • May 23, 2012
    • Iglehart J.K.
    • 10.1056/NEJMp1205537
    • Free Full Text

    Primary care physicians, long in the doldrums over their incomes and challenging work–life balance, may be heartened by recent steps taken by policymakers and payers signaling the increased recognition of the foundational role they could play in a ...

  • PerspectiveOnline First

    In recent decades, biomarkers have become essential in diagnosing disease and assessing patients' responses to therapy. The increasing quantitative rigor and efficiency of these tests have led to the possibility of "personalized medicine." Despite such progress, the way in which a physician uses…

    • May 23, 2012
    • Kesselheim A.S. and Karlawish J.
    • 10.1056/NEJMp1204164
    • Free Full Text

    In recent decades, biomarkers have become essential in diagnosing disease and assessing patients' responses to therapy. The increasing quantitative rigor and efficiency of these tests have led to the possibility of “personalized medicine.” Despite such ...

  • Perspective

    Nearly 2.5 million Americans die each year, leaving behind an even larger group of grief-stricken people. Such a universal human experience as grief is recognized by the lay public and medical professionals alike as an entirely normal and expected emotional response to loss. Clinicians and…

    • May 17, 2012
    • Friedman R.A.
    • N Engl J Med 2012; 366:1855-1857
    • Free Full Text

    Though bereaved persons often have depressive symptoms, grief typically runs its course within 2 to 6 months and requires no treatment. But the new edition of the Diagnostic and Statistical Manual of Mental Disorders may define bereavement as a depressive disorder.

  • Perspective

    The primary care doctor is a rapidly evolving species — and in the future could become an endangered one. As the United States grapples with the dual challenges of making health care more widely available and reducing the national price tag, it's hard to say how primary care physicians will fit…

    • May 17, 2012
    • Okie S.
    • N Engl J Med 2012; 366:1849-1853
    • Free Full Text
    • Audio

    The primary care doctor is a rapidly evolving species — and could become an endangered one. As we grapple with making health care more widely available and reducing its cost, it's hard to say how primary care physicians will fit into emerging delivery models.

  • Perspective

    The debate over revising the Diagnostic and Statistical Manual of Mental Disorders (DSM) is of more than intramural interest, for the way in which the promised fifth edition (DSM-5) resolves the debate will shape the nature and scope of psychiatric services for years to come. Now established as the…

    • May 17, 2012
    • McHugh P.R. and Slavney P.R.
    • N Engl J Med 2012; 366:1853-1855
    • Free Full Text

    In its fifth edition, the Diagnostic and Statistical Manual of Mental Disorders should correct a categorization scheme based on clinical appearance, which offers no way of making sense of mental disorders and fosters a diagnostic method reliant on symptom checklists.

  • PerspectiveOnline First

    The political seas roiled by the Affordable Care Act (ACA) have grown more volatile in the 2 years since its passage. Whether it is the constitutionality of the insurance mandate, the economic feasibility of the Medicaid expansion, or controversy over the conscience clauses, much has been said and…

    • May 16, 2012
    • Breen J.O.
    • 10.1056/NEJMp1202039
    • Free Full Text

    The political seas roiled by the Affordable Care Act (ACA) have grown more volatile in the 2 years since its passage. Whether it is the constitutionality of the insurance mandate, the economic feasibility of the Medicaid expansion, or controversy over the ...

  • PerspectiveOnline First

    In December, 2011, Washington State's Health Care Authority announced its intention to stop paying for emergency department (ED) visits by Medicaid beneficiaries "when those visits are not necessary for that place of service." To identify unnecessary visits, the state proposed a list of…

    • May 16, 2012
    • Kellermann A.L. and Weinick R.M.
    • 10.1056/NEJMp1203247
    • Free Full Text

    In December, 2011, Washington State's Health Care Authority announced its intention to stop paying for emergency department (ED) visits by Medicaid beneficiaries “when those visits are not necessary for that place of service.”1 To identify unnecessary ...

  • Perspective

    Human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV) exact a high toll worldwide. Both can lead to chronic disease, cancer, and death, and neither can be eradicated with the use of current therapies. Antiviral drug resistance often develops after patients have received treatment…

    • May 10, 2012
    • Kourtis A.P., Bulterys M., Hu D.J., Jamieson D.J.
    • N Engl J Med 2012; 366:1749-1752
    • Free Full Text

    Human immunodeficiency virus and hepatitis B virus exact a high toll worldwide. Both can lead to chronic disease, cancer, and death, and neither can be eradicated with the use of current therapies. Coinfection with the two viruses represents a major global health problem.

  • Perspective

    Barely 20 years ago, such a high proportion of childhood deaths globally was attributable to measles that the going estimate of more than 1 million measles-related deaths per year was almost certainly an underestimate. Pediatric wards in the developing world were filled with patients with measles…

    • May 10, 2012
    • Mulholland E.K., Griffiths U.K., Biellik R.
    • N Engl J Med 2012; 366:1755-1757
    • Interactive/Multimedia

    Between 2000 and 2008, measles control improved markedly worldwide, but with poorer countries focused on polio eradication and some richer countries falling prey to opposition to vaccination, the measles genie seems to have slipped out of the bottle in recent years.

  • Perspective

    The Medicare Pioneer and Shared Savings Accountable Care Organization (ACO) programs offer health care provider organizations contracts with Medicare whereby the organizations assume financial risk and are rewarded for providing high-quality care at lower cost. ACO spending targets will be…

    • May 10, 2012
    • McWilliams J.M. and Song Z.
    • N Engl J Med 2012; 366:e29
    • Free Full Text

    Since the spending targets in Medicare's new accountable care organization (ACO) programs are being set on the basis of national, rather than local, rates of spending growth, ACOs could gain or lose financially without altering their delivery of care.

  • Perspective

    No drug provides health benefits without some degree of risk, and risk–benefit assessments require ongoing review as new data become available. This is certainly the case for the use of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors — statins — and the risk of new-onset…

    • May 10, 2012
    • Goldfine A.B.
    • N Engl J Med 2012; 366:1752-1755
    • Free Full Text
    • Audio

    The Food and Drug Administration has added information to statin labels regarding an effect on diabetes, noting reported increases in glycated hemoglobin and fasting serum glucose levels but adding that it believes that the cardiovascular benefits outweigh the risks.

  • PerspectiveOnline First

    Osteoporosis, a disease characterized by reduced bone mass and increased skeletal fragility, affects 10 million Americans; another 34 million are at risk for it. Bisphosphonates are widely prescribed for osteoporosis; more than 150 million prescriptions were dispensed to outpatients between 2005…

    • May 9, 2012
    • Whitaker M., Guo J., Kehoe T., Benson G.
    • 10.1056/NEJMp1202619
    • Free Full Text

    Osteoporosis, a disease characterized by reduced bone mass and increased skeletal fragility, affects 10 million Americans; another 34 million are at risk for it. Bisphosphonates are widely prescribed for osteoporosis; more than 150 million prescriptions ...

  • PerspectiveOnline First

    In the 21st century, osteoporosis, a disease once considered an inevitable consequence of aging, is both diagnosable and treatable. Large, randomized, controlled trials have shown that bisphosphonate therapy for 3 to 4 years is effective in reducing the risk of both nonvertebral and vertebral…

    • May 9, 2012
    • Black D.M., Bauer D.C., Schwartz A.V., Cummings S.R., Rosen C.J.
    • 10.1056/NEJMp1202623
    • Free Full Text

    In the 21st century, osteoporosis, a disease once considered an inevitable consequence of aging, is both diagnosable and treatable. Large, randomized, controlled trials have shown that bisphosphonate therapy for 3 to 4 years is effective in reducing the ...

  • Perspective

    Although the media and the U.S. public focused primarily on the minimum-coverage requirement, or individual mandate, during the recent oral arguments in the challenges to the Affordable Care Act (ACA) before the Supreme Court, the most important issue before the Court may well be the…

    • May 3, 2012
    • Jost T.S.
    • N Engl J Med 2012; 366:e27
    • Free Full Text

    Although the media and the U.S. public focused primarily on the minimum-coverage requirement, or individual mandate, during the recent oral arguments in the challenges to the Affordable Care Act (ACA) before the Supreme Court, the most important issue ...

  • Perspective

    One area of amazing recent medical advances has been childhood cancers, for which survival rates have quadrupled over the past four decades and now exceed 80%. This progress has been driven not only by the introduction of novel therapies but also by the remarkable level of patient and physician…

    • May 3, 2012
    • Gelijns A.C. and Gabriel S.E.
    • N Engl J Med 2012; 366:1659-1661

      To accelerate the pace and spread of scientific discovery, we must look beyond translation and integrate clinical research with medical practice, creating a patient-centered, science-driven health care enterprise. But there are barriers to doing so.

    • Perspective

      Thirty years ago, an intern had a conversation with a patient that he regrets to this day. The patient, a young man with widely metastatic lymphoma, unresponsive to chemotherapy, now had progressive dyspnea. The intern knew that even with intubation, his patient would soon die. Although the norm at…

      • May 3, 2012
      • Lamas D. and Rosenbaum L.
      • N Engl J Med 2012; 366:1655-1657

        Paternalism in discussing resuscitation status has given way to an approach in which patients may be asked to choose from a bewildering array of medical options, but physicians-in-training are rarely taught how to lead such conversations confidently and effectively.

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      Medical Meetings Pediatrics Conferences and Meetings

      2012 Certifying Examinations of the American Board of Pediatrics

      The general pediatrics examination will be held in various cities, Oct. 16-18. Registration for first-time applicants is ongoing through May 3. Registration for re-registrants is ongoing through May 24. The following subspecialty examinations will be held in various cities: "Hospice and Palliative Medicine" (Oct. 4); "Pediatric Transplant Hepatology" (Oct. 11); "Pediatric Cardiology" (Nov. 7); "Pediatric Pulmonology" (Nov. 8); "Medical Toxicology" (Nov. 12); and "Pediatric Critical Care Medicine" (Nov. 14). Registration for first-time applicants is ongoing through April 30. Registration for re-registrants is ongoing through June 15.

      Contact the American Board of Pediatrics, 111 Silver Cedar Court, Chapel Hill, NC 27514-1513; or call (919) 929-0461; or fax (919) 918-7114 or (919) 929-9255; or see http://www.abp.org .

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