Original Article
Relation of Serial Changes in Childhood Body-Mass Index to Impaired Glucose Tolerance in Young Adulthood
N Engl J Med 2004; 350:865-875February 26, 2004
- Abstract
Background
The risk of type 2 diabetes mellitus is increased in people who have low birth weights and who subsequently become obese as adults. Whether their obesity originates in childhood and, if so, at what age are unknown. Understanding the origin of obesity may be especially important in developing countries, where type 2 diabetes is rapidly increasing yet public health messages still focus on reducing childhood “undernutrition.”
Methods
We evaluated glucose tolerance and plasma insulin concentrations in 1492 men and women 26 to 32 years of age who had been measured at birth and at intervals of three to six months throughout infancy, childhood, and adolescence in a prospective, population-based study.
Results
The prevalence of impaired glucose tolerance was 10.8 percent, and that of diabetes was 4.4 percent. Subjects with impaired glucose tolerance or diabetes typically had a low body-mass index up to the age of two years, followed by an early adiposity rebound (the age after infancy when body mass starts to rise) and an accelerated increase in body-mass index until adulthood. However, despite an increase in body-mass index between the ages of 2 and 12 years, none of these subjects were obese at the age of 12 years. The odds ratio for disease associated with an increase in the body-mass index of 1 SD from 2 to 12 years of age was 1.36 (95 percent confidence interval, 1.18 to 1.57; P<0.001).
Conclusions
There is an association between thinness in infancy and the presence of impaired glucose tolerance or diabetes in young adulthood. Crossing into higher categories of body-mass index after the age of two years is also associated with these disorders.
Media in This Article
Figure 1
Summary of the Various Phases of the Cohort Study in Relation to the Age of Subjects and the Number Available for Study.Figure 2
Mean Sex-Specific Unadjusted SD Scores for Height (Panel A) and Body-Mass Index (Panel B), According to Age, for Subjects in Whom Impaired Glucose Tolerance or Diabetes Developed.Article Activity
- Article
The prevalence of type 2 diabetes mellitus is increasing rapidly in developing countries such as India.1-3 This epidemic has been attributed to what has been called “nutritional transition” (increased availability of food, reduced physical activity, and increases in obesity) — changes that are most marked in urban populations. Type 2 diabetes may originate from events initiated during fetal development and in patterns of childhood weight gain. Studies have consistently shown high rates of this disease in people who were born small but became overweight as adults.4-8 It is unclear whether the crucial phase of postnatal weight gain is in infancy, childhood, adolescence, or adulthood. Thus, longitudinal studies are required to determine the age at which preventive interventions should be initiated. We examined the incidence of impaired glucose tolerance and type 2 diabetes in a population study of young adults raised in the era of nutritional transition in India whose growth has been recorded prospectively since birth.9
Methods
Study Cohort and Follow-up
This study of pregnancy outcomes and childhood growth was begun in 1969 in a defined area of 12 km2 in South Delhi, India.10 All families living there between December 1, 1969, and November 30, 1972, were identified. Among a population of 119,799, there were 20,755 married women of reproductive age who were assessed every other month (±3 days) in order to record menstrual dates. Women who became pregnant were seen by a health visitor every 2 months (±3 days) initially and on alternate days from the 37th week of gestation. There were 9169 pregnancies, resulting in 8181 live births (8030 singletons and 151 twins), 202 stillbirths, and 867 abortions. Trained personnel recorded the weight and the length or height of the babies within 72 hours after birth; at the ages of 3, 6, 9, and 12 months (±7 days); and at 6-month intervals (±15 days) thereafter. There were several phases in this cohort study (Figure 1Figure 1
Summary of the Various Phases of the Cohort Study in Relation to the Age of Subjects and the Number Available for Study.). More than 30 percent of the cohort (2414 subjects) was lost to follow-up between the end of phase 1 and the beginning of phase 2, a time when unauthorized housing was demolished in South Delhi.At the time of recruitment, 59.9 percent of families had an income above 50 rupees per month (national average, 28.4). Only 14.9 percent of parents were illiterate (national average, 66.3). Nevertheless, 43.0 percent of families lived in only one room. Hindus were the majority religious group (84.3 percent), followed by Sikhs (11.6 percent), Christians (2.1 percent), Muslims (1.1 percent), and Jains (0.7 percent).
Current Phase of Study
From August 1998 to August 2002, we located 2584 (31.6 percent) of the initial cohort. A social worker performed home visits and recorded each subject's occupation and level of education, physical activity, and alcohol and tobacco consumption. The subjects were asked to attend a clinic after an overnight fast for further investigations. Of the 1583 subjects (61.3 percent) who agreed to participate, 57 were excluded (24 were pregnant, 2 withdrew, and 31 were unreliably linked to earlier data), leaving 1526. In comparison with the original cohort, this cohort had 7 percent more male subjects, the rate of maternal literacy was 6 percent higher, the mean birth weight was 32 g higher, and the mean birth length was 2 mm longer. The height, weight, and body-mass index (the weight in kilograms divided by the square of the height in meters) in childhood and adolescence were approximately 0.1 SD lower than in the original cohort.
The subjects' blood pressure, weight, height, waist and hip circumferences, and skinfold thicknesses (triceps and subscapular) were measured according to standardized techniques. Subjects were categorized as obese if their body-mass index was 30 or more.11 Two definitions of overweight were used, the standard World Health Organization11 cutoff value of a body-mass index of 25 and that recommended for Asians12 of 23.
A standard glucose-tolerance test with an oral 75-g anhydrous glucose load was administered.13 Plasma glucose concentrations in samples obtained after an overnight fast and 30 and 120 minutes after the ingestion of glucose (fasting, 30-minute, and 120-minute values) were analyzed by means of a glucose oxidase method (GOD-PAP, Randox) with a Beckman autoanalyzer. Aliquots of plasma were stored at –70°C for up to eight months, and insulin concentrations were measured by radioimmunoassay (Coat-a-Count insulin kit, Diagnostic Products). The intraassay and interassay coefficients of variation were less than 5 percent and less than 7.5 percent, respectively. Insulin resistance was calculated according to the homeostasis-model assessment.14
The 30-minute increment in insulin — calculated as the (30-minute insulin concentration – the fasting insulin concentration) ÷ the 30-minute glucose concentration — was used as a measure of first-phase insulin secretion.15 Impaired glucose tolerance was defined as a fasting plasma glucose concentration of less than 126 mg per deciliter (7.0 mmol per liter) and a 120-minute value of at least 141 mg per deciliter (7.8 mmol per liter); diabetes was defined as a fasting glucose concentration of at least 126 mg per deciliter or a 120-minute concentration of at least 200 mg per deciliter (11.1 mmol per liter).13
The All India Institute of Medical Sciences approved the study. Informed consent was obtained from each subject.
Statistical Analysis
Using all recorded data, not just those for subjects recruited for the current studies, we generated height, weight, and body-mass index standards so as to derive internal sex-specific SD scores (the SD score is the number of standard deviations by which an observation differs from the mean for the cohort). Recruited subjects had an average (±SD) of 23±5.5 observations between birth and the age of 21 years. We modeled the progress of the median, spread, and skewness of the measurements as age increased. For each subject we interpolated values linearly between successive SD scores to estimate SD scores at 6 months and at birthdays from 1 to 21 years of age.16 The interpolated values were used if a measurement had been made within 6 months (up to 1 year), 1 year (age of 2 years), 1.5 years (age of 3 years), and 2 years (all ages after 3 years). Back transformation provided estimates of the measurements at all these ages. The ponderal index at birth was calculated as 1000 times the weight in grams divided by the cube of the height (or the crown–heel length) in centimeters.
We calculated the age at the time of adiposity rebound — the age after infancy at which the body-mass index starts to rise — as the age in years between two and nine years at which the lowest body-mass index occurred; the analysis was restricted to 1311 subjects whose body-mass index was estimated at every birthday. Variables with skewed distributions were log-transformed. Data were analyzed with the use of multiple linear and logistic regression.
Results
Table 1Table 1
Characteristics of the Study Cohort. shows the characteristics of the 886 men and 640 women in the current sample. Most were married, college graduates (with a bachelor's degree or above), and not in manual employment. Few women drank alcohol or smoked tobacco. Almost half the subjects were overweight according to the conventional definition,11 and nearly two thirds were overweight when the Asian cutoff value was used.12 Eight of the 1526 subjects who attended the clinic had not fasted, and a further 26 declined to provide a blood sample. Fifty subjects did not complete the glucose-tolerance test and therefore could not be classified as having normal or impaired glucose tolerance or diabetes. Of the remaining 1442 subjects, 156 (10.8 percent) had impaired glucose tolerance and 63 (4.4 percent) had diabetes.
Fasting and 120-minute plasma glucose concentrations were correlated positively with age (P<0.001 for both), body-mass index (P<0.001 for both), and waist:hip ratio (P=0.001 for both). Mean 120-minute glucose values were 101 mg per deciliter (5.61 mmol per liter) in subjects who were 26 or 27 years of age, as compared with 118 mg per deciliter (6.57 mmol per liter) in those who were 31 or 32 years of age; the corresponding figures for the combined prevalence of impaired glucose tolerance and diabetes were 8.4 percent and 17.7 percent. These trends remained significantly associated with age (P<0.001) after adjustment for body-mass index and the waist:hip ratio.
As compared with subjects with normal glucose tolerance, those with impaired glucose tolerance or diabetes had higher mean values for body-mass index, waist:hip ratio, fasting and 120-minute plasma insulin concentrations, and insulin resistance (Table 2Table 2
Mean Plasma Glucose and Insulin Concentrations, Values for Body-Mass Index, and Waist:Hip Ratios According to Glucose-Tolerance Status.). The 30-minute insulin-increment values, however, were significantly lower in the subjects with diabetes or impaired glucose tolerance than in the subjects with normal glucose tolerance and were lowest in those with diabetes. The presence of impaired glucose tolerance and diabetes was unrelated to a subject's level of education or employment status, alcohol consumption, smoking status, or level of physical activity. A history of diabetes in a first-degree relative (present in 36.7 percent of subjects) was associated with an increased risk of impaired glucose tolerance or diabetes (P=0.004), but this relation was no longer statistically significant (P=0.08) after adjustment for adult body-mass index and the waist:hip ratio. In further analyses of the predictors of impaired glucose tolerance and diabetes, we adjusted for age, sex, adult body-mass index, and the waist:hip ratio unless otherwise stated.Size at Birth and during Infancy
Across the range of birth weights, 120-minute plasma glucose concentrations in the young adult subjects fell from 113 mg per deciliter (6.28 mmol per liter) in subjects with a birth weight of 2.25 kg or less to 105 mg per deciliter (5.85 mmol per liter) in those with a birth weight of more than 3.5 kg (P=0.02). This relationship was not changed by further adjustment for the length of gestation. There were similar trends in fasting insulin concentrations (P=0.02), 120-minute insulin concentrations (P=0.008), and insulin resistance (P=0.009). These variables were also inversely related to the ponderal index at birth (P=0.04, P=0.01, and P=0.03, respectively). Although the development of impaired glucose tolerance and diabetes was not related to birth weight, in combination the prevalence of these conditions was inversely related to weight and body-mass index at one year of age (P=0.04 and P=0.03, respectively; odds ratio, 1.6; 95 percent confidence interval, 1.0 to 2.5) for those in the lowest quartile of body-mass index as compared with those in the highest quartile of body-mass index at one year.
Childhood Growth and Obesity
Figure 2Figure 2
Mean Sex-Specific Unadjusted SD Scores for Height (Panel A) and Body-Mass Index (Panel B), According to Age, for Subjects in Whom Impaired Glucose Tolerance or Diabetes Developed. shows the growth of boys and girls in whom impaired glucose tolerance or diabetes subsequently developed. The SD score for the cohort is set at zero. A child maintaining a steady position as large or small in relation to other children would follow a horizontal path on the figure. The SD scores for body-mass index fell between birth and two years of age among children in whom impaired glucose tolerance or diabetes later developed, although this decrease was not statistically significant (P=0.29). From two years of age onward they had an accelerated increase in body-mass index, while SD scores for height remained relatively constant.As shown in Table 3Table 3
Prevalence of and Odds Ratios for Impaired Glucose Tolerance or Diabetes, According to the Body-Mass Index (BMI) at 2 Years and 12 Years of Age and 2 Years of Age and Currently., the highest prevalence of impaired glucose tolerance and diabetes was among subjects who were in the lowest third of the group with respect to body-mass index at the age of 2 years and the highest at the age of 12 years. In a simultaneous regression, the opposing effects of body-mass index at 2 years and at 12 years were both statistically significant (P=0.002 for body-mass index at 2 years and P<0.001 for body-mass index at 12 years, adjusted for age and sex). An increase of 1 SD in body-mass index between the ages of 2 and 12 years was associated with an odds ratio of impaired glucose tolerance or diabetes of 1.36 (95 percent confidence interval, 1.18 to 1.57; P<0.001). This finding was similar after further adjustment for current body-mass index and the waist:hip ratio (odds ratio, 1.26; 95 percent confidence interval, 1.08 to 1.48; P=0.004). An increase of 1 SD in body-mass index between 2 years of age and adulthood was associated with only a slightly higher odds ratio than that for such an increase between 2 and 12 years of age (odds ratio, 1.46; 95 percent confidence interval, 1.28 to 1.66; P<0.001, adjusted for age and sex).Using the definitions of the International Obesity Task Force,17 we found that only 3.3 percent of the children in whom impaired glucose tolerance or diabetes subsequently developed were overweight at the age of 12 years, and none were obese at this age. These figures had increased by the age of 16 years to 11.4 percent and 0.5 percent, respectively. A 1-unit increase in the body-mass index at the age of 12 years was associated with a corresponding increase of 1.4 units (95 percent confidence interval, 1.3 to 1.5) at the age of 30 years (correlation coefficient, 0.61).
Adiposity Rebound
The mean body-mass index at the time of adiposity rebound was similar in subjects in whom impaired glucose tolerance or diabetes developed and subjects whose glucose tolerance remained normal (13.8 and 13.9, respectively), but the mean age was younger (6.3 years, as compared with 6.7 years; P=0.007). Children with the earliest adiposity rebound (five years of age or younger) had the highest body-mass index in later childhood, and this difference persisted into adulthood (Table 4Table 4
Ponderal Index at Birth; Body-Mass Index at the Age of 2 Years, 12 Years, and Currently; and Prevalence of Impaired Glucose Tolerance or Diabetes, According to the Age at the Time of Adiposity Rebound.). However, they had the lowest ponderal index at birth, the lowest body-mass index at two years, and a small increase in body-mass index from birth to two years of age (P=0.004). The prevalence of impaired glucose tolerance and diabetes fell with increasing age at the time of adiposity rebound.Discussion
We studied more than 1400 adults who had grown up in the city of Delhi, India, at a time of rapid nutritional transition. Even at the age of 30 years, 15.2 percent had impaired glucose tolerance or diabetes, and 4.4 percent had diabetes. Mean 120-minute plasma glucose concentrations after a standard glucose challenge rose by 17 mg per deciliter (0.96 mmol per liter) between the ages of 26 and 32 years, indicating a sharp deterioration in glucose homeostasis at a relatively young age in adult life. The growth of children in whom impaired glucose tolerance or diabetes later developed was characterized by a low body-mass index between birth and two years of age, a young age at adiposity rebound (as defined by the age after infancy at which the body-mass index starts to rise), and a sustained accelerated gain in body-mass index until adulthood.
The study subjects came from a population of neonates representing all live births within a defined area. Since only 18.7 percent of the original cohort participated in the present study, the subjects may well be unrepresentative of the cohort as a whole. However, the differences in their mean size at birth and in childhood, though statistically significant, were trivial. Our analysis was based on internal comparisons within the study sample and would be biased only if the association between early growth and current glucose or insulin status differed between those who were included in the current study and those who were not. Some of these young adults with diabetes may not have had type 2 diabetes; however, since only one required insulin, the number with type 1 diabetes is likely to be small.
Our study had several strengths. It was population-based; gestational age was assessed prospectively; trained personnel collected anthropometric data at frequent intervals; and the relatively young age of subjects ensured minimal modification as a result of complications of disease or medications. The cohort is unique, in that it represents an urban population of people who grew up during a period of rapid nutritional transition in a developing country and who are now having a rapid loss of glucose homeostasis relatively young in adult life.
The mean insulin concentrations in our cohort would be considered high in whites with similar values for body-mass index in Western countries, but such values have been well described in South Asians.18,19 As in earlier reports,4,8,20 we also found that a small size at birth, defined by a low birth weight or ponderal index, was associated with increased plasma glucose and insulin concentrations and insulin resistance during adulthood. It was not, however, associated with the occurrence of impaired glucose tolerance or diabetes in our study. Given the association between birth weight and both fasting and 120-minute glucose concentrations, the lack of a significant association with disease may be due to a loss of sensitivity resulting in the change from a continuous to a dichotomous variable. Consistent with studies in Hertfordshire, United Kingdom,4 and Helsinki, Finland,21 we found that low weight and thinness at one to two years of age were associated with impaired glucose tolerance and diabetes in adulthood. Children who are thin at two years of age tend to have been thin at birth, though postnatal influences such as infection and feeding practices also contribute.
The children in whom impaired glucose tolerance or diabetes later developed were not overweight or obese in childhood. They remained below the cohort average for body-mass index until the age of 10 years. At the age of 12 years, only 3.3 percent were overweight according to the current definitions, and none were obese. Instead, they were characterized by their high rate of gain in body mass after the age of two years. We propose that an upward trajectory of body-mass index, starting in early childhood, underlies the current epidemic of diabetes in India.
Our findings are remarkably similar to those in the only Western population with comparable data.21 Among 8760 boys and girls who grew up in Helsinki, Finland, during the Second World War, childhood obesity was uncommon, affecting only 0.4 percent at the age of 12 years, according to International Obesity Task Force definitions.17 The 290 children in that study in whom type 2 diabetes developed in adult life had below-average body size at birth and low weight at one year of age. Thereafter, they had an early adiposity rebound and an accelerated gain in weight and body-mass index, but not height. Their mean body-mass index did not exceed the average for the cohort until around five years of age. Early adiposity rebound was associated with low weight and body-mass index at one year of age. The prevalence of type 2 diabetes fell progressively from 8.6 percent in people whose adiposity rebound occurred before the age of five years to 1.8 percent in those in whom it occurred after seven years.
In conclusion, the young adults in our study who had impaired glucose tolerance or diabetes were, as a group, overweight. They were not, however, overweight as young children but, rather, became overweight as a result of an accelerated gain in body mass starting in early childhood, having been thin in infancy. The ability of children to have an accelerated increase in body mass may be a recent phenomenon in India, a consequence of nutritional transition. Our data do not allow us to distinguish between the events that lead to increasing body-mass index and the expression of the diabetic phenotype. However, assuming that the change in body-mass index is causal rather than the result of a simple association, we speculate that the primary prevention of the epidemic of diabetes in India may require measures to prevent children from crossing into higher categories of body-mass index after the age of two years. Individual children will need to have serial measurements of body-mass index for such a growth trajectory to be identified.
Supported by a grant (RG 98001) from the British Heart Foundation. The original cohort studies were supported by the National Center for Health Statistics and the Indian Council of Medical Research.
We are indebted to the men and women and their families who took part in the study, as well as to the field and laboratory staff for their contribution.
Source Information
From the Department of Pediatrics, Sunder Lal Jain Hospital, Delhi, India (S.K.B.); the Department of Pediatrics, Maulana Azad Medical College (H.S.S., S.R.), the Department of Cardiology, All India Institute of Medical Sciences (R.L., D.P., K.S.R.), and the Indian Council of Medical Research (S.K.D.B.) — all in New Delhi, India; and the Medical Research Council Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, United Kingdom (C.H.D.F., C.O., D.J.P.B.).
Address reprint requests to Prof. Sachdev at E-6/12 Vasant Vihar, New Delhi 110 057, India, or at hpssachdev@hotmail.com.
- References
References
1
King H ,Aubert RE ,Herman WH . Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998;21:1414-1431
CrossRef | Web of Science | Medline2
Pradeepa R ,Mohan V . The changing scenario of the diabetes epidemic: implications for India. Indian J Med Res 2002;116:121-132
Web of Science | Medline3
Ramachandran A ,Snehalatha C ,Latha E ,Vijay V ,Viswanathan M . Rising prevalence of NIDDM in an urban population in India. Diabetologia 1997;40:232-237
CrossRef | Web of Science | Medline4
Hales CN ,Barker DJP ,Clark PMS , et al. Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 1991;303:1019-1022
CrossRef | Web of Science | Medline5
Rich-Edwards JW ,Colditz GA ,Stampfer MJ , et al. Birthweight and the risk of type 2 diabetes mellitus in adult women. Ann Intern Med 1999;130:278-284
Web of Science | Medline6
Forsen T ,Eriksson J ,Tuomilehto J ,Reunanen A ,Osmond C ,Barker D . The fetal and childhood growth of persons who develop type 2 diabetes. Ann Intern Med 2000;133:176-182
Web of Science | Medline7
Delisle H. Programming of chronic disease by impaired fetal nutrition: evidence and implications for policy and intervention strategies. Geneva: World Health Organization, 2002. (WHO/NHD/02.3, WHO/NPH/02.1.)
8
Newsome CA ,Shiell AW ,Fall CHD ,Phillips DIW ,Shier R ,Law CM . Is birth weight related to later glucose and insulin metabolism? A systematic review. Diabet Med 2003;20:339-348
CrossRef | Web of Science | Medline9
Sachdev HPS . Recent transitions in anthropometric profile of Indian children: clinical and public health implications. NFI Bull 2003;24:6-810
Ghosh S, Bhargava SK, Moriyama IM. Longitudinal study of the survival and outcome of a birth cohort. New Delhi, India: Department of Paediatrics, Safdarjung Hospital, 1979.
11
Physical status: the use and interpretation of anthropometry: report of a WHO expert committee. World Health Organ Tech Rep Ser 1995;854:329-329
12
The Asia-Pacific perspective: redefining obesity and its treatment. Sydney, Australia: Health Communications Australia, 2000:18.
13
Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation. Part 1. Diagnosis and classification of diabetes mellitus. Geneva: World Health Organization, 1999. (WHO/NCD/NCS/99.2.)
14
Matthews DR ,Hosker JP ,Rudenski AS ,Naylor BA ,Treacher DF ,Turner RC . Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-419
CrossRef | Web of Science | Medline15
Wareham NJ ,Phillips DIW ,Byrne CD ,Hales CN . The 30-minute insulin incremental response in an oral glucose tolerance test as a measure of insulin secretion. Diabet Med 1995;12:931-931
CrossRef | Medline16
Royston P . Constructing time-specific reference ranges. Stat Med 1991;10:675-690
CrossRef | Web of Science | Medline17
Cole TJ ,Bellizzi MC ,Flegal DM ,Dietz WH . Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000;320:1240-1243
CrossRef | Web of Science | Medline18
Fall CHD ,Stein CE ,Kumaran K , et al. Size at birth, maternal weight, and type 2 diabetes in South India. Diabet Med 1998;15:220-227
CrossRef | Web of Science | Medline19
Yajnik CS . The lifecycle effects of nutrition and body size on adult adiposity, diabetes and cardiovascular disease. Obes Rev 2002;3:217-224
CrossRef | Medline20
Barker DJP ,Hales CN ,Fall CHD ,Osmond C ,Phipps K ,Clark PMS . Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidemia (syndrome X): relation to reduced fetal growth. Diabetologia 1993;36:62-67
CrossRef | Web of Science | Medline21
Eriksson JG ,Forsen T ,Tuomilehto J ,Osmond C ,Barker DJP . Early adiposity rebound in childhood and risk of Type 2 diabetes in adult life. Diabetologia 2003;46:190-194
Web of Science | Medline
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1
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Full Text8
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S Shankaran, C Bann, A Das, B Lester, H Bada, C R Bauer, L La Gasse, R D Higgins. (2011) Risk for obesity in adolescence starts in early childhood. Journal of Perinatology 31:11, 711-716
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CrossRef12
Jonathan C.K. Wells, Jay T. Stock. (2011) Re-examining heritability: genetics, life history and plasticity. Trends in Endocrinology & Metabolism 22:10, 421-428
CrossRef13
Yingkui Yang, Min Chen, David McPherson, Vinod Mishra, Carroll M. Harmon. (2011) Structural insight into the role of the human melanocortin 3 receptor cysteine residues on receptor function. Peptides
CrossRef14
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CrossRef15
Lauren B. Sherar, Joe C. Eisenmann, Philip D. Chilibeck, Nazeem Muhajarine, Susanna Martin, Donald A. Bailey, Adam D.G. Baxter-Jones. (2011) Relationship Between Trajectories of Trunk Fat Mass Development in Adolescence and Cardiometabolic Risk in Young Adulthood. Obesity 19:8, 1699-1706
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David Fraguas, Christoph U. Correll, Jessica Merchán-Naranjo, Marta Rapado-Castro, Mara Parellada, Carmen Moreno, Celso Arango. (2011) Efficacy and safety of second-generation antipsychotics in children and adolescents with psychotic and bipolar spectrum disorders: Comprehensive review of prospective head-to-head and placebo-controlled comparisons. European Neuropsychopharmacology 21:8, 621-645
CrossRef17
2011. References. , 189-202.
CrossRef18
Adriano M Pimenta, Juan-José Beunza, Almudena Sanchez-Villegas, Maira Bes-Rastrollo, Miguel A Martinez-Gonzalez. (2011) Childhood underweight, weight gain during childhood to adolescence/young adulthood and incidence of adult metabolic syndrome in the SUN (Seguimiento Universidad de Navarra) Project. Public Health Nutrition 14:07, 1237-1244
CrossRef19
Mark Hanson, Keith M. Godfrey, Karen A. Lillycrop, Graham C. Burdge, Peter D. Gluckman. (2011) Developmental plasticity and developmental origins of non-communicable disease: Theoretical considerations and epigenetic mechanisms. Progress in Biophysics and Molecular Biology 106:1, 272-280
CrossRef20
Kara Calkins, Sherin U. Devaskar. (2011) Fetal Origins of Adult Disease. Current Problems in Pediatric and Adolescent Health Care 41:6, 158-176
CrossRef21
Lisa Jahns, Linda Adair, Thomas Mroz, Barry M. Popkin. (2011) The declining prevalence of overweight among Russian children: Income, diet, and physical activity behavior changes. Economics & Human Biology
CrossRef22
Michele Wen-Chien Campbell, Joanne Williams, John B. Carlin, Melissa Wake. (2011) Is the adiposity rebound a rebound in adiposity?. International Journal of Pediatric Obesity 6:2-2, e207-e215
CrossRef23
Rachael W. Taylor, Sheila M. Williams, Philippa J. Carter, Ailsa Goulding, David F. Gerrard, Barry J. Taylor. (2011) Changes in fat mass and fat-free mass during the adiposity rebound: FLAME study. International Journal of Pediatric Obesity 6:2-2, e243-e251
CrossRef24
J. A. McKay, J. C. Mathers. (2011) Diet induced epigenetic changes and their implications for health. Acta Physiologica 202:2, 103-118
CrossRef25
Rexford S. Ahima. (2011) Digging deeper into obesity. Journal of Clinical Investigation 121:6, 2076-2079
CrossRef26
Anoop Misra, Neha Singhal, B. Sivakumar, Namita Bhagat, Abhishek Jaiswal, Lokesh Khurana. (2011) Nutrition Transition in India: Secular Trends in Dietary Intake and their Relationship to Diet-related Non-communicable Diseases. Journal of Diabetesno-no
CrossRef27
Shannon L. Haley, Laurie J. Moyer-Mileur, Robert H. Lane, Lisa A. Joss-Moore. 2011. Maternal Nutrition and Developmental Outcomes. , 189-208.
CrossRef28
Sonjia Kenya, Qing He, Robert Fullilove, Donald P. Kotler. (2011) Developing an Objective Evaluation Method to Estimate Diabetes Risk in Community-Based Settings. Diabetes Technology & Therapeutics 13:5, 557-561
CrossRef29
A.A.M. Silva, C.J.N. Santos, H. Amigo, M.A. Barbieri, P. Bustos, H. Bettiol, R.J. Rona. (2011) Birth weight, current body mass index, and insulin sensitivity and secretion in young adults in two Latin American populations. Nutrition, Metabolism and Cardiovascular Diseases
CrossRef30
Mark D. Huffman, Dorairaj Prabhakaran, Clive Osmond, Caroline H.D. Fall, Nikhil Tandon, Ramakrishnan Lakshmy, Siddharth Ramji, Anita Khalil, Tarun Gera, Poornima Prabhakaran, S.K. Dey Biswas, K. Srinath Reddy, Santosh K. Bhargava, Harshpal S. Sachdev. (2011) Incidence of Cardiovascular Risk Factors in an Indian Urban Cohort. Journal of the American College of Cardiology 57:17, 1765-1774
CrossRef31
Nina Vuorela, Marja-Terttu Saha, Matti K Salo. (2011) Toddlers get slimmer while adolescents get fatter - BMI distribution in five birth cohorts from four decades in Finland. Acta Paediatrica 100:4, 570-577
CrossRef32
2011. References. , 283-360.
CrossRef33
M. M. Slining, C. W. Kuzawa, E. J. Mayer-Davis, L. S. Adair. (2011) Evaluating the Indirect Effect of Infant Weight Velocity on Insulin Resistance in Young Adulthood: A Birth Cohort Study From the Philippines. American Journal of Epidemiology 173:6, 640-648
CrossRef34
Eberhard Ritz, Kerstin Amann, Nadezda Koleganova, Kerstin Benz. (2011) Prenatal programming—effects on blood pressure and renal function. Nature Reviews Nephrology 7:3, 137-144
CrossRef35
Anna Alisi, Stefano Cianfarani, Melania Manco, Carlo Agostoni, Valerio Nobili. (2011) Non-alcoholic fatty liver disease and metabolic syndrome in adolescents: Pathogenetic role of genetic background and intrauterine environment. Annals of Medicine1-12
CrossRef36
R. Lakshmy, C. H. Fall, H. S. Sachdev, C. Osmond, D. Prabhakaran, S. D. Biswas, N. Tandon, S. Ramji, K. S. Reddy, D. J. Barker, S. K. Bhargava. (2011) Childhood body mass index and adult pro-inflammatory and pro-thrombotic risk factors: data from the New Delhi birth cohort. International Journal of Epidemiology 40:1, 102-111
CrossRef37
Ian M. Paul, Jennifer S. Savage, Stephanie L. Anzman, Jessica S. Beiler, Michele E. Marini, Jennifer L. Stokes, Leann L. Birch. (2011) Preventing Obesity during Infancy: A Pilot Study. Obesity 19:2, 353-361
CrossRef38
Rebecca Simmons. (2011) Epigenetics and maternal nutrition: nature v. nurture. Proceedings of the Nutrition Society 70:01, 73-81
CrossRef39
C. H. Fall, J. B. Borja, C. Osmond, L. Richter, S. K. Bhargava, R. Martorell, A. D. Stein, F. C. Barros, C. G. Victora, . (2011) Infant-feeding patterns and cardiovascular risk factors in young adulthood: data from five cohorts in low- and middle-income countries. International Journal of Epidemiology 40:1, 47-62
CrossRef40
L. M. Richter, C. G. Victora, P. C. Hallal, L. S. Adair, S. K. Bhargava, C. H. Fall, N. Lee, R. Martorell, S. A. Norris, H. S. Sachdev, A. D. Stein, . (2011) Cohort Profile: The Consortium of Health-Orientated Research in Transitioning Societies. International Journal of Epidemiology
CrossRef41
Jonathan C.K. Wells. (2011) The thrifty phenotype: An adaptation in growth or metabolism?. American Journal of Human Biology 23:1, 65-75
CrossRef42
Lakshmy Ramakrishnan, Harshpal S Sachdev, Meenakshi Sharma, Ransi Abraham, Swami Prakash, Dileep Gupta, Yogendra Singh, Seema Bhaskar, Shikha Sinha, Giriraj R Chandak, Kolli S Reddy, Bhargava Santosh. (2011) Relationship of APOA5, PPARγ and HL gene variants with serial changes in childhood body mass index and coronary artery disease risk factors in young adulthood. Lipids in Health and Disease 10:1, 68
CrossRef43
K Suzuki, N Kondo, M Sato, T Tanaka, D Ando, Z Yamagata. (2011) Gender differences in the association between maternal smoking during pregnancy and childhood growth trajectories: multilevel analysis. International Journal of Obesity 35:1, 53-59
CrossRef44
Chiaki Tanaka, Shigeho Tanaka, Takafumi Ando. (2011) Japan Journal of Human Growth and Development Research:51, 37-45
CrossRef45
Siddarth Ramji. 2011. Prevention and management of protein energy malnutrition. , 292-309.
CrossRef46
Anura Kurpad, Sumathi Swaminathan. 2011. Prevention and management of overweight and obesity in children. , 341-371.
CrossRef47
Christopher W. Kuzawa, Pedro C. Hallal, Linda Adair, Santosh K. Bhargava, Caroline H.D. Fall, Nanette Lee, Shane A. Norris, Clive Osmond, Manuel Ramirez-zea, Harshpal Singh Sachdev, Aryeh D. Stein, Cesar G. Victora, . (2011) Birth weight, postnatal weight gain, and adult body composition in five low and middle income countries. American Journal of Human Biologyn/a-n/a
CrossRef48
Muhammad Umair Mushtaq, Sibgha Gull, Hussain Muhammad Abdullah, Ubeera Shahid, Mushtaq Ahmad Shad, Javed Akram. (2011) Waist circumference, waist-hip ratio and waist-height ratio percentiles and central obesity among Pakistani children aged five to twelve years. BMC Pediatrics 11:1, 105
CrossRef49
G. V. Krishnaveni, S. R. Veena, A. K. Wills, J. C. Hill, S. C. Karat, C. H. D. Fall. (2010) Adiposity, insulin resistance and cardiovascular risk factors in 9–10-year-old Indian children: relationships with birth size and postnatal growth. Journal of Developmental Origins of Health and Disease 1:06, 403-411
CrossRef50
Yuki Sato, Emiko Warabisako, Hirohide Yokokawa, Shohei Harada, Masahiko Tsuda, Reiko Horikawa, Yoshihiko Kurokawa, Tomoo Okada, Noriko Ishizuka, Yoko Kobayashi, Mikiko Kishi, Tosei Takahashi, Yoshiko Kasahara, Nobuo Imazeki, Akira Senoo, Shuji Inoue. (2010) High cardiovascular risk factors among obese children in an urban area of Japan. Obesity Research & Clinical Practice 4:4, e333-e337
CrossRef51
Michael S. Boyne, Clive Osmond, Raphael A. Fraser, Marvin Reid, Carolyn Taylor-Bryan, Suzanne Soares-Wynter, Terrence E. Forrester. (2010) Developmental origins of cardiovascular risk in Jamaican children: The Vulnerable Windows Cohort Study. British Journal of Nutrition 104:07, 1026-1033
CrossRef52
Masahiro Nishihara, Mina Sonoda, Katsura Matsunami, Keiko Yanagihara, Naohiro Yonemoto, Shinobu Ida, Fumihiko Namba, Iichiro Shimomura, Itaru Yanagihara, Masako Waguri. (2010) Birth Length is a Predictor of Adiponectin Levels in Japanese Young Children. Journal of Pediatric Endocrinology and Metabolism 23:9, 913-920
CrossRef53
Karri Silventoinen, Johan Sundström, Per Tynelius, Johan Eriksson, Finn Rasmussen. (2010) Ethnic differences in blood pressure in young men living in similar environment: a study of international adoptees in Sweden. Journal of Hypertension 28:7, 1393-1399
CrossRef54
Frances Rice, Anita Thapar. (2010) Estimating the relative contributions of maternal genetic, paternal genetic and intrauterine factors to offspring birth weight and head circumference. Early Human Development 86:7, 425-432
CrossRef55
Nick Brown, Chaniyil Krishnan Sasidharan, David Fisher. (2010) Early growth and markers of cardiovascular risk in Keralan children in the Integrated Child Development Scheme. Public Health Nutrition 13:07, 1042-1048
CrossRef56
Yu-Kang Tu, Andrew Woolston, Paul D. Baxter, Mark S. Gilthorpe. (2010) Assessing the Impact of Body Size in Childhood and Adolescence on Blood Pressure. Epidemiology 21:4, 440-448
CrossRef57
Leticia Elizondo-Montemayor, Mónica Serrano-González, Patricia A. Ugalde-Casas, Carlos Cuello-García, José R. Borbolla-Escoboza. (2010) Metabolic Syndrome Risk Factors Among a Sample of Overweight and Obese Mexican Children. The Journal of Clinical Hypertension 12:5, 380-387
CrossRef58
Mukesh Gupta, Zaheer, Rakesh Jora, Vijay Kaul, Rajeev Gupta. (2010) Breast feeding and insulin levels in low birth weight neonates: A randomized study. The Indian Journal of Pediatrics 77:5, 509-513
CrossRef59
Angela L. Duckworth, Eli Tsukayama, Andrew B. Geier. (2010) Self-controlled children stay leaner in the transition to adolescence. Appetite 54:2, 304-308
CrossRef60
K. E. Yun, H. S. Park, Y. M. Song, S. I. Cho. (2010) Increases in body mass index over a 7-year period and risk of cause-specific mortality in Korean men. International Journal of Epidemiology 39:2, 520-528
CrossRef61
Christoph U Correll, Eva M Sheridan, Melissa P DelBello. (2010) Antipsychotic and mood stabilizer efficacy and tolerability in pediatric and adult patients with bipolar I mania: a comparative analysis of acute, randomized, placebo-controlled trials. Bipolar Disorders 12:2, 116-141
CrossRef62
Shazhan Amed, Denis Daneman, Farid H Mahmud, Jill Hamilton. (2010) Type 2 diabetes in children and adolescents. Expert Review of Cardiovascular Therapy 8:3, 393-406
CrossRef63
Reid F. Thompson, Francine H. Einstein. (2010) Epigenetic Basis for Fetal Origins of Age-Related Disease. Journal of Women's Health 19:3, 581-587
CrossRef64
Prema Ramachandran. (2010) Nutrition and child survival in India. The Indian Journal of Pediatrics 77:3, 301-305
CrossRef65
Ji Li, Neal H. Hooker. (2010) Childhood Obesity and Schools: Evidence From the National Survey of Children's Health. Journal of School Health 80:2, 96-103
CrossRef66
Hung-Tien Kuo, Neda Poommipanit, Marcelo Sampaio, Pavani Reddy, Yong W. Cho, Suphamai Bunnapradist. (2010) Risk Factors for Development of New-Onset Diabetes Mellitus in Pediatric Renal Transplant Recipients: An Analysis of the OPTN/UNOS Database. Transplantation 89:4, 434-439
CrossRef67
Palany Raghupathy, Belavendra Antonisamy, Finney S. Geethanjali, Julia Saperia, Samantha D. Leary, G. Priya, Joseph Richard, David J.P. Barker, Caroline H.D. Fall. (2010) Glucose tolerance, insulin resistance and insulin secretion in young south Indian adults: Relationships to parental size, neonatal size and childhood body mass index. Diabetes Research and Clinical Practice 87:2, 283-292
CrossRef68
Ian M. Paul, Lindsay Camera, Robert S. Zeiger, Theresa W. Guilbert, Leonard B. Bacharier, Lynn M. Taussig, Wayne J. Morgan, Ronina A. Covar, Marzena Krawiec, Gordon R. Bloomberg, David T. Mauger, . (2010) Relationship between infant weight gain and later asthma. Pediatric Allergy and Immunology 21:1-Part-I, 82-89
CrossRef69
Yoolwon Jeong, Kyunghee Jung-Choi, Jin Hwa Lee, Hwa Young Lee, Eun Ae Park, Young Ju Kim, Eunhee Ha, Se-Young Oh, Hyesook Park. (2010) Body Weight at Birth and at Age Three and Respiratory Illness in Preschool Children. Journal of Preventive Medicine and Public Health 43:5, 369
CrossRef70
E. M. Luque, V. P. Carlini, L. M. Vincenti, P. Puechagut, G. Stutz, M. E. Santillán, R. D. Ruiz, A. C. Martini, M. Fiol de Cuneo. (2010) Effects of hexarelin (a ghrelin analogue) on fertilisation and the pre- and postnatal development of mice. Reproduction, Fertility and Development 22:6, 926
CrossRef71
Tong-yan Han, Xin-li Wang, Yun-pu Cui, Hong-mao Ye, Xiao-mei Tong, Mei-hua Piao. (2010) No Weight Catch-Up Growth of SGA Infants Is Associated with Impaired Insulin Sensitivity during the Early Postnatal Period. International Journal of Pediatrics 2010, 1-5
CrossRef72
Hye-Kyung Chung, Hae-Young Lee. (2010) The Concepts of Weight Control and Dietary Behavior in High School Seniors. The Korean Journal of Nutrition 43:6, 607
CrossRef73
Han Gyu Kim, Goh-woon Lim, Hae Soon Kim, Young Mi Hong. (2010) Effects of a 12-week, school-based obesity management program on obese primary school children. Korean Journal of Pediatrics 53:3, 335
CrossRef74
Peter T. Ellison. (2010) Fetal programming and fetal psychology. Infant and Child Development 19:1, 6-20
CrossRef75
Otto W. B. Schult, Ludwig E. Feinendegen, Stephan Zaum, Walton W. Shreeve, Richard N. Pierson. (2010) Applications of BMI or BSI: Differences and Revisions According to Age and Height. Journal of Obesity 2010, 1-9
CrossRef76
D A González, A Nazmi, C G Victora. (2010) Growth from birth to adulthood and abdominal obesity in a Brazilian birth cohort. International Journal of Obesity 34:1, 195-202
CrossRef77
Emily J. McAllister, Nikhil V. Dhurandhar, Scott W. Keith, Louis J. Aronne, Jamie Barger, Monica Baskin, Ruth M. Benca, Joseph Biggio, Mary M. Boggiano, Joe C. Eisenmann, Mai Elobeid, Kevin R. Fontaine, Peter Gluckman, Erin C. Hanlon, Peter Katzmarzyk, Angelo Pietrobelli, David T. Redden, Douglas M. Ruden, Chenxi Wang, Robert A. Waterland, Suzanne M. Wright, David B. Allison. (2009) Ten Putative Contributors to the Obesity Epidemic. Critical Reviews in Food Science and Nutrition 49:10, 868-913
CrossRef78
Giuseppe Fatati, Eva Mirri, Stefano Coaccioli. (2009) Effects of visceral fat accumulation in obesity and type 2 diabetes. Mediterranean Journal of Nutrition and Metabolism 2:2, 111-118
CrossRef79
Vivekanand Jha. (2009) Current Status of Chronic Kidney Disease Care in Southeast Asia. Seminars in Nephrology 29:5, 487-496
CrossRef80
James Cox, Sarah Williams, Kevin Grove, Robert H. Lane, Kjersti M. Aagaard-Tillery. (2009) A maternal high-fat diet is accompanied by alterations in the fetal primate metabolome. American Journal of Obstetrics and Gynecology 201:3, 281.e1-281.e9
CrossRef81
Mary Beth Terry, Julie Flom, Parisa Tehranifar, Ezra Susser. (2009) The role of birth cohorts in studies of adult health: the New York women's birth cohort. Paediatric and Perinatal Epidemiology 23:5, 431-445
CrossRef82
Shaoyan Zhang, Christos Tjortjis, Xiaojun Zeng, Hong Qiao, Iain Buchan, John Keane. (2009) Comparing data mining methods with logistic regression in childhood obesity prediction. Information Systems Frontiers 11:4, 449-460
CrossRef83
Camila Corvalán, Juliana Kain, Gerardo Weisstaub, Ricardo Uauy. (2009) Impact of growth patterns and early diet on obesity and cardiovascular risk factors in young children from developing countries. Proceedings of the Nutrition Society 68:03, 327
CrossRef84
Rebecca A. Simmons. (2009) Developmental Origins of Adult Disease. Pediatric Clinics of North America 56:3, 449-466
CrossRef85
Yingkui Yang, Minying Cai, Min Chen, Hongchang Qu, David McPherson, Victor Hruby, Carroll M. Harmon. (2009) Key amino acid residues in the melanocortin-4 receptor for nonpeptide THIQ specific binding and signaling. Regulatory Peptides 155:1-3, 46-54
CrossRef86
M. Gamborg, P. K. Andersen, J. L. Baker, E. Budtz-Jorgensen, T. Jorgensen, G. Jensen, T. I. A. Sorensen. (2009) Life Course Path Analysis of Birth Weight, Childhood Growth, and Adult Systolic Blood Pressure. American Journal of Epidemiology 169:10, 1167-1178
CrossRef87
C.M. Schooling, T.H. Lam, E.D. Janus, B.J. Cowling, G.M. Leung, . (2009) A socio-historical hypothesis for the diabetes epidemic in Chinese-Preliminary observations from Hong Kong as a natural experiment. American Journal of Human Biology 21:3, 346-353
CrossRef88
Susanne Holzhauer, Anita C.S. Hokken Koelega, Maria de Ridder, Albert Hofman, Henriette A. Moll, Eric A.P. Steegers, Jacqueline C.M. Witteman, Vincent W.V. Jaddoe. (2009) Effect of birth weight and postnatal weight gain on body composition in early infancy. Early Human Development 85:5, 285-290
CrossRef89
Jonathan C. K. Wells. (2009) Historical cohort studies and the early origins of disease hypothesis: making sense of the evidence. Proceedings of the Nutrition Society 68:02, 179
CrossRef90
M.K. Salonen, E. Kajantie, C. Osmond, T. Forsén, H. Ylihärsilä, M. Paile-Hyvärinen, D.J.P. Barker, J.G. Eriksson. (2009) Childhood growth and future risk of the metabolic syndrome in normal-weight men and women. Diabetes & Metabolism 35:2, 143-150
CrossRef91
Aydin Nazmi, David C. Gonzalez, Isabel O. Oliveira, Bernardo L. Horta, Denise P. Gigante, Cesar G. Victora. (2009) Life course weight gain and C-reactive protein levels in young adults: Findings from a Brazilian birth cohort. American Journal of Human Biology 21:2, 192-199
CrossRef92
N. Lammi, E. Moltchanova, P. A. Blomstedt, J. Tuomilehto, J. G. Eriksson, M. Karvonen. (2009) Childhood BMI trajectories and the risk of developing young adult-onset diabetes. Diabetologia 52:3, 408-414
CrossRef93
Abdullah Al Mamun, Susanna M. Cramb, Michael J. O'Callaghan, Gail M. Williams, Jake M. Najman. (2009) Childhood Overweight Status Predicts Diabetes at Age 21 Years: A Follow-up Study. Obesity
CrossRef94
Ricardo Uauy, Camila Corvalan, Alan D. Dangour. (2009) Rank Prize Lecture Global nutrition challenges for optimal health and well-being. Proceedings of the Nutrition Society 68:01, 34
CrossRef95
Anoop Misra, Lokesh Khurana, Sumit Isharwal, Swati Bhardwaj. (2009) South Asian diets and insulin resistance. British Journal of Nutrition 101:04, 457
CrossRef96
Marçal Rossi, Ary Serpa Neto, Felipe Martin Bianco Rossi, Rodrigo Dal Moro Amarante, Geraldo Chaves Alcântara, Renato Barretto Ferreira da Silva, Paulo Fernando Regina. (2009) Percentage of excess BMI lost correlates better with improvement of metabolic syndrome after Roux-en-Y gastric bypass in morbidly obese subjects: anthropometric indexes and gastric bypass. Surgery for Obesity and Related Diseases 5:1, 11-18
CrossRef97
Tazeen H. Jafar. (2009) Children, Obesity, and High Blood Pressure: Asian Populations at High Risk. American Journal of Hypertension 22:1, 6-7
CrossRef98
Sheila M. Williams, Ailsa Goulding. (2008) Patterns of Growth Associated With the Timing of Adiposity Rebound. Obesity
CrossRef99
A. M. Corson, J. Laws, A. Laws, J. C. Litten, I. J. Lean, L. Clarke. (2008) Percentile growth charts for biomedical studies using a porcine model. animal 2:12, 1795
CrossRef100
P D Gluckman, M A Hanson. (2008) Developmental and epigenetic pathways to obesity: an evolutionary-developmental perspective. International Journal of Obesity 32, S62-S71
CrossRef101
J. J. Miranda, S. Kinra, J. P. Casas, G. Davey Smith, S. Ebrahim. (2008) Non-communicable diseases in low- and middle-income countries: context, determinants and health policy. Tropical Medicine & International Health 13:10, 1225-1234
CrossRef102
V. S. Ajay, D. Prabhakaran, P. Jeemon, K. R. Thankappan, V. Mohan, L. Ramakrishnan, P. Joshi, F. U. Ahmed, B. V. M. Mohan, V. Chaturvedi, R. Mukherjee, K. S. Reddy. (2008) Prevalence and determinants of diabetes mellitus in the Indian industrial population. Diabetic Medicine 25:10, 1187-1194
CrossRef103
Leif Lapidus, Susan W. Andersson, Calle Bengtsson, Cecilia Björkelund, Lena Rossander-Hulthén, Lauren Lissner. (2008) Weight and length at birth and their relationship to diabetes incidence and all-cause mortality—A 32-year follow-up of the population study of women in Gothenburg, Sweden. Primary Care Diabetes 2:3, 127-133
CrossRef104
Kerstin Kempf, Wolfgang Rathmann, Christian Herder. (2008) Impaired glucose regulation and type 2 diabetes in children and adolescents. Diabetes/Metabolism Research and Reviews 24:6, 427-437
CrossRef105
Chittaranjan S. Yajnik, Urmila S. Deshmukh. (2008) Maternal nutrition, intrauterine programming and consequential risks in the offspring. Reviews in Endocrine and Metabolic Disorders 9:3, 203-211
CrossRef106
Gluckman, Peter D., Hanson, Mark A., Cooper, Cyrus, Thornburg, Kent L., . (2008) Effect of In Utero and Early-Life Conditions on Adult Health and Disease. New England Journal of Medicine 359:1, 61-73
Full Text107
Narinder Bansal, Omolola O Ayoola, Islay Gemmell, Avni Vyas, Abir Koudsi, John Oldroyd, Peter E Clayton, J Kennedy Cruickshank. (2008) Effects of early growth on blood pressure of infants of British European and South Asian origin at one year of age: the Manchester childrenʼs growth and vascular health study. Journal of Hypertension 26:3, 412-418
CrossRef108
Cesar G Victora, Linda Adair, Caroline Fall, Pedro C Hallal, Reynaldo Martorell, Linda Richter, Harshpal Singh Sachdev. (2008) Maternal and child undernutrition: consequences for adult health and human capital. The Lancet 371:9609, 340-357
CrossRef109
KC Pike, MA Hanson, KM Godfrey. (2008) Review article: Developmental mismatch: consequences for later cardiorespiratory health. BJOG: An International Journal of Obstetrics & Gynaecology 115:2, 149-157
CrossRef110
Jeff Unger. (2007) Management of Diabetes in Pregnancy, Childhood, and Adolescence. Primary Care: Clinics in Office Practice 34:4, 809-843
CrossRef111
Peter W. Nathanielsz, Lucilla Poston, Paul D. Taylor. (2007) In Utero Exposure to Maternal Obesity and Diabetes: Animal Models That Identify and Characterize Implications for Future Health. Clinics in Perinatology 34:4, 515-526
CrossRef112
Viswanathan Mohan, Revale Jaydip, Raj Deepa. (2007) Type 2 diabetes in Asian Indian youth. Pediatric Diabetes 8:s9, 28-34
CrossRef113
Mandy B. Belfort, Sheryl L. Rifas-Shiman, Janet Rich-Edwards, Ken P. Kleinman, Matthew W. Gillman. (2007) Size at Birth, Infant Growth, and Blood Pressure at Three Years of Age. The Journal of Pediatrics 151:6, 670-674
CrossRef114
Warren WR Lee. (2007) An overview of pediatric obesity. Pediatric Diabetes 8:s9, 76-87
CrossRef115
Jonathan Shaw. (2007) Epidemiology of childhood type 2 diabetes and obesity. Pediatric Diabetes 8:s9, 7-15
CrossRef116
C. S. Yajnik, S. S. Deshpande, A. A. Jackson, H. Refsum, S. Rao, D. J. Fisher, D. S. Bhat, S. S. Naik, K. J. Coyaji, C. V. Joglekar, N. Joshi, H. G. Lubree, V. U. Deshpande, S. S. Rege, C. H. D. Fall. (2007) Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study. Diabetologia 51:1, 29-38
CrossRef117
Penny Gordon-Larsen, Linda S. Adair, Chirayath M. Suchindran. (2007) Maternal Obesity Is Associated With Younger Age at Obesity Onset in U.S. Adolescent Offspring Followed Into Adulthood**. Obesity 15:11, 2790-2796
CrossRef118
Jonathan C.K. Wells. (2007) Flaws in the theory of predictive adaptive responses. Trends in Endocrinology & Metabolism 18:9, 331-337
CrossRef119
P Brambilla, A Pietrobelli. (2007) Abnormal body mass index trajectories in childhood and possible health consequences. International Journal of Obesity 31:11, 1761-1762
CrossRef120
Anoop Misra, Lokesh Khurana, Naval K. Vikram, Ashish Goel, Jasjeet S. Wasir. (2007) Metabolic syndrome in children: current issues and South Asian perspective. Nutrition 23:11-12, 895-910
CrossRef121
S. Robinson. (2007) Metabolic programming during pregnancy: epidemiological studies in humans. Genes & Nutrition 2:1, 31-32
CrossRef122
Andrew C.G. Breeze, Christoph C. Lees. (2007) Prediction and perinatal outcomes of fetal growth restriction. Seminars in Fetal and Neonatal Medicine 12:5, 383-397
CrossRef123
C V Joglekar, C H D Fall, V U Deshpande, N Joshi, A Bhalerao, V Solat, T M Deokar, S D Chougule, S D Leary, C Osmond, C S Yajnik. (2007) Newborn size, infant and childhood growth, and body composition and cardiovascular disease risk factors at the age of 6 years: the Pune Maternal Nutrition Study. International Journal of Obesity 31:10, 1534-1544
CrossRef124
S. Sloan, A. Gildea, M. Stewart, H. Sneddon, D. Iwaniec. (2007) Early weaning is related to weight and rate of weight gain in infancy. Child: Care, Health and Development 0:0, 070922003636004-???
CrossRef125
Sherin U. Devaskar, Manikkavasagar Thamotharan. (2007) Metabolic programming in the pathogenesis of insulin resistance. Reviews in Endocrine and Metabolic Disorders 8:2, 105-113
CrossRef126
Rebecca A. Simmons. (2007) Role of metabolic programming in the pathogenesis of β-cell failure in postnatal life. Reviews in Endocrine and Metabolic Disorders 8:2, 95-104
CrossRef127
Barry Bogin, Maria Inês Varela Silva, Luis Rios. (2007) Life history trade-offs in human growth: Adaptation or pathology?. American Journal of Human Biology 19:5, 631-642
CrossRef128
E Ritz. (2007) Is the renal risk of adults determined in utero?. Kidney International 72:6, 667-668
CrossRef129
C. M. Schooling, C. Jiang, T. H. Lam, G. N. Thomas, M. Heys, Bmbs, X. Lao, W. Zhang, P. Adab, K. K. Cheng, G. M. Leung. (2007) Height, Its Components, and Cardiovascular Risk Among Older Chinese: A Cross-Sectional Analysis of the Guangzhou Biobank Cohort Study. American Journal of Public Health 97:10, 1834-1841
CrossRef130
Palany Raghupathy, Belavendra Antonisamy, Caroline H.D. Fall, Finney S. Geethanjali, Samantha D. Leary, Julia Saperia, G. Priya, Abel Rajaratnam, Joseph Richard. (2007) High prevalence of glucose intolerance even among young adults in south India. Diabetes Research and Clinical Practice 77:2, 269-279
CrossRef131
Syed Shah, Muhammad Iqbal, Jocelyne Karam, Moro Salifu, Samy I. McFarlane. (2007) Oxidative Stress, Glucose Metabolism, and the Prevention of Type 2 Diabetes: Pathophysiological Insights. Antioxidants & Redox Signaling 9:7, 911-929
CrossRef132
Yingkui Yang, Min Chen, Tara J. Loux, Carroll M. Harmon. (2007) Regulation of FAT/CD36 mRNA gene expression by long chain fatty acids in the differentiated 3T3-L1 cells. Pediatric Surgery International 23:7, 675-683
CrossRef133
James F. Clapp III, Beth Lopez. (2007) Size at Birth, Obesity and Blood Pressure at Age Five. Metabolic Syndrome and Related Disorders 5:2, 116-126
CrossRef134
Peter W. Nathanielsz, Lucilla Poston, Paul D. Taylor. (2007) In Utero Exposure to Maternal Obesity and Diabetes: Animal Models That Identify and Characterize Implications for Future Health. Obstetrics and Gynecology Clinics of North America 34:2, 201-212
CrossRef135
KEITH M. GODFREY, KAREN A. LILLYCROP, GRAHAM C. BURDGE, PETER D. GLUCKMAN, MARK A. HANSON. (2007) Epigenetic Mechanisms and the Mismatch Concept of the Developmental Origins of Health and Disease. Pediatric Research 61:Supplement, 5R-10R
CrossRef136
Chiaki Tanaka, Shigeho Tanaka, Junko Kawahara, Taishi Midorikawa. (2007) Triaxial Accelerometry for Assessment of Physical Activity in Young Children*. Obesity 15:5, 1233-1241
CrossRef137
J. G. Eriksson. (2007) Epidemiology, genes and the environment: lessons learned from the Helsinki Birth Cohort Study. Journal of Internal Medicine 261:5, 418-425
CrossRef138
Mervyn Deitel, Khaled Gawdat, John Melissas. (2007) Reporting Weight Loss 2007. Obesity Surgery 17:5, 565-568
CrossRef139
Garth L. Nicolson. (2007) Metabolic syndrome and mitochondrial function: Molecular replacement and antioxidant supplements to prevent membrane peroxidation and restore mitochondrial function. Journal of Cellular Biochemistry 100:6, 1352-1369
CrossRef140
Karri Silventoinen, Meike Bartels, Daniëlle Posthuma, G. Frederiek Estourgie-van Burk, Gonneke Willemsen, Toos C. E. M van Beijsterveldt, Dorret I Boomsma. (2007) Genetic Regulation of Growth in Height and Weight from 3 to 12 Years of Age: A Longitudinal Study of Dutch Twin Children. Twin Research and Human Genetics 10:2, 354-363
CrossRef141
Keng Ee Choo, Kim Bee Lau, Wendy A. Davis, Peng Hong Chew, Alicia J. Jenkins, Timothy M.E. Davis. (2007) Cardiovascular risk factors in pre-pubertal Malays: Effects of diabetic parentage. Diabetes Research and Clinical Practice 76:1, 119-125
CrossRef142
Subhashini Yaturu, Sushil Jain. 2007. Obesity and Type 2 Diabetes. , 139-154.
CrossRef143
MATTHEW W. GILLMAN, DAVID BARKER, DENNIS BIER, FELINO CAGAMPANG, JOHN CHALLIS, CAROLINE FALL, KEITH GODFREY, PETER GLUCKMAN, MARK HANSON, DIANA KUH, PETER NATHANIELSZ, PENELOPE NESTEL, KENT L. THORNBURG. (2007) Meeting Report on the 3rd International Congress on Developmental Origins of Health and Disease (DOHaD). Pediatric Research PAP,
CrossRef144
D. J. P. Barker. (2007) Obesity and early life. Obesity Reviews 8:s1, 45-49
CrossRef145
Yuki ABE, Toru KIKUCHI, Keisuke NAGASAKI, Makoto HIURA, Yukie TANAKA, Yohei OGAWA, Makoto UCHIYAMA. (2007) Lower Birth Weight Associated with Current Overweight Status Is Related with the Metabolic Syndrome in Obese Japanese Children. Hypertension Research 30:7, 627-634
CrossRef146
I E Buchan, P E Bundred, D J Kitchiner, T J Cole. (2007) Body mass index has risen more steeply in tall than in short 3-year olds: serial cross-sectional surveys 1988–2003. International Journal of Obesity 31:1, 23-29
CrossRef147
Peter D. Gluckman, Alan S. Beedle, Mark A. Hanson, Mark H. Vickers. (2007) Leptin Reversal of the Metabolic Phenotype: Evidence for the Role of Developmental Plasticity in the Development of the Metabolic Syndrome. Hormone Research 67:1, 115-120
CrossRef148
Peter D. Gluckman, Mark A. Hanson, Alan S. Beedle. (2007) Early life events and their consequences for later disease: A life history and evolutionary perspective. American Journal of Human Biology 19:1, 1-19
CrossRef149
J G Eriksson. (2006) Early growth, and coronary heart disease and type 2 diabetes: experiences from the Helsinki Birth Cohort Studies. International Journal of Obesity 30, S18-S22
CrossRef150
M F Rolland-Cachera, M Deheeger, M Maillot, F Bellisle. (2006) Early adiposity rebound: causes and consequences for obesity in children and adults. International Journal of Obesity 30, S11-S17
CrossRef151
A G Dulloo, J Jacquet, J Seydoux, J-P Montani. (2006) The thrifty ‘catch-up fat’ phenotype: its impact on insulin sensitivity during growth trajectories to obesity and metabolic syndrome. International Journal of Obesity 30, S23-S35
CrossRef152
SAROJ SAIGAL, BARBARA STOSKOPF, DAVID STREINER, NIGEL PANETH, JANET PINELLI, MICHAEL BOYLE. (2006) Growth Trajectories of Extremely Low Birth Weight Infants From Birth to Young Adulthood: A Longitudinal, Population-Based Study. Pediatric Research 60:6, 751-758
CrossRef153
K Andreasyan, A-L Ponsonby, T Dwyer, R Morley, M Riley, K Dear, J Cochrane. (2006) Higher maternal dietary protein intake in late pregnancy is associated with a lower infant ponderal index at birth. European Journal of Clinical Nutrition
CrossRef154
J. G. Eriksson, C. Osmond, E. Kajantie, T. J. Forsén, D. J. P. Barker. (2006) Patterns of growth among children who later develop type 2 diabetes or its risk factors. Diabetologia 49:12, 2853-2858
CrossRef155
J. C. Jimenez-Chillaron, M. Hernandez-Valencia, A. Lightner, R. R. Faucette, C. Reamer, R. Przybyla, S. Ruest, K. Barry, J. P. Otis, M. E. Patti. (2006) Reductions in caloric intake and early postnatal growth prevent glucose intolerance and obesity associated with low birthweight. Diabetologia 49:8, 1974-1984
CrossRef156
Selma Feldman Witchel. (2006) Puberty and polycystic ovary syndrome. Molecular and Cellular Endocrinology 254-255, 146-153
CrossRef157
Tazeen H Jafar. (2006) Hypertension and kidney disease in Asia. Current Opinion in Nephrology and Hypertension 15:3, 291-295
CrossRef158
Jafar, Tazeen H., . (2006) The Growing Burden of Chronic Kidney Disease in Pakistan. New England Journal of Medicine 354:10, 995-997
Full Text159
Rebecca A. Simmons. (2006) Developmental origins of diabetes: The role of oxidative stress. Free Radical Biology and Medicine 40:6, 917-922
CrossRef160
M. J. J. Finken, M. G. Keijzer-Veen, F. W. Dekker, M. Frölich, E. T. M. Hille, J. A. Romijn, J. M. Wit, . (2006) Preterm birth and later insulin resistance: effects of birth weight and postnatal growth in a population based longitudinal study from birth into adult life. Diabetologia 49:3, 478-485
CrossRef161
M Jeffreys, D A Lawlor, B Galobardes, P McCarron, S Kinra, S Ebrahim, G Davey Smith. (2006) Lifecourse weight patterns and adult-onset diabetes: the Glasgow Alumni and British Women's Heart and Health studies. International Journal of Obesity 30:3, 507-512
CrossRef162
Vincent W. V. Jaddoe, Jacqueline C. M. Witteman. (2006) Hypotheses on the Fetal Origins of Adult Diseases: Contributions of Epidemiological Studies. European Journal of Epidemiology 21:2, 91-102
CrossRef163
S. A. Phipps, P. S. Burton, L. S. Osberg, L. N. Lethbridge. (2006) Poverty and the extent of child obesity in Canada, Norway and the United States. Obesity Reviews 7:1, 5-12
CrossRef164
Marlene Schwartz, Ingrid Kohlstadt, Arline Salbe. 2006. Childhood Obesity. , 253-269.
CrossRef165
(2006) Childhood Growth and Coronary Events. New England Journal of Medicine 354:3, 303-304
Full Text166
Archana Dayal Arya. (2006) Small for gestation and growth hormone therapy. The Indian Journal of Pediatrics 73:1, 73-78
CrossRef167
Zulfiqar A. Bhutta. (2006) The Million Death Study in India: Can It Help in Monitoring the Millennium Development Goals?. PLoS Medicine 3:2, e103
CrossRef168
Made K. Ramadhani, Diederick E. Grobbee, Michiel L. Bots, Manuel Castro Cabezas, Lydia E. Vos, Anath Oren, Cuno S.P.M. Uiterwaal. (2006) Lower birth weight predicts metabolic syndrome in young adults: The Atherosclerosis Risk in Young Adults (ARYA)-study. Atherosclerosis 184:1, 21-27
CrossRef169
George A. Bray. 2006. Obesity Is a Major Health Problem: Causes and Natural History. , 1-20.
CrossRef170
V. Mericq. (2006) Prematurity and Insulin Sensitivity. Hormone Research 65:3, 131-136
CrossRef171
L. E. Vos, A. Oren, M. L. Bots, W. H. M. Gorissen, D. E. Grobbee, C. S. P. M. Uiterwaal. (2006) Birth Size and Coronary Heart Disease Risk Score in Young Adulthood. The Atherosclerosis Risk in Young Adults (ARYA) Study. European Journal of Epidemiology 21:1, 33-38
CrossRef172
K.K. Ong. (2006) Size at Birth, Postnatal Growth and Risk of Obesity. Hormone Research 65:3, 65-69
CrossRef173
M. Wadsworth, S. Butterworth, M. Marmot, R. Ecob, R. Hardy. (2005) Early growth and type 2 diabetes: evidence from the 1946 British birth cohort. Diabetologia 48:12, 2505-2510
CrossRef174
Stephen Daniels. 2005. Critical Periods for Abnormal Weight Gain in Children and Adolescents. , 67-78.
CrossRef175
Alison Field. 2005. Epidemiology of the Health and Economic Consequences of Pediatric Obesity. , 1-18.
CrossRef176
Shumei Sun. 2005. Growth and Development. , 19-33.
CrossRef177
K Srinath Reddy, Bela Shah, Cherian Varghese, Anbumani Ramadoss. (2005) Responding to the threat of chronic diseases in India. The Lancet 366:9498, 1744-1749
CrossRef178
Rachael W Taylor, Andrea M Grant, Ailsa Goulding, Sheila M Williams. (2005) Early adiposity rebound: review of papers linking this to subsequent obesity in children and adults. Current Opinion in Clinical Nutrition and Metabolic Care 8:6, 607-612
CrossRef179
Barker, David J.P., Osmond, Clive, Forsén, Tom J., Kajantie, Eero, Eriksson, Johan G., . (2005) Trajectories of Growth among Children Who Have Coronary Events as Adults. New England Journal of Medicine 353:17, 1802-1809
Full Text180
Gillman, Matthew W., . (2005) Developmental Origins of Health and Disease. New England Journal of Medicine 353:17, 1848-1850
Full Text181
Rebecca Simmons. (2005) Developmental origins of adult metabolic disease: concepts and controversies. Trends in Endocrinology & Metabolism 16:8, 390-394
CrossRef182
Lawrence Hammer, Rebecka Peebles. 2005. Childhood Obesity. .
CrossRef183
Richard Gross, Xianlin Han. 2005. Specific Lipid Alterations in Alzheimer’s Disease and Diabetes. , 285-306.
CrossRef184
Irene Elgen, Kjell A. Johansson, Trond Markestad, Kristian Sommerfelt. (2005) A non-handicapped cohort of low-birthweight children: Growth and general health status at 11 years of age. Acta Paediatrica 94:9, 1203-1207
CrossRef185
Francine Ratner Kaufman. (2005) Type 2 Diabetes in Children and Youth. Endocrinology & Metabolism Clinics of North America 34:3, 659-676
CrossRef186
David B. Dunger, Ken K. Ong. (2005) Endocrine and Metabolic Consequences of Intrauterine Growth Retardation. Endocrinology & Metabolism Clinics of North America 34:3, 597-615
CrossRef187
NADIA EZZAHIR, CORINNE ALBERTI, SAMIA DEGHMOUN, ISABELLE ZACCARIA, PAUL CZERNICHOW, CLAIRE L??VY-MARCHAL, DELPHINE JAQUET. (2005) Time Course of Catch-up in Adiposity Influences Adult Anthropometry in Individuals Who Were Born Small for Gestational Age. Pediatric Research 58:2, 243-247
CrossRef188
D. A. Lawlor, C. J. Riddoch, A. S. Page, S. A. Anderssen, K. Froberg, M. Harro, D. Stansbie, G. Davey Smith. (2005) The association of birthweight and contemporary size with insulin resistance among children from Estonia and Denmark: findings from the European Youth Heart Study. Diabetic Medicine 22:7, 921-930
CrossRef189
Johan G. Eriksson. (2005) Early growth and adult health outcomes - lessons learned from the Helsinki Birth Cohort Study. Maternal and Child Nutrition 1:3, 149-154
CrossRef190
Catherine Law. (2005) Early growth and chronic disease: a public health overview. Maternal and Child Nutrition 1:3, 169-176
CrossRef191
Aryeh D. Stein, Angela M. Thompson, Ashley Waters. (2005) Childhood growth and chronic disease: evidence from countries undergoing the nutrition transition. Maternal and Child Nutrition 1:3, 177-184
CrossRef192
N. S. Levitt, E. V. Lambert, D. Woods, J. R. Seckl, C. N. Hales. (2005) Adult BMI and fat distribution but not height amplify the effect of low birthweight on insulin resistance and increased blood pressure in 20-year-old South Africans. Diabetologia 48:6, 1118-1125
CrossRef193
D. Jaquet, S. Deghmoun, D. Chevenne, D. Collin, P. Czernichow, C. Lévy-Marchal. (2005) Dynamic change in adiposity from fetal to postnatal life is involved in the metabolic syndrome associated with reduced fetal growth. Diabetologia 48:5, 849-855
CrossRef194
George A. Bray, Catherine M. Champagne. (2005) Beyond Energy Balance: There Is More to Obesity than Kilocalories. Journal of the American Dietetic Association 105:5, 17-23
CrossRef195
Stuart R Dalziel, Natalie K Walker, Varsha Parag, Colin Mantell, Harold H Rea, Anthony Rodgers, Jane E Harding. (2005) Cardiovascular risk factors after antenatal exposure to betamethasone: 30-year follow-up of a randomised controlled trial. The Lancet 365:9474, 1856-1862
CrossRef196
John Lynch, George Davey Smith. (2005) A LIFE COURSE APPROACH TO CHRONIC DISEASE EPIDEMIOLOGY. Annual Review of Public Health 26:1, 1-35
CrossRef197
V. W. V. Jaddoe, L. Ay, H. A. Büller, A. Hofman, A. C. S. Hokken-Koelega, M. Osch-Gevers, R. J. M. Snijders, E. A. P. Steegers, B. O. Verburg, J. C. M. Witteman. (2005) Vroege oorzaken van hart- en vaatziekten, type−2-diabetes en obesitas. Tijdschrift voor kindergeneeskunde 73:2, 187-191
CrossRef198
Peter D. Gluckman, Wayne Cutfield, Paul Hofman, Mark A. Hanson. (2005) The fetal, neonatal, and infant environments—the long-term consequences for disease risk. Early Human Development 81:1, 51-59
CrossRef199
Yukie TANAKA, Toru KIKUCHI, Keisuke NAGASAKI, Makoto HIURA, Yohei OGAWA, Makoto UCHIYAMA. (2005) Lower Birth Weight and Visceral Fat Accumulation Are Related to Hyperinsulinemia and Insulin Resistance in Obese Japanese Children. Hypertension Research 28:6, 529-536
CrossRef200
Xavier Formiguera, Ana Cantón. (2004) Obesity: epidemiology and clinical aspects. Best Practice & Research Clinical Gastroenterology 18:6, 1125-1146
CrossRef201
DJP Barker. (2004) The developmental origins of chronic adult disease. Acta Paediatrica 93, 26-33
CrossRef202
R. Singh, J. Shaw, P. Zimmet. (2004) Epidemiology of childhood type 2 diabetes in the developing world. Pediatric Diabetes 5:3, 154-168
CrossRef203
(2004) The Changing Face and Implications of Childhood Obesity. New England Journal of Medicine 350:23, 2414-2416
Full Text204
Dietz, William H., . (2004) Overweight in Childhood and Adolescence. New England Journal of Medicine 350:9, 855-857
Full Text205
Michael G. Sargent. (1996) Surviving childhood in India and Ethiopia. Interdisciplinary Science Reviews 21:1, 11-26
CrossRef
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