Videos in Clinical Medicine

Bone Marrow Aspiration and Biopsy

Suman Malempati, M.D., Sarita Joshi, M.D., Susanna Lai, M.P.H., Dana A.V. Braner, M.D., and Ken Tegtmeyer, M.D.

N Engl J Med 2009; 361:e28October 8, 2009DOI: 10.1056/NEJMvcm0804634

Article

• Download Video
• Windows Media version
• Kinoma Player version
• M4V version

About the Procedure

This video will demonstrate the procedure for bone marrow aspiration and bone marrow biopsy from the posterior iliac crest. Obtaining a bone marrow aspirate and core biopsy is often necessary when evaluating a patient who has a hematologic abnormality. Examining bone marrow is also useful in the diagnosis of metastatic spread of nonhematologic malignancies and to diagnose metabolic disorders. Gather the necessary equipment prior to performing the procedure. You will require equipment for sterile skin preparation and a sterile field, 1 percent lidocaine buffered with sterile sodium bicarbonate, a 25-gauge needle and 5-ml syringe, a bone marrow aspiration needle, . . .

No potential conflict of interest relevant to this article was reported.

References

References

1. 1

   Bain BJ. Bone marrow trephine biopsy. J Clin Pathol 2001;54:737-742
   CrossRef | Web of Science | Medline

2. 2

   Bain BJ. Bone marrow biopsy morbidity and mortality. Br J Haematol 2003;121:949-951
   CrossRef | Web of Science | Medline

3. 3

   Bain BJ. Morbidity associated with bone marrow aspiration and trephine biopsy -- a review of UK data for 2004. Haematologica 2006;91:1293-1294
   Web of Science | Medline

4. 4

   Arellano-Rodrigo E, Real MI, Muntanola A, et al. Successful treatment by selective arterial embolization of severe retroperitoneal hemorrhage secondary to bone marrow biopsy in post-polycythemic myelofibrosis. Ann Hematol 2004;83:67-70
   CrossRef | Web of Science | Medline

5. 5

   Wahid SF, Md-Anshar F, Mukari SA, Rahmat R. Massive retroperitoneal hematoma with secondary hemothorax complicating bone marrow trephine biopsy in polycythemia vera. Am J Hematol 2007;82:943-944
   CrossRef | Web of Science | Medline

Citing Articles (5)

Citing Articles

1. 1

   Axel Matzdorff. Treatment guidelines & algorithm. In: Current & Emerging Treatments for Immune Thrombocytopenia. Future Medicine Ltd, 2013:30-45.
   

2. 2

   H. Boukhari. (2012) Hémopéricarde compliquant une ponction sternale. Annales françaises de médecine d'urgence 2:3, 193-195
   

3. 3

   Karl S. Theil. Bone Marrow Processing and Normal Morphology. In: Laboratory Hematology Practice. Wiley-Blackwell, 2012:279-299.
   

4. 4

   Mary Kelly, Gerard Crotty, Kanthi Perera, Maura Dowling. (2011) Evaluation of bone marrow examinations performed by an advanced nurse practitioner: An extended role within a haematology service. European Journal of Oncology Nursing 15:4, 335-338
   

5. 5

   (2010) Bone Marrow Aspiration and Biopsy. New England Journal of Medicine 362:2, 182-183
   Free Full Text

Letters