Original Article

Mutation of FOXL2 in Granulosa-Cell Tumors of the Ovary

Sohrab P. Shah, Ph.D., Martin Köbel, M.D., Janine Senz, B.Sc., Ryan D. Morin, M.Sc., Blaise A. Clarke, M.B., B.Ch., Kimberly C. Wiegand, B.Sc., Gillian Leung, B.Sc., Abdalnasser Zayed, B.Sc., Erika Mehl, B.M.L.Sc., Steve E. Kalloger, B.Sc., Mark Sun, B.Sc., Ryan Giuliany, Erika Yorida, B.M.L.Sc., Steven Jones, Ph.D., Richard Varhol, M.Sc., Kenneth D. Swenerton, M.D., Dianne Miller, M.D., Philip B. Clement, M.D., Colleen Crane, B.Tech., Jason Madore, M.Sc., Diane Provencher, M.D., Peter Leung, Ph.D., Anna DeFazio, Ph.D., Jaswinder Khattra, M.Sc., Gulisa Turashvili, M.D., Ph.D., Yongjun Zhao, M.Sc., D.V.M., Thomas Zeng, M.Sc., J.N. Mark Glover, Ph.D., Barbara Vanderhyden, Ph.D., Chengquan Zhao, M.D., Christine A. Parkinson, Ph.D., M.R.C.P., Mercedes Jimenez-Linan, Ph.D., David D.L. Bowtell, Ph.D., Anne-Marie Mes-Masson, Ph.D., James D. Brenton, M.D., F.R.C.P., Samuel A. Aparicio, B.M., B.Ch., Niki Boyd, Ph.D., Martin Hirst, Ph.D., C. Blake Gilks, M.D., Marco Marra, Ph.D., and David G. Huntsman, M.D.

N Engl J Med 2009; 360:2719-2729June 25, 2009