Perspective

Perspective Roundtable

CABG vs. Stenting — Clinical Implications of the SYNTAX Trial

Thomas H. Lee, M.D., L. David Hillis, M.D., and Elizabeth G. Nabel, M.D.

N Engl J Med 2009; 360:e10February 19, 2009

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Poll Results

Contributors

In the international SYNTAX trial, 1800 patients with three-vessel or left main coronary artery disease were randomly assigned to either revascularization with coronary-artery bypass grafting (CABG) or percutaneous coronary intervention involving drug-eluting stents. The need for repeat revascularization was significantly lower with CABG, but the risk of stroke was significantly higher — a tradeoff that must be considered in making clinical decisions regarding patients with advanced coronary disease. In a roundtable discussion moderated by Dr. Thomas Lee, cardiologists David Hillis and Elizabeth Nabel debate the implications of these findings for clinical practice.

View video of this roundtable discussion, participate in the poll, and contribute your comments. Polling and commenting close March 4, 2009.

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Citing Articles (4)

Citing Articles

1. 1

   Hui-Chun Huang, Hsien-Li Kao, Xue-Ming Wu, Sheoi-Shen Wang, Ron-Bin Hsu, Yi-Lwun Ho, Ming-Fong Chen. (2010) Long-term prognosis in ethnic Chinese patients with unprotected left main coronary artery disease. Clinical Research in Cardiology 99:7, 437-443
   CrossRef

2. 2

   Christoph H. R. Wiese, Utz E. Bartels, York A. Zausig, Jochen Pfirstinger, Bernhard M. Graf, Gerd G. Hanekop. (2009) Prehospital emergency treatment of palliative care patients with cardiac arrest: a retrolective investigation. Supportive Care in Cancer
   CrossRef

3. 3

   (2009) Percutaneous Coronary Intervention versus Coronary-Artery Bypass Grafting. New England Journal of Medicine 360:25, 2672-2675
   Full Text

4. 4

   Peter K. Smith. (2009) Treatment selection for coronary artery disease: The collision of a belief system with evidence. The Journal of Thoracic and Cardiovascular Surgery 137:5, 1050-1053
   CrossRef

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