Original Article
Adiposity as Compared with Physical Activity in Predicting Mortality among Women
N Engl J Med 2004; 351:2694-2703December 23, 2004
- Abstract
Background
Whether higher levels of physical activity can counteract the elevated risk of death associated with adiposity is controversial.
Methods
We examined the associations of the body-mass index and physical activity with death among 116,564 women who, in 1976, were 30 to 55 years of age and free of known cardiovascular disease and cancer.
Results
During 24 years of follow-up, 10,282 deaths occurred — 2370 from cardiovascular disease, 5223 from cancer, and 2689 from other causes. Mortality rates increased monotonically with higher body-mass-index values among women who had never smoked (P for trend <0.001). In combined analyses of all participants, adiposity predicted a higher risk of death regardless of the level of physical activity. Higher levels of physical activity appeared to be beneficial at all levels of adiposity but did not eliminate the higher risk of death associated with obesity. As compared with women who were lean (i.e., they had a body-mass index lower than 25) and active (they spent 3.5 or more hours exercising per week), the multivariate relative risks of death were 1.55 (95 percent confidence interval, 1.42 to 1.70) for lean and inactive women, 1.91 (95 percent confidence interval, 1.60 to 2.30) for women who were obese (defined as a body-mass index of 30 or higher) but active, and 2.42 (95 percent confidence interval, 2.14 to 2.73) for inactive, obese women. Even modest weight gain during adulthood, independent of physical activity, was associated with a higher risk of death. We estimate that excess weight (defined as a body-mass index of 25 or higher) and physical inactivity (less than 3.5 hours of exercise per week) together could account for 31 percent of all premature deaths, 59 percent of deaths from cardiovascular disease, and 21 percent of deaths from cancer among nonsmoking women.
Conclusions
Both increased adiposity and reduced physical activity are strong and independent predictors of death.
Media in This Article
Figure 1
Multivariate Relative Risks of Death from Cardiovascular Disease (Panel A), Cancer (Panel B), and Other Causes (Panel C) According to Body-Mass Index among Women Who Had Never Smoked.Table 1
Body-Mass Index and Relative Risk of Death from All Causes during 24 Years of Follow-up.Article Activity
- Article
Obesity and physical inactivity are major public health problems in the United States. Approximately two thirds of Americans are classified as overweight or obese (defined as having a body-mass index [the weight in kilograms divided by the square of the height in meters] of 25 or higher),1 and the vast majority do not engage in regular physical activity.2 Persuasive evidence indicates that both obesity and physical inactivity are risk factors for the development of major chronic diseases and premature death.3 However, the optimal weight and levels of physical activity for longevity continue to be debated, and few epidemiologic studies have examined adiposity and physical activity simultaneously in relation to mortality. It has been suggested that higher levels of physical fitness can eliminate the effect of excess weight and obesity on morbidity and mortality and that, thus, obesity may be a less important determinant of mortality than is fitness. However, evidence in support of this hypothesis has been limited and inconsistent.4,5 We therefore extended our previous analyses of body-mass index and mortality in the Nurses' Health Study6 to 24 years of follow-up to address the long-term relationship between body-mass index and mortality and to examine whether higher levels of physical activity attenuate the association between the body-mass index and mortality.
Methods
The cohort of the Nurses' Health Study was established in 1976, when 121,700 female registered nurses who were 30 to 55 years old completed a mailed questionnaire about their medical history and lifestyle. Women in the study have provided current information regarding lifestyle and health conditions every two years since 1976. After excluding women with reported cardiovascular disease and cancer in the baseline questionnaire, we included 116,564 women in the analysis of obesity and mortality. The 1980 questionnaire asked about weight at 18 years of age; about 80 percent of the participants provided the information. Beginning in 1980, diet was assessed with the use of validated semiquantitative questionnaires about the frequency with which certain foods were eaten.7 The study was approved by the Human Research Committee at the Brigham and Women's Hospital in Boston; completion of the self-administered questionnaire was considered to imply informed consent.
Overall and Abdominal Adiposity
As a measure of overall obesity, we calculated the body-mass index. Self-reported weight was validated among 184 participants in the Nurses' Health Study who were living in the Boston area; self-reported weight was highly correlated with measured weight (r=0.96; mean difference [self-reported weight minus measured weight], –1.5 kg).8 Weight as recalled at 18 years of age was also highly correlated with measured weight (r=0.87; mean difference [recalled weight minus measured weight], –1.4 kg) in the physical-examination records for the same age among 118 women from another cohort of female nurses.9 In 1986, participants in the Nurses' Health Study reported direct measurements of their waists (at the umbilicus) and hips (at the largest circumference) to the nearest quarter of an inch.10
Physical Activity
In 1980 and 1982, women were asked to report the average number of hours they had spent each week during the previous year engaging in moderate physical activity (e.g., brisk walking) and in vigorous activity (e.g., strenuous sports and jogging). In 1986, women were asked to complete an eight-item questionnaire regarding the average time they spent per week walking, jogging, running, bicycling, swimming laps, playing tennis or squash, and participating in calisthenics. Similar data were collected in 1988, 1992, 1996, and 1998, which allowed us to calculate the average amount of time per week that was spent in moderate to vigorous activity (i.e., those, including brisk walking, that required 3.5 or more metabolic equivalents [MET] per hour) at each time point.11 Our validation study indicated relatively good validity and reproducibility for the questionnaire.12 The correlation between physical activity as reported in one-week recalls and that reported on the questionnaires was 0.79. The correlation between moderate-to-vigorous activity as reported in diaries and that reported on the questionnaires was 0.62. In a separate population of 103 women who were 20 to 59 years old, the correlation between the physical-activity score, as determined on a very similar questionnaire, and maximal oxygen consumption was 0.54.13 In our previous analyses, the level of physical activity was a strong predictor of morbidity and mortality.11,14-16
End Points
Deaths were reported by the next of kin or the postal authorities or were ascertained through the National Death Index. We estimate that follow-up for deaths was more than 98 percent complete.17 For all deaths, we sought death certificates and, when appropriate, requested permission from the next of kin to review medical records. The underlying cause of death was assigned according to the International Classification of Diseases, 8th Revision (ICD-8). The primary end point in this analysis was death from any cause. We also conducted analyses according to the causes of death, which were divided into cancer (ICD-8 codes 140.0 through 207.9), cardiovascular disease (ICD-8 codes 390.0 through 458.9 and 795.0 to 795.9), and all other causes.
Statistical Analysis
In order to reduce the effects of underlying disease on weight, we used the baseline body-mass index in our analyses. We grouped women into nine categories according to the body-mass index as measured in 1976. We calculated the change between the weight at the age of 18 years and that in 1980 and grouped women into five categories. For all analyses, we excluded women who had reported cancer or cardiovascular disease at baseline. Person-years were calculated from the date of return of the 1976 questionnaire (for analyses of body-mass index) or the 1980 questionnaire (for analyses of physical activity) until the date of death or June 1, 2000, whichever came first. The relative risk of death was calculated as the rate of death among women within a given body-mass-index category as compared with that in the reference category. Age-adjusted analyses were conducted with the use of five-year age categories and the Mantel–Haenszel test.18 The Cox proportional-hazards model19 was used to adjust for age or other potential confounding variables, including smoking status, alcohol use, menopausal status and use or nonuse of hormone-replacement therapy, and presence or absence of a parental history of myocardial infarction before 60 years of age.
In our examination of the combined effects of physical activity and body-mass index on mortality, we used 1980 as the baseline. To represent long-term levels of physical activity most accurately and to reduce measurement error, we calculated the cumulative average number of hours of moderate-to-vigorous activity from all available questionnaires up to the start of each two-year follow-up interval.15 In the secondary analysis, we controlled for the ratio of polyunsaturated to saturated fat consumed and for the intake of trans fat and fiber (all in quintiles). Likelihood-ratio tests were used to examine interactions between physical activity and obesity in relation to mortality with the comparison of nested models with and without the interaction variables of activity and obesity.
We calculated the population attributable risk conferred by excess weight (defined as a body-mass index of 25 or higher) and physical inactivity (defined as less than 3.5 hours per week of moderate-to-vigorous activity) to estimate the percentage of premature deaths in our cohort that, theoretically, would not have occurred if all women had been in the low-risk group (i.e, they were not overweight and engaged in regular exercise), assuming a causal relationship between the risk factors and mortality.20 Statistical analyses were conducted with the use of SAS software, version 8.2. All reported P values are based on two-sided tests.
Results
During 24 years of follow-up (approximately 2.7 million person-years), we identified 10,282 deaths — 2370 from cardiovascular disease, 5223 from cancer, and 2689 from other causes. We observed a J-shaped relationship between body-mass index and overall mortality in age-adjusted analyses (Table 1Table 1
Body-Mass Index and Relative Risk of Death from All Causes during 24 Years of Follow-up.). However, when we restricted the analyses to women who had never smoked, in order to minimize confounding by this major cause of death,21 we observed a direct monotonic relationship between the body-mass index and mortality. The lowest mortality was among women with a body-mass index of less than 23. There was a slight J-shaped relationship between body-mass index and mortality among former smokers, but the relationship was more evident among current smokers. Further adjustment for the number of cigarettes smoked per day and the duration of the period of smoking did not appreciably alter the relationship. Figure 1Figure 1Multivariate Relative Risks of Death from Cardiovascular Disease (Panel A), Cancer (Panel B), and Other Causes (Panel C) According to Body-Mass Index among Women Who Had Never Smoked. shows multivariate relative risks of death from specific causes among women who had never smoked. The monotonic relationship held for deaths from cancer and, more strongly, for deaths from cardiovascular causes. For other deaths, the increased risk in the leanest group was primarily due to chronic obstructive pulmonary disease and cirrhosis.In multivariate analyses, both excess weight or obesity and physical inactivity were significantly associated with increased mortality (Table 2Table 2
Multivariate Relative Risks of Death from Any Cause and Death from Specific Causes According to Body-Mass Index and Physical Activity.). In the group of women who had never smoked, overall mortality was twice as high among those who were obese (body-mass index, 30 or higher) as among those who were lean (body-mass index, less than 25). Mortality from cardiovascular disease was three times as high, and mortality from cancer was increased by 65 percent. Physical inactivity (less than one hour per week of exercise) was associated with a 52 percent increase in overall mortality, a doubling of mortality from cardiovascular disease, and a 29 percent increase in mortality from cancer. Adjustment for the body-mass index slightly attenuated these relative risks, but smoking status did not confound the associations.We next examined the combined effects of body-mass index and physical activity on mortality (Table 3Table 3
Multivariate Relative Risks of Death from Any Cause and Death from Specific Causes According to Joint Categories of Body-Mass Index and Physical Activity.). Excess weight and obesity predicted an increase in mortality regardless of the physical-activity level, and there was no evidence that higher levels of physical activity attenuated the association between obesity and mortality. As compared with women who were lean (i.e., who had a body-mass index lower than 25) and active (they spent 3.5 or more hours exercising per week), the multivariate relative risks of death were 1.55 (95 percent confidence interval, 1.42 to 1.70) for lean and inactive women, 1.91 (95 percent confidence interval, 1.60 to 2.30) for women who were obese (body-mass index, 30 or higher) but active, and 2.42 (95 percent confidence interval, 2.14 to 2.73) for inactive, obese women.The association between physical activity and mortality was somewhat stronger among lean women than among overweight women, but the test for an interaction was not statistically significant (P=0.06 for overall mortality, P=0.37 for mortality from cardiovascular disease, and P=0.22 for mortality from cancer). Further adjustment for dietary factors (the ratio of polyunsaturated to saturated fat and the amount of trans fat and fiber) did not appreciably change the results. The designation of a higher level of physical activity (seven or more hours per week) as the cutoff point did not alter the overall findings.
In a secondary analysis for which 1986 was the baseline period, abdominal obesity (defined according to the waist-to-hip ratio) predicted increases in overall and cause-specific mortality that were independent of physical-activity levels. Women with the highest waist-to-hip ratios and the lowest levels of physical activity had the highest mortality (relative risk of death, as compared with women who had the lowest waist-to-hip ratio and the highest levels of physical activity, 2.84; 95 percent confidence interval, 2.25 to 3.57). Both the waist-to-hip ratio and the circumference of the waist were significant predictors of mortality after adjustments were made for body-mass index, physical activity, and other covariates (multivariate relative risks, from the lowest to the highest quintile, 1.00, 1.19, 1.40, 1.59, and 2.20 for waist circumference and 1.00, 1.14, 1.25, 1.51, and 1.84 for the waist-to-hip ratio; P<0.001 for both variables).
Table 4Table 4
Weight Change and Relative Risk of Death According to Level of Physical Activity among Women Who Had Never Smoked. shows the association between a change in weight during adulthood (from the age of 18 years until 1980) and overall mortality and cause-specific mortality (from 1980 through 2000), according to the level of physical activity as assessed in 1980. Even a modest weight gain (4 to 10 kg) was significantly associated with an increase in mortality (relative risk of death, 1.15; 95 percent confidence interval, 1.01 to 1.31). The increased mortality associated with weight gain was not mitigated by higher levels of physical activity. Weight loss was associated with an increase in mortality from cardiovascular disease among sedentary women.In our cohort, the prevalence of either excess weight (a body-mass index of 25 or higher) or physical inactivity (less than 3.5 hours per week) was 80.7 percent among all participants and 81.6 percent among women who had never smoked as of 1992. We estimate that excess weight and physical inactivity together accounted for 26 percent of all premature deaths, 47 percent of deaths from cardiovascular disease, and 16 percent of deaths from cancer in the overall cohort, and for 31 percent of all deaths, 59 percent of deaths from cardiovascular disease, and 21 percent of deaths from cancer among women who had never smoked.
Discussion
In this large cohort study of middle-aged women, the body-mass index and level of physical activity significantly and independently predicted mortality. A high level of physical activity did not eliminate excess mortality associated with obesity. Also, leanness did not counteract the increase in mortality conferred by inactivity. The lowest mortality was among physically active, lean women. Weight gain during adulthood was also a strong and independent risk factor for premature death, regardless of the level of physical activity.
Although obesity is clearly associated with an increase in mortality, the health consequences of being mildly to moderately overweight have been less clear. Many epidemiologic studies have suggested that leanness may be associated with an increase in mortality.3 However, there is little evidence that leanness is associated with a higher incidence of major chronic disease. To the contrary, even a body-mass index in the upper part of the normal range increases the risk of diabetes, hypertension, and coronary heart disease.22 Although overall mortality is a simple and useful end point, epidemiologic studies of body weight and mortality are prone to methodologic biases that result from reverse causation (i.e., a low body-mass index is sometimes the result, rather than the cause, of underlying illness) and from confounding by smoking. These artifacts can lead to the J-shaped or U-shaped relationship between body-mass index and mortality and to a systematic underestimation of the effect of obesity on mortality.21 In the present analyses, the linear relationship between body-mass index and mortality emerged only when the analyses were restricted to women who had never smoked. Our results are consistent with those of the Cancer Prevention Study II,23 in which the relationship between body-mass index and mortality was substantially modified by smoking; among participants in that study who had never smoked, the mortality was lowest among women with a body-mass index of 22.0 to 23.4.
There is convincing evidence that increased levels of physical activity help reduce the risk of premature death.3 Cardiorespiratory fitness, as measured by a treadmill-exercise test, is also a powerful predictor of mortality.24 It has been hypothesized that physical fitness may eliminate the adverse effects of obesity on mortality. In an eight-year follow-up of 21,925 men 30 to 83 years of age in the Aerobics Center Longitudinal Study (in which 428 deaths occurred), Lee et al.4 reported that physical fitness completely abrogated the excess mortality associated with increased body fat. However, in the Lipid Research Clinics Study,5 both physical fitness and adiposity predicted overall mortality and mortality from cardiovascular disease, and physical fitness did not negate the association between obesity and excess mortality. Wessel et al.25 recently reported that among 906 women who underwent coronary angiography for suspected ischemia, a higher level of self-reported physical fitness, but not a lower body-mass index, was significantly associated with a lower incidence of cardiovascular events. However, these results may be affected by residual confounding due to reverse causation, because existing coronary heart disease could lead to weight loss and could also limit exercise.
In the present study, we did not assess cardiorespiratory fitness. However, physical activity is the primary determinant of fitness that can be modified, and even moderate levels of physical activity (e.g., 30 minutes per day of brisk walking) can bring about levels of cardiorespiratory fitness that have been associated with a significant reduction in mortality.26 In our study, the adverse effects of excess weight on mortality were persistent in both lower and higher physical-activity categories. Thus, our data do not support the hypothesis that a higher level of physical activity eliminates the excess mortality associated with increased body fat. Some unusually muscular persons with a body-mass index over 30 who are active and fit may have a relatively low risk of death, but such persons must be rare: only 2 percent of women in our study were both physically active and obese, and the overall risk of death in this group was twice that among lean and active women.
Measurement errors in self-reported levels of physical activity might have biased the association between physical activity and mortality toward the null hypothesis. In addition, obese participants might have exaggerated their physical-activity levels. However, our previous analyses demonstrated that the level of physical activity predicted the risk of diabetes27 and coronary heart disease14 in both lean and obese subjects. Because physical activity was assessed periodically during the follow-up period, our analyses with the use of the repeated measurements not only reduced errors in measurement but also took into account real changes in levels of physical activity over time.
Although our data are from women, they are broadly consistent with findings in two cohort studies of men,28,29 which showed that the excess mortality associated with obesity was similar among physically active and sedentary men. In the Health Professionals Follow-Up Study,29 the risk of death among lean and active men was not increased, but among the leanest men who were also sedentary, the risk of death was increased by a factor of two.
Because our study population is primarily white and is made up of registered nurses, the relative homogeneity of the cohort with respect to socioeconomic status and educational level reduces confounding and enhances the internal validity of the study. On the other hand, our results may not apply to other racial or ethnic groups. Previous studies of black and Hispanic populations have been limited but have generally found that broad ranges of the body-mass index are associated with the lowest mortality.30 Whether physical activity or fitness modifies the relationship between body-mass index and mortality in these populations remains to be studied.
In conclusion, we found that both the body-mass index and the level of physical activity were important and independent predictors of mortality and that a higher level of physical activity does not appear to negate the risk associated with adiposity. Women who were both lean and physically active had the lowest mortality. Also, our data on women who were followed for 24 years continue to show a monotonic relationship between the body-mass index and mortality among those who have never smoked, with the lowest mortality among women with a body-mass index of less than 23. Furthermore, even a moderate weight gain during adulthood was associated with an increase in mortality that was independent of the physical-activity level. Thus, public health campaigns should emphasize both the maintenance of a healthy weight and regular physical activity.
Supported by grants (HL24074, HL34594, P30 DK46200, and CA87969) from the National Institutes of Health. Dr. Hu is the recipient of an American Heart Association Established Investigator Award.
Source Information
From the Departments of Nutrition (F.B.H., W.C.W., T.L., M.J.S.) and Epidemiology (F.B.H., W.C.W., M.J.S., G.A.C., J.E.M.), Harvard School of Public Health; and the Channing Laboratory (F.B.H., W.C.W., M.J.S., G.A.C., J.E.M.) and the Division of Preventive Medicine (J.E.M.), Department of Medicine, Harvard Medical School and Brigham and Women's Hospital — all in Boston.
Address reprint requests to Dr. Hu at the Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave., Boston, MA 02115, or at frank.hu@channing.harvard.edu.
- References
References
1
Flegal KM ,Carroll MD ,Ogden CL ,Johnson CL . Prevalence and trends in obesity among US adults, 1999-2000. JAMA 2002;288:1723-1727
CrossRef | Web of Science | Medline2
Simpson ME ,Serdula M ,Galuska DA , et al. Walking trends among U.S. adults: the Behavioral Risk Factor Surveillance System, 1987-2000. Am J Prev Med 2003;25:95-100
CrossRef | Web of Science | Medline3
Katzmarzyk PT ,Janssen I ,Ardern CI . Physical inactivity, excess adiposity and premature mortality. Obes Rev 2003;4:257-290
CrossRef | Medline4
Lee CD ,Blair SN ,Jackson AS . Cardiorespiratory fitness, body composition, and all-cause and cardiovascular disease mortality in men. Am J Clin Nutr 1999;69:373-380
Web of Science | Medline5
Stevens J ,Cai J ,Evenson KR ,Thomas R . Fitness and fatness as predictors of mortality from all causes and from cardiovascular disease in men and women in the Lipid Research Clinics Study. Am J Epidemiol 2002;156:832-841
CrossRef | Web of Science | Medline6
Manson JE ,Willett WC ,Stampfer MJ , et al. Body weight and mortality among women. N Engl J Med 1995;333:677-685
Full Text | Web of Science | Medline7
Willett WC ,Sampson L ,Stampfer MJ , et al. Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol 1985;122:51-65
Web of Science | Medline8
Willett W ,Stampfer MJ ,Bain C , et al. Cigarette smoking, relative weight, and menopause. Am J Epidemiol 1983;117:651-658
Web of Science | Medline9
Troy LM ,Hunter DJ ,Manson JE ,Colditz GA ,Stampfer MJ ,Willett WC . The validity of recalled weight among younger women. Int J Obes Relat Metab Disord 1995;19:570-572
Web of Science | Medline10
Rimm EB ,Stampfer MJ ,Colditz GA ,Chute CG ,Litin LB ,Willett WC . Validity of self-reported waist and hip circumferences in men and women. Epidemiology 1990;1:466-473
CrossRef | Medline11
Rockhill B ,Willett WC ,Manson JE , et al. Physical activity and mortality: a prospective study among women. Am J Public Health 2001;91:578-583
CrossRef | Web of Science | Medline12
Wolf AM ,Hunter DJ ,Colditz GA , et al. Reproducibility and validity of a self-administered physical activity questionnaire. Int J Epidemiol 1994;23:991-999
CrossRef | Web of Science | Medline13
Jacobs DR Jr ,Ainsworth BE ,Hartman TJ ,Leon AS . A simultaneous evaluation of 10 commonly used physical activity questionnaires. Med Sci Sports Exerc 1993;25:81-91
CrossRef | Web of Science | Medline14
Manson JE ,Hu FB ,Rich-Edwards JW , et al. A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in women. N Engl J Med 1999;341:650-658
Full Text | Web of Science | Medline15
Hu FB ,Stampfer MJ ,Colditz GA , et al. Physical activity and risk of stroke in women. JAMA 2000;283:2961-2967
CrossRef | Web of Science | Medline16
Hu FB ,Manson JE ,Stampfer MJ , et al. Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med 2001;345:790-797
Full Text | Web of Science | Medline17
Stampfer MJ ,Willett WC ,Speizer FE , et al. Test of the National Death Index. Am J Epidemiol 1984;119:837-839
Web of Science | Medline18
Mantel N . Chi-square tests with one degree of freedom: extensions of the Mantel-Haenszel procedure. J Am Stat Assoc 1963;58:690-700
CrossRef | Web of Science19
Cox DR, Oakes D. Analysis of survival data. London: Chapman and Hall, 1987.
20
Rothman KJ, Greenland S. Modern epidemiology. 2nd ed. Philadelphia: Lippincott-Raven, 1998.
21
Manson JE ,Stampfer MJ ,Hennekens CH ,Willett WC . Body weight and longevity: a reassessment. JAMA 1987;257:353-358
CrossRef | Web of Science | Medline22
Willett WC ,Dietz WH ,Colditz GA . Guidelines for healthy weight. N Engl J Med 1999;341:427-434
Full Text | Web of Science | Medline23
Calle EE ,Thun MJ ,Petrelli JM ,Rodriguez C ,Heath CW Jr . Body-mass index and mortality in a prospective cohort of U.S. adults. N Engl J Med 1999;341:1097-1105
Full Text | Web of Science | Medline24
Blair SN ,Cheng Y ,Holder JS . Is physical activity or physical fitness more important in defining health benefits? Med Sci Sports Exerc 2001;33:Suppl:S379-S399
CrossRef | Web of Science | Medline25
Wessel TR ,Arant CB ,Olson MB , et al. Relationship of physical fitness vs body mass index with coronary artery disease and cardiovascular events in women. JAMA 2004;292:1179-1187
CrossRef | Web of Science | Medline26
Stofan JR ,DiPietro L ,Davis D ,Kohl HW III ,Blair SN . Physical activity patterns associated with cardiorespiratory fitness and reduced mortality: the Aerobics Center Longitudinal Study. Am J Public Health 1998;88:1807-1813
CrossRef | Web of Science | Medline27
Hu FB ,Sigal RJ ,Rich-Edwards JW , et al. Walking compared with vigorous physical activity and risk of type 2 diabetes in women: a prospective study. JAMA 1999;282:1433-1439
CrossRef | Web of Science | Medline28
Ajani UA ,Lotufo PA ,Gaziano JM , et al. Body mass index and mortality among US male physicians. Ann Epidemiol 2004;14:731-739
CrossRef | Web of Science | Medline29
Baik I ,Ascherio A ,Rimm EB , et al. Adiposity and mortality in men. Am J Epidemiol 2000;152:264-271
CrossRef | Web of Science | Medline30
Stevens J . Obesity and mortality in African-Americans. Nutr Rev 2000;58:346-353
CrossRef | Web of Science | Medline
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CrossRef15
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CrossRef16
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CrossRef17
Andrew Currie, Andrew Chetwood, Ahmed R. Ahmed. (2011) Bariatric Surgery and Renal Function. Obesity Surgery 21:4, 528-539
CrossRef18
2011. References. , 283-360.
CrossRef19
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CrossRef20
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CrossRef21
F. K. Assah, U. Ekelund, S. Brage, A. Wright, J. C. Mbanya, N. J. Wareham. (2011) Accuracy and validity of a combined heart rate and motion sensor for the measurement of free-living physical activity energy expenditure in adults in Cameroon. International Journal of Epidemiology 40:1, 112-120
CrossRef22
Noel D. Aldrich, Marla M. Reicks, Shalamar D. Sibley, J. Bruce Redmon, William Thomas, Susan K. Raatz. (2011) Varying protein source and quantity do not significantly improve weight loss, fat loss, or satiety in reduced energy diets among midlife adults. Nutrition Research 31:2, 104-112
CrossRef23
J. S. Rana, B. J. Arsenault, J.-P. Despres, M. Cote, P. J. Talmud, E. Ninio, J. Wouter Jukema, N. J. Wareham, J. J. P. Kastelein, K.-T. Khaw, S. Matthijs Boekholdt. (2011) Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women. European Heart Journal 32:3, 336-344
CrossRef24
H. J. Baer, R. J. Glynn, F. B. Hu, S. E. Hankinson, W. C. Willett, G. A. Colditz, M. Stampfer, B. Rosner. (2011) Risk Factors for Mortality in the Nurses' Health Study: A Competing Risks Analysis. American Journal of Epidemiology 173:3, 319-329
CrossRef25
Benjamin Longo-Mbenza, Huguette Nkongo Mvindu, Jean Bosco Kasiam On’kin, Nkakudulu Bikuku, Bernard Kianu Phanzu, Augustin Nge Okwe, Nelly Kabangu. (2011) The deleterious effects of physical inactivity on elements of insulin resistance and metabolic syndrome in Central Africans at high cardiovascular risk. Diabetes and Metabolic Syndrome: Clinical Research and Reviews 5:1, 1-6
CrossRef26
Riccardo Dalle Grave, Simona Calugi, Elena Centis, Marwan El Ghoch, Giulio Marchesini. (2011) Cognitive-Behavioral Strategies to Increase the Adherence to Exercise in the Management of Obesity. Journal of Obesity 2011, 1-11
CrossRef27
Kanae Furuya, Tomoko Kimura, Michitaka Naito. (2011) The Relation Between Body Mass Index and Subjective Health in Female Students. The Japanese Journal of Nutrition and Dietetics 69:6, 326-334
CrossRef28
Edwin S Wong, Bruce CM Wang, Louis P Garrison, Rafael Alfonso-Cristancho, David R Flum, David E Arterburn, Sean D Sullivan. (2011) Examining the BMI-mortality relationship using fractional polynomials. BMC Medical Research Methodology 11:1, 175
CrossRef29
Berrington de Gonzalez, Amy, Hartge, Patricia, Cerhan, James R., Flint, Alan J., Hannan, Lindsay, MacInnis, Robert J., Moore, Steven C., Tobias, Geoffrey S., Anton-Culver, Hoda, Freeman, Laura Beane, Beeson, W. Lawrence, Clipp, Sandra L., English, Dallas R., Folsom, Aaron R., Freedman, D. Michal, Giles, Graham, Hakansson, Niclas, Henderson, Katherine D., Hoffman-Bolton, JudithHoppin, Jane A., Koenig, Karen L., Lee, I-Min, Linet, Martha S., Park, Yikyung, Pocobelli, Gaia, Schatzkin, Arthur, Sesso, Howard D., Weiderpass, Elisabete, Willcox, Bradley J., Wolk, Alicja, Zeleniuch-Jacquotte, Anne, Willett, Walter C., Thun, Michael J., . (2010) Body-Mass Index and Mortality among 1.46 Million White Adults. New England Journal of Medicine 363:23, 2211-2219
Full Text30
Gang Chen, Chune Liu, Jin Yao, Qiqin Jiang, Nianhui Chen, Huibin Huang, Jixing Liang, Liantao Li, Lixiang Lin. (2010) Overweight, obesity, and their associations with insulin resistance and β-cell function among Chinese: a cross-sectional study in China. Metabolism 59:12, 1823-1832
CrossRef31
STEPHEN W. FARRELL, SHANNON J. FITZGERALD, PAUL A. McAULEY, CAROLYN E. BARLOW. (2010) Cardiorespiratory Fitness, Adiposity, and All-Cause Mortality in Women. Medicine & Science in Sports & Exercise 42:11, 2006-2012
CrossRef32
Rino Bellocco, Chongqi Jia, Weimin Ye, Ylva Trolle Lagerros. (2010) Effects of physical activity, body mass index, waist-to-hip ratio and waist circumference on total mortality risk in the Swedish National March Cohort. European Journal of Epidemiology 25:11, 777-788
CrossRef33
Benjamin M. Meador, Kimberly A. Huey. (2010) Statin-associated myopathy and its exacerbation with exercise. Muscle & Nerve 42:4, 469-479
CrossRef34
Doreen Kuhlow, Kim Zarse, Anja Voigt, Tim J. Schulz, Klaus J. Petzke, Lutz Schomburg, Andreas F. H. Pfeiffer, Michael Ristow. (2010) Opposing effects of dietary sugar and saturated fat on cardiovascular risk factors and glucose metabolism in mitochondrially impaired mice. European Journal of Nutrition 49:7, 417-427
CrossRef35
J. Pucher, R. Buehler, D. R. Bassett, A. L. Dannenberg. (2010) Walking and Cycling to Health: A Comparative Analysis of City, State, and International Data. American Journal of Public Health 100:10, 1986-1992
CrossRef36
A. V. Patel, L. Bernstein, A. Deka, H. S. Feigelson, P. T. Campbell, S. M. Gapstur, G. A. Colditz, M. J. Thun. (2010) Leisure Time Spent Sitting in Relation to Total Mortality in a Prospective Cohort of US Adults. American Journal of Epidemiology 172:4, 419-429
CrossRef37
Marion L. Vetter, Lucy F. Faulconbridge, Victoria L. Webb, Thomas A. Wadden. (2010) Behavioral and pharmacologic therapies for obesity. Nature Reviews Endocrinology
CrossRef38
Bilal Aijaz, Todd M. Brown, Bonnie K. Sanderson, Vera Bittner. (2010) Exercise as a Treatment for the Risk of Cardiovascular Disease. Current Treatment Options in Cardiovascular Medicine 12:4, 329-341
CrossRef39
George A. Bray. 2010. Control of Weight: How Do We Get Fat?. , 126-137.
CrossRef40
Linda Cobiac, Theo Vos, Lennert Veerman. (2010) Cost-effectiveness of Weight Watchers and the Lighten Up to a Healthy Lifestyle program. Australian and New Zealand Journal of Public Health 34:3, 240-247
CrossRef41
Lisa Fredman, Jane A. Cauley, Marc Hochberg, Kristine E. Ensrud, Gheorghe Doros, . (2010) Mortality Associated with Caregiving, General Stress, and Caregiving-Related Stress in Elderly Women: Results of Caregiver-Study of Osteoporotic Fractures. Journal of the American Geriatrics Society 58:5, 937-943
CrossRef42
Barbara Strasser, Uwe Siebert, Wolfgang Schobersberger. (2010) Resistance Training in the Treatment of the Metabolic Syndrome. Sports Medicine 40:5, 397-415
CrossRef43
Catherine G. Ling, Sheila O. Smith. (2010) Alternative placements for women wearing pedometers. Journal of the American Academy of Nurse Practitioners 22:5, 264-269
CrossRef44
Nicole Isbel. (2010) Donors at risk: obesity. Nephrology 15, S121-S132
CrossRef45
Kazumune Ueshima, Kazuko Ishikawa-Takata, Takashi Yorifuji, Etsuji Suzuki, Saori Kashima, Soshi Takao, Masumi Sugiyama, Toshiki Ohta, Hiroyuki Doi. (2010) Physical Activity and Mortality Risk in the Japanese Elderly. American Journal of Preventive Medicine 38:4, 410-418
CrossRef46
Gary O'Donovan, Anthony J. Blazevich, Colin Boreham, Ashley R. Cooper, Helen Crank, Ulf Ekelund, Kenneth R. Fox, Paul Gately, Billie Giles-Corti, Jason M. R. Gill, Mark Hamer, Ian McDermott, Marie Murphy, Nanette Mutrie, John J. Reilly, John M. Saxton, Emmanuel Stamatakis. (2010) The ABC of Physical Activity for Health: A consensus statement from the British Association of Sport and Exercise Sciences. Journal of Sports Sciences 28:6, 573-591
CrossRef47
M. Fogelholm. (2010) Physical activity, fitness and fatness: relations to mortality, morbidity and disease risk factors. A systematic review. Obesity Reviews 11:3, 202-221
CrossRef48
Benoit J. Arsenault, Jamal S. Rana, Isabelle Lemieux, Jean-Pierre Després, Nicholas J. Wareham, John J.P. Kastelein, S. Matthijs Boekholdt, Kay-Tee Khaw. (2010) Physical activity, the Framingham risk score and risk of coronary heart disease in men and women of the EPIC-Norfolk study. Atherosclerosis 209:1, 261-265
CrossRef49
L Fezeu, B Balkau, E Sobngwi, A-P Kengne, S Vol, P Ducimetiere, J-C Mbanya. (2010) Waist circumference and obesity-related abnormalities in French and Cameroonian adults: the role of urbanization and ethnicity. International Journal of Obesity 34:3, 446-453
CrossRef50
Brenda K. Edwards, Elizabeth Ward, Betsy A. Kohler, Christie Eheman, Ann G. Zauber, Robert N. Anderson, Ahmedin Jemal, Maria J. Schymura, Iris Lansdorp-Vogelaar, Laura C. Seeff, Marjolein van Ballegooijen, S. Luuk Goede, Lynn A. G. Ries. (2010) Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer 116:3, 544-573
CrossRef51
B J Arsenault, J S Rana, I Lemieux, J-P Després, J J P Kastelein, S M Boekholdt, N J Wareham, K-T Khaw. (2010) Physical inactivity, abdominal obesity and risk of coronary heart disease in apparently healthy men and women. International Journal of Obesity 34:2, 340-347
CrossRef52
Sheila F. Twinn, Gladys C.T. Lee, David R. Thompson. (2010) A Survey of Lifestyle Risk Factors for Cardiovascular Health Among Young Hong Kong Chinese Women: Implications for Long-Term Cardiovascular Health. Journal of Women's Health 19:2, 289-295
CrossRef53
Birgit Teucher, Sabine Rohrmann, Rudolf Kaaks. (2010) Obesity: Focus on all-cause mortality and cancer. Maturitas 65:2, 112-116
CrossRef54
D. ENETTE LARSON-MEYER, LEANNE REDMAN, LEONIE K. HEILBRONN, CORBY K. MARTIN, ERIC RAVUSSIN. (2010) Caloric Restriction with or without Exercise. Medicine & Science in Sports & Exercise 42:1, 152-159
CrossRef55
Konstantinos Tziomalos, Hariklia V. Dimitroula, Niki Katsiki, Christos Savopoulos, Apostolos I. Hatzitolios. (2010) Effects of Lifestyle Measures, Antiobesity Agents, and Bariatric Surgery on Serological Markers of Inflammation in Obese Patients. Mediators of Inflammation 2010, 1-14
CrossRef56
David A Beuther. (2010) Recent insight into obesity and asthma. Current Opinion in Pulmonary Medicine 16:1, 64-70
CrossRef57
Jung Su Lee, Kiyoshi Kawakubo, Katsumi Mori, Akira Akabayashi. (2010) BMI Specific Waist Circumference for Detecting Clusters of Cardiovascular Risk Factors in a Japanese Population. Journal of Atherosclerosis and Thrombosis 17:5, 468-475
CrossRef58
Jennifer W. Bea, Ellen C Cussler, Scott B. Going, Robert M. Blew, Lauve L. Metcalfe, Timothy G Lohman. (2009) Resistance Training Predicts Six-Year Body Composition Change in Postmenopausal Women. Medicine & Science in Sports & Exercise1
CrossRef59
Lorenzo M. Donini, Luciano Scavone, Claudia Savina, Cecilia Coletti, Maddalena Paolini, Settimio Tempera, Barbara Neri, Maria Rosaria Felice, Alessandro Pinto, Carlo Cannella. (2009) Sagittal abdominal diameter: comparison with waist circumference and its prediction of metabolic syndrome. Mediterranean Journal of Nutrition and Metabolism 2:3, 187-195
CrossRef60
Ineke van Dis, Daan Kromhout, Johanna M. Geleijnse, Jolanda M.A. Boer, W.M. Monique Verschuren. (2009) Body mass index and waist circumference predict both 10-year nonfatal and fatal cardiovascular disease risk: study conducted in 20 000 Dutch men and women aged 20–65 years. European Journal of Cardiovascular Prevention & Rehabilitation 16:6, 729-734
CrossRef61
S Walter, A Kunst, J Mackenbach, A Hofman, H Tiemeier. (2009) Mortality and disability: the effect of overweight and obesity. International Journal of Obesity 33:12, 1410-1418
CrossRef62
Christoph Handschin. (2009) Peroxisome proliferator-activated receptor-γ coactivator-1α in muscle links metabolism to inflammation. Clinical and Experimental Pharmacology and Physiology 36:12, 1139-1143
CrossRef63
A.R. Abubakari, W. Lauder, M.C. Jones, A. Kirk, C. Agyemang, R.S. Bhopal. (2009) Prevalence and time trends in diabetes and physical inactivity among adult West African populations: The epidemic has arrived. Public Health 123:9, 602-614
CrossRef64
David A. Beuther. (2009) Obesity and Asthma. Clinics in Chest Medicine 30:3, 479-488
CrossRef65
Faidon Magkos, Mary Yannakoulia, Jean L. Chan, Christos S. Mantzoros. (2009) Management of the Metabolic Syndrome and Type 2 Diabetes Through Lifestyle Modification. Annual Review of Nutrition 29:1, 223-256
CrossRef66
Xiaoyan Zhang, Enqing Liu, Zhen Tian, Wei Wang, Tao Ye, Gongshu Liu, Yimin Li, Ping Wang, Xilin Yang, Zhijie Yu, Gang Hu. (2009) High birth weight and overweight or obesity among Chinese children 3–6 years old. Preventive Medicine 49:2-3, 172-178
CrossRef67
Konstantinos Kantartzis, Charisis Totsikas, Hans-Ulrich Häring, Norbert Stefan. (2009) Role of ectopic fat in the pathogenesis of insulin resistance. Clinical Lipidology 4:4, 457-464
CrossRef68
Birna Bjarnason-Wehrens, Olaf Schulz, Stephan Gielen, Martin Halle, Martin Dürsch, Rainer Hambrecht, Heinz Lowis, Wilfried Kindermann, Robin Schulze, Bernhard Rauch. (2009) Leitlinie körperliche Aktivität zur Sekundärprävention und Therapie kardiovaskulärer Erkrankungen. Clinical Research in Cardiology Supplements 4:S3, 1-44
CrossRef69
Zuhra Musherraf, Anita L. Nelson. (2009) Evaluating consistency of anthropomorphic measurements in women with a history of gestational diabetes. Osteopathic Family Physician 1:1, 4-8
CrossRef70
A. Koster, T. B. Harris, S. C. Moore, A. Schatzkin, A. R. Hollenbeck, J. Th. M. van Eijk, M. F. Leitzmann. (2009) Joint Associations of Adiposity and Physical Activity With Mortality: The National Institutes of Health-AARP Diet and Health Study. American Journal of Epidemiology 169:11, 1344-1351
CrossRef71
Estefanía Toledo, Juan José Beunza, Jorge M. Núñez-Córdoba, Maira Bes-Rastrollo, Francisco Javier Basterra-Gortari, Miguel A. Martínez-González. (2009) Metabolic risk factors in a cohort of young adults and their association with a body-mass index between 22 and 25kg/m2. Medicina Clínica 132:17, 654-660
CrossRef72
T Shimazu, S Kuriyama, K Ohmori-Matsuda, N Kikuchi, N Nakaya, I Tsuji. (2009) Increase in body mass index category since age 20 years and all-cause mortality: a prospective cohort study (the Ohsaki Study). International Journal of Obesity 33:4, 490-496
CrossRef73
C. Herder, M. Peltonen, W. Koenig, K. Sütfels, J. Lindström, S. Martin, P. Ilanne-Parikka, J. G. Eriksson, S. Aunola, S. Keinänen-Kiukaanniemi, T. T. Valle, M. Uusitupa, H. Kolb, J. Tuomilehto, . (2009) Anti-inflammatory effect of lifestyle changes in the Finnish Diabetes Prevention Study. Diabetologia 52:3, 433-442
CrossRef74
L. V. Kallings, J. S. Johnson, R. M. Fisher, U. d. Faire, A. Stahle, E. Hemmingsson, M.-L. Hellenius. (2009) Beneficial effects of individualized physical activity on prescription on body composition and cardiometabolic risk factors: results from a randomized controlled trial. European Journal of Cardiovascular Prevention & Rehabilitation 16:1, 80-84
CrossRef75
Helmut Gohlke, Christian Albus, Detlef Bernd Gysan, Harry W. Hahmann, Peter Mathes. (2009) Cardiovascular Prevention in Clinical Practice (ESC and German Guidelines 2007). Herz 34:1, 4-14
CrossRef76
E. Ingelsson, J. Arnlov, J. Sundstrom, U. Riserus, K. Michaelsson, L. Byberg. (2009) Relative importance and conjoint effects of obesity and physical inactivity for the development of insulin resistance. European Journal of Cardiovascular Prevention & Rehabilitation 16:1, 28-33
CrossRef77
Jochen Klenk, Gabriele Nagel, Hanno Ulmer, Alexander Strasak, Hans Concin, Günter Diem, Kilian Rapp, . (2009) Body mass index and mortality: results of a cohort of 184,697 adults in Austria. European Journal of Epidemiology 24:2, 83-91
CrossRef78
David Trock. (2009) Tired, Achy, and Overweight, the Inflammatory Nature of Obesity. JCR: Journal of Clinical Rheumatology 15:1, 50
CrossRef79
Sebastian Schneeweiss, Soko Setoguchi, M. Alan Brookhart, Liljana Kaci, Philip S. Wang. (2009) Assessing Residual Confounding of the Association between Antipsychotic Medications and Risk of Death using Survey Data. CNS Drugs 23:2, 171-180
CrossRef80
Berit L. Heitmann, Andrew P. Hills, Peder Frederiksen, Leigh C. Ward. (2009) Obesity, Leanness, and Mortality: Effect Modification by Physical Activity in Men and Women. Obesity 17:1, 136-142
CrossRef81
Huiguang Tian, Hongxiang Xie, Guide Song, Hong Zhang, Gang Hu. (2009) Prevalence of overweight and obesity among 2.6 million rural Chinese adults. Preventive Medicine 48:1, 59-63
CrossRef82
Pischon, T., Boeing, H., Hoffmann, K., Bergmann, M., Schulze, M.B., Overvad, K., van der Schouw, Y.T., Spencer, E., Moons, K.G.M., Tjønneland, A., Halkjaer, J., Jensen, M.K., Stegger, J., Clavel-Chapelon, F., Boutron-Ruault, M.-C., Chajes, V., Linseisen, J., Kaaks, R., Trichopoulou, A., Trichopoulos, D., Bamia, C., Sieri, S., Palli, D., Tumino, R., Vineis, P., Panico, S., Peeters, P.H.M., May, A.M., Bueno-de-Mesquita, H.B., van Duijnhoven, F.J.B., Hallmans, G., Weinehall, L., Manjer, J., Hedblad, B., Lund, E., Agudo, A., Arriola, L., Barricarte, A., Navarro, C., Martinez, C., Quirós, J.R., Key, T., Bingham, S., Khaw, K.T., Boffetta, P., Jenab, M., Ferrari, P., Riboli, E., . (2008) General and Abdominal Adiposity and Risk of Death in Europe. New England Journal of Medicine 359:20, 2105-2120
Full Text83
B.-C. Zyriax, E. Windler. (2008) Idealgewicht – gibt es das?. Gynäkologische Endokrinologie 6:4, 249-256
CrossRef84
N. Orsini, R. Bellocco, M. Bottai, M. Pagano, K. Michaelsson, A. Wolk. (2008) Combined effects of obesity and physical activity in predicting mortality among men. Journal of Internal Medicine 264:5, 442-451
CrossRef85
Martha Gulati, Dina M. Sparano. (2008) Survival of the Fittest: Impact of Cardiorespiratory Fitness on Mortality, Cardiac Risk, and its Relationship with Body Mass Index in Women. Obesity Management 4:5, 222-226
CrossRef86
Niels Engberding, Nanette K Wenger. (2008) Cardiovascular disease prevention tailored for women. Expert Review of Cardiovascular Therapy 6:8, 1123-1134
CrossRef87
Xavier García-Moll Marimon. (2008) Marcadores de inflamación, función endotelial, edad e índice de masa corporal en personas sin enfermedad cardiovascular. Medicina Clínica 131:10, 378-379
CrossRef88
Gerald M. Reaven. (2008) Insulin Resistance: the Link Between Obesity and Cardiovascular Disease. Endocrinology & Metabolism Clinics of North America 37:3, 581-601
CrossRef89
L. Qi, P. Kraft, D. J. Hunter, F. B. Hu. (2008) The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women. Human Molecular Genetics 17:22, 3502-3508
CrossRef90
Mika Kivimäki, Jane E. Ferrie, G. David Batty, George Davey Smith, Marko Elovainio, Michael G. Marmot, Martin J. Shipley. (2008) Optimal Form of Operationalizing BMI in Relation to All-cause and Cause-specific Mortality: The Original Whitehall Study. Obesity 16:8, 1926-1932
CrossRef91
Patrick H Dessein, Miguel A Gonzalez-Gay, Angela J Woodiwiss, Barry I Joffe, Gavin R Norton, Ahmed Solomon. (2008) The impact of the metabolic syndrome on cardiovascular risk and disease in rheumatoid arthritis. Future Rheumatology 3:4, 335-349
CrossRef92
Christoph Handschin, Bruce M. Spiegelman. (2008) The role of exercise and PGC1α in inflammation and chronic disease. Nature 454:7203, 463-469
CrossRef93
G. A. Colditz, D. M. Winn. (2008) Criteria for the Evaluation of Large Cohort Studies: An Application to the Nurses' Health Study. JNCI Journal of the National Cancer Institute 100:13, 918-925
CrossRef94
R. Ross, T. Berentzen, A. J. Bradshaw, I. Janssen, H. S. Kahn, P. T. Katzmarzyk, J. L. Kuk, J. C. Seidell, M. B. Snijder, T. I. A. Sørensen, J-P. Després. (2008) Does the relationship between waist circumference, morbidity and mortality depend on measurement protocol for waist circumference?. Obesity Reviews 9:4, 312-325
CrossRef95
X Zhang, X-O Shu, W-H Chow, G Yang, H Li, J Gao, Y-T Gao, W Zheng. (2008) Body mass index at various ages and mortality in Chinese women: impact of potential methodological biases. International Journal of Obesity 32:7, 1130-1136
CrossRef96
P. K.-T. Li, B. C.-H. Kwan, C. C. Szeto, G. T.-C. Ko. (2008) Metabolic syndrome in peritoneal dialysis patients. NDT Plus 1:4, 206-214
CrossRef97
Marc Nocon, Theresa Hiemann, Falk Müller-Riemenschneider, Frank Thalau, Stephanie Roll, Stefan N. Willich. (2008) Association of physical activity with all-cause and cardiovascular mortality: a systematic review and meta-analysis. European Journal of Cardiovascular Prevention & Rehabilitation 15:3, 239-246
CrossRef98
Arlene Hankinson. (2008) Association of Activity and Chronic Disease Risk Factors: Utility and Limitations of Objectively Measured Physical Activity Data. Journal of the American Dietetic Association 108:6, 945-947
CrossRef99
Cristina Bianchi, Giuseppe Penno, Giuseppe Daniele, Luca Benzi, Stefano Prato, Roberto Miccoli. (2008) Optimizing management of metabolic syndrome to reduce risk: focus on life-style. Internal and Emergency Medicine 3:2, 87-98
CrossRef100
Araceli Boraita Pérez. (2008) Ejercicio, piedra angular de la prevención cardiovascular. Revista Española de Cardiología 61:5, 514-528
CrossRef101
Annemarie Koster, Kushang V. Patel, Marjolein Visser, Jacques Th. M. Van Eijk, Alka M. Kanaya, Nathalie De Rekeneire, Anne B. Newman, Frances A. Tylavsky, Stephen B. Kritchevsky, Tamara B. Harris, . (2008) Joint Effects of Adiposity and Physical Activity on Incident Mobility Limitation in Older Adults. Journal of the American Geriatrics Society 56:4, 636-643
CrossRef102
Kevin C. Oeffinger. (2008) Are survivors of acute lymphoblastic leukemia (ALL) at increased risk of cardiovascular disease?. Pediatric Blood & Cancer 50:S2, 462-467
CrossRef103
Mathieu Gayda, Carlos Brun, Martin Juneau, Sylvie Levesque, Anil Nigam. (2008) Long-term cardiac rehabilitation and exercise training programs improve metabolic parameters in metabolic syndrome patients with and without coronary heart disease. Nutrition, Metabolism and Cardiovascular Diseases 18:2, 142-151
CrossRef104
Jennifer L. Gordon, Kim L. Lavoie, André Arsenault, Blaine Ditto, Simon L. Bacon. (2008) Health behaviors and endothelial function. Journal of Behavioral Medicine 31:1, 5-21
CrossRef105
Avraham Weiss, Yichayaou Beloosesky, Mona Boaz, Alexandra Yalov, Ran Kornowski, Ehud Grossman. (2008) Body Mass Index is Inversely Related to Mortality in Elderly Subjects. Journal of General Internal Medicine 23:1, 19-24
CrossRef106
Alexander M. Kulminski, Konstantin G. Arbeev, Irina V. Kulminskaya, Svetlana V. Ukraintseva, Kenneth Land, Igor Akushevich, Anatoli I. Yashin. (2008) Body Mass Index and Nine-Year Mortality in Disabled and Nondisabled Older U.S. Individuals. Journal of the American Geriatrics Society 56:1, 105-110
CrossRef107
M Akbartabartoori, M E J Lean, C R Hankey. (2008) The associations between current recommendation for physical activity and cardiovascular risks associated with obesity. European Journal of Clinical Nutrition 62:1, 1-9
CrossRef108
RENA R. WING, JOHN JAKICIC, REBECCA NEIBERG, WEI LANG, STEVEN N. BLAIR, LAWTON COOPER, JAMES O. HILL, KAREN C. JOHNSON, CORA E. LEWIS. (2007) Fitness, Fatness, and Cardiovascular Risk Factors in Type 2 Diabetes. Medicine & Science in Sports & Exercise 39:12, 2107-2116
CrossRef109
E. Corruble. (2007) Effets cardio-vasculaires des antipsychotiques : synthèse pour le clinicien. L'Encéphale 33, 27-30
CrossRef110
H. Gohlke. (2007) Moderne Risikoanalyse bei intermediärem Risiko für kardiovaskuläre Ereignisse. Clinical Research in Cardiology Supplements 2:5, V10-V17
CrossRef111
Darren E.R. Warburton, Peter T. Katzmarzyk, Ryan E. Rhodes, Roy J. Shephard. (2007) Evidence-informed physical activity guidelines for Canadian adultsThis article is part of a supplement entitled Advancing physical activity measurement and guidelines in Canada: a scientific review and evidence-based foundation for the future of Canadian physical activity guidelines co-published by Applied Physiology, Nutrition, and Metabolism and the Canadian Journal of Public Health . It may be cited as Appl. Physiol. Nutr. Metab. 32(Suppl. 2E) or as Can. J. Public Health 98(Suppl. 2).. Applied Physiology, Nutrition, and Metabolism 32:S2E, S16-S68
CrossRef112
Jeff MP Holly, Emily J Foulstone, Claire M Perks. (2007) How growth hormone may be linked to cancer: concerns and perspective. Expert Review of Endocrinology & Metabolism 2:6, 759-771
CrossRef113
K. J. VAN STRALEN, S. LE CESSIE, F. R. ROSENDAAL, C. J. M. DOGGEN. (2007) Regular sports activities decrease the risk of venous thrombosis. Journal of Thrombosis and Haemostasis 5:11, 2186-2192
CrossRef114
Vincenzo Russo, Ernesto Ammendola, Ilaria Crescenzo, Danilo Ricciardi, Pasquale Capuano, Assunta Topatino, Ludovico Docimo, Lucio Santangelo, Raffaele Calabrò. (2007) Effect of Weight Loss following Bariatric Surgery on Myocardial Dispersion of Repolarization in Morbidly Obese Patients. Obesity Surgery 17:7, 857-865
CrossRef115
&NA;. (2007) FULL TEXT Chapter 1: Introduction. European Journal of Cardiovascular Prevention & Rehabilitation 14:Supplement 2, S2-S113
CrossRef116
J A Greenberg, K Fontaine, D B Allison. (2007) Putative biases in estimating mortality attributable to obesity in the US population. International Journal of Obesity 31:9, 1449-1455
CrossRef117
A. Tschoner, J. Engl, M. Laimer, S. Kaser, M. Rettenbacher, W. W. Fleischhacker, J. R. Patsch, C. F. Ebenbichler. (2007) Metabolic side effects of antipsychotic medication. International Journal of Clinical Practice 61:8, 1356-1370
CrossRef118
R P Gelber, T Kurth, J E Manson, J E Buring, J M Gaziano. (2007) Body mass index and mortality in men: evaluating the shape of the association. International Journal of Obesity 31:8, 1240-1247
CrossRef119
S. Stenholm, P. Sainio, T. Rantanen, S. Koskinen, A. Jula, M. Heliovaara, A. Aromaa. (2007) High Body Mass Index and Physical Impairments as Predictors of Walking Limitation 22 Years Later in Adult Finns. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 62:8, 859-865
CrossRef120
John Alan Farmer. 2007. Obesity and Inflammation. , 139-165.
CrossRef121
Anne McTiernan, Bess Sorensen, Melinda L. Irwin, Angela Morgan, Yutaka Yasui, Rebecca E. Rudolph, Christina Surawicz, Johanna W. Lampe, Paul D. Lampe, Kamran Ayub, John D. Potter. (2007) Exercise Effect on Weight and Body Fat in Men and Women*. Obesity 15:6, 1496-1512
CrossRef122
B. K. Pedersen. (2007) Body mass index-independent effect of fitness and physical activity for all-cause mortality. Scandinavian Journal of Medicine & Science in Sports 17:3, 196-204
CrossRef123
Peter Y. Liu, Ian D. Caterson, Ronald R. Grunstein, David J. Handelsman. (2007) Androgens, Obesity, and Sleep-Disordered Breathing in Men. Endocrinology & Metabolism Clinics of North America 36:2, 349-363
CrossRef124
Samuel Klein, David B. Allison, Steven B. Heymsfield, David E. Kelley, Rudolph L. Leibel, Cathy Nonas, Richard Kahn. (2007) Waist Circumference and Cardiometabolic Risk: A Consensus Statement from Shaping America’s Health: Association for Weight Management and Obesity Prevention; NAASO, The Obesity Society; the American Society for Nutrition; and the American Diabetes Association*. Obesity 15:5, 1061-1067
CrossRef125
Thomas A. Wadden, Meghan L. Butryn, Christopher Wilson. (2007) Lifestyle Modification for the Management of Obesity. Gastroenterology 132:6, 2226-2238
CrossRef126
J. S. Rana, M. Nieuwdorp, J. W. Jukema, J. J. P. Kastelein. (2007) Cardiovascular metabolic syndrome ? an interplay of, obesity, inflammation, diabetes and coronary heart disease. Diabetes, Obesity and Metabolism 9:3, 218-232
CrossRef127
Sachin Mehta, John A. Farmer. (2007) Obesity and inflammation: A new look at an old problem. Current Atherosclerosis Reports 9:2, 134-138
CrossRef128
Graham A. Colditz. (2007) Cohort studies of etiology and survival after cancer: the unique needs for uninterrupted funding. Cancer Causes & Control 18:3, 235-241
CrossRef129
Joann E. Manson, Shari S. Bassuk, Frank B. Hu, Meir J. Stampfer, Graham A. Colditz, Walter C. Willett. (2007) Estimating The Number of Deaths Due to Obesity: Can The Divergent Findings Be Reconciled?. Journal of Women's Health 16:2, 168-176
CrossRef130
Gang Hu, Timo A. Lakka, Tuomas O. Kilpeläinen, Jaakko Tuomilehto. (2007) Epidemiological studies of exercise in diabetes prevention. Applied Physiology, Nutrition, and Metabolism 32:3, 583-595
CrossRef131
Mark Hamer, Yati N. Boutcher, Stephen H. Boutcher. (2007) Fatness is related to blunted vascular stress responsivity, independent of cardiorespiratory fitness in normal and overweight men. International Journal of Psychophysiology 63:3, 251-257
CrossRef132
Manisha Chandalia, Nicola Abate. (2007) Metabolic complications of obesity: inflated or inflamed?. Journal of Diabetes and its Complications 21:2, 128-136
CrossRef133
Helmut Gohlke, Moritz Winter, Marthin Karoff, Klaus Held. (2007) CARRISMA: a new tool to improve risk stratification and guidance of patients in cardiovascular risk management in primary prevention. European Journal of Cardiovascular Prevention & Rehabilitation 14:1, 141-148
CrossRef134
Tore Christiansen, Jens M. Bruun, Erik L. Madsen, Bjørn Richelsen. (2007) Weight Loss Maintenance in Severely Obese Adults after an Intensive Lifestyle Intervention: 2- to 4-Year Follow-Up*. Obesity 15:2, 413-420
CrossRef135
Antronette K. Yancey, Jonathan E. Fielding, George R. Flores, James F. Sallis, William J. McCarthy, Lester Breslow. (2007) Creating a Robust Public Health Infrastructure for Physical Activity Promotion. American Journal of Preventive Medicine 32:1, 68-78
CrossRef136
Eleni Linos, Michelle D. Holmes, Walter C. Willett. (2007) Diet and breast cancer. Current Oncology Reports 9:1, 31-41
CrossRef137
Luc F. Van Gaal, Ilse L. Mertens, Christophe E. De Block. (2006) Mechanisms linking obesity with cardiovascular disease. Nature 444:7121, 875-880
CrossRef138
Lian Tock, Wagner L. Prado, Danielle A. Caranti, Dejaldo M.J. Cristofalo, Henrique Lederman, Mauro Fisberg, K??li O. Siqueira, S??rgio G. Stella, Hanna K. Antunes, Isa P. Cintra, S??rgio Tufik, Marco T??lio de Mello, Ana R. D??maso. (2006) Nonalcoholic fatty liver disease decrease in obese adolescents after multidisciplinary therapy. European Journal of Gastroenterology & Hepatology 18:12, 1241-1245
CrossRef139
Gang Hu, Timo A. Lakka, Hanna-Maaria Lakka, Jaakko Tuomilehto. (2006) Lifestyle Management in the Metabolic Syndrome. Metabolic Syndrome and Related Disorders 4:4, 270-286
CrossRef140
Tracey L. Weissgerber, Larry A. Wolfe, Gregory A.L. Davies, Michelle F. Mottola. (2006) Exercise in the prevention and treatment of maternal–fetal disease: a review of the literature. Applied Physiology, Nutrition, and Metabolism 31:6, 661-674
CrossRef141
Lars J. Vatten, Tom I.L. Nilsen, P??l R. Romundstad, Wenche B. Dr??yvold, Jostein Holmen. (2006) Adiposity and physical activity as predictors of cardiovascular mortality. European Journal of Cardiovascular Prevention & Rehabilitation 13:6, 909-915
CrossRef142
S. Matthijs Boekholdt, Manjinder S. Sandhu, Nicholas E. Day, Robert Luben, Sheila A. Bingham, Ron J.G. Peters, Nicholas J. Wareham, Kay-Tee Khaw. (2006) Physical activity, C-reactive protein levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC???Norfolk prospective population study. European Journal of Cardiovascular Prevention & Rehabilitation 13:6, 970-976
CrossRef143
I T Gram, T Norat, S Rinaldi, L Dossus, A Lukanova, B Téhard, F Clavel-Chapelon, C H van Gils, P A H van Noord, P H M Peeters, H B Bueno-de-Mesquita, G Nagel, J Linseisen, P H Lahmann, H Boeing, D Palli, C Sacerdote, S Panico, R Tumino, S Sieri, M Dorronsoro, J R Quirós, C A Navarro, A Barricarte, M-J Tormo, C A González, K Overvad, S Paaske Johnsen, A Olsen, A Tjønneland, R Travis, N Allen, S Bingham, K-T Khaw, P Stattin, A Trichopoulou, V Kalapothaki, T Psaltopoulou, C Casagrande, E Riboli, R Kaaks. (2006) Body mass index, waist circumference and waist–hip ratio and serum levels of IGF-I and IGFBP-3 in European women. International Journal of Obesity 30:11, 1623-1631
CrossRef144
Sandra D??Amore, Samia Mora. (2006) Gender-Specific Prediction of Cardiac Disease. Cardiology in Review 14:6, 281-285
CrossRef145
Lars J Vatten, Tom IL Nilsen, Jostein Holmen. (2006) Combined effect of blood pressure and physical activity on cardiovascular mortality. Journal of Hypertension 24:10, 1939-1946
CrossRef146
Kaan Tunceli, Kemeng Li, L. Keoki Williams. (2006) Long-Term Effects of Obesity on Employment and Work Limitations Among U.S. Adults, 1986 to 1999. Obesity 14:9, 1637-1646
CrossRef147
Michael J LaMonte, Steven N Blair. (2006) Physical activity, cardiorespiratory fitness, and adiposity: contributions to disease risk. Current Opinion in Clinical Nutrition and Metabolic Care 9:5, 540-546
CrossRef148
Jee, Sun Ha, Sull, Jae Woong, Park, Jungyong, Lee, Sang-Yi, Ohrr, Heechoul, Guallar, Eliseo, Samet, Jonathan M., . (2006) Body-Mass Index and Mortality in Korean Men and Women. New England Journal of Medicine 355:8, 779-787
Full Text149
Peter T Katzmarzyk, Cora L Craig. (2006) Independent effects of waist circumference and physical activity on all-cause mortality in Canadian women. Applied Physiology, Nutrition, and Metabolism 31:3, 271-276
CrossRef150
Antronette K. Yancey, William J. McCarthy, Gail G. Harrison, Weng Kee Wong, Judith M. Siegel, Joanne Leslie. (2006) Challenges in Improving Fitness: Results of a Community-Based, Randomized, Controlled Lifestyle Change Intervention. Journal of Women's Health 15:4, 412-429
CrossRef151
(2006) The Look AHEAD Study: A Description of the Lifestyle Intervention and the Evidence Supporting It*. Obesity 14:5, 737-752
CrossRef152
Georgia Stathopoulou, Mark B. Powers, Angela C. Berry, Jasper A. J. Smits, Michael W. Otto. (2006) Exercise Interventions for Mental Health: A Quantitative and Qualitative Review. Clinical Psychology: Science and Practice 13:2, 179-193
CrossRef153
Dennis Styne. 2006. Clinical Management of Pediatric Obesity. , 1-5.
CrossRef154
Kristi L. Storti, Jennifer S. Brach, Shannon J. FitzGerald, Clareann H. Bunker, Andrea M. Kriska. (2006) Relationships among Body Composition Measures in Community-dwelling Older Women*. Obesity 14:2, 244-251
CrossRef155
Jeff Holly, Claire Perks. (2006) Growth hormone and cancer: are we asking the right questions?*. Clinical Endocrinology 64:2, 122-124
CrossRef156
Brian K Irons, Ronald Shane Greene, Timothy A Mazzolini, Krystal L Edwards, Rebecca B Sleeper. (2006) Implications of Rosiglitazone and Pioglitazone on Cardiovascular Risk in Patients with Type 2 Diabetes Mellitus. Pharmacotherapy 26:2, 168-181
CrossRef157
R.M. van Dam. (2006) Coffee and type 2 diabetes: From beans to beta-cells. Nutrition, Metabolism and Cardiovascular Diseases 16:1, 69-77
CrossRef158
Jasper A. J. Smits, Michael J. Zvolensky. (2006) Emotional vulnerability as a function of physical activity among individuals with panic disorder. Depression and Anxiety 23:2, 102-106
CrossRef159
Leanne M Redman. (2006) Physical activity and its effects on reproduction. Reproductive BioMedicine Online 12:5, 579-586
CrossRef160
Glen E. Duncan. (2006) Exercise, fitness, and cardiovascular disease risk in type 2 diabetes and the metabolic syndrome. Current Diabetes Reports 6:1, 29-35
CrossRef161
Susan L. McElroy, Renu Kotwal. 2006. Behavioral Weight Management of Obese Patients with Mental Disorders. , 235-260.
CrossRef162
Arthur V Everitt, Sarah N Hilmer, Jennie C Brand-Miller, Hamish A Jamieson, A Stewart Truswell, Anita P Sharma, Rebecca S Mason, Brian J Morris, David G Le Couteur. (2006) Dietary approaches that delay age-related diseases. Clinical Interventions in Aging 1:1, 11-31
CrossRef163
Kevin Keenan, Chao-Min Hoe, Lori Mixson, Carol McCoy, John Coleman, Britta Mattson, Gordon Ballam, Laura Gumprecht, Keith Soper. (2005) Diabesity: A Polygenic Model of Dietary-Induced Obesity from Ad Libitum Overfeeding of Sprague–Dawley Rats and Its Modulation by Moderate and Marked Dietary Restriction. Toxicologic Pathology 33:6, 650-674
CrossRef164
Karsten Knobloch, Artur Lichtenberg, Sandra Tomaszek, Christian Hagl, Nawid Khaladj, Uwe Klima, Axel Haverich. (2005) Long-Term Physical Activity and Neurologic Function After Harvesting of the Radial Artery as T-Graft or Free Graft in Coronary Revascularization. The Annals of Thoracic Surgery 80:3, 918-921
CrossRef165
Kraus, William E., Douglas, Pamela S., . (2005) Where Does Fitness Fit In?. New England Journal of Medicine 353:5, 517-519
Full Text166
Roberto Elosua. (2005) Actividad física. Un eficiente y olvidado elemento de la prevención cardiovascular, desde la infancia hasta la vejez. Revista Española de Cardiología 58:8, 887-890
CrossRef167
Rory Curtis, Bard J. Geesaman, Peter S. DiStefano. (2005) Ageing and metabolism: drug discovery opportunities. Nature Reviews Drug Discovery 4:7, 569-580
CrossRef168
M. Krebs. (2005) Amino acid-dependent modulation of glucose metabolism in humans. European Journal of Clinical Investigation 35:6, 351-354
CrossRef169
George A. Bray, Catherine M. Champagne. (2005) Beyond Energy Balance: There Is More to Obesity than Kilocalories. Journal of the American Dietetic Association 105:5, 17-23
CrossRef170
Graham A. Colditz, Susan E. Hankinson. (2005) The Nurses' Health Study: lifestyle and health among women. Nature Reviews Cancer 5:5, 388-396
CrossRef171
Gary T. Ford, John E. Calfee, Gary Bamossy. (2005) Book Reviews. Journal of Public Policy & Marketing 24:1, 174-180
CrossRef172
Graham A Colditz, Cynthia Stein. (2005) Smoking cessation, weight gain, and lung function. The Lancet 365:9471, 1600-1601
CrossRef173
(2005) Adiposity and Physical Activity as Predictors of Mortality. New England Journal of Medicine 352:13, 1381-1384
Full Text174
Meir Stampfer. (2005) Weight Loss and Mortality: What Does the Evidence Show?. PLoS Medicine 2:6, e181
CrossRef175
Solomon, Caren G., Dluhy, Robert G., . (2004) Bariatric Surgery — Quick Fix or Long-Term Solution?. New England Journal of Medicine 351:26, 2751-2753
Full Text176
Jacobs, David R. Jr., Pereira, Mark A., . (2004) Physical Activity, Relative Body Weight, and Risk of Death among Women. New England Journal of Medicine 351:26, 2753-2755
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