Original Article

Detection of Mutations in EGFR in Circulating Lung-Cancer Cells

Shyamala Maheswaran, Ph.D., Lecia V. Sequist, M.D., M.P.H., Sunitha Nagrath, Ph.D., Lindsey Ulkus, B.S., Brian Brannigan, B.A., Chey V. Collura, M.S., Elizabeth Inserra, B.S., Sven Diederichs, Ph.D., A. John Iafrate, M.D., Ph.D., Daphne W. Bell, Ph.D., Subba Digumarthy, M.D., Alona Muzikansky, M.S., Daniel Irimia, Ph.D., Jeffrey Settleman, Ph.D., Ronald G. Tompkins, M.D., Thomas J. Lynch, M.D., Mehmet Toner, Ph.D., and Daniel A. Haber, M.D., Ph.D.

N Engl J Med 2008; 359:366-377July 24, 2008