Original Article
Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico
N Engl J Med 2009; 361:680-689August 13, 2009
- Abstract
Background
In late March 2009, an outbreak of a respiratory illness later proved to be caused by novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in Mexico. We describe the clinical and epidemiologic characteristics of persons hospitalized for pneumonia at the national tertiary hospital for respiratory illnesses in Mexico City who had laboratory-confirmed S-OIV infection, also known as swine flu.
Methods
We used retrospective medical chart reviews to collect data on the hospitalized patients. S-OIV infection was confirmed in specimens with the use of a real-time reverse-transcriptase–polymerase-chain-reaction assay.
Results
From March 24 through April 24, 2009, a total of 18 cases of pneumonia and confirmed S-OIV infection were identified among 98 patients hospitalized for acute respiratory illness at the National Institute of Respiratory Diseases in Mexico City. More than half of the 18 case patients were between 13 and 47 years of age, and only 8 had preexisting medical conditions. For 16 of the 18 patients, this was the first hospitalization for their illness; the other 2 patients were referred from other hospitals. All patients had fever, cough, dyspnea or respiratory distress, increased serum lactate dehydrogenase levels, and bilateral patchy pneumonia. Other common findings were an increased creatine kinase level (in 62% of patients) and lymphopenia (in 61%). Twelve patients required mechanical ventilation, and seven died. Within 7 days after contact with the initial case patients, a mild or moderate influenza-like illness developed in 22 health care workers; they were treated with oseltamivir, and none were hospitalized.
Conclusions
S-OIV infection can cause severe illness, the acute respiratory distress syndrome, and death in previously healthy persons who are young to middle-aged. None of the secondary infections among health care workers were severe.
Media in This Article
Figure 1
Emergency Room Consultations for Pneumonia or Respiratory Infection, Including Influenza-like Illness, at the National Institute of Respiratory Diseases of Mexico.Figure 2
Clinical Courses of the Study Patients.Article Activity
- Article
In April 2009, the Mexican Secretariat of Health reported an outbreak of respiratory disease. In the affected patients, a novel swine-origin influenza A (H1N1) virus (S-OIV) with molecular features of North American and Eurasian swine, avian, and human influenza viruses1-4 was found. In the same month, the World Health Organization (WHO) classified the global spread of this virus as a public health event of international concern. After documentation of human-to-human transmission of the virus in at least three countries of two WHO regions, the WHO raised the pandemic level to 6.5
As of May 29, 2009, Mexico had reported 4910 confirmed cases and 85 deaths caused by S-OIV.6 Mexico has reported the greatest number of cases of severe clinical presentations and death,1 whereas other countries have reported predominantly mild cases of influenza-like illness.
This case series describes the clinical and epidemiologic characteristics of the first 18 persons with pneumonia and laboratory-confirmed S-OIV infection (also known as swine flu) hospitalized at the National Institute of Respiratory Diseases (INER) in Mexico. We also describe apparent transmission of this infection to health care workers during the initial days of the outbreak.
Methods
INER is the Mexican national tertiary care and research center devoted to respiratory diseases. The 178-bed facility provides clinical services primarily for the uninsured population of Mexico City and neighboring states. We retrospectively reviewed medical charts and radiologic and laboratory findings. This study was determined to be exempt from the requirement of institutional review, because it was conducted as part of a public health investigation into retrospective data. All tests and procedures were performed at the request of the physicians in charge of the patients. All study patients had influenza-like illness with opacities found on the chest radiograph (revealing pneumonia) and had laboratory-confirmed S-OIV infection. We also reviewed clinical data from a group of 21 hospitalized patients with influenza-like illness and pneumonia but with a negative result on reverse-transcriptase–polymerase-chain-reaction (RT-PCR) testing for influenza A (H1N1).
Microbiologic Studies
Nasopharyngeal-swab specimens were collected at admission, and bronchial-aspirate samples were obtained after tracheal intubation. Specimens were placed in transport medium and kept at a temperature from 2 to 4°C. RT-PCR testing was done in accordance with published guidelines from the U.S. Centers for Disease Control and Prevention (CDC).7 Primers and probes for S-OIV were recently developed and distributed to the Mexican Secretariat of Health and its affiliated national institutions by the CDC. In addition, respiratory specimens from all patients were tested with the use of a multiplex PCR assay for respiratory viral and atypical bacterial panels (Seagene) for the detection of influenza A, influenza B, adenovirus, respiratory syncytial virus, parainfluenza (types 1, 2, and 3), human metapneumovirus, rhinovirus, Legionella pneumophila, Chlamydophila pneumoniae, and Mycoplasma pneumoniae.
Statistical Analysis
Data analysis was conducted using STATA statistical software.8 We compared clinical characteristics on admission between patients positive for S-OIV who died and those who survived and between patients who were positive for S-OIV and those who were negative for S-OIV. The risk of death was analyzed by means of a univariate Cox proportional-hazards model; odds ratios were calculated and Fisher's exact test was performed for dichotomous categorical variables. Continuous data were tested by means of the Wilcoxon rank-sum test. All reported P values are two-sided and were not adjusted for multiple testing.
Results
Study Patients
The number of emergency room visits for pneumonia or influenza-like illness increased considerably at the INER in Mexico City during the last week of March 2009, peaking in late April and decreasing during the first week of May (Figure 1Figure 1
Emergency Room Consultations for Pneumonia or Respiratory Infection, Including Influenza-like Illness, at the National Institute of Respiratory Diseases of Mexico.). From March 24 through April 24, 2009, a total of 214 emergency room consultations for cases of pneumonia or influenza-like illness were registered, 98 of which required hospitalization. Of these cases, 18 confirmed cases of S-OIV infection, with pneumonia and influenza-like illness, are the focus of this report.Characteristics of the 18 study patients with confirmed S-OIV infection are listed in Table 1Table 1
Characteristics of the 18 Study Patients Who Had Confirmed Infection with Novel Swine-Origin Influenza A (H1N1) Virus., and Table S1 in the Supplementary Appendix (available with the full text of this article at NEJM.org). The ages of the patients ranged from 9 months to 61 years (median, 38 years). More than half the patients were between 13 and 47 years of age, and 90% were less than 52 years of age. Nine patients (50%) were male.All patients resided in the Mexico City greater metropolitan area. Eight patients had preexisting medical conditions: arterial hypertension (in three patients), non–type 1 diabetes mellitus (in three, one of whom also had hypertension), asthma (in two), and obstructive sleep apnea (in one). Only three of the patients had undergone seasonal influenza vaccination in 2008–2009; all three survived without requiring mechanical ventilation. None of the patients had a history of pneumococcal vaccination. Among the 14 patients whose occupation was recorded, 6 were students, 2 were taxi drivers, 3 were housekeepers, 1 was a locksmith, 1 was an employee of a billiards parlor, and 1 was a physician who did not have clinical duties and was not an INER employee.
The time between onset of symptoms and admission to the hospital ranged from 4 to 25 days (median, 6) (Figure 2Figure 2
Clinical Courses of the Study Patients.). All patients had fever, with temperatures higher than 38°C, cough, and dyspnea or respiratory distress. Four of the five children (all under 14 years of age) had diarrhea, and only two patients (11%) reported wheezing. The median Acute Physiology and Chronic Health Evaluation II score9 was 14 (range, 4 to 32), and the median Sequential Organ Failure Assessment score10 was 6 (range, 1 to 13); both were higher, indicating more severe abnormalities among the patients who died than among those who lived (Table 2Table 2
Survival and Death among the 18 Study Patients Who Had Confirmed Infection with Novel Swine-Origin Influenza A (H1N1) Virus.).Twelve patients sought medical care at other institutions as outpatients before hospitalization at INER and were treated with one or more antibiotics: ceftriaxone (five patients), amikacin (three), azithromycin (one), amoxicillin–clavulanate (two) or other macrolides (three), or another agent (two). Except for two patients transferred from other health centers, the reported hospitalization was the first hospitalization related to the disease.
Laboratory Results
At the time of admission, all 16 tested patients had elevated lactate dehydrogenase levels; levels in 10 patients exceeded 1000 IU per liter (range, 1086 to 6309). Ten of the 16 patients had increased creatine kinase levels, which were above 1000 IU per liter (range, 1099 to 5122) in 5 patients. Eleven of all 18 patients (61%) had lymphopenia (<1000 lymphocytes per cubic millimeter), 2 patients had more than 10,000 leukocytes per cubic millimeter, and 2 patients had mild thrombocytopenia at admission. Patient 3 had myocardial ischemia, as revealed on electrocardiography, with myocardial infarction documented on autopsy. Three patients had elevated creatinine levels (1.8 to 4.6 mg per deciliter [159 to 407 μmol per liter]) at admission. Four patients had d-dimer levels greater than 1000 IU per liter, and 11 patients had elevated aminotransferase levels (aspartate aminotransferase, 50 to 65 U per liter; alanine aminotransferase, 43 to 147 U per liter). Results of other routine tests were within normal limits.
The following bacterial cultures obtained within 24 hours after admission were negative: cultures of blood specimens from six patients, of bronchial aspirate samples from two patients, and of pleural-fluid specimens from one patient. Three of these patients had received antibiotics within 24 to 48 hours before admission. No other respiratory viruses or atypical bacteria were identified by means of PCR assay in any patient tested.
All 18 patients had radiologically confirmed pneumonia (Figure 3AFigure 3
Initial Radiograph of the Lung and Lung-Tissue Sample from Patient 3., and Figure S2 and S3 in the Supplementary Appendix) with bilateral patchy alveolar opacities (predominantly basal), affecting three or four lung quadrants in 11 patients. Also common were linear, reticular, or nodular shadows (interstitial opacities). Findings on chest radiographs were consistent with the acute respiratory distress syndrome in all patients requiring mechanical ventilation.11 Treatment
None of the patients had received oseltamivir before admission; 14 received it in the hospital, at a dose of 75 mg twice a day for a minimum of 5 days; 11 began receiving it at admission (a mean of 8 days after the onset of symptoms) and 3 between 2 and 10 days after admission. Four patients who survived did not receive oseltamivir. After admission, 17 patients received ceftriaxone and 10 received clarithromycin. Additional antibiotics were prescribed in several patients, on the basis of their clinical course: three were given levofloxacin; seven, vancomycin; five, cefepime; five, imipenem; and two, dicloxacillin.
Clinical Course during Hospital Stay
Respiratory distress requiring intubation and mechanical ventilation developed in 10 patients within the first 24 hours after admission. These patients had a median oxygen saturation of 71% (interquartile range, 64 to 77) in the absence of supplementary oxygen (2240 m above sea level), and treatment of eight patients involved positive end-expiratory pressure at or above 16 cm of water. Two additional patients required mechanical ventilation during their stay in the hospital (Table S2 in the Supplementary Appendix). Duration of mechanical ventilation ranged from 7 to 30 days in patients who survived and from 4 to 17 days in patients who died. Norepinephrine infusion was begun in 9 of 18 patients (50%) during the period of hospitalization, and 5 patients received corticosteroids (hydrocortisone at a dose of 300 mg per day or methylprednisolone at a dose of 60 mg per day). Of the six patients in whom renal failure developed, five died. Seven patients had multiorgan system failure. None of the patients had disseminated intravascular coagulation or neurologic complications. Four patients had ventilator-associated pneumonia, each case with a different cause: Acinetobacter baumannii, Achromobacter xylosoxidans, methicillin-resistant Staphylococcus aureus, or Escherichia coli.
Of the 18 patients, 7 died, and 11 recovered and were discharged from the hospital. Patients died within 10 to 23 days (mean, 14) after the onset of illness and between 4 and 18 days (mean, 9 days) after admission. Figure 3B shows a lung-tissue specimen from the autopsy of Patient 3, a 43-year-old patient who died after a 14-day illness complicated by acute renal failure and myocardial infarction. Pathological evaluation of the lung showed diffuse alveolar damage, thick hyaline membranes, and prominent fibroblast proliferation.
Patients with confirmed S-OIV infection had more severe disease, including a higher death rate (Table S2 in the Supplementary Appendix), than did hospitalized patients with negative test results. The median time from illness onset to collection of samples for viral testing was 9 days (range, 3 to 46) among the 18 patients who were positive for S-OIV infection and 10 days (range, 3 to 27) among those with negative test results (P=0.50).
Clinical Infection in Contacts and Health Care Workers
Patients identified a total of 82 family contacts, 20 of whom had respiratory symptoms within a week after the patient was hospitalized. Of the 20, 4 required hospitalization, including 3 contacts of Patient 6; 1 contact who had Down's syndrome died in another hospital from respiratory failure. Patient 2, in whom severe respiratory failure developed, is the mother of Patient 9, who had milder disease and received early treatment with oseltamivir.
Influenza-like illness or respiratory symptoms developed in 22 of 190 health care workers caring for the first three patients with confirmed S-OIV infection in the emergency room and the intensive care unit, including 19 of 104 workers who were within 2 m of a patient or had direct contact. These 22 workers received oseltamivir for 5 days and were sent home for 3 to 7 days. They had mild-to-moderate disease, and none required hospitalization. Three of the 22 workers, who were nurses in the emergency room, had nasopharyngeal-aspirate samples that were positive for S-OIV. After infection-control measures were strictly enforced — with patients confined and isolated in three hospital areas and N95 respirators used in addition to goggles, gowns, and gloves, as well as liberal use of gel-alcohol hand sanitizer — no more health care workers had influenza-like illness, although 26 additional workers received oseltamivir for 5 days because of varied respiratory symptoms.
Discussion
This case series of the first 18 patients hospitalized in Mexico City with S-OIV infection documents the clinical findings of severe illness or death associated with S-OIV infection that were seen during the beginning of the S-OIV pandemic. The patients, most of them previously healthy, had an influenza-like illness that progressed during a period of 5 to 7 days, had pneumonia, and had findings during the first day of hospital admission that fulfilled the criteria of acute lung injury or the acute respiratory distress syndrome.12 Seven patients died, all from multiorgan system failure. The most consistent laboratory characteristics were increased lactate dehydrogenase level, a total leukocyte count within normal limits, lymphopenia,13 and increased creatine kinase level, most likely due to myositis (or myocardial ischemia, in one patient).
The patients described were part of an epidemic of influenza-like illness with pneumonia seen at our institution and other Mexican hospitals, and only a fraction of them tested positive for S-OIV. A false negative test in patients who had infection with S-OIV would be more likely if the test were delayed or if patients had limited viral shedding. In general, patients who tested negative for S-OIV had a milder clinical course than those who tested positive but were as much a part of the burden of the epidemic as those who were not tested.
Risk factors for severe S-OIV illness are still unknown, but most of our patients were young to middle-aged and had previously been healthy. The majority of the S-OIV infections reported in other countries have been mild, influenza-like illnesses.2 Mexico has also reported a large number of persons with mild disease, through the national surveillance system for influenza, but the full spectrum of clinical illness has not been determined. Other countries will probably report more severe infections as the pandemic spreads and the number of infected persons increases. One contributing factor for death in our patients may have been delayed admission and delayed initiation of oseltamivir. For seasonal influenza, the elderly and young children are at higher risk for severe disease; however, more than half of our patients were between 13 and 47 years of age, which was similar to the age distribution reported in national data of H1N1 infections in Mexico.6 During the 1918 pandemic, a large number of deaths were associated with bacterial infection,14 but concurrent bacterial infection does not appear to be a major contributing factor to the severity of illness in our patients, possibly in part because most received antibiotics before hospitalization.
Mortality among the patients requiring mechanical ventilation was 58%, and although four patients had nosocomial pneumonia, in most of our patients, lung damage was most likely due to the primary effect of infection with influenza virus. Possible mechanisms of damage include direct injury to the respiratory epithelium15 with a secondary cytokine storm. We do not currently know whether our patients, especially those who died, had viremia, as was reported in association with H5N1 infection, a very aggressive variety of influenza.13,16-18 Coinfection with other respiratory viruses could also explain the increased pathogenicity among our patients19,20; however, no other common respiratory viruses were found in our patients. Only three of the patients had received influenza vaccine in fall 2009, since most patients were within the age groups for which vaccine was not recommended in Mexico. It is currently unknown whether seasonal vaccination offered any protection against S-OIV infection, however. We did not find a factor that, before the onset of illness, predicted a worse outcome or death among our patients.
Since 2000, the WHO has prompted countries to prepare for a potential influenza pandemic. In Mexico, pandemic influenza planning began in 2001. Activities included the introduction of yearly influenza vaccination and a program to develop the country's national vaccine production. In 2006, a strategic reserve of oseltamivir, antibiotics, and protective items for health care personnel was established. This reserve is the source of the oseltamivir prescribed to our patients and to most hospitalized patients in Mexico. The experience in our institution highlights the need to reinforce precautions and use of personal protective equipment to prevent the infection of health care workers.
In conclusion, S-OIV infection can cause serious illness and death in young, previously healthy persons. Future studies should identify predictive factors for severe disease and, especially, the effectiveness of early oseltamivir treatment and protection offered by having undergone seasonal influenza vaccination.
No potential conflict of interest relevant to this article was reported.
This article (10.1056/NEJMoa0904252) was published on June 29, 2009, at NEJM.org.
We thank Celia Alpuche, M.D., from the Mexican national reference laboratory (Instituto Nacional de Referencia Epidemiologica); the CDC for providing training and primers for the real-time RT-PCR assay for the swine influenza; the Canadian National Microbiology Laboratory; Michelle Weinberg for careful review of a draft of the manuscript; and all the patients and the personnel of INER who cared for them.
Source Information
From the National Institute of Respiratory Diseases (INER) (R.P.-P., D.R.-Z., F.Q.-F., E.B., A.R.-V., J.R.-S., C.E.O., A.C., A.H., E.M.), Biologicals and Reactives of Mexico (BIRMEX) (S.P.L.), and the Secretariat of Health (M.H., J.A.C.-V.) — all in Mexico City.
Address reprint requests to Dr. Perez-Padilla at Instituto Nacional de Enfermedades Respiratorias, Tlalpan 4502, 14080 Mexico, or at perezpad@gmail.com.
Members of the INER Working Group on Influenza are listed in the Appendix.
Appendix
Members of the INER Working Group on Influenza were the following: J. Rodriguez, M. Barrales, L. Reveles, M.A. Sanchez-Mecatl, D. Ibarra, L.E. Leon, T. Gutierrez, D. Rodriguez-Parga (Emergency Room); C. Aguilar, F. Rocha, I. Serna, V. Huizar, B. Castañeda, J.G. Garcia (Intensive Care); J.L. Sandoval, R. Hernandez, F. Flores, L. Amaya, C. Espinoza (Influenza Ward); E. Sada, G. Reyes-Teran, J. Romo (Infectious Diseases); A. Osorio, E. Sevilla (Hospital Epidemiology); A. Alejandre (Pediatric Pulmonology); S. Rodriguez-Filigrana, J. Chavarria (Medical Direction); R. Fernandez, C. Garcia-Sancho, F. Franco, L. Alfaro-Ramos, J. Godinez-Zavala, L. Martinez (Epidemiology); L. Damian (Nursing); R. Garcia-Torrentera (Respiratory Care); R. Sotelo, L.F. Alba (Chest Imaging); M.E. Vazquez, E. Peña (Pathology); M. Selman-Lama, M.E. Manjarrez, J. Zuñiga (Research Unit); A. Diaz, C. Mora, F. Fernandez, F. de Jesus Contreras, J.P. Villaloz, S. Romero (postgraduate students and residents).
- References
References
1
Swine influenza A (H1N1) infection in two children -- Southern California, March-April 2009. MMWR Morb Mortal Wkly Rep 2009;58:400-402
Medline2
Update: infections with a swine-origin influenza A (H1N1) virus -- United States and other countries, April 28, 2009. MMWR Morb Mortal Wkly Rep 2009;58:431-433
Medline3
Update: swine influenza A (H1N1) infections -- California and Texas, April 2009. MMWR Morb Mortal Wkly Rep 2009;58:435-437
Medline4
Novel Swine-Origin Influenza A (H1N1) Virus Investigation TeamEmergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009;360:2605-2615
Full Text | Web of Science | Medline5
Influenza A (H1N1) — update 14. Geneva: World Health Organization, 2009. (Accessed July 20, 2009, at http://www.who.int/csr/don/2009_05_04a/en/index.html.)
6
Brote de Influenza Humana a H1N1 México Dirección General Adjunta de Epidemiología. Dirección General Adjunta de Epidemiología, 2009. (Accessed July 20, 2009, at http://portal.salud.gob.mx/contenidos/noticias/influenza/estadisticas.html.)
7
CDC protocol of realtime RTPCR for influenza A (H1N1). Geneva: World Health Organization, April 2009. (Accessed July 20, 2009, at http://www.who.int/csr/resources/publications/swineflu/CDCRealtimeRTPCR_SwineH1Assay-2009_20090430.pdf.)
8
Stata statistical software: release 9.0. College Station, TX: StataCorp LP, 2005.
9
Knaus WA ,Draper EA ,Wagner DP ,Zimmerman JE . APACHE II: a severity of disease classification system. Crit Care Med 1985;13:818-829
CrossRef | Web of Science | Medline10
Vincent JL ,Moreno R ,Takala J , et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med 1996;22:707-710
CrossRef | Web of Science | Medline11
Qureshi NR ,Hien TT ,Farrar J ,Gleeson FV . The radiologic manifestations of H5N1 avian influenza. J Thorac Imaging 2006;21:259-264
CrossRef | Web of Science | Medline12
Murray JF ,Matthay MA ,Luce JM ,Flick MR . An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 1988;138:720-723[Erratum, Am Rev Respir Dis 1989;139:1065.]
Web of Science | Medline13
Hui DS . Review of clinical symptoms and spectrum in humans with influenza A/H5N1 infection. Respirology 2008;13:Suppl 1:S10-S13
CrossRef | Web of Science | Medline14
Morens DM ,Taubenberger JK ,Fauci AS . Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. J Infect Dis 2008;198:962-970
CrossRef | Web of Science | Medline15
Ng WF ,To KF ,Lam WW ,Ng TK ,Lee KC . The comparative pathology of severe acute respiratory syndrome and avian influenza A subtype H5N1 -- a review. Hum Pathol 2006;37:381-390
CrossRef | Web of Science | Medline16
Yu H ,Gao Z ,Feng Z , et al. Clinical characteristics of 26 human cases of highly pathogenic avian influenza A (H5N1) virus infection in China. PLoS One 2008;3:e2985-e2985
CrossRef | Web of Science | Medline17
Wong SS ,Yuen KY . Avian influenza virus infections in humans. Chest 2006;129:156-168
CrossRef | Web of Science | Medline18
de Jong MD ,Hien TT . Avian influenza A (H5N1). J Clin Virol 2006;35:2-13
CrossRef | Web of Science | Medline19
Merler S ,Poletti P ,Ajelli M ,Caprile B ,Manfredi P . Coinfection can trigger multiple pandemic waves. J Theor Biol 2008;254:499-507
CrossRef | Web of Science | Medline20
Aberle JH ,Aberle SW ,Pracher E ,Hutter HP ,Kundi M ,Popow-Kraupp T . Single versus dual respiratory virus infections in hospitalized infants: impact on clinical course of disease and interferon-gamma response. Pediatr Infect Dis J 2005;24:605-610
CrossRef | Web of Science | Medline
- Citing Articles (321)
Citing Articles
1
Chompunuch Boonarkart, Ratapum Champunot, Mongkol Uiprasertkul, Charatdao Bunthi, Sumalee Kiatboobsri, Mana Rochanawutanon, Suchat Porncharoenpong, Ornpreya Suptawiwat, Prasert Auewarakul. (2012) Case report: Increased viral receptor expression associated with high viral load and severe pneumonia in a young patient infected with 2009 H1N1 influenza a with no pre-existing conditions. Journal of Medical Virology 84:3, 380-385
CrossRef2
Christian Grieser, Anton Goldmann, Ingo G. Steffen, Marc Kastrup, Carmen María Pérez Fernández, Ulrike Engert, Maria Deja, Christian Lojewski, Timm Denecke. (2012) Computed tomography findings from patients with ARDS due to Influenza A (H1N1) virus-associated pneumonia. European Journal of Radiology 81:2, 389-394
CrossRef3
Curtis L. Cooper. (2012) Pandemic H1N12009 influenza and HIV. Current Opinion in Infectious Diseases 25:1, 26-35
CrossRef4
Ye Liu, Hong Chen, Yajiao Sun, Fuhui Chen. (2012) Antiviral role of toll-like receptors and cytokines against the new 2009 H1N1 virus infection. Molecular Biology Reports 39:2, 1163-1172
CrossRef5
Hendrik Poeck, Jürgen Ruland. (2012) From virus to inflammation: Mechanisms of RIG-I-induced IL-1β production. European Journal of Cell Biology 91:1, 59-64
CrossRef6
J. M. Pereira, R. P. Moreno, R. Matos, A. Rhodes, I. Martin-Loeches, M. Cecconi, T. Lisboa, J. Rello, . (2012) Severity assessment tools in ICU patients with 2009 Influenza A (H1N1) pneumonia. Clinical Microbiology and Infectionno-no
CrossRef7
Peter J. Papadakos, Marcin Karcz, David Schwaiberger, Burkhard Lachmann. (2012) Lungs in Critical Care: New Look at Old Practices. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 79:1, 116-122
CrossRef8
Noriko Nakajima, Yuko Sato, Harutaka Katano, Hideki Hasegawa, Toshio Kumasaka, Satoru Hata, Shinya Tanaka, Tomonori Amano, Takahiko Kasai, Ja-Mun Chong, Toshihiko Iiduka, Iwao Nakazato, Yohko Hino, Akihiko Hamamatsu, Hisashi Horiguchi, Tomoyuki Tanaka, Akio Hasagawa, Yoshiaki Kanaya, Reiko Oku, Takeshi Oya, Tetsutaro Sata. (2012) Histopathological and immunohistochemical findings of 20 autopsy cases with 2009 H1N1 virus infection. Modern Pathology 25:1, 1-13
CrossRef9
Ryotaro Igusa, Tomohiro Sakakibara, Taizo Shibahara, Kazuhiro Sakamoto, Hidekazu Nishimura, Kozo Ota. (2012) Complicated Secondary Pneumonia after Swine-Origin Influenza A Virus Infection in an Immunocompetent Patient. The Tohoku Journal of Experimental Medicine 226:2, 117-120
CrossRef10
E. Cordero, P. Pérez-Romero, A. Moreno, O. Len, M. Montejo, E. Vidal, P. Martín-Dávila, M. C. Fariñas, N. Fernández-Sabé, M. Giannella, J. Pachón, . (2012) Pandemic influenza A(H1N1) virus infection in solid organ transplant recipients: impact of viral and non-viral co-infection. Clinical Microbiology and Infection 18:1, 67-73
CrossRef11
Kyung Sun Park, Tae Sung Park, Jin Tae Suh, You Sun Nam, Mi Suk Lee, Hee Joo Lee. (2012) Characteristics of Outpatients with Pandemic H1N1/09 Influenza in a Tertiary Care University Hospital in Korea. Yonsei Medical Journal 53:1, 213
CrossRef12
A.M. Quispe-Laime, C. Fiore, M.N. González-Ros, J.E. Bettini, V.E. Rolfo, C.G. Campagne, P.A. Barberio. (2012) Capacidad de difusión pulmonar y calidad de vida a los 6 meses del alta de la unidad de cuidados intensivos en sobrevivientes a síndrome de distrés respiratorio agudo por influenza A H1N1. Medicina Intensiva 36:1, 15-23
CrossRef13
N. Nin, C. Sánchez-Rodríguez, L.S. Ver, P. Cardinal, A. Ferruelo, L. Soto, A. Deicas, N. Campos, O. Rocha, D.H. Ceraso, M. El-Assar, J. Ortín, P. Fernández-Segoviano, A. Esteban, J.A. Lorente. (2012) Lung histopathological findings in fatal pandemic influenza A (H1N1). Medicina Intensiva 36:1, 24-31
CrossRef14
Anastasia Antonopoulou, Fotini Baziaka, Thomas Tsaganos, Maria Raftogiannis, Pantelis Koutoukas, Aikaterini Spyridaki, Maria Mouktaroudi, Antigone Kotsaki, Athina Savva, Marianna Georgitsi, Evangelos J. Giamarellos-Bourboulis. (2012) Role of tumor necrosis factor gene single nucleotide polymorphisms in the natural course of 2009 influenza A H1N1 virus infection. International Journal of Infectious Diseases
CrossRef15
Emili Diaz, Ignacio Martin-Loeches, Laura Canadell, Loreto Vidaur, David Suarez, Lorenzo Socias, Angel Estella, Bernardo Gil Rueda, José Eugenio Guerrero, Montserrat Valverdú-Vidal, Juan Carlos Vergara, María Jesús López-Pueyo, Mónica Magret, Teresa Recio, Diego López, Jordi Rello, Alejandro Rodriguez. (2012) Corticosteroid therapy in patients with primary viral pneumonia due to pandemic (H1N1) 2009 influenza. Journal of Infection
CrossRef16
A. Rodríguez, L. Álvarez-Rocha, J.M. Sirvent, R. Zaragoza, M. Nieto, A. Arenzana, P. Luque, L. Socías, M. Martín, D. Navarro, J. Camarena, L. Lorente, S. Trefler, L. Vidaur, J. Solé-Violán, F. Barcenilla, A. Pobo, J. Vallés, C. Ferri, I. Martín-Loeches, E. Díaz, D. López, M.J. López-Pueyo, F. Gordo, F. del Nogal, A. Marqués, S. Tormo, M.P. Fuset, F. Pérez, J. Bonastre, B. Suberviola, E. Navas, C. León. (2012) Recomendaciones del Grupo de Trabajo Enfermedades Infecciosas (GTEI) de la Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias (SEMICYUC) y el Grupo de Estudio de Infecciones en el Paciente Crítico (GEIPC) de la Sociedad Española de Enfermedades Infecciosas y Microbiología clínica (SEIMC) para el diagnóstico y tratamiento de la gripe A/H1N1 en pacientes adultos graves hospitalizados en las Unidades de Cuidados Intensivos. Medicina Intensiva
CrossRef17
Nobuyuki Tanaka, Takuya Emoto, Hiroki Suda, Yoshie Kunihiro, Naofumi Matsunaga, Shunji Hasegawa, Takashi Ichiyama. (2011) High-resolution computed tomography findings of influenza virus pneumonia: a comparative study between seasonal and novel (H1N1) influenza virus pneumonia. Japanese Journal of Radiology
CrossRef18
A. Mady, O.S. Ramadan, A. Yousef, Y. Mandourah, A.A. Amr, M. Kherallah. (2011) Clinical experience with severe 2009 H1N1 influenza in the intensive care unit at King Saud Medical City, Saudi Arabia. Journal of Infection and Public Health
CrossRef19
Sanford R. Kimmel. (2011) The Course and Management of the 2009 H1N1 Pandemic Influenza. Primary Care: Clinics in Office Practice 38:4, 693-701
CrossRef20
Dirk Pabst, Joachim Kuehn, Susanne Schuler-Luettmann, Karsten Wiebe, Pia Lebiedz. (2011) Acute Respiratory Distress Syndrome as a presenting manifestation in young patients infected with H1N1 influenza virus. European Journal of Internal Medicine 22:6, e119-e124
CrossRef21
Soo Ah Im, Hyo Lim Kim, Jong-seo Yoon, Jin Han Kang, Joon-Sung Lee, Ho Jong Chun. (2011) Swine-origin influenza A viral (H1N1) infection in children: chest computed tomography findings. Japanese Journal of Radiology 29:10, 707-711
CrossRef22
Kentaro Yamada, Hiroshi Shinmoto, Manabu Hamamoto, Yusuke Yoshida, Toshio Kawauchi, Tatsumi Kaji, Shigeru Kosuda. (2011) Pneumonia induced by swine-origin influenza A (H1N1) infection: chest computed tomography findings in children. Japanese Journal of Radiology 29:10, 712-717
CrossRef23
Edson Marchiori, Gláucia Zanetti, Cristina Asvolinsque Pantaleão Fontes, Maria Lúcia Oliveira Santos, Paulo Marcos Valiante, Cláudia Mauro Mano, Graça Helena Canto Teixeira, Bruno Hochhegger. (2011) Influenza A (H1N1) virus-associated pneumonia: High-resolution computed tomography–pathologic correlation. European Journal of Radiology 80:3, e500-e504
CrossRef24
Socorro Fernández, Alberto Pérez-Rubio, Jose María Eiros Bouza, Jose Javier Castrodeza Sanz. (2011) Análisis de los casos graves confirmados de gripe en la primera temporada tras la pandemia. Medicina Clínica
CrossRef25
Massimiliano Fabbiani, Michela Sali, Valentina Di Cristo, Giulia Pignataro, Valentina Prete, Salvatore Farina, Alessandro D'Avino, Stefania Manzara, Lorenzo Zileri dal Verme, Nicolò Gentiloni Silveri, Roberto Cauda, Giovanni Delogu, Giovanni Fadda, Simona Di Giambenedetto. (2011) Prospective evaluation of epidemiological, clinical, and microbiological features of pandemic influenza A (H1N1) virus infection in Italy. Journal of Medical Virology 83:12, 2057-2065
CrossRef26
Yeo Hyang Kim, Jung-Eun Kim, Myung Chul Hyun. (2011) Cytokine response in pediatric patients with pandemic influenza H1N1 2009 virus infection and pneumonia: Comparison with pediatric pneumonia without H1N1 2009 infection. Pediatric Pulmonology 46:12, 1233-1239
CrossRef27
Paungpaga Lertdumrongluk, Siribha Changsirikulchai, Chutatip Limkunakul, Poonsuk Prachukthum, Prapaipun Punpiput, Rungtiva Buppanharun, Chuencheevit Chotpitayasunondh. (2011) Safety and immunogenicity of a 2009 influenza A (H1N1) vaccine in hemodialysis patients. Vaccine
CrossRef28
Insung Ahn, Hyeon Seok Son. (2011) Evolutionary analysis of human-origin influenza A virus (H3N2) genes associated with the codon usage patterns since 1993. Virus Genes
CrossRef29
Teresa del Rosal, Fernando Baquero-Artigao, Cristina Calvo, María J. Mellado, Juan C. Molina, María del Mar Santos, María J. Cilleruelo, Mercedes Bueno, Pilar Storch de Gracia, Covadonga Terol, Miguel Á. Roa, Roi Piñeiro, Milagros García López-Hortelano, María L. García-García, Sonia Rodríguez, María Penín, Alejandro Zarauza, Francisco Alvarado, Ana de Blas, Enrique Otheo, Alfonso Rodríguez, María L. Herreros, Alfredo Tagarro, Luis Grande, José T. Ramos, Irene Maté, Cristina Muñoz, Miguel Á. Zafra, María P. Romero-Gómez, Elia Pérez-Fernández, Alberto Delgado, Inmaculada Casas, María E. Cabezas. (2011) Pandemic H1N1 influenza-associated hospitalizations in children in Madrid, Spain. Influenza and Other Respiratory Viruses 5:6, e544-e551
CrossRef30
R Rihani, W Hayajneh, I Sultan, L Ghatasheh, F Abdel-Rahman, N Hussein, A Hussein, A Al-Zaben, M Sarhan, M Saad. (2011) Infections with the 2009 H1N1 influenza virus among hematopoietic SCT recipients: a single center experience. Bone Marrow Transplantation 46:11, 1430-1436
CrossRef31
Ping Li, Dong-Ju Su, Ji-Feng Zhang, Xu-Dong Xia, Hong Sui, Dong-Hui Zhao. (2011) Pneumonia in novel swine-origin influenza A (H1N1) virus infection: High-resolution CT findings. European Journal of Radiology 80:2, e146-e152
CrossRef32
Ulises Angeles-Garay, José A. Gayosso Rivera, Yazmín Zacate-Palacios, Miguel Rechy-Luna, Juan J. Terrazas Estrada, Rafael Arias-Flores. (2011) Características y contagiosidad de influenza A(H1N1) y estacional en trabajadores sanitarios y pacientes de un hospital en la ciudad de México. Enfermedades Infecciosas y Microbiología Clínica 29:9, 679-682
CrossRef33
Arianne B. van Gageldonk-Lafeber, Mariëtte Hooiveld, Adam Meijer, Gé A. Donker, Marie-José Veldman-Ariesen, Wim van der Hoek, Marianne A. B. van der Sande. (2011) The relative clinical impact of 2009 pandemic influenza A (H1N1) in the community compared to seasonal influenza in the Netherlands was most marked among 5-14 year olds. Influenza and Other Respiratory Viruses 5:6, e513-e520
CrossRef34
Helena C. Maltezou, Athanassios Tsakris. (2011) Vaccination of health-care workers against influenza: our obligation to protect patients. Influenza and Other Respiratory Viruses 5:6, 382-388
CrossRef35
Mingli Fang, Min Wan, Sheng Guo, Ran Sun, Ming Yang, TieSuo Zhao, Youyou Yan, Yongsheng Zhang, Wenhui Huang, Xiuli Wu, Yongli Yu, Liying Wang, Shucheng Hua. (2011) An oligodeoxynucleotide capable of lessening acute lung inflammatory injury in mice infected by influenza virus. Biochemical and Biophysical Research Communications 415:2, 342-347
CrossRef36
Joaquín Zúñiga, Martha Torres, Javier Romo, Diana Torres, Luis Jiménez, Gustavo Ramírez, Alfredo Cruz, Enrique Espinosa, Teresa Herrera, Ivette Buendía, Alejandra Ramírez-Venegas, Yolanda González, Karen Bobadilla, Fernando Hernández, Jorge García, Francisco Quiñones-Falconi, Eduardo Sada, María E. Manjarrez, Carlos Cabello, Simón Kawa, Albert Zlotnik, Annie Pardo, Moisés Selman. (2011) Inflammatory profiles in severe pneumonia associated with the pandemic influenza A/H1N1 virus isolated in Mexico City. Autoimmunity 44:7, 562-570
CrossRef37
Leticia Elizondo-Montemayor, Mario M. Alvarez, Martín Hernández-Torre, Patricia A. Ugalde-Casas, Lorena Lam-Franco, Humberto Bustamante-Careaga, Fernando Castilleja-Leal, Julio Contreras-Castillo, Héctor Moreno-Sánchez, Daniela Tamargo-Barrera, Felipe López-Pacheco, Pamela J. Freiden, Stacey Schultz-Cherry. (2011) Seroprevalence of antibodies to influenza A/H1N1/2009 among transmission risk groups after the second wave in Mexico, by a virus-free ELISA method. International Journal of Infectious Diseases 15:11, e781-e786
CrossRef38
Shin Ahn, Won Young Kim, Sung-Han Kim, SangBum Hong, Chae-Man Lim, YounSuck Koh, Kyung Soo Lim, Won Kim. (2011) Role of procalcitonin and C-reactive protein in differentiation of mixed bacterial infection from 2009 H1N1 viral pneumonia. Influenza and Other Respiratory Viruses 5:6, 398-403
CrossRef39
Joon Y. Song, Hee J. Cheong, Jung Y. Heo, Ji Y. Noh, Hwan S. Yong, Yoon K. Kim, Eun Y. Kang, Won S. Choi, Yu M. Jo, Woo J. Kim. (2011) Clinical, laboratory and radiologic characteristics of 2009 pandemic influenza A/H1N1 pneumonia: primary influenza pneumonia versus concomitant/secondary bacterial pneumonia. Influenza and Other Respiratory Viruses 5:6, e535-e543
CrossRef40
D. Roll, J. Ammer, B. Holler, B. Salzberger, B. Schweiger, W. Jilg, R. Andreesen, M. Edinger, D. Wolff, E. Holler. (2011) Vaccination against pandemic H1N1 (2009) in patients after allogeneic hematopoietic stem cell transplantation: a retrospective analysis. Infection
CrossRef41
T. Valente, F. Lassandro, M. Marino, F. Squillante, M. Aliperta, R. Muto. (2011) H1N1 pneumonia: our experience in 50 patients with a severe clinical course of novel swine-origin influenza A (H1N1) virus (S-OIV). La radiologia medica
CrossRef42
N. Buchbinder, C. Dumesnil, D. Pinquier, V. Merle, B. Filhon, P. Schneider, J.P. Vannier. (2011) Pandemic A/H1N1/2009 influenza in a paediatric haematology and oncology unit: successful management of a sudden outbreak. Journal of Hospital Infection 79:2, 155-160
CrossRef43
Zubaida Al-Ismaili, Melissa Piccioni, Michael Zappitelli. (2011) Rhabdomyolysis: pathogenesis of renal injury and management. Pediatric Nephrology 26:10, 1781-1788
CrossRef44
Mabrouk Bahloul, Anis Chaari, Najla Ben Algia, Kamilia Chtara, Hassen Dammak, Chokri Ben Hamida, Hatem Kallel, Hedi Chelly, Mounir Bouaziz. (2011) A literature review of respiratory failure following influenza A (H1N1) virus infection in pregnant and postpartum women. Trends in Anaesthesia and Critical Care 1:5-6, 252-256
CrossRef45
Hernando Sala, Jaime Segovia Roca, Cecilia Zerbo, Rodrigo Garcia, Graciela Cabral, Alejandra Fernandez, Carlos Tummino, Matias Baldini, Oscar Rizzo. (2011) Initial Clinical Management of Symptomatic Adult Patients during Influenza A (H1N1) Epidemics. The Journal of Emergency Medicine 41:4, 435-440
CrossRef46
Anika Singanayagam, Aran Singanayagam, Victoria Wood, James D. Chalmers. (2011) Factors associated with severe illness in pandemic 2009 influenza a (H1N1) infection: Implications for triage in primary and secondary care. Journal of Infection 63:4, 243-251
CrossRef47
Jung Sook Yeom, Ji Sook Park, Ji-Hyun Seo, Eun Sil Park, Jae-Young Lim, Chan-Hoo Park, Hyang-Ok Woo, Hee-Shang Youn, Jae Min Cho. (2011) Factors associated with hypoxemia in children infected with pandemic H1N1 2009 influenza virus. Pediatrics International 53:5, 622-625
CrossRef48
Hidetoshi Ishigaki, Shuji Sai, Masami Shirai, Teruaki Hongo. (2011) Critical findings of severe influenza A (H1N1) pneumonia in children. Pediatrics International 53:5, 669-671
CrossRef49
C. N. J. CAMPBELL, O. T. MYTTON, E. M. McLEAN, P. D. RUTTER, R. G. PEBODY, N. SACHEDINA, P. J. WHITE, C. HAWKINS, B. EVANS, P. A. WAIGHT, J. ELLIS, A. BERMINGHAM, L. J. DONALDSON, M. CATCHPOLE. (2011) Hospitalization in two waves of pandemic influenza A(H1N1) in England. Epidemiology and Infection 139:10, 1560-1569
CrossRef50
Julie Considine, Ramon Z Shaban, Jennifer Patrick, Kerri Holzhauser, Peter Aitken, Michele Clark, Elaine Fielding, Gerry FitzGerald. (2011) Pandemic (H1N1) 2009 Influenza in Australia: Absenteeism and redeployment of emergency medicine and nursing staff. Emergency Medicine Australasia 23:5, 615-623
CrossRef51
Day-Yu Chao, Kuang-Fu Cheng, Tsai-Chung Li, Trong-Neng Wu, Chiu-Ying Chen, Chen-An Tsai, Jin-Hua Chen, Hsien-Tsai Chiu, Jang-Jih Lu, Mei-Chi Su, Yu-Hsin Liao, Wei-Cheng Chan, Ying-Hen Hsieh. (2011) Factors associated with infection by 2009 pandemic H1N1 influenza virus during different phases of the epidemic. International Journal of Infectious Diseases 15:10, e695-e701
CrossRef52
Mabrouk Bahloul, Anis Chaari, Mohamed Samet, Kamilia Chtara, Imen Ben Rejab, Hassen Dammak, Mounir Bouaziz. (2011) Pulmonary capillary leak syndrome following influenza A (H1N1) virus infection in pregnant and postpartum women. Journal of Infection 63:4, 317-319
CrossRef53
Guillaume Lefevre, Jean-Christophe Ianotto, Adrian Tempescul, Philippe Lemoine, Gaelle Guillerm, Christian Berthou. (2011) Infection by H1N1 flu virus revealing T-cell acute lymphoid leukaemia: about two cases. Annals of Hematology 90:9, 1111-1112
CrossRef54
Laura Viviani, Baroukh M. Assael, Eitan Kerem. (2011) Impact of the A (H1N1) pandemic influenza (season 2009–2010) on patients with cystic fibrosis. Journal of Cystic Fibrosis 10:5, 370-376
CrossRef55
Kristopher T. Kahle, Brian P. Walcott, Brian V. Nahed, Zachary R. Barnard, Eng H. Lo, Ferdinando S. Buonanno, Nagagopal Venna, MingMing Ning. (2011) Cerebral edema and a transtentorial brain herniation syndrome associated with pandemic swine influenza A (H1N1) virus infection. Journal of Clinical Neuroscience 18:9, 1245-1248
CrossRef56
S. Reyes, B. Montull, R. Martínez, J. Córdoba, J.M. Molina, V. Martí, A. Martínez, P. Ramírez, R. Menéndez. (2011) Risk factors of A/H1N1 etiology in pneumonia and its impact on mortality. Respiratory Medicine 105:9, 1404-1411
CrossRef57
Huanliang Yang, Yan Chen, Jianzhong Shi, Jing Guo, Xiaoguang Xin, Jian Zhang, Dayan Wang, Yuelong Shu, Chuanling Qiao, Hualan Chen. (2011) Reassortant H1N1 influenza virus vaccines protect pigs against pandemic H1N1 influenza virus and H1N2 swine influenza virus challenge. Veterinary Microbiology 152:3-4, 229-234
CrossRef58
Arnold S. Monto, Steven Black, Stanley A. Plotkin, Walter A. Orenstein. (2011) Response to the 2009 pandemic: Effect on influenza control in wealthy and poor countries. Vaccine 29:38, 6427-6431
CrossRef59
Ifeanyichukwu O. Okike, Chee Yung, Shamez Ladhani, Clarissa Oeser, Aisleen Bennett, Katja Doerholt, Sharon Storey, Sheila Donaghy, Nigel Butter, Katja Hoschler, Liz Sheasby, Paul T. Heath, Elizabeth Miller. (2011) The immunogenicity of a novel A (H1N1) vaccine in HIV-infected children. Vaccine 29:38, 6636-6640
CrossRef60
Rossella Sgarbanti, Lucia Nencioni, Donatella Amatore, Paolo Coluccio, Alessandra Fraternale, Patrizio Sale, Caterina L. Mammola, Guido Carpino, Eugenio Gaudio, Mauro Magnani, Maria R. Ciriolo, Enrico Garaci, Anna Teresa Palamara. (2011) Redox Regulation of the Influenza Hemagglutinin Maturation Process: A New Cell-Mediated Strategy for Anti-Influenza Therapy. Antioxidants & Redox Signaling 15:3, 593-606
CrossRef61
Inmaculada Pinilla, Milagros Martí de Gracia, Manuel Quintana-Díaz, Juan Carlos Figueira. (2011) Radiological prognostic factors in patients with pandemic H1N1 (pH1N1) infection requiring hospital admission. Emergency Radiology 18:4, 313-319
CrossRef62
Mark H Yudin. (2011) Optimizing knowledge of antiviral medications for prophylaxis and treatment of influenza during pregnancy. Expert Review of Respiratory Medicine 5:4, 495-501
CrossRef63
M. Coppola, A. Porto, D. Santo, S. Fronzo, R. Grassi, A. Rotondo. (2011) Influenza A virus: radiological and clinical findings of patients hospitalised for pandemic H1N1 influenza. La radiologia medica 116:5, 706-719
CrossRef64
E. J. B. Veldhuis Kroeze, G. van Amerongen, M. L. Dijkshoorn, J. H. Simon, L. de Waal, I. J. C. Hartmann, G. P. Krestin, T. Kuiken, A. D. M. E. Osterhaus, K. J. Stittelaar. (2011) Pulmonary pathology of pandemic influenza A/H1N1 virus (2009)-infected ferrets upon longitudinal evaluation by computed tomography. Journal of General Virology 92:8, 1854-1858
CrossRef65
Yong-xin Ru, Yue-chuan Li, Yong Zhao, Shi-xuan Zhao, Jing-Ping Yang, Hua-Mei Zhang, Tian-Xiang Pang. (2011) Multiple Organ Invasion by Viruses: Pathological Characteristics in Three Fatal Cases of the 2009 Pandemic Influenza A/H1N1. Ultrastructural Pathology 35:4, 155-161
CrossRef66
Timothy L. Wiemken, Julio A. Ramirez, Philip Polgreen, Paula Peyrani, Ruth M. Carrico. (2011) Evaluation of the knowledge-sharing social network of hospital-based infection preventionists in Kentucky. American Journal of Infection Control
CrossRef67
Gal Dubnov-Raz, Raz Somech, Yaniv Warschawski, Gilad Eisenberg, Yoram Bujanover. (2011) Clinical characteristics of children with 2009 pandemic H1N1 influenza virus infections. Pediatrics International 53:4, 426-430
CrossRef68
Rodica Gilca, Gaston De Serres, Nicole Boulianne, Najwa Ouhoummane, Jesse Papenburg, Monique Douville-Fradet, Élise Fortin, Marc Dionne, Guy Boivin, Danuta M. Skowronski. (2011) Risk factors for hospitalization and severe outcomes of 2009 pandemic H1N1 influenza in Quebec, Canada. Influenza and Other Respiratory Viruses 5:4, 247-255
CrossRef69
David A. Turner, Walter L. Williford, Michelle A. Peters, Janice J. Thalman, Ian R. Shearer, Richard J. Walczak, Michael Griffis, Steven A. Olson, Kevin W. Sowers, Joseph A. Govert, Neil R. MacIntyre, Ira M. Cheifetz. (2011) Development of a collaborative program to provide extracorporeal membrane oxygenation for adults with refractory hypoxemia within the framework of a pandemic*. Pediatric Critical Care Medicine 12:4, 426-430
CrossRef70
Andrew Will, Eleni Tholouli. (2011) The clinical management of tumour lysis syndrome in haematological malignancies. British Journal of Haematology 154:1, 3-13
CrossRef71
Brian J. Minnema, Mehul Patel, Coleman Rotstein, Tony Mazzulli, Susy Hota, Edward H. Cole, Eberhard L. Renner, Heather J. Ross, Lianne G. Singer, Shahid Husain. (2011) Comparison of Hospitalized Solid Organ Transplant Recipients and Nonimmunocompromised Patients With Pandemic H1N1 Infection: A Retrospective Cohort Study. Transplantation 92:2, 230-234
CrossRef72
Ross Blank, Lena M. Napolitano. (2011) Epidemiology of ARDS and ALI. Critical Care Clinics 27:3, 439-458
CrossRef73
L. Moreno Parrado, M.D. Sola-Morena, F.T. Pagán Nuñez, M. Hernández Sansalvador, E. Simarro Córdoba, E.M. García-Martínez. (2011) Estudio descriptivo de los pacientes hospitalizados tratados con oseltamivir. Farmacia Hospitalaria 35:4, 220-222
CrossRef74
Andrés Antón, Tomás Pumarola. (2011) Influenza in immunocompromised patients: considerations for therapy. Future Virology 6:7, 855-868
CrossRef75
Teluguakula Narasaraju, Edwin Yang, Ramar Perumal Samy, Huey Hian Ng, Wee Peng Poh, Audrey-Ann Liew, Meng Chee Phoon, Nico van Rooijen, Vincent T. Chow. (2011) Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis. The American Journal of Pathology 179:1, 199-210
CrossRef76
M. Vilà de Muga, N. Torre Monmany, S. Asensio Carretero, F.J. Travería Casanovas, A. Martínez Mejías, M.T. Coll Sibina, C. Luaces Cubells. (2011) Características clínicas de la gripe A H1N1 2009: estudio multicéntrico. Anales de Pediatría 75:1, 6-12
CrossRef77
S. Laperche. (2011) Definition of emerging infectious diseases. ISBT Science Series 6:1, 112-115
CrossRef78
Magda Abd Elsalam Ahmed, Nabil Jergis Awadalla, Abdel baset Mohamed Saleh. (2011) Clinical epidemiology comparison of H1N1 RT-PCR-positive and RT-PCR-negative pneumonia during the 2009-2010 pandemic in Mansoura University Hospitals, Egypt. Influenza and Other Respiratory Viruses 5:4, 241-246
CrossRef79
Saori Sakabe, Makoto Ozawa, Ryo Takano, Kiyoko Iwastuki-Horimoto, Yoshihiro Kawaoka. (2011) Mutations in PA, NP, and HA of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice. Virus Research 158:1-2, 124-129
CrossRef80
Koji Takayama, Jin Kuramochi, Takeshi Oinuma, Hiromi Kaneko, Satoshi Kurasawa, Makito Yasui, Kaori Okayasu, Hiroshi Ono, Naohiko Inase. (2011) Clinical features of the 2009 swine-origin influenza A (H1N1) outbreak in Japan. Journal of Infection and Chemotherapy 17:3, 401-406
CrossRef81
Qiuyan Liao, Benjamin J. Cowling, Wendy Wing Tak Lam, Richard Fielding. (2011) The Influence of Social-Cognitive Factors on Personal Hygiene Practices to Protect Against Influenzas: Using Modelling to Compare Avian A/H5N1 and 2009 Pandemic A/H1N1 Influenzas in Hong Kong. International Journal of Behavioral Medicine 18:2, 93-104
CrossRef82
Su Young Kim, Jeung Sook Kim, Chan Sup Park. (2011) Various computed tomography findings of 2009 H1N1 influenza in 17 patients with relatively mild illness. Japanese Journal of Radiology 29:5, 301-306
CrossRef83
Min Hyok Jeon, Jin-Won Chung, Seong-Ho Choi, Tae Hyong Kim, Eun Jung Lee, Eun Ju Choo. (2011) Pneumonia risk factors and clinical features of hospitalized patients older than 15 years with pandemic influenza A (H1N1) in South Korea: a multicenter study. Diagnostic Microbiology and Infectious Disease 70:2, 230-235
CrossRef84
M. Miluy Guerrero, M. Ruiz Campuzano, J.J. Hernández Roca, M.C. Alcántara Zafra. (2011) Repercusión hospitalaria de la pandemia por gripe A H1N1 en 2009 en un Área de Salud de la Región de Murcia. Revista Clínica Española 211:6, 320-321
CrossRef85
S. H. Torun, A. Somer, N. Salman, M. Ciblak, D. Demirkol, M. Kanturvardar, S. Badur, O. Devecioglu. (2011) Clinical and Epidemiological Characteristics of Pandemic Influenza A/(H1N1) in Hospitalized Pediatric Patients at a University Hospital, Istanbul, Turkey. Journal of Tropical Pediatrics 57:3, 213-216
CrossRef86
M. Bray, J. Lawler, J. Paragas, P. B. Jahrling, D. J. Mollura. (2011) Molecular Imaging of Influenza and Other Emerging Respiratory Viral Infections. Journal of Infectious Diseases 203:10, 1348-1359
CrossRef87
Enrique Maraví-Poma, Ignacio Martin-Loeches, Eva Regidor, Clara Laplaza, Koldo Cambra, Sara Aldunate, Jose Eugenio Guerrero, Ana Loza-Vazquez, Elena Arnau, Jordi Almirall, Leonardo Lorente, Angel Arenzana, Monica Magret, Roberto Reig Valero, Enrique Marquez, Nagore Gonzalez, Jesús Francisco Bermejo-Martin, Jordi Rello. (2011) Severe 2009 A/H1N1v influenza in pregnant women in Spain*. Critical Care Medicine 39:5, 945-951
CrossRef88
B. -A. Gaüzère, F. Bussienne, B. Bouchet, J. Jabot, A. Roussiaux, D. Drouet, S. Djourhi, B. Leauté, D. Belcour, G. Bossard, S. Champion, M. -C. Jaffar-Bandjee, O. Belmonte, P. Vilain, E. Brottet, L. Hoang, D. Vandroux. (2011) Formes graves d’infection par le virus A(H1N1)v2009 à La Réunion en 2009 et en 2010. Bulletin de la Société de pathologie exotique 104:2, 97-104
CrossRef89
M. Lagrange-Xélot, B. Kuli, M. -C. Jaffar, E. Chirpaz, M. -P. Moiton. (2011) Épidémie de grippe A(H1N1)2009 à La Réunion: expérience de la consultation ambulatoire dédiée, juillet–septembre 2009. Bulletin de la Société de pathologie exotique 104:2, 142-146
CrossRef90
Masaru Terai, Takafumi Honda, Shiho Yamamoto, Masaki Yoshida, Nozomi Tsuchiya, Yoko Moriyama, Takuya Matsui, Shoko Tokutake, Emiyu Suzuki, Yuri Shirato, Ayako Muto, Kitami Hayashi, Hiromichi Hamada. (2011) Early induction of interleukin-5 and peripheral eosinophilia in acute pneumonia in Japanese children infected by pandemic 2009 influenza A in the Tokyo area. Microbiology and Immunology 55:5, 341-346
CrossRef91
Silvio A. Ñamendys-Silva, Carolina Pérez-Jiménez, Patricia Cornejo-Juárez, Diana Vilar-Compte, Patricia Volkow. (2011) Prolonged lymphopenia in a patient with lymphoma and severe Pandemic influenza A H1N1 2009 virus infection. Influenza and Other Respiratory Viruses 5:3, 167-169
CrossRef92
A. Rodríguez, I. Martin-Loeches, J. Bonastre, P. Olaechea, F. Álvarez-Lerma, R. Zaragoza, J. Guerrero, J. Blanco, F. Gordo, F. Pozo, J. Lorente, J. Carratalá, M. Cordero, J. Rello, A. Esteban, C. León. (2011) First influenza season after the 2009 pandemic influenza: report of the first 300 ICU admissions in Spain. Medicina Intensiva 35:4, 208-216
CrossRef93
N. Nin, J. A. Lorente, L. Soto, F. Ríos, J. Hurtado, F. Arancibia, S. Ugarte, E. Echevarría, P. Cardinal, F. Saldarini, H. Bagnulo, I. Cortés, G. Bujedo, C. Ortega, F. Frutos, A. Esteban. (2011) Acute kidney injury in critically ill patients with 2009 influenza A (H1N1) viral pneumonia: an observational study. Intensive Care Medicine 37:5, 768-774
CrossRef94
Sergio T. Fanella, Michelle A. Pinto, Natalie A. Bridger, Jared M. P. Bullard, Jennifer M. L. Coombs, Maryanne E. Crockett, Karen L. Olekson, Philippe G. Poliquin, Paul G. Van Caeseele, Joanne E. Embree. (2011) Pandemic (H1N1) 2009 Influenza in Hospitalized Children in Manitoba: Nosocomial Transmission and Lessons Learned from the First Wave. Infection Control and Hospital Epidemiology 32:5, 435-443
CrossRef95
D. Viasus, J. R. Paño-Pardo, J. Pachón, A. Campins, F. López-Medrano, A. Villoslada, M. C. Fariñas, A. Moreno, J. Rodríguez-Baño, J. A. Oteo, J. Martínez-Montauti, J. Torre-Cisneros, F. Segura, F. Gudiol, J. Carratalà, . (2011) Factors associated with severe disease in hospitalized adults with pandemic (H1N1) 2009 in Spain. Clinical Microbiology and Infection 17:5, 738-746
CrossRef96
Gabriele Neumann, Yoshihiro Kawaoka. (2011) The first influenza pandemic of the new millennium. Influenza and Other Respiratory Viruses 5:3, 157-166
CrossRef97
A. Rodriguez, E. Diaz, I. Martin-Loeches, A. Sandiumenge, L. Canadell, J. J. Diaz, J. C. Figueira, A. Marques, F. Alvarez-Lerma, J. Valles, B. Baladin, F. Garcia-Lopez, B. Suberviola, R. Zaragoza, S. Trefler, J. Bonastre, J. Blanquer, J. Rello, , P. Cobo, J. Martins, C. Carbayo, E. Robles-Musso, A. Cardenas, J. Fierro, D. O. Fernandez, R. Sierra, M. {a. } Jesus Huertos, J. Carlos Pozo, R. Guerrero, E. Marquez, M. Rodriguez-Carvajal, A. Jareno, J. Pomares, J. L. Ballesteros, Y. Fernandez, F. Lobato, J. F. Prieto, J. Albofedo-Sanchez, P. Martinez, M. A. Diaz Castellanos, G. Sevilla, J. Garnacho-Montero, R. Hinojosa, E. Fernandez, A. Loza, C. Leon, A. Arenzana, D. Ocana, I. Navarrete, M. Zaheri Beryanaki, I. Sanchez, M. L. Avellanas, A. Lander, S. G. Ramirez de Arellano, M. I. Marquina Lacueva, P. Luque, I. Gonzalez, J. M. {a. } Monton, P. Dorado Regil, L. Iglesias, C. Pascual Gonzalez, Quiroga, A. Garcia-Rodriguez, L. Socias, P. Ibanez, M. Borges-Sa, A. Socias, A. Del Castillo, R. Jorda Marcos, J. M. Bonell, I. Amestaran, S. Ruiz-Santana, J. J. Diaz, Sison, D. Hernandez, A. Trujillo, L. Regalado, L. Lorente, M. Martin, S. Martinez, J. J. Caceres, B. Suberviola, P. Ugarte, F. Garcia-Lopez, A. Alvaro Alonso, A. Pasilla, M. {a. } L. Gomez Grande, A. Albaya, A. Canabal, L. Marina, A. Simon, J. Maria Anon, J. B. Lopez Messa, M. {a. } J. Lopez Pueyo, Z. Ferreras, S. Macias, J. Angel Berezo, J. B. Varela, A. A. Ojeda, A. A. Terrero, F. Tena Ezpeleta, Z. Paez, A. Garcia, R. M. {a. } Catalan, M. Ferrer, A. Torres, S. Barbadillo, L. Cabre, A. Rovira, F. Alvarez-Lerma, A. Vazquez, J. Nolla, F. Fernandez, J. R. Cervello, R. Manez, J. Ballus, R. M. {a. } Granada, J. Valles, M. Ortiz, C. Guia, F. Armestar, J. Paez, J. Almirall, X. Balanzo, J. Rello, E. Arnau, L. Llopart, M. Palomar, I. Catalan, J. M. {a. } Sirvent, C. Ferri, N. L. de Arbina, M. Badia, M. Valverdu-Vidal, F. Barcenilla, M. Magret, M. F. Esteban, J. Luna, J. M. {a. } Nava, J. G. de Molina, Z. Josic, F. Gurri, A. Rodriguez, T. Lisboa, D. de Mendoza, S. Trefler, R. Maria Diaz, E. Mesalles, J.-N. Jose, A. Fernandez-Zapata, T. Recio, A. Arrascaeta, M. {a. } J. Garcia-Ramos, E. Gallego, F. Bueno, M. Diaz, M. {a. } L. Cordero, J. A. Pastor, L. Alvarez-Rocha, D. Vila, A. D. Lamas, J. B. Perez, M. Ortiz Piquer, E. Merayo, V. J. Lopez-Ciudad, J. Cortez, E. Vilaboy, E. M. Saborido, R. J. Gonzalez, S. Freita, A. M. Lopez, J. Canabal, E. Ferres, J. L. Monzon, F. Goni, F. Del Nogal Saez, M. Blasco Navalpotro, M. {a. } C. Garcia-Torrejon, C. Perez-Calvo, D. Lopez, L. Arnaiz, S. Sanchez-Alonso, C. Velayos, F. del Rio, M. A. Gonzalez, M. C. Martin, J. M. {a. } Molina, J. C. Montejo, M. Catalan, P. Albert, A. de Pablo, J. E. Guerrero, J. B. Peyrat, E. Cerda, M. Alvarez, C. Pey, M. Rodriguez, E. Palencia, R. Caballero, C. Vaquero, F. Mariscal, S. Garcia, N. Carrasco, I. Prieto, A. Lietor, R. Ramos, B. Galvan, J. C. Figueira, M. C. Soriano, P. Galdos, B. Balandin Moreno, F. del Cabo, C. Hermosa, F. Gordo, A. Algora, A. Paredes, J. A. Cambronero, S. Gomez-Rosado, L. M. Prado Lopez, S. Martinez, F. F. Abad, M. Martinez, S. M. Buti, B. Gil Rueda, F. Garcia, L. Macaya, E. Maravi-Poma, I. Jimenez Urra, L. Macaya Redin, A. Telleria, J. Insansti, N. Gonzalez, P. Marco, L. Vidaur, B. Santamaria, J. C. Vergara, J. R. Iruretagoyena Amiano, A. Manzano, C. C. Arenal, P. M. Olaechea, J. Blanquer, R. Reig Valero, A. Belenger, S. Altaba, B. Alvarez-Sanchez, S. Alberto Picos, A. Sanchez-Miralles, J. Bonastre, M. Palamo, J. Cebrian, J. Cunat, B. Romero, R. Zaragoza, V. Paricio, A. Marques, S. Sanchez-Morcillo, S. Tormo, J. Latour, M. Angel Garcia, A. Ribas. (2011) Impact of early oseltamivir treatment on outcome in critically ill patients with 2009 pandemic influenza A. Journal of Antimicrobial Chemotherapy 66:5, 1140-1149
CrossRef98
Ville Pettilä, Steven A. R. Webb, Michael Bailey, Belinda Howe, Ian M. Seppelt, Rinaldo Bellomo. (2011) Acute kidney injury in patients with influenza A (H1N1) 2009. Intensive Care Medicine 37:5, 763-767
CrossRef99
Selman Unverdi, Hatice Akay, Mevlut Ceri, Salih Inal, Mustafa Altay, Ali Pekcan Demiroz, Murat Duranay. (2011) Acute Kidney Injury due to Rhabdomyolysis in H1N1 Influenza Infection. Renal Failure 33:4, 450-451
CrossRef100
Raquel Martin-Iguacel, Piergiorgio Bresil, Peter Stubbe Teglbjærg, Jasmina Huremovic. (2011) Acute Myositis With Prolonged Hyperthermia After Severe Influenza A (H1N1) Pneumonia in 2 Obese Patients. Infectious Diseases in Clinical Practice 19:3, 223-225
CrossRef101
Juan Ledesma, Francisco Pozo, Mercedes Pérez Ruiz, Jose María Navarro, Luis Piñeiro, Milagros Montes, Sonia Pérez Castro, Jonathan Suárez Fernández, Juan García Costa, Mirian Fernández, Juan Carlos Galán, María Teresa Cuevas, Inmaculada Casas, Pilar Pérez Breña. (2011) Substitutions in position 222 of haemagglutinin of pandemic influenza A (H1N1) 2009 viruses in Spain. Journal of Clinical Virology 51:1, 75-78
CrossRef102
Eva Montané, Josep Lecumberri, María Luisa Pedro-Botet. (2011) Gripe A, embarazo y antivíricos inhibidores de la neuraminidasa. Medicina Clínica 136:15, 688-693
CrossRef103
Paula Garland, Hugues de Lavallade, Takuya Sekine, Katja Hoschler, Shiranee Sriskandan, Parind Patel, Stephen Brett, Kate Stringaris, Eva Loucaides, Katherine Howe, David Marin, Ed Kanfer, Nichola Cooper, Donald Macdonald, Amin Rahemtulla, Mark Atkins, Akila Danga, Dragana Milojkovic, Ian Gabriel, Ahmad Khoder, Abdullah Alsuliman, Jane Apperley, Katayoun Rezvani. (2011) Humoral and Cellular Immunity to Primary H1N1 Infection in Patients with Hematologic Malignancies following Stem Cell Transplantation. Biology of Blood and Marrow Transplantation 17:5, 632-639
CrossRef104
Nicolás Nin, José A. Lorente, Carolina Sánchez-Rodríguez, Rosario Granados, Lorena S. Ver, Luis Soto, Jefferson Hidalgo, Pilar Fernández-Segoviano, Juan Ortín, Andrés Esteban. (2011) Kidney histopathological findings in fatal pandemic 2009 influenza A (H1N1). Intensive Care Medicine 37:5, 880-881
CrossRef105
Jorge S. Sasbón, Mónica A. Centeno, Mauro D. García, Nancy B. Boada, Bettina E. Lattini, Eduardo A. Motto, Marcela A. Zuázaga, Viviana V. Acebedo, Martín E. Truszkowski, Silvia Filippini. (2011) Influenza A (pH1N1) infection in children admitted to a pediatric intensive care unit: Differences with other respiratory viruses*. Pediatric Critical Care Medicine 12:3, e136-e140
CrossRef106
Massimiliano Fabbiani, Simona Di Giambenedetto, Michela Sali, Salvatore Farina, Paola Sansonetti, Enrica Tamburrini, Lorenzo Zileri Dal Verme, Giovanni Delogu, Andrea De Luca, David Kelvin, Roberto Cauda, Giovanni Fadda. (2011) Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients. Vaccine 29:16, 2836-2839
CrossRef107
Luis Espinosa-Aguilar, Jaime S. Green, Graeme N. Forrest, Edward D. Ball, Richard T. Maziarz, Lynne Strasfeld, Randy Allison Taplitz. (2011) Novel H1N1 Influenza in Hematopoietic Stem Cell Transplantation Recipients: Two Centers’ Experiences. Biology of Blood and Marrow Transplantation 17:4, 566-573
CrossRef108
B. D. Gupta, A. Purohit. (2011) A Clinical Study of Hospitalized H1N1 Infected Children in Western Rajasthan. Journal of Tropical Pediatrics 57:2, 87-90
CrossRef109
Takafumi Okada, Miyuki Morozumi, Keita Matsubara, Osamu Komiyama, Kimiko Ubukata, Takashi Takahashi, Satoshi Iwata. (2011) Characteristic findings of pediatric inpatients with pandemic (H1N1) 2009 virus infection among severe and nonsevere illnesses. Journal of Infection and Chemotherapy 17:2, 238-245
CrossRef110
E Martínez, MA Marcos, I Hoyo-Ulloa, A Antón, M Sánchez, A Vilella, M Larrousse, I Pérez, A Moreno, A Trilla, T Pumarola, JM Gatell. (2011) Influenza A H1N1 in HIV-infected adults*. HIV Medicine 12:4, 236-245
CrossRef111
Isaac I Bogoch, Jason R Andrews, Francisco M Marty, Elizabeth L Hohmann. (2011) HIV-1 and 2009 H1N1 Influenza A in Adults. JAIDS Journal of Acquired Immune Deficiency Syndromes 56:4, e111-e113
CrossRef112
S.-Y. Yoo, J.H. Kim, H. Eo, T.Y. Jeon, K.E. Shin, W.S. Shin, H.N. Jung, Y.-J. Kim. (2011) H1N1 influenza infection in children: Frequency, pattern, and outcome of chest radiographic abnormalities. Clinical Radiology 66:4, 334-339
CrossRef113
B Mohty, Y Thomas, M Vukicevic, M Nagy, E Levrat, M Bernimoulin, L Kaiser, E Roosnek, J Passweg, Y Chalandon. (2011) Clinical features and outcome of 2009-influenza A (H1N1) after allogeneic hematopoietic SCT. Bone Marrow Transplantation
CrossRef114
A. R. Iverson, K. L. Boyd, J. L. McAuley, L. R. Plano, M. E. Hart, J. A. McCullers. (2011) Influenza Virus Primes Mice for Pneumonia From Staphylococcus aureus. Journal of Infectious Diseases 203:6, 880-888
CrossRef115
S. A. Truelove, A. S. Chitnis, R. T. Heffernan, A. E. Karon, T. E. Haupt, J. P. Davis. (2011) Comparison of Patients Hospitalized With Pandemic 2009 Influenza A (H1N1) Virus Infection During the First Two Pandemic Waves in Wisconsin. Journal of Infectious Diseases 203:6, 828-837
CrossRef116
Brian J. Burns, Karel Habig, Cliff Reid, Paul Kernick, Chris Wilkinson, Gary Tall, Sarah Coombes, Ron Manning. (2011) Logistics and Safety of Extracorporeal Membrane Oxygenation in Medical Retrieval. Prehospital Emergency Care 15:2, 246-253
CrossRef117
Andreu Comas-García, Christian A. García-Sepúlveda, José J. Méndez-de Lira, Saray Aranda-Romo, Alba E. Hernández-Salinas, Daniel E. Noyola. (2011) Mortality attributable to pandemic influenza A (H1N1) 2009 in San Luis Potosí, Mexico. Influenza and Other Respiratory Viruses 5:2, 76-82
CrossRef118
Pritesh Patel, Veena Nandwani, John Vanchiere, Steven A. Conrad, L. Keith Scott. (2011) Use of therapeutic plasma exchange as a rescue therapy in 2009 pH1N1 influenza A—An associated respiratory failure and hemodynamic shock. Pediatric Critical Care Medicine 12:2, e87-e89
CrossRef119
Aysegul Zenciroglu, Ahmet Afsin Kundak, Mustafa Aydin, Nurullah Okumus, Arzu Dursun, Mehmet Sah Ipek, Belma Saygılı Karagol, Nilay Hakan, Nazmiye Nilgun Karadag, Ayse Basak Altas, Gulay Korukluoglu. (2011) Swine influenza A (H1N1) virus infection in infants. European Journal of Pediatrics 170:3, 333-338
CrossRef120
Georg Gdynia, Paul Schnitzler, Eva Brunner, Reinhard Kandolf, Hendrik Bläker, Edith Daum, Philipp Schnabel, Peter Schirmacher, Wilfried Roth. (2011) Sudden death of an immunocompetent young adult caused by novel (swine origin) influenza A/H1N1-associated myocarditis. Virchows Archiv 458:3, 371-376
CrossRef121
F. J. O Brien, S. D. Jairam, C. A. Traynor, C. M. Kennedy, M. Power, M. D. Denton, C. Magee, P. J. Conlon. (2011) Pandemic H1N1 (2009) and renal failure: the experience of the Irish national tertiary referral centre. Irish Journal of Medical Science 180:1, 135-138
CrossRef122
Lior Goldberg, David Greenberg, Itay Zelcer, Leonel Slanovic, Yonat Shemer-Avni, Ronit Nativ, Avraham Borer, Gabriel Hodik, Michael Sherf, Matitiahu Lifshitz, Eugene Leibovitz. (2011) EPIDEMIOLOGIC, CLINICAL, LABORATORY, AND THERAPEUTIC CHARACTERISTICS OF INFLUENZA A/H1N1 IN MOSLEM BEDOUIN AND JEWISH CHILDREN HOSPITALIZED IN SOUTHERN ISRAEL DURING 2009. The Pediatric Infectious Disease Journal1
CrossRef123
Yuejie Zheng, Yanxia He, Jikui Deng, Zhiwei Lu, Jurong Wei, Weiguo Yang, Zhengzhen Tang, Boning Li, Jaosheng Zhang, Li Wang, Hui Zhao, Xiaonan Li, Zhenzhu Yu, Ping Song, Yijiao Ma, Yingfei Li, Chengrong Li. (2011) Hospitalized children with 2009 influenza a (H1N1) infection in Shenzhen, China, november-december 2009. Pediatric Pulmonology 46:3, 246-252
CrossRef124
A S Hollister, W P Sheridan. (2011) The Emergency Use Authorization of Peramivir IV: A View from the Manufacturer. Clinical Pharmacology & Therapeutics 89:2, 172-174
CrossRef125
Hirokazu Ezoe, Yukihiro Akeda, Zhenyu Piao, Taiki Aoshi, Shohei Koyama, Takeshi Tanimoto, Ken J. Ishii, Kazunori Oishi. (2011) Intranasal vaccination with pneumococcal surface protein A plus poly(I:C) protects against secondary pneumococcal pneumonia in mice. Vaccine 29:9, 1754-1761
CrossRef126
M. Daudé, J.M. Mansuy, J. Guitard, G. Basse, L. Esposito, J. Izopet, L. Rostaing, N. Kamar. (2011) Influenza A (H1N1) virus-induced hepatocellular injury in a kidney transplant patient. Transplant Infectious Disease 13:1, 70-72
CrossRef127
H. Seale, R. Kaur, Q. Wang, P. Yang, Y. Zhang, X. Wang, X. Li, H. Zhang, Z. Zhang, C.R. MacIntyre. (2011) Acceptance of a vaccine against pandemic influenza A (H1N1) virus amongst healthcare workers in Beijing, China. Vaccine 29:8, 1605-1610
CrossRef128
Jan A. Wiegand, Christian Torgersen, Stefan Bloechlinger, Jukka Takala, Martin W. Dünser. (2011) Influenza A(H1N1) infection and severe cardiac dysfunction in adults: A case series. Wiener klinische Wochenschrift 123:3-4, 120-123
CrossRef129
Tacettin Örnek, Funda Demirtaş Yalçın, Selami Ekin, Şaban Yalçın, Mücahit Yemişen. (2011) Pneumonia in patients with novel influenza A (H1N1) virus in Southeastern Turkey. Wiener klinische Wochenschrift 123:3-4, 106-111
CrossRef130
Clare Ramsey, Anand Kumar. (2011) H1N1: viral pneumonia as a cause of acute respiratory distress syndrome. Current Opinion in Critical Care 17:1, 64-71
CrossRef131
M. Bassetti, A. Parisini, A. Calzi, F. M. Bobbio Pallavicini, G. Cassola, S. Artioli, M. Anselmo, G. Pagano, G. Rezza, C. Viscoli, . (2011) Risk factors for severe complications of the novel influenza A (H1N1): analysis of patients hospitalized in Italy. Clinical Microbiology and Infection 17:2, 247-250
CrossRef132
Ana Clara Monsalvo, Juan P Batalle, M Florencia Lopez, Jens C Krause, Jennifer Klemenc, Johanna Zea Hernandez, Bernardo Maskin, Jimena Bugna, Carlos Rubinstein, Leandro Aguilar, Liliana Dalurzo, Romina Libster, Vilma Savy, Elsa Baumeister, Liliana Aguilar, Graciela Cabral, Julia Font, Liliana Solari, Kevin P Weller, Joyce Johnson, Marcela Echavarria, Kathryn M Edwards, James D Chappell, James E Crowe, John V Williams, Guillermina A Melendi, Fernando P Polack. (2011) Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes. Nature Medicine 17:2, 195-199
CrossRef133
P Theerawit, Y Sutherasan, T Hongpanat, C Kiatboonsri, S Kiatboonsri. (2011) Hemodynamic and echocardiographic characteristics in severe novel influenza A (H1N1) pneumonia. Critical Care 15:Suppl 1, P223
CrossRef134
Tristan W Clark, Daniel H Fleet, Martin J Wiselka. (2011) Severe community-acquired adenovirus pneumonia in an immunocompetent 44-year-old woman: a case report and review of the literature. Journal of Medical Case Reports 5:1, 259
CrossRef135
Ji Eun Kim, Siegfried Bauer, Kyong Suk La, Kee Hyoung Lee, Ji Tae Choung, Kyoung Ho Roh, Chang Kyu Lee, Young Yoo. (2011) CD4+/CD8+ T lymphocytes imbalance in children with severe 2009 pandemic influenza A (H1N1) pneumonia. Korean Journal of Pediatrics 54:5, 207
CrossRef136
Rianne AB van Gageldonk-Lafeber, Rob M Riesmeijer, Ingrid HM Friesema, Adam Meijer, Leslie D Isken, Aura Timen, Marianne AB van der Sande. (2011) Case-based reported mortality associated with laboratory-confirmed influenza A(H1N1) 2009 virus infection in the Netherlands: the 2009-2010 pandemic season versus the 2010-2011 influenza season. BMC Public Health 11:1, 758
CrossRef137
Y. DENG, X. H. PANG, P. YANG, W. X. SHI, L. L. TIAN, B. W. LIU, S. LI, S. J. CUI, Y. LI, G. L. LU, L. ZHANG, X. ZHANG, B. LIU, H. SEALE, F. HUANG, Q. Y. WANG. (2011) Serological survey of 2009 H1N1 influenza in residents of Beijing, China. Epidemiology and Infection 139:01, 52-58
CrossRef138
Myung Jae Yun, Seong Tae Lee, Hye Jin Oh, Seung June Lee, Sook Hee Song, In Sohn, Jae Phil Choi, Su Hyun Kim. (2011) Clinical Features of Hospitalized Patients with Community Acquired Pneumonia during 2009 Influenza A (H1N1) Pandemic. The Korean Journal of Critical Care Medicine 26:3, 162
CrossRef139
Akira Katsumi, Tetsuya Nishida, Makoto Murata, Seitaro Terakura, Kazuyuki Shimada, Shigeki Saito, Miki Kobayashi, Akari Kodaira, Shinichiro Shibata, Isao Oda, Tetsuya Yagi, Hitoshi Kiyoi, Tadashi Matsushita, Tetsuhito Kojima, Tomoki Naoe. (2011) Virus-Associated Hemophagocytic Syndrome Caused by Pandemic Swine-Origin Influenza A (H1N1) in a Patient After Unrelated Bone Marrow Transplantation. Journal of Clinical and Experimental Hematopathology 51:1, 63-65
CrossRef140
Young Nam Kim, Hwa Jin Cho, Young Kuk Cho, Jae Sook Ma. (2011) Clinical significance of pleural effusion in the new influenza a (H1N1) viral pneumonia in children and adolescent. Pediatric Pulmonologyn/a-n/a
CrossRef141
Woo Hyun Cho, Yun Seong Kim, Doo Soo Jeon, Ji Eun Kim, Kun Il Kim, Hee Yun Seol, Ki Uk Kim, Hye Kyung Park, Min Ki Lee, Soon Kew Park, Yeon Joo Jeong. (2011) Outcome of Pandemic H1N1 Pneumonia: Clinical and Radiological Findings for Severity Assessment. The Korean Journal of Internal Medicine 26:2, 160
CrossRef142
Won Sup Oh, Seung-Joon Lee, Chang-Seop Lee, Ji-An Hur, Ae-Chung Hur, Yoon Seon Park, Sang-Taek Heo, In-Gyu Bae, Sang Won Park, Eu Suk Kim, Hong Bin Kim, Kyoung-Ho Song, Kkot Sil Lee, Sang-Rok Lee, Joon Sup Yeom, Su Jin Lee, Baek-Nam Kim, Yee Gyung Kwak, Jae Hoon Lee, Yong Keun Kim, Hyo Youl Kim, Nam Joong Kim, Myoung-don Oh. (2011) A Prediction Rule to Identify Severe Cases among Adult Patients Hospitalized with Pandemic Influenza A (H1N1) 2009. Journal of Korean Medical Science 26:4, 499
CrossRef143
Gernot Beutel, Olaf Wiesner, Matthias Eder, Carsten Hafer, Andrea S Schneider, Jan T Kielstein, Christian Kühn, Albert Heim, Tina Ganzenmüller, Hans-Heinrich Kreipe, Axel Haverich, Andreas Tecklenburg, Arnold Ganser, Tobias Welte, Marius M Hoeper. (2011) Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Critical Care 15:2, R80
CrossRef144
Kyoko Shinya, Tadashi Okamura, Setsuko Sueta, Noriyuki Kasai, Motoko Tanaka, Teridah E Ginting, Akiko Makino, Amie J Eisfeld, Yoshihiro Kawaoka. (2011) Toll-like receptor pre-stimulation protects mice against lethal infection with highly pathogenic influenza viruses. Virology Journal 8:1, 97
CrossRef145
Marco Ciapetti, Giovanni Cianchi, Giovanni Zagli, Cesare Greco, Andrea Pasquini, Rosario Spina, Stefano Batacchi, Manuela Bonizzoli, Massimo Bonacchi, Chiara Lazzeri, Pasquale Bernardo, Adriano Peris. (2011) Feasibility of inter-hospital transportation using extra-corporeal membrane oxygenation (ECMO) support of patients affected by severe swine-flu(H1N1)-related ARDS. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 19:1, 32
CrossRef146
Elena Chiappini, Luisa Galli, Alberta Azzi, Massimo Resti, Francesca Bonsignori, Maurizio de Martino. (2011) Lymphocytopenia as a marker for pandemic influenza A/H1N1 2009 virus infection in children. Journal of Medical Virology 83:1, 1-4
CrossRef147
Fernando G Ríos, Elisa Estenssoro, Fernando Villarejo, Ricardo Valentini, Liliana Aguilar, Daniel Pezzola, Pascual Valdez, Miguel Blasco, Cristina Orlandi, Javier Alvarez, Fernando Saldarini, Alejandro Gómez, Pablo E Gómez, Martin Deheza, Alan Zazu, Mónica Quinteros, Ariel Chena, Javier Osatnik, Damian Violi, Maria Gonzalez, Guillermo Chiappero. (2011) Lung Function and Organ Dysfunctions in 178 Patients Requiring Mechanical Ventilation During The 2009 Influenza A (H1N1) Pandemic. Critical Care 15:4, R201
CrossRef148
Jin-Kyong Chun, Byung Ho Cha, Young Uh, Hyo Youl Kim, Young Keun Kim, Woocheol Kwon, Hwang Min Kim. (2011) The Association of Lymphopenia with the Clinical Severity in the Korean Children Admitted to the Hospital with Pandemic (H1N1) 2009 Infection. Infection and Chemotherapy 43:1, 36
CrossRef149
Day-Yu Chao, Kuang-Fu Cheng, Ying-Hen Hsieh, Tsai-Chung Li, Trong-Neng Wu, Chiu-Ying Chen, Chen-An Tsai, Jin-Hwa Chen, Hsien-Tsai Chiu, Jang-Jih Lu, Mei-Chi Su, Yu-Hsin Liao. (2011) Serological response and persistence in schoolchildren with high baseline seropositive rate after receiving 2009 pandemic influenza A(H1N1) vaccine. Vaccine 29:4, 617-623
CrossRef150
M. Martí-de-Gracia, I. Pinilla, M. Quintana-Díaz, H. Rodríguez-Requena, C. Prados-Sánchez. (2011) Is H1N1 flu different from seasonal flu on initial plain chest films?. Radiología (English Edition) 53:2, 159-165
CrossRef151
Silvio A. Ñamendys-Silva, María O. González-Herrera, Julia Texcocano-Becerra, Angel Herrera-Gómez. (2011) Acute Respiratory Distress Syndrome Caused by Influenza B Virus Infection in a Patient with Diffuse Large B-Cell Lymphoma. Case Reports in Medicine 2011, 1-4
CrossRef152
Yao-Zhang Huang, Mao-Wei Hsieh, Chien-Hui Hung, Chung-Hua Hsu. (2011) Improved Pulmonary Inflammation and Fibrosis Progression after Influenza A (H1N1) Infection by Chinese Herbal Medicine: A Case Report. ISRN Pulmonology 2011, 1-4
CrossRef153
A. Rodríguez, I. Martin-Loeches, J. Bonastre, P. Olaechea, F. Álvarez-Lerma, R. Zaragoza, J. Guerrero, J. Blanco, F. Gordo, F. Pozo, J. Lorente, J. Carratalá, M. Cordero, J. Rello, A. Esteban, C. León. (2011) First influenza season after the 2009 pandemic influenza: report of the first 300 ICU admissions in Spain. Medicina Intensiva (English Edition) 35:4, 208-216
CrossRef154
Marcia Querci, Martin E. Stryjewski, Fabián Herrera, Elena Temporiti, Wanda Alcalá, Natalia Chavez, Laura Figueras, Fernanda Barberis, Marcela Echavarría, Cristina Videla, Alfredo Martínez, Guadalupe Carballal, Pablo Bonvehí. (2011) Healthcare personnel infected with novel influenza A H1N1 virus in university hospitals in Buenos Aires, Argentina. Scandinavian Journal of Infectious Diseases 43:1, 70-74
CrossRef155
Ignacio Martin-Loeches, Elisabeth Papiol, Alejandro Rodríguez, Emili Diaz, Rafael Zaragoza, Rosa Granada, Lorenzo Socias, Juan Bonastre, Montserrat Valverdú, Juan Pozo, Pilar Luque, Jose Juliá-Narvaéz, Lourdes Cordero, Antonio Albaya, Daniel Serón, Jordi Rello, . (2011) Acute kidney injury in critical ill patients affected by influenza A (H1N1) virus infection. Critical Care 15:1, R66
CrossRef156
Karen EA Burns, Clarence Chant, Orla Smith, Brian Cuthbertson, Robert Fowler, Deborah J Cook, Peter Kruger, Steve Webb, Jamal Alhashemi, Guillermo Dominguez-Cherit, Carlos Zala, Gordon D Rubenfeld, John C Marshall. (2011) A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial. Trials 12:1, 70
CrossRef157
Xiao-Wen Cheng, Juan Lu, Chun-Li Wu, Li-Na Yi, Xu Xie, Xiang-Dong Shi, Shi-Song Fang, Hong Zan, Hsiang-fu Kung, Ming-Liang He. (2011) Three fatal cases of pandemic 2009 influenza A virus infection in Shenzhen are associated with cytokine storm. Respiratory Physiology & Neurobiology 175:1, 185-187
CrossRef158
Michele Iannuzzi, Edoardo De Robertis, Ornella Piazza, Fabio Rispoli, Giuseppe Servillo, Rosalba Tufano. (2011) Respiratory failure presenting in H1N1 influenza with Legionnaires disease: two case reports. Journal of Medical Case Reports 5:1, 520
CrossRef159
Eun Lee, Ju-Hee Seo, Hyung-Young Kim, Shin Na, Sung-Han Kim, Ji-Won Kwon, Byoung-Ju Kim, Soo-Jong Hong. (2011) Clinical characteristics and outcomes among pediatric patients hospitalized with pandemic influenza A/H1N1 2009 infection. Korean Journal of Pediatrics 54:8, 329
CrossRef160
Valeria Trivellin, Vera Gandini, Luigi Nespoli. (2011) Low adherence to influenza vaccination campaigns: is the H1N1 virus pandemic to be blamed?. Italian Journal of Pediatrics 37:1, 54
CrossRef161
Diego López Mendoza, Marcos I. Restrepo. (2011) Severe pandemic H1N1 2009 influenza A infection: Are we ready to move on?. Respirology 16:1, 1-2
CrossRef162
Jun Seong Son, Yee Hyung Kim, Young Kyung Lee, So Young Park, Cheon Woong Choi, Myung Jae Park, Jee-Hong Yoo, Hong Mo Kang, Jong Hoo Lee, Boram Park. (2011) Pandemic Influenza A/H1N1 Viral Pneumonia without Co-Infection in Korea: Chest CT Findings. Tuberculosis and Respiratory Diseases 70:5, 397
CrossRef163
Ignacio MARTIN-LOECHES, Alejandro RODRIGUEZ, Juan BONASTRE, Rafael ZARAGOZA, Rafael SIERRA, Asunción MARQUES, Jose JULIÁ-NARVAEZ, Emili DIAZ, Jordi RELLO, . (2011) Severe pandemic (H1N1)v influenza A infection: Report on the first deaths in Spain. Respirology 16:1, 78-85
CrossRef164
Tadahiko ITOH, Takefumi MATSUDA, Naoshi IWAMA, Daiki KONDO, Masataka INOUE. (2011) Clinical Study of 4 Infantile Cases of a New Type of Influenza of 2009 Complicated by Severe Breathing Difficulty. JOURNAL OF THE JAPANESE ASSOCIATION OF RURAL MEDICINE 59:5, 585-590
CrossRef165
Karina T Timenetsky, Silvia HCT Aquino, Cilene Saghabi, Corinne Taniguchi, Claudia V Silvia, Luci Correa, Alexandre R Marra, Raquel AC Eid, Oscar FP dos Santos. (2011) High success and low mortality rates with non-invasive ventilation in influenza A H1N1 patients in a tertiary hospital. BMC Research Notes 4:1, 375
CrossRef166
Kyung-Yil Lee, Jung-Woo Rhim, Jin-Han Kang. (2011) Hyperactive immune cells (T cells) may be responsible for acute lung injury in influenza virus infections: A need for early immune-modulators for severe cases. Medical Hypotheses 76:1, 64-69
CrossRef167
T. Takano, H. Tajiri, Y. Kashiwagi, S. Kimura, H. Kawashima. (2011) Cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection. European Journal of Clinical Microbiology & Infectious Diseases 30:1, 117-120
CrossRef168
Amreeta Dhanoa, Ngim C Fang, Sharifah S Hassan, Priyatharisni Kaniappan, Ganeswrie Rajasekaram. (2011) Epidemiology and clinical characteristics of hospitalized patients with pandemic influenza A (H1N1) 2009 infections: the effects of bacterial coinfection. Virology Journal 8:1, 501
CrossRef169
Min Jung Kwon, Chang Kyu Lee, Kyoung Ho Roh, Myung Hyun Nam, Soo Young Yoon, Chae Seung Lim, Yun Jung Cho, Young Kee Kim, Kap No Lee. (2011) Clinical Characteristics and Comparison of the Various Methods Used for the Diagnosis of the New Influenza A Pandemic in Korea. Laboratory Medicine Online 1:1, 26
CrossRef170
Predrag Romic, Darko Nozic, Maja Surbatovic, Milic Veljovic, Mihajlo Stojic, Rade Vukovic. (2011) Mechanical ventilation in patients with most severe forms of influenza a H1N1. Vojnosanitetski pregled 68:3, 235-240
CrossRef171
Dragan Mikic, Darko Nozic, Miroslav Kojic, Svetlana Popovic, Dejan Hristovic, Radmila Rajic-Dimitrijevic, Petar Curcic, Milomir Milanovic, Rade Glavatovic, Vesna Begovic-Kupresanin, Milic Veljovic, Dragan Djordjevic, Nada Kuljic-Kapulica, Radovan Cekanac, Dara Stefanovic. (2011) Clinical manifestations, therapy and outcome of pandemic influenza a (H1N1) 2009 in hospitalized patients. Vojnosanitetski pregled 68:3, 248-256
CrossRef172
Ignacio Martin-Loeches, Emili Diaz, Loreto Vidaur, Antoni Torres, Cesar Laborda, Rosa Granada, Juan Bonastre, Mar Martin, Josu Insausti, Angel Arenzana, Jose Eugenio Guerrero, Ines Navarrete, Jesus Bermejo-Martin, David Suarez, Alejandro Rodriguez, . (2011) Pandemic and post-pandemic Influenza A (H1N1) infection in critically ill patients. Critical Care 15:6, R286
CrossRef173
Astrid Smud, Claudia B. Nagel, Elizabeth Madsen, María del C. Rial, Laura A. Barcán, Abel A. Gomez, Andrea G. Martinoia, María C. Bangher, Javier D. Altclas, Claudia C. Salgueira, Elena Temporiti, Pablo E. Bonvehi, Natalia Enriquez, Ernesto D. Efron, Julián E. Bibolini, Roberta Lattes. (2010) Pandemic Influenza A/H1N1 Virus Infection in Solid Organ Transplant Recipients: A Multicenter Study. Transplantation 90:12, 1458-1462
CrossRef174
Tathagat Narula, Mathew Safley, Bennett P. deBoisblanc. (2010) H1N1-Associated Acute Respiratory Distress Syndrome Symbol. The American Journal of the Medical Sciences 340:6, 499-504
CrossRef175
Nizar A. Al-Nakshabandi. (2010) Chest radiographic findings in swine origin influenza A (H1N1) viral infection experienced in a tertiary care university hospital in Saudi Arabia. The Egyptian Journal of Radiology and Nuclear Medicine 41:4, 497-500
CrossRef176
Woolf T Walker, Saul N Faust. (2010) Monovalent inactivated split-virion AS03-adjuvanted pandemic influenza A (H1N1) vaccine. Expert Review of Vaccines 9:12, 1385-1398
CrossRef177
L. A. Hajjar, T. Mauad, F. R. B. G. Galas, A. Kumar, L. F. F. da Silva, M. Dolhnikoff, T. Trielli, J. P. Almeida, M. R. L. Borsato, E. Abdalla, L. Pierrot, R. Kalil Filho, J. O. C. Auler, P. H. N. Saldiva, P. M. Hoff. (2010) Severe novel influenza A (H1N1) infection in cancer patients. Annals of Oncology 21:12, 2333-2341
CrossRef178
J. J. Strouse, M. E. Reller, D. G. Bundy, M. Amoako, M. Cancio, R. N. Han, A. Valsamakis, J. F. Casella. (2010) Severe pandemic H1N1 and seasonal influenza in children and young adults with sickle cell disease. Blood 116:18, 3431-3434
CrossRef179
Fernando Lovato-Salas, Lorena Matienzo-Serment, César Monjarás-Ávila, Elizabeth E. Godoy-Lozano, Andreu Comas-García, Marcela Aguilera-Barragán, Adriana Durham-González, Soledad Contreras-Vidales, Uciel Ochoa-Pérez, Alejandro Gómez-Gómez, Christian A. García-Sepúlveda, Daniel E. Noyola. (2010) Pandemic influenza A(H1N1) 2009 and respiratory syncytial virus associated hospitalizations. Journal of Infection 61:5, 382-390
CrossRef180
João Carlos Winck, Miguel Gonçalves. (2010) H1N1 infection and acute respiratory failure: Can we give non-invasive ventilation a chance?. Revista Portuguesa de Pneumologia (English Edition) 16:6, 907-911
CrossRef181
M. E. Falagas, N. V. Cholevas, A. M. Kapaskelis, E. K. Vouloumanou, A. Michalopoulos, P. I. Rafailidis. (2010) Epidemiological aspects of 2009 H1N1 influenza: the accumulating experience from the Northern Hemisphere. European Journal of Clinical Microbiology & Infectious Diseases 29:11, 1327-1347
CrossRef182
Stephanie G. Norfolk, Caroline L. Hollingsworth, Cameron R. Wolfe, Joseph A. Govert, Loretta G. Que, Ira M. Cheifetz, John W. Hollingsworth. (2010) Rescue therapy in adult and pediatric patients with pH1N1 influenza infection: A tertiary center intensive care unit experience from April to October 2009*. Critical Care Medicine 38:11, 2103-2107
CrossRef183
Chian Yong Low, Terence Kee, Kwai Peng Chan, Lynette L.E. Oon, Chee Kiat Tan, Nancy W.S. Tee, Ban Hock Tan. (2010) Pandemic (H1N1) 2009 Infection in Adult Solid Organ Transplant Recipients in Singapore. Transplantation 90:9, 1016-1021
CrossRef184
Ju-Ying Wei, Fei-Fei Chen, Jie Jin, Wen-Yuan Mai, Wen-Bin Qian, Hai-Tao Meng, Li-Ping Mao, Gai-Xiang Xu, Hua-Feng Wang, Yin-Jun Lou, Hong-Yan Tong. (2010) Novel influenza A (H1N1) in patients with hematologic disease. Leukemia & Lymphoma 51:11, 2079-2083
CrossRef185
Antoine Roch, Renaud Lepaul-Ercole, Dominique Grisoli, Jacques Bessereau, Olivier Brissy, Matthias Castanier, Stephanie Dizier, Jean-Marie Forel, Christophe Guervilly, Vlad Gariboldi, Frederic Collart, Pierre Michelet, Gilles Perrin, Remi Charrel, Laurent Papazian. (2010) Extracorporeal membrane oxygenation for severe influenza A (H1N1) acute respiratory distress syndrome: a prospective observational comparative study. Intensive Care Medicine 36:11, 1899-1905
CrossRef186
Walter R. Hasibeder, Martin W. Dünser, Milad Halabi, Gabriele Brinninger. (2010) The relationship between extravascular lung water and oxygenation in three patients with influenza A (H1N1)-induced respiratory failure. Wiener klinische Wochenschrift 122:21-22, 637-640
CrossRef187
Soo Youn Shin, Joon Hyung Kim, Hyun Su Kim, Young A Kang, Ha Gyung Lee, Jin Seok Kim, Jong-Koo Lee, Woo Kyung Kim. (2010) Clinical characteristics of Korean pediatric patients critically ill with influenza A (H1N1) virus. Pediatric Pulmonology 45:10, 1014-1020
CrossRef188
Kin-Wang To, Sing Lee, Tat-On Chan, Shui-Shan Lee. (2010) Exploring determinants of acceptance of the pandemic influenza A (H1N1) 2009 vaccination in nurses. American Journal of Infection Control 38:8, 623-630
CrossRef189
L.C. Robertson, S.H. Allen, S.P. Konamme, J. Chestnut, P. Wilson. (2010) The successful use of extra-corporeal membrane oxygenation in the management of a pregnant woman with severe H1N1 2009 influenza complicated by pneumonitis and adult respiratory distress syndrome. International Journal of Obstetric Anesthesia 19:4, 443-447
CrossRef190
Melchor Riera, Antoni Payeras, Maria A Marcos, Diego Viasus, Maria C Farinas, Ferran Segura, Julian Torre-Cisneros, Alejandro Martín-Quirós, Jesús Rodríguez-Baño, Juan Vila, Elisa Cordero, Jordi Carratalà. (2010) Clinical presentation and prognosis of the 2009 H1N1 influenza A infection in HIV-1-infected patients: a Spanish multicenter study. AIDS 24:16, 2461-2467
CrossRef191
Peng Yang, Ying Deng, Xinghuo Pang, Weixian Shi, Xinyu Li, Lili Tian, Yi Zhang, Xiaoli Wang, Fang Huang, MacIntyre C. Raina, Quanyi Wang. (2010) Severe, critical and fatal cases of 2009 H1N1 influenza in China. Journal of Infection 61:4, 277-283
CrossRef192
F. Daneschwar, S. Tschudin Sutter, A.F. Widmer, M. Battegay. (2010) 42-jähriger, adipöser Patient mit beatmungspflichtiger H1N1-Infektion. Der Internist 51:10, 1308-1312
CrossRef193
Krow Ampofo, Amy Herbener, Anne J. Blaschke, Caroline Heyrend, Mark Poritz, Kent Korgenski, Robert Rolfs, Seema Jain, Maria da Glória Carvalho, Fabiana C. Pimenta, Judy Daly, Edward O. Mason, Carrie L. Byington, Andrew T. Pavia. (2010) Association of 2009 Pandemic Influenza A (H1N1) Infection and Increased Hospitalization With Parapneumonic Empyema in Children in Utah. The Pediatric Infectious Disease Journal 29:10, 905-909
CrossRef194
P. Sriram, Manish Kumar, R. Renitha, Nivedita Mondal, Vishnu B. Bhat. (2010) Clinical Profile of Swine Flu in Children at Puducherry. The Indian Journal of Pediatrics 77:10, 1093-1095
CrossRef195
Marek J. Slomka, Anstice L. E. Densham, Vivien J. Coward, Steve Essen, Sharon M. Brookes, Richard M. Irvine, Erica Spackman, Jonathan Ridgeon, Rebecca Gardner, Amanda Hanna, David L. Suarez, Ian H. Brown. (2010) Original Article: Real time reverse transcription (RRT)-polymerase chain reaction (PCR) methods for detection of pandemic (H1N1) 2009 influenza virus and European swine influenza A virus infections in pigs. Influenza and Other Respiratory Viruses 4:5, 277-293
CrossRef196
Richard N. van Zyl-Smit, Laurence Brunet, Madhukar Pai, Wing-Wai Yew. (2010) The Convergence of the Global Smoking, COPD, Tuberculosis, HIV, and Respiratory Infection Epidemics. Infectious Disease Clinics of North America 24:3, 693-703
CrossRef197
M. Raftogiannis, A. Antonopoulou, F. Baziaka, A. Spyridaki, P. Koutoukas, T. Tsaganos, A. Savva, A. Pistiki, M. Georgitsi, E. J. Giamarellos-Bourboulis. (2010) Indication for a role of regulatory T cells for the advent of influenza A (H1N1)-related pneumonia. Clinical & Experimental Immunology 161:3, 576-583
CrossRef198
Chakradhar Venkata, Priya Sampathkumar, Bekele Afessa. (2010) Hospitalized Patients With 2009 H1N1 Influenza Infection: The Mayo Clinic Experience. Mayo Clinic Proceedings 85:9, 798-805
CrossRef199
A. C. Argent. (2010) Impact of influenza A/pH1N1 2009 in Canada and elsewhere*. Pediatric Critical Care Medicine 11:5, 637-638
CrossRef200
Julian W. Tang, Nandini Shetty, Tommy T.Y. Lam, K.L. Ellis Hon. (2010) Emerging, Novel, and Known Influenza Virus Infections in Humans. Infectious Disease Clinics of North America 24:3, 603-617
CrossRef201
S. Vernadakis, M. Adamzik, M. Heuer, G. Antoch, H. Baba, M. Fiedler, J. Buer, A. Paul, G.M. Kaiser. (2010) Hemikolektomie bei Kolonischämie. Der Chirurg 81:9, 841-845
CrossRef202
Sean Berryman. (2010) Extracorporeal membrane oxygenation in a Scottish intensive care unit. Nursing in Critical Care 15:5, 262-268
CrossRef203
Christine Korteweg, Jiang Gu. (2010) Pandemic influenza A (H1N1) virus infection and avian influenza A (H5N1) virus infection: a comparative analysisThis paper is one of a selection of papers published in this special issue entitled “Second International Symposium on Recent Advances in Basic, Clinical, and Social Medicine” and has undergone the Journal's usual peer review process.. Biochemistry and Cell Biology 88:4, 575-587
CrossRef204
Barbara Donner, Viswanathan Niranjan, Gerhard Hoffmann. (2010) Safety of Oseltamivir in Pregnancy. Drug Safety 33:8, 631-642
CrossRef205
Jin Soo Shin, Seon Do Hwang, Hyun Soo Kim, Sung Whan Cho, Sang Heui Seo. (2010) Protection of Ferrets from Infection by Swine-Origin 2009 A (H1N1) Influenza Virus by the Inactivated Vaccine. Viral Immunology 23:4, 395-402
CrossRef206
Ina Jeong, Chang-hoon Lee, Deog Kyeom Kim, Hee Soon Chung, Sang Won Park. (2010) Mild form of 2009 H1N1 influenza infection detected by active surveillance: Implications for infection control. American Journal of Infection Control 38:6, 482-485
CrossRef207
José María Navarro-Marí, José María Mayoral-Cortés, Mercedes Pérez-Ruiz, Jesús Rodríguez-Baño, Jordi Carratalá, Virtudes Gallardo-García. (2010) Infección en humanos por virus de la gripe A(H1N1): revisión al 30 de octubre de 2009. Enfermedades Infecciosas y Microbiología Clínica 28:7, 446-452
CrossRef208
Mohammed M. Al Aklabi, Justin G. Weinkauf, Atul Humar, Nitin Ghorpade. (2010) Successful bilateral lung transplantation in a patient with end-stage lung disease and positive novel influenza virus (H1N1). The Journal of Heart and Lung Transplantation 29:8, 898-899
CrossRef209
Brett M. Elicker, Brian S. Schwartz, Catherine Liu, Eunice C. Chen, Steve A. Miller, Charles Y. Chiu, W. Richard Webb. (2010) Thoracic CT findings of novel influenza A (H1N1) infection in immunocompromised patients. Emergency Radiology 17:4, 299-307
CrossRef210
Koji Wada, Hiroshi Nishiura, Akihiko Kawana. (2010) An epidemiological analysis of severe cases of the influenza A (H1N1) 2009 virus infection in Japan. Influenza and Other Respiratory Viruses 4:4, 179-186
CrossRef211
Silvia Vírseda, María Alejandra Restrepo, Elena Arranz, Purificación Magán-Tapia, Mario Fernández-Ruiz, Agustín Gómez de la Cámara, José María Aguado, Francisco López-Medrano. (2010) Seasonal and Pandemic A (H1N1) 2009 influenza vaccination coverage and attitudes among health-care workers in a Spanish University Hospital. Vaccine 28:30, 4751-4757
CrossRef212
Wun-Ju Shieh, Dianna M. Blau, Amy M. Denison, Marlene DeLeon-Carnes, Patricia Adem, Julu Bhatnagar, John Sumner, Lindy Liu, Mitesh Patel, Brigid Batten, Patricia Greer, Tara Jones, Chalanda Smith, Jeanine Bartlett, Jeltley Montague, Elizabeth White, Dominique Rollin, Rongbao Gao, Cynthia Seales, Heather Jost, Maureen Metcalfe, Cynthia S. Goldsmith, Charles Humphrey, Ann Schmitz, Clifton Drew, Christopher Paddock, Timothy M. Uyeki, Sherif R. Zaki. (2010) 2009 Pandemic Influenza A (H1N1). The American Journal of Pathology 177:1, 166-175
CrossRef213
Helena C. Maltezou. (2010) Novel (pandemic) influenza A H1N1 in healthcare facilities: Implications for prevention and control. Scandinavian Journal of Infectious Diseases 42:6-7, 412-420
CrossRef214
Thomas Henzler, Mathias Meyer, Armin Kalenka, Markus Alb, Gerald Schmid-Bindert, Sönke Bartling, Joseph U. Schoepf, Stefan O. Schoenberg, Christian Fink. (2010) Image Findings of Patients with H1N1 Virus Pneumonia and Acute Respiratory Failure. Academic Radiology 17:6, 681-685
CrossRef215
C. Tsigrelis, M. Mohammad, H. S. Fraimow, R. P. Dellinger, D. Marchesani, A. C. Reboli. (2010) Secondary bacterial pneumonia due to Staphylococcus aureus complicating 2009 influenza A (H1N1) viral infection. Infection 38:3, 237-239
CrossRef216
Heather L. Forrest, Robert G. Webster. (2010) Perspectives on influenza evolution and the role of research. Animal Health Research Reviews 11:01, 3-18
CrossRef217
Mireia Cantero Caballero, Ángel Touma Fernández, M. Jesús Granda Martín, Ana Castuera Gil, Paul Zegarra Salas, Carmen Cuenca Carvajal, Juan Carlos Cano Ballesteros, Susana Granado De La Orden, María Ferrer Civeira, Pilar Catalán Alonso, Cristina Pérez Sanz, Ángel Aguaron De La Cruz, Carlos Merello Godino, Juan Andueza Lillo, Paz Rodríguez Pérez, Luis Audibert Mena. (2010) Demanda de atención hospitalaria por gripe A/H1N1: evaluación de los primeros 1.000 casos atendidos. Medicina Clínica 135:1, 1-7
CrossRef218
Julio A. Farias, Analía Fernández, Ezequiel Monteverde, Nilda Vidal, Pilar Arias, María J. Montes, Gabriela Rodríguez, Mariela Allasia, Maria E. Ratto, Roxana Jaén, Claudia Meregalli, Karina Fiquepron, Ana R. Calvo, Alejandro Siaba, Lidia Albano, Rossana Poterala, Pablo Neira, Andrés Esteban. (2010) Critically ill infants and children with influenza A (H1N1) in pediatric intensive care units in Argentina. Intensive Care Medicine 36:6, 1015-1022
CrossRef219
Nigel Eastman, Barbara Philips, Andrew Rhodes. (2010) Triaging for adult critical care in the event of overwhelming need. Intensive Care Medicine 36:6, 1076-1082
CrossRef220
Kelvin Kai-Wang To, Iris Wai-Sum Li, Ivan Fan-Ngai Hung, Vincent Chi-Chung Cheng, Kwok-Yung Yuen. (2010) Pathogenesis of pandemic H1N1 2009 influenza virus infection and the implication on management. Frontiers of Medicine in China 4:2, 147-156
CrossRef221
T. Ganzenmueller, J. Kluba, B. Hilfrich, W. Puppe, W. Verhagen, A. Heim, T. Schulz, C. Henke-Gendo. (2010) Comparison of the performance of direct fluorescent antibody staining, a point-of-care rapid antigen test and virus isolation with that of RT-PCR for the detection of novel 2009 influenza A (H1N1) virus in respiratory specimens. Journal of Medical Microbiology 59:6, 713-717
CrossRef222
E. Busi Rizzi, V. Schininà, F. Ferraro, L. Rovighi, M. Cristoforo, D. Chiappetta, F. Lisena, F. Lauria, C. Bibbolino. (2010) Radiological findings of pneumonia in patients with swine-origin influenza A virus (H1N1). La radiologia medica 115:4, 507-515
CrossRef223
Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza. (2010) Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection. New England Journal of Medicine 362:18, 1708-1719
Full Text224
Matthew E. Falagas, Evridiki K. Vouloumanou, Evagelia Baskouta, Petros I. Rafailidis, Kostantinos Polyzos, Jordi Rello. (2010) Treatment options for 2009 H1N1 influenza: evaluation of the published evidence. International Journal of Antimicrobial Agents 35:5, 421-430
CrossRef225
Guillermo Domínguez-Cherit, Silvio A. Ñamendys-Silva, Alethse Torre, Alejandro E. Macias, Jose Angel Cordova-Villalobos. (2010) H1N1 Influenza Pandemic of 2009 Compared With Other Influenza Pandemics: Epidemiology, Diagnosis, Management, Pulmonary Complications, and Outcomes. Current Infectious Disease Reports 12:3, 204-210
CrossRef226
C. F. N. Koegelenberg, E. M. Irusen, R. Cooper, A. H. Diacon, J. J. Taljaard, A. Mowlana, F. von Groote-Bidlingmaier, C. T. Bolliger. (2010) High mortality from respiratory failure secondary to swine-origin influenza A (H1N1) in South Africa. QJM 103:5, 319-325
CrossRef227
Julian W Tang, Nandini Shetty, Tommy Tsan-Yuk Lam. (2010) Features of the new pandemic influenza A/H1N1/2009 virus: virology, epidemiology, clinical and public health aspects. Current Opinion in Pulmonary Medicine 16:3, 235-241
CrossRef228
Sven Meyer, Corina Ilchmann, Matti Adam, Edgar Sattinger, Dimitrios Siamkouris, Umeswaran Arunagirinathan, Tobias Deuse, Florian M. Wagner, Hermann Reichenspurner, Angelika Costard-Jaeckle. (2010) Asymptomatic infection with novel influenza A/H1N1 virus in a heart transplant recipient. The Journal of Heart and Lung Transplantation 29:5, 585-586
CrossRef229
Aron Flagg, Lara Danziger-Isakov, Charles Foster, Colleen Nasman, Nicholas Smedira, John Carl, Charles Kwon, Stephen Davis, Gerard Boyle. (2010) Novel 2009 H1N1 influenza virus infection requiring extracorporeal membrane oxygenation in a pediatric heart transplant recipient. The Journal of Heart and Lung Transplantation 29:5, 582-584
CrossRef230
Peter Wark. (2010) Viral and bacterial interactions in pneumonia. Expert Review of Respiratory Medicine 4:2, 221-228
CrossRef231
Michael B. Rothberg, Sarah D. Haessler. (2010) Complications of seasonal and pandemic influenza. Critical Care Medicine 38, e91-e97
CrossRef232
Edson Marchiori, Gláucia Zanetti, Bruno Hochhegger, Rosana Souza Rodrigues, Cristina Asvolinsque Pantaleão Fontes, Luiz Felipe Nobre, Alexandre Dias Mançano, Gustavo Meirelles, Klaus Loureiro Irion. (2010) High-resolution computed tomography findings from adult patients with Influenza A (H1N1) virus-associated pneumonia. European Journal of Radiology 74:1, 93-98
CrossRef233
Philippe R. S. Lagacé-Wiens, Ethan Rubinstein, Abba Gumel. (2010) Influenza epidemiology—past, present, and future. Critical Care Medicine 38, e1-e9
CrossRef234
M. Parikh, G. Dolson, V. Ramanathan, W. Sangsiraprapha. (2010) Novel H1N1-associated rhabdomyolysis leading to acute renal failure. Clinical Microbiology and Infection 16:4, 330-332
CrossRef235
Katharine Squires, Andrew Watkins, Kai König. (2010) H1N1 influenza in an extremely premature baby with chronic lung disease. Pediatric Pulmonology 45:4, 409-410
CrossRef236
Jonathan P Wong, Mary E Christopher, Satya Viswanathan, Glen Schnell, Xiaojiang Dai, Donald Van Loon, Eric R Stephen. (2010) Aerosol and nasal delivery of vaccines and antiviral drugs against seasonal and pandemic influenza. Expert Review of Respiratory Medicine 4:2, 171-177
CrossRef237
Stephen E. Lapinsky. (2010) H1N1 novel influenza A in pregnant and immunocompromised patients. Critical Care Medicine 38, e52-e57
CrossRef238
Lena M. Napolitano, Pauline K. Park, Krishnan Raghavendran, Robert H. Bartlett. (2010) Nonventilatory strategies for patients with life-threatening 2009 H1N1 influenza and severe respiratory failure. Critical Care Medicine 38, e74-e90
CrossRef239
Elizabeth L. Daugherty, Richard D. Branson, Asha Deveraux, Lewis Rubinson. (2010) Infection control in mass respiratory failure: Preparing to respond to H1N1. Critical Care Medicine 38, e103-e109
CrossRef240
Anete Trajman, Dick Menzies. (2010) Occupational respiratory infections. Current Opinion in Pulmonary Medicine1
CrossRef241
László Bidiga, László Asztalos, Zoltán Fülep, Béla Fülesdi, Gábor Méhes. (2010) Az új influenzavírus- (H1N1-) fertőzés okozta fatális kimenetelű tüdőgyulladás. Orvosi Hetilap 151:14, 576-579
CrossRef242
B. Inusa, M. Zuckerman, N. Gadong, M. Afif, S. Arnott, P. Heath, G. Marais, P. Robertson, H. Payne, O. Wilkey, D. C. Rees. (2010) Pandemic influenza A (H1N1) virus infections in children with sickle cell disease. Blood 115:11, 2329-2330
CrossRef243
M. Martí-de-Gracia, I. Pinilla, M. Quintana-Díaz, H. Rodríguez-Requena, C. Prados-Sánchez. (2010) Gripe A ¿diferente de la gripe estacional?. Radiología 53:2, 159-165
CrossRef244
J. Torres Macho, C. Martínez-Fidalgo Vázquez, Y. Majo Carbajo, B. Jara Chinarro. (2010) Neumonía grave por gripe A: ¿algún otro responsable?. Revista Clínica Española 210:3, e1-e3
CrossRef245
Andrew R. Lai, Kevin Keet, Celina M. Yong, Janet V. Diaz. (2010) Severe H1N1-Associated Acute Respiratory Distress Syndrome: A Case Series. The American Journal of Medicine 123:3, 282-285.e2
CrossRef246
Fraser J.H. Brims, Helen E. Davies, Y.C. Gary Lee. (2010) Respiratory Chest Pain: Diagnosis and Treatment. Medical Clinics of North America 94:2, 217-232
CrossRef247
, Darren H. Freed, Dietrich Henzler, Chris W. White, Robert Fowler, Ryan Zarychanski, Jamie Hutchison, Rakesh C. Arora, Rizwan A. Manji, Jean-Francois Legare, Tanya Drews, Stasa Veroukis, Murray Kesselman, Anne-Marie Guerguerian, Anand Kumar. (2010) Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada. Canadian Journal of Anesthesia/Journal canadien d'anesthésie 57:3, 240-247
CrossRef248
A. Haktanir. (2010) MR Imaging in Novel Influenza A(H1N1)-Associated Meningoencephalitis. American Journal of Neuroradiology 31:3, 394-395
CrossRef249
Chih-Cheng Lai, Cheng-Yi Wang, Hen-I. Lin. (2010) Rhabdomyolysis and Acute Kidney Injury Associated With 2009 Pandemic Influenza A(H1N1). American Journal of Kidney Diseases 55:3, 615
CrossRef250
Edward Goldstein, Joel C. Miller, Justin J. O’Hagan, Marc Lipsitch. (2010) Pre-dispensing of antivirals to high-risk individuals in an influenza pandemic. Influenza and Other Respiratory Viruses 4:2, 101-112
CrossRef251
M. Hasegawa, K. Hashimoto, M. Morozumi, K. Ubukata, T. Takahashi, Y. Inamo. (2010) Spontaneous pneumomediastinum complicating pneumonia in children infected with the 2009 pandemic influenza A (H1N1) virus. Clinical Microbiology and Infection 16:2, 195-199
CrossRef252
Laura G. Greer, Mina Abbassi-Ghanavati, Jeanne S. Sheffield, Brian M. Casey. (2010) Diagnostic Dilemmas in a Pregnant Woman With Influenza A (H1N1) Infection. Obstetrics & Gynecology 115:Supplement, 409-412
CrossRef253
Natasha B Halasa. (2010) Update on the 2009 pandemic influenza A H1N1 in children. Current Opinion in Pediatrics 22:1, 83-87
CrossRef254
Yu-San Chien, Chia-Ping Su, Huai-Te Tsai, Angela S. Huang, Chia-En Lien, Min-Nan Hung, Jen-Hsiang Chuang, Hsu-Sung Kuo, Shan-Chwen Chang. (2010) Predictors and outcomes of respiratory failure among hospitalized pneumonia patients with 2009 H1N1 influenza in Taiwan. Journal of Infection 60:2, 168-174
CrossRef255
M. Koliou, S. Hadjiloizou, S. Ourani, A. Demosthenous, A. Hadjidemetriou. (2010) A case of benign acute childhood myositis associated with influenza A (H1N1) virus infection. Clinical Microbiology and Infection 16:2, 193-195
CrossRef256
Michel Djibré, Nadia Berkane, Anne Salengro, Edouard Ferrand, Michel Denis, Ludivine Chalumeau-Lemoine, Antoine Parrot, Charles Mayaud, Muriel Fartoukh. (2010) Non-invasive management of acute respiratory distress syndrome related to Influenza A (H1N1) virus pneumonia in a pregnant woman. Intensive Care Medicine 36:2, 373-374
CrossRef257
M. Patel, A. Dennis, C. Flutter, Z. Khan. (2010) Pandemic (H1N1) 2009 influenza. British Journal of Anaesthesia 104:2, 128-142
CrossRef258
Patrick Tang, Charles Chiu. (2010) Metagenomics for the discovery of novel human viruses. Future Microbiology 5:2, 177-189
CrossRef259
Poramate Pitak-Arnnop, Stefan Schubert, Kittipong Dhanuthai, Kraison Sappayatosok, Ute Bauer, Pichit Ngamwannagul, Uwe Gerd Liebert, Alexander Hemprich. (2010) Swine-origin H1N1 influenza A virus and dental practice: a critical review. Clinical Oral Investigations 14:1, 11-17
CrossRef260
Libster, Romina, Bugna, Jimena, Coviello, Silvina, Hijano, Diego R., Dunaiewsky, Mariana, Reynoso, Natalia, Cavalieri, Maria L., Guglielmo, Maria C., Areso, M. Soledad, Gilligan, Tomas, Santucho, Fernanda, Cabral, Graciela, Gregorio, Gabriela L., Moreno, Rina, Lutz, Maria I., Panigasi, Alicia L., Saligari, Liliana, Caballero, Mauricio T., Egües Almeida, Rodrigo M., Gutierrez Meyer, Maria E., Neder, Maria D., Davenport, Maria C., Del Valle, Maria P., Santidrian, Valeria S., Mosca, Guillermina, Garcia Domínguez, Mercedes, Alvarez, Liliana, Landa, Patricia, Pota, Ana, Boloñati, Norma, Dalamon, Ricardo, Sanchez Mercol, Victoria I., Espinoza, Marco, Peuchot, Juan Carlos, Karolinski, Ariel, Bruno, Miriam, Borsa, Ana, Ferrero, Fernando, Bonina, Angel, Ramonet, Margarita, Albano, Lidia C., Luedicke, Nora, Alterman, Elias, Savy, Vilma, Baumeister, Elsa, Chappell, James D., Edwards, Kathryn M., Melendi, Guillermina A., Polack, Fernando P., . (2010) Pediatric Hospitalizations Associated with 2009 Pandemic Influenza A (H1N1) in Argentina. New England Journal of Medicine 362:1, 45-55
Full Text261
T. Kamigaki, H. Oshitani. (2010) Influenza pandemic preparedness and severity assessment of pandemic (H1N1) 2009 in South-east Asia. Public Health 124:1, 5-9
CrossRef262
SI Bux, N Mohd. Ramli, S Ahmad Sarji, A Kamarulzaman. (2010) Chest imaging features of patients afflicted with Influenza A (H1N1) in a Malaysian tertiary referral centre. Biomedical Imaging and Intervention Journal 6:4,
CrossRef263
Marcos I. Restrepo, Marcela Mazo, Antonio Anzueto. (2010) Gripe A (H1N1). Experiencia de Estados Unidos. Archivos de Bronconeumología 46, 13-18
CrossRef264
W.R.J. Taylor, E. Burhan, H. Wertheim, P.Z. Soepandi, P. Horby, A. Fox, R. Benamore, L. de Simone, T.T. Hien, F. Chappuis. (2010) Avian influenza – A review for doctors in travel medicine. Travel Medicine and Infectious Disease 8:1, 1-12
CrossRef265
Adolfo Maximo Quispe-Laime, Jonas Daniel Bracco, Patricia Alejandra Barberio, Claudio German Campagne, Verónica Edith Rolfo, Reba Umberger, Gianfranco Umberto Meduri. (2010) H1N1 influenza A virus-associated acute lung injury: response to combination oseltamivir and prolonged corticosteroid treatment. Intensive Care Medicine 36:1, 33-41
CrossRef266
Sang In Park, Min Ji Kim, Ho Yeon Hwang, Chi Eun Oh, Jung Hyun Lee, Jae Sun Park. (2010) Clinical characteristics of children with 2009 pandemic influenza A (H1N1) admitted in a single institution. Korean Journal of Pediatrics 53:10, 886
CrossRef267
Yun Seong Kim. (2010) Respiratory Review of 2010: Pneumonia. Tuberculosis and Respiratory Diseases 68:6, 319
CrossRef268
Min Jeong Choi, Young Seok Lee, Jee Young Lee, Kun Song Lee. (2010) Novel Influenza A (H1N1) Virus Infection in Children: Chest Radiographic and CT Evaluation. Korean Journal of Radiology 11:6, 656
CrossRef269
Toshiki Yokoyama, Kenji Tsushima, Atsuhito Ushiki, Nobumitsu Kobayashi, Kazuhisa Urushihata, Tomonobu Koizumi, Keishi Kubo. (2010) Acute Lung Injury with Alveolar Hemorrhage Due to a Novel Swine-Origin Influenza A (H1N1) Virus. Internal Medicine 49:5, 427-430
CrossRef270
Alejandro Rodríguez, Thiago Lisboa, Jordi Rello. (2010) Gripe A (H1N1)v pandémica en UCI: ¿qué hemos aprendido?. Archivos de Bronconeumología 46, 24-31
CrossRef271
Kristin A. Swedish, Gina Conenello, Stephanie H. Factor. (2010) First Season of 2009 H1N1 Influenza. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 77:1, 103-113
CrossRef272
Tetsuya Nakazawa, Isao Ishikawa, Satoshi Hayama, Kyoko Morita. (2010) Respiratory failure due to novel 2009 pandemic A/H1N1 influenza in a chronic hemodialysis patient. Nihon Toseki Igakkai Zasshi 43:7, 595-600
CrossRef273
Tae Jin Yun, Gu Jin Kwon, Mi Kyeong Oh, Sung Koo Woo, Seung Hoon Park, Seung Hong Choi, Hyun Ju Lee, Jin Mo Goo, Jae-Joon Yim, Jong Sung Kim, Chang Min Park. (2010) Radiological and Clinical Characteristics of a Military Outbreak of Pandemic H1N1 2009 Influenza Virus Infection. Korean Journal of Radiology 11:4, 417
CrossRef274
Nobuaki Shime, Naoki Shimizu, Ikuya Ueta, Mami Nakayashiro, Seiichi Watanabe, Katsuki Hirai, Seiki Abe, Satoshi Nakagawa. (2010) Nihon Shuchu Chiryo Igakukai zasshi 17:1, 87-95
CrossRef275
Hagyung Lee, Yung A Kang, Hyun Su Kim, Su Yeun Shin, Jun Heung Kim, Jin Seok Kim, Sang-Bum Hong. (2010) Epidemiological Characteristics Based on the Underlying Diseases for the Deaths Related to Pandemic H1N1 Influenza in Korea. The Korean Journal of Critical Care Medicine 25:2, 83
CrossRef276
Arturo Huerta García, Nuria González Sánchez, Antoni Torres Martí. (2010) Influenza A (H1N1): manifestaciones clínicas e indicaciones profilácticas y terapéuticas. Archivos de Bronconeumología 46, 19-23
CrossRef277
Aran Lee, Yu Seun Kim, Myoung Soo Kim, Dong Jin Joo, Byung Mo Lee, Hyun Jung Kim, Soon Il Kim. (2010) Swine Influenza A (H1N1) Infection in Renal Transplant Recipients. The Journal of the Korean Society for Transplantation 24:4, 256
CrossRef278
Jae Woong Tae, Eun Jin Kim, Woo Jin Jang, Min Jeong Kim, Hae Ri Chon, Eun Soo Jeong, Young Min Koh. (2010) Two Cases of Spontaneous Pneumomediastinum Complicating Viral Pneumonia Caused by Influenza A Virus, (H1N1 Subtype) - A Case Report -. The Korean Journal of Critical Care Medicine 25:3, 163
CrossRef279
Jean Maritz, Leana Maree, Wolfgang Preiser. (2010) Pandemic influenza A (H1N1) 2009: the experience of the first six months. Clinical Chemistry and Laboratory Medicine 48:1, 11-21
CrossRef280
U. Kaisers, R. Rossaint. (2010) Neue pandemische A(H1N1)-Influenza. Der Anaesthesist 59:1, 9-10
CrossRef281
Seung Mok Ryoo, Won Young Kim, Choong Wook Lee, Chang Hwan Sohn, Dong Woo Seo, Yoon Seon Lee, Jae Ho Lee, Bum Jin Oh, Won Kim, Kyoung Soo Lim. (2010) Initial Chest CT Findings of 2009 H1N1 Influenza Pneumonia in Helping Predict Clinical Outcomes. Tuberculosis and Respiratory Diseases 69:2, 103
CrossRef282
A. Pop-Vicas, S. Gravenstein. (2010) Influenza in the Elderly – A Mini-Review. Gerontology
CrossRef283
María Luisa De Souza-Galvao, Miguel Ángel Martínez-García, Francisco Sanz, José Blanquer. (2010) Hot topics en infecciones respiratorias. Archivos de Bronconeumología 46, 8-12
CrossRef284
Kyung Ah Lim, Ye Rym Lee, Soo Yeon Cho, Du Hwan Choe, Jae Soo Koh, Byoung Jun Lee, Hye-Ryoun Kim, Cheol Hyeon Kim, Jae Cheol Lee. (2010) Diffuse Alveolar Hemorrhage Subsequently Developed after Recovery from Severe Acute Lung Injury Caused by H1N1 Influenza Infection - A Case Report -. The Korean Journal of Critical Care Medicine 25:4, 271
CrossRef285
Hee Yun Seol, Jung-Seop Eom, Mi Hyun Kim, Woo Hyun Cho, Ji Eun Kim, Ki Uk Kim, Doo Soo Jeon, Hye-Kyung Park, Yun Seong Kim, Min Ki Lee, Soon Kew Park. (2010) The First Case of Novel Influenza A (H1N1) Fatality in Korea. Tuberculosis and Respiratory Diseases 68:6, 350
CrossRef286
Shin Ahn, Won Young Kim, Ji Young Yoon, Chang Hwan Sohn, Dong Woo Seo, Sung Han Kim, Sang Bum Hong, Chae Man Lim, Youn Suck Koh, Won Kim. (2010) Procalcitonin in 2009 H1N1 Influenza Pneumonia: Role in Differentiating from Bacterial Pneumonia. Tuberculosis and Respiratory Diseases 68:4, 205
CrossRef287
Hideki Ozawa, Satomi Asai, Guilan Jin, Yuya Hasunuma, Chiharu Tanaka, Takayuki Ikeda, Moritsugu Kimura, Akihiro Ueda, Tomohiro Yamashita, Hayato Miyachi. (2010) Severe Pneumonia Caused by a Novel Influenza A (H1N1) Virus in an Asymptomatic Emphysematous Smoker. Internal Medicine 49:15, 1667-1670
CrossRef288
Cao, Bin, Li, Xing-Wang, Mao, Yu, Wang, Jian, Lu, Hong-Zhou, Chen, Yu-Sheng, Liang, Zong-An, Liang, Lirong, Zhang, Su-Juan, Zhang, Bin, Gu, Li, Lu, Lian-He, Wang, Da-Yan, Wang, Chen, . (2009) Clinical Features of the Initial Cases of 2009 Pandemic Influenza A (H1N1) Virus Infection in China. New England Journal of Medicine 361:26, 2507-2517
Full Text289
Cabot, Richard C.Harris, Nancy Lee, Shepard, Jo-Anne O., Rosenberg, Eric S., Cort, Alice M., Ebeling, Sally H.Peters, Christine C., Uyeki, Timothy M., Sharma, Amita, Branda, John A., . (2009) Case 40-2009. New England Journal of Medicine 361:26, 2558-2569
Full Text290
Clark, Tristan W., Pareek, Manish, Hoschler, Katja, Dillon, Helen, Nicholson, Karl G., Groth, Nicola, Stephenson, Iain, . (2009) Trial of 2009 Influenza A (H1N1) Monovalent MF59-Adjuvanted Vaccine. New England Journal of Medicine 361:25, 2424-2435
Full Text291
G. Rezza. (2009) Swine-origin influenza virus A(H1N1)v: lessons learnt from the early phase of the epidemic. The European Journal of Public Health 19:6, 572-573
CrossRef292
Rishi Raj, Mario Cerdan, Andresfelipe Yepeshurtado, Robert Kimbrough, Kenneth Nugent. (2009) Novel Swine-Origin (S-OIV) H1N1 Influenza A Pneumonia in a Lung Transplant Patient: A Case Report and Review of the Literature on Performance Characteristics of Rapid Screening Tests for the S-OIV. The American Journal of the Medical Sciences 338:6, 506-508
CrossRef293
Rui P. Moreno, Andrew Rhodes, Jean-Daniel Chiche. (2009) The ongoing H1N1 flu pandemic and the intensive care community: challenges, opportunities, and the duties of scientific societies and intensivists. Intensive Care Medicine 35:12, 2005-2008
CrossRef294
D. Marcelli, C. Marelli, N. Richards. (2009) Influenza A(H1N1)v pandemic in the dialysis population: first wave results from an international survey. Nephrology Dialysis Transplantation 24:12, 3566-3572
CrossRef295
Joseph Sriyal Malik Peiris, Chung Yan Cheung, Connie Yin Hung Leung, John Malcolm Nicholls. (2009) Innate immune responses to influenza A H5N1: friend or foe?. Trends in Immunology 30:12, 574-584
CrossRef296
I.W.S. Li, K.H. Chan, K.W.K. To, S.S.Y. Wong, P.L. Ho, S.K.P. Lau, P.C.Y. Woo, H.W. Tsoi, J.F.W. Chan, V.C.C. Cheng, B.J. Zheng, H. Chen, K.Y. Yuen. (2009) Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses. Journal of Clinical Virology 46:4, 325-330
CrossRef297
Santiago Echevarría-Zuno, Juan Manuel Mejía-Aranguré, Alvaro J Mar-Obeso, Concepción Grajales-Muñiz, Eduardo Robles-Pérez, Margot González-León, Manuel Carlos Ortega-Alvarez, Cesar Gonzalez-Bonilla, Ramón Alberto Rascón-Pacheco, Víctor Hugo Borja-Aburto. (2009) Infection and death from influenza A H1N1 virus in Mexico: a retrospective analysis. The Lancet 374:9707, 2072-2079
CrossRef298
Lara A. Danziger-Isakov, Shahid Husain, Martha L. Mooney, Margaret M. Hannan. (2009) The Novel 2009 H1N1 Influenza Virus Pandemic: Unique Considerations for Programs in Cardiothoracic Transplantation. The Journal of Heart and Lung Transplantation 28:12, 1341-1347
CrossRef299
V Alberto Laguna-Torres, Jorge Gomez Benavides. (2009) Infection and death from influenza A H1N1 virus in Mexico. The Lancet 374:9707, 2032-2033
CrossRef300
S. H. Ebrahim, Z. A. Memish, T. M. Uyeki, T. A. M. Khoja, N. Marano, S. J. N. McNabb. (2009) Pandemic H1N1 and the 2009 Hajj. Science 326:5955, 938-940
CrossRef301
Wenzel, Richard P., Edmond, Michael B., . (2009) Preparing for 2009 H1N1 Influenza. New England Journal of Medicine 361:20, 1991-1993
Full Text302
Carlos Del Rio, Carlos Franco-Paredes. (2009) The Perennial Threat of Influenza Pandemics. Archives of Medical Research 40:8, 641-642
CrossRef303
Jeannette Guarner, Reynaldo Falcón-Escobedo. (2009) Comparison of the Pathology Caused by H1N1, H5N1, and H3N2 Influenza Viruses. Archives of Medical Research 40:8, 655-661
CrossRef304
Mauricio Rodríguez-Álvarez, Ana María Velasco-Velasco, Nelson J. Álvarez-Anell, María Eugenia Jiménez-Corona, Samuel Ponce de León-Rosales. (2009) Identification of Seasonal Vaccine Hemagglutinin Subtype 1 (H1) Epitopes in Mexican Isolates of the New Influenza A (H1N1) 2009 Virus. Archives of Medical Research 40:8, 687-692
CrossRef305
Carlos Del Rio, Mauricio Hernandez-Avila. (2009) Lessons from Previous Influenza Pandemics and from the Mexican Response to the Current Influenza Pandemic. Archives of Medical Research 40:8, 677-680
CrossRef306
Israel Grijalva-Otero, Juan Osvaldo Talavera, Fortino Solorzano-Santos, Guillermo Vazquez-Rosales, Svetlana Vladislavovna-Doubova, Ricardo Pérez-Cuevas, Guadalupe Miranda-Novales, Carmen García-Peña, Claudia Espinel-Bermúdez, Javier Torres, Jorge Escobedo de la Peña. (2009) Critical Analysis of Deaths Due to Atypical Pneumonia during the Onset of the Influenza A (H1N1) Virus Epidemic. Archives of Medical Research 40:8, 662-668
CrossRef307
M. Patel, A. Dennis, C. Flutter, S. Thornton, O. D’Mello, N. Sherwood. (2009) Pandemic (H1N1) 2009 influenza: experience from the critical care unit. Anaesthesia 64:11, 1241-1245
CrossRef308
Vincent C.C. Cheng, Yuk-Kong Lau, Kwok-Lun Lee, Kwan-Ho Yiu, Kwok-Hung Chan, Pak-Leung Ho, Kwok-Yung Yuen. (2009) Fatal co-infection with swine origin influenza virus A/H1N1 and community-acquired methicillin-resistant Staphylococcus aureus. Journal of Infection 59:5, 366-370
CrossRef309
J. S. Malik Peiris, Wen-wei Tu, Hui-ling Yen. (2009) A novel H1N1 virus causes the first pandemic of the 21 st century. European Journal of Immunology 39:11, 2946-2954
CrossRef310
M. Michaelis, H. W. Doerr, J. Cinatl. (2009) An influenza A H1N1 virus revival – pandemic H1N1/09 virus. Infection 37:5, 381-389
CrossRef311
Josep Vaqué Rafart, Julita Gil Cuesta, María Brotons Agulló. (2009) Principales características de la pandemia por el nuevo virus influenza A (H1N1). Medicina Clínica 133:13, 513-521
CrossRef312
F. Trémolières. (2009) Les antiviraux de la grippe servent-ils à quelque chose ?. Médecine et Maladies Infectieuses 39:9, 667-673
CrossRef313
Paula Lister, Fiona Reynolds, Roger Parslow, Alex Chan, Mehrengise Cooper, Adrian Plunkett, Shelly Riphagen, Mark Peters. (2009) Swine-origin influenza virus H1N1, seasonal influenza virus, and critical illness in children. The Lancet 374:9690, 605-607
CrossRef314
Kyong-Hak Lee, Kilsoo Yie, Won Sup Oh, Sook-Won Ryu, Sung-Bin Chon, Seung-Joon Lee. (2009) Early Extracorporeal Membrane Oxygenation in a Patient with Pandemic Influenza (H1N1 2009) and Acute Respiratory Distress Syndrome. Infection and Chemotherapy 42:2, 122
CrossRef315
Hitoshi OSHITANI. (2009) Influenza Pandemic (H1N1) 2009. Uirusu 59:2, 139-144
CrossRef316
Choong Wook Lee, Joon Beom Seo, Jae-Woo Song, Hyun Joo Lee, Jin Seong Lee, Mi Young Kim, Eun Jin Chae, Jin Woo Song, Won Young Kim. (2009) Pulmonary Complication of Novel Influenza A (H1N1) Infection: Imaging Features in Two Patients. Korean Journal of Radiology 10:6, 531
CrossRef317
Ki Hwan Kim, Hye Jin Park, Dong Soo Kim. (2009) Clinical Characteristic of Respiratory Tract Infections in Children during Pandemic Influenza (H1N1 2009) in Korea. Infection and Chemotherapy 42:2, 76
CrossRef318
Jung Hyun Kim, Soon Hyo Kwon, Eun Jung Lee, Eun Jung Kim, Tae Hyong Kim, Jin Seok Jeon, Hyunjin Noh, Dong Cheol Han. (2009) Two Cases of Respiratory Distress Syndrome Caused by Hospital-Acquired Pandemic Influenza (H1N1 2009) in Kidney Transplant Recipients. Infection and Chemotherapy 42:2, 117
CrossRef319
Manish Sinha. (2009) Swine flu. Journal of Infection and Public Health 2:4, 157-166
CrossRef320
Sung-Han Kim. (2009) Treatment of Severe Pandemic Influenza A/H1N1 Infection. Infection and Chemotherapy 41:5, 265
CrossRef321
Jong Hoo Lee, Miok Kim, Jaechun Lee, Jinseok Kim, Sang Yop Shin. (2009) A Case of Acute Pulmonary Thromboembolism Complicated Pandemic Influenza (H1N1 2009). Infection and Chemotherapy 42:2, 127
CrossRef
