Original Article
Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer
N Engl J Med 2004; 350:1945-1952May 6, 2004
- Abstract
Background
We compared concomitant cisplatin and irradiation with radiotherapy alone as adjuvant treatment for stage III or IV head and neck cancer.
Methods
After undergoing surgery with curative intent, 167 patients were randomly assigned to receive radiotherapy alone (66 Gy over a period of 6 1/2 weeks) and 167 to receive the same radiotherapy regimen combined with 100 mg of cisplatin per square meter of body-surface area on days 1, 22, and 43 of the radiotherapy regimen.
Results
After a median follow-up of 60 months, the rate of progression-free survival was significantly higher in the combined-therapy group than in the group given radiotherapy alone (P=0.04 by the log-rank test; hazard ratio for disease progression, 0.75; 95 percent confidence interval, 0.56 to 0.99), with 5-year Kaplan–Meier estimates of progression-free survival of 47 percent and 36 percent, respectively. The overall survival rate was also significantly higher in the combined-therapy group than in the radiotherapy group (P=0.02 by the log-rank test; hazard ratio for death, 0.70; 95 percent confidence interval, 0.52 to 0.95), with five-year Kaplan–Meier estimates of overall survival of 53 percent and 40 percent, respectively. The cumulative incidence of local or regional relapses was significantly lower in the combined-therapy group (P=0.007). The estimated five-year cumulative incidence of local or regional relapses (considering death from other causes as a competing risk) was 31 percent after radiotherapy and 18 percent after combined therapy. Severe (grade 3 or higher) adverse effects were more frequent after combined therapy (41 percent) than after radiotherapy (21 percent, P=0.001); the types of severe mucosal adverse effects were similar in the two groups, as was the incidence of late adverse effects.
Conclusions
Postoperative concurrent administration of high-dose cisplatin with radiotherapy is more efficacious than radiotherapy alone in patients with locally advanced head and neck cancer and does not cause an undue number of late complications.
Media in This Article
Figure 1
Kaplan–Meier Estimates of Progression-free Survival.Figure 2
Kaplan–Meier Estimates of Overall Survival.Article Activity
- Article
Local or regional recurrences and distant metastases are frequent after surgical treatment of stage III or IV squamous-cell carcinoma of the head and neck. The risk of failure is particularly high in patients with inadequate resection margins, extranodal spread, or multiple involved lymph nodes.1-4 In patients with such locally advanced tumors, surgery is usually followed by adjuvant radiotherapy. The advantage of postoperative radiotherapy is well documented2-5 and compares favorably with the benefit afforded by preoperative irradiation.6,7
Several studies have demonstrated that concurrent treatment with radiotherapy and chemotherapy is a promising approach for locally advanced squamous-cell carcinoma that is not amenable to surgery,8,9 justifying tests of the efficacy of chemotherapy plus radiotherapy as postoperative (adjuvant) treatment.10 Indeed, sequential adjuvant treatment with chemotherapy and radiotherapy significantly reduced the probability of nodal failure and distant metastasis, and this improvement was directly linked to the levels of clinical and pathological risk.11 Moreover, in early randomized trials, concomitant postoperative radiotherapy and chemotherapy significantly improved local or regional control but had no effect on overall survival.12,13
In 1994, the European Organization for Research and Treatment of Cancer (EORTC) began a randomized trial (EORTC trial 22931) to test the hypothesis that adjuvant chemotherapy and radiotherapy improves progression-free survival, overall survival, and local or regional control more than does radiotherapy alone in patients with stage III or IV head and neck cancer.
Methods
Patient Population and Eligibility Criteria
The main objective of this study was to determine whether the addition of cisplatin to high-dose radiotherapy after radical surgery increases progression-free survival in patients at high risk for recurrent cancer. Secondary end points included overall survival, relapse, and acute and late adverse effects.
In this multicenter study, the stage of the tumor was determined on the basis of the histologic findings and classified according to the criteria of the Union Internationale contre le Cancer.14 All patients underwent a full endoscopic examination during which a diagram was made of the extent of disease. Chest radiography, serum chemical analyses, and a complete blood count were obtained. Computed tomography of the site of the primary tumor and the neck was highly recommended.
To be eligible, patients had to have previously untreated, histologically proven squamous-cell carcinoma arising from the oral cavity, oropharynx, hypopharynx, or larynx, with a tumor (T) stage of pT3 or pT4 and any nodal stage (N), except T3N0 of the larynx, with negative resection margins, or a tumor stage of 1 or 2 with a nodal stage of 2 or 3 and no distant metastasis (M0). Patients with stage T1 or T2 and N0 or N1 who had unfavorable pathological findings (extranodal spread, positive resection margins, perineural involvement, or vascular tumor embolism) were also eligible, as were those with oral-cavity or oropharyngeal tumors with involved lymph nodes at level IV or V, according to the anatomical lymph-node distribution proposed by Robbins et al.15
Patients had to be at least 18 years of age and no older than 70 years, with a performance status of 0, 1, or 2, according to the scale of the World Health Organization; they also had to have a serum creatinine concentration of 1.36 mg per deciliter (120 μmol per liter) or less, a white-cell count of at least 4000 per cubic millimeter, a platelet count of at least 100,000 per cubic millimeter, and a hemoglobin concentration of at least 11.0 g per deciliter (6.8 mmol per liter). Aminotransferase values and bilirubin values could not exceed twice the upper limit of normal. Patients who had a history of invasive or synchronous cancer (except nonmelanoma skin cancer), had previously received chemotherapy, or had known central nervous system disease were excluded from the study.
The study protocol was accepted by the independent review committee of each participating center. Informed consent was obtained from all patients in accordance with institutional guidelines.
Surgery
All eligible patients underwent primary surgery performed with curative intent. The extent of surgical resection of the primary tumor and neck-dissection procedures followed accepted criteria for adequate excision, which depend on the volume and location of the tumor. If the tumor was within 5 mm of the surgical margins, the resection margins were considered to be close.
Radiotherapy
All patients received postoperative radiotherapy consisting of conventionally fractionated doses of 2 Gy each in five weekly sessions. Maximal and minimal target-volume doses and the maximal dose to the spinal cord were recorded. Treatments were conducted on linear accelerators of 4 to 6 MV with the use of isocentric techniques. A large volume encompassing the primary site and all draining lymph nodes at risk received a dose of up to 54 Gy in 27 fractions over a period of 5 1/2 weeks. Regions that were at high risk for malignant dissemination or that had inadequate resection margins received a 12-Gy boost (total, 66 Gy) in 33 fractions over a period of 6 1/2 weeks. The dose to the spinal cord was limited to 45 Gy.
Chemotherapy
Chemotherapy consisted of 100 mg of cisplatin per square meter of body-surface area on days 1, 22, and 43 of the course of radiotherapy. Patients received prophylactic hydration and antiemetic agents.
Follow-up
Patients were evaluated every 2 months for the first 6 months, every 4 months for the next 24 months, every 6 months for the next 2 years, and annually thereafter. Adverse effects, weight, performance status, and tumor response were assessed at baseline, weekly for the first eight weeks, and at each follow-up assessment.
Study Design
After surgery, patients were randomly assigned to receive radiotherapy alone or radiotherapy combined with chemotherapy. Randomization was centralized, either electronically (by means of the Internet) or by telephone, by the EORTC Data Center. Principal eligibility criteria were checked at the time of randomization. The Pocock minimization technique was used for the randomization; center and tumor site were used as stratification factors.
The trial was designed to detect an absolute increase in progression-free survival of 15 percent (from 40 percent to 55 percent at three years) with a two-sided 5 percent significance level and a statistical power of 80 percent. We planned to recruit 338 patients. Recruitment was stopped as soon as the 178th event occurred, before the final analysis. Although not initially planned, an interim analysis was performed at the end of the recruitment period and interim results were published.16 The final analysis included 26 additional months of follow-up. According to the intention-to-treat principle, no patient was excluded from the demographic and efficacy analysis. Progression-free survival, the primary end point, was defined as the time from randomization to any type of progression or death from any cause. Overall survival was defined as the time from randomization to death from any cause. Both end points were estimated by means of Kaplan–Meier methods, and comparisons between treatment groups used the log-rank test.17 The cumulative incidences of local or regional relapses, late reactions, metastases, and second primary tumors were analyzed as secondary end points. The cumulative incidence of each individual event was estimated by the competing-risk method, in which death from other causes was considered a competing risk. Comparisons between treatment groups used Gray's test.18 All tests were two-sided. Version 2.0 of the Common Toxicity Criteria of the Radiation Therapy Oncology Group was used to grade adverse effects. Likewise, the Late Radiation Morbidity Scoring Scheme of the Radiation Therapy Oncology Group and the EORTC was used to assess late adverse effects.
Results
Characteristics of the Patients
From February 1994 to October 2000, 334 patients from 23 institutions consented to participate in the trial; 92 percent were men, and 69 percent were more than 50 years of age. Of these 334 patients, 167 were randomly assigned to receive radiotherapy alone and 167 to receive concurrent chemotherapy and radiotherapy. The baseline characteristics of the two groups were similar (Table 1Table 1
Characteristics of Patients and Tumors.). The median and maximal follow-up times were 60 months and 100 months, respectively (58 and 96, respectively, in the radiotherapy group, and 61 and 100, respectively, in the combined-therapy group).Treatment
Thirty-two percent of patients in the combined-therapy group started radiotherapy more than 43 days after the surgical procedure, as compared with 25 percent of those in the radiotherapy group. A total of 21 patients (12 in the radiotherapy group and 9 in the combined-therapy group) started treatment 8 to 10 weeks after surgery. A total of 11 patients never started the radiotherapy protocol (2 in the radiotherapy group and 9 in the combined-therapy group). In addition, 15 patients (4 percent: 7 patients in the radiotherapy group and 8 in the combined-therapy group) received less than 60 Gy, which corresponds to a 10 percent deviation from the total value of 66 Gy listed in the protocol. Among patients who received at least 60 Gy, 81 had treatment interruptions resulting in a total duration of treatment of more than seven weeks (42 in the radiotherapy group and 39 in the combined-therapy group).
The median and the interquartile range of the total dose of radiation were the same in both groups: 66 Gy (interquartile range, 65 to 66). The median duration of treatment was 47 days (interquartile range, 45 to 51) in the radiotherapy group and 47 days (interquartile range, 44 to 50.5) in the combined-therapy group.
In the combined-therapy group, 17 patients (10 percent) never started chemotherapy, whereas 18 patients (11 percent) stopped chemotherapy after one course and 25 patients (15 percent) stopped chemotherapy after two courses. Compliance with chemotherapy also decreased with the number of courses delivered: the first, second, and third cycles were administered on time and without delay in 147 patients (88 percent), 110 patients (66 percent), and 82 patients (49 percent), respectively.
Severe Acute Adverse Effects
Although the cumulative incidence of severe (grade 3 or higher) functional mucosal adverse effects was significantly greater in the combined-therapy group than in the radiation group (incidence, 41 percent vs. 21 percent; P=0.001), the types of mucosal reactions were similar in the two groups (P=0.28). The incidence of muscular fibrosis of grade 3 or higher was greater in the combined-therapy group than in the radiotherapy group (10 percent vs. 5 percent), whereas the incidence of severe xerostomia was lower (14 percent vs. 20 percent). Other severe complications in the radiotherapy and combined-therapy groups were as follows: dysphagia (12 percent and 10 percent, respectively), shoulder syndrome (8 percent and 5 percent, respectively), impaired lymphatic drainage (7 percent and 2 percent, respectively), laryngeal complications (1 percent and 2 percent, respectively), bone complications (1 percent and 2 percent, respectively), mucosal necrosis (1 percent and 2 percent, respectively), and skin and connective-tissue fibrosis (1 percent and 2 percent, respectively).
Severe leukopenia occurred in 16 percent of the patients in the combined-therapy group, and severe granulocytopenia occurred in 13 percent. Severe nausea occurred in 12 percent of the patients receiving concurrent chemotherapy and radiotherapy, and severe vomiting occurred in 11 percent. These were the only severe chemotherapy-related adverse effects reported in at least 10 percent of the patients in this group. The quality of life was not assessed in this study.
Progression-Free Survival
Progression-free survival was the primary end point of this trial. After a median follow-up of 60 months, a total of 194 treatment failures (103 in the radiotherapy group and 91 in the combined-therapy group) had been recorded. There was a significant (P=0.04 by the log-rank test) difference in progression-free survival in favor of the combined-therapy group over the radiotherapy group (Figure 1Figure 1
Kaplan–Meier Estimates of Progression-free Survival.) (hazard ratio for disease progression, 0.75; 95 percent confidence interval, 0.56 to 0.99). The estimated median duration of progression-free survival was 23 months (95 percent confidence interval, 18 to 30) in the radiotherapy group and 55 months (95 percent confidence interval, 33 to 75) in the combined-therapy group, and the Kaplan–Meier estimates of 5-year progression-free survival were 36 percent and 47 percent, respectively. The disease progressed in 159 patients (90 in the radiotherapy group and 69 in the combined-therapy group), and 35 died without reported evidence of disease (13 in the radiotherapy group and 22 in the combined-therapy group).Overall Survival
A total of 174 patients (52 percent) died. There was a significant (P=0.02 by the log-rank test) difference in overall survival in favor of the combined-therapy group over the radiotherapy group (Figure 2Figure 2
Kaplan–Meier Estimates of Overall Survival.) (hazard ratio for death, 0.70; 95 percent confidence interval, 0.52 to 0.95). The estimated median time to death was 32 months (95 percent confidence interval, 25 to 46) in the radiotherapy group and 72 months (95 percent confidence interval, 51 to 94) in the combined-therapy group. The Kaplan–Meier estimates of overall survival at five years were 40 percent in the radiotherapy group and 53 percent in the combined-therapy group. Head and neck cancer was the cause of death in 116 patients — 71 (43 percent) in the radiotherapy group and 45 (27 percent) in the combined-therapy group. Treatment-related adverse effects were the cause of death in one patient in each group. Two patients in the radiotherapy group died of infection.Cumulative Incidence of Local and Regional Relapses
There were 83 local or regional failures (52 in the radiotherapy group and 31 in the combined-therapy group). The estimated five-year cumulative incidence of local or regional relapses was 31 percent in the radiotherapy group and 18 percent in the combined-therapy group (Figure 3Figure 3
Cumulative Incidence of Local or Regional Relapses.). The difference was significant (P=0.007 by Gray's test).Cumulative Incidence of Metastases and Second Primary Tumors
The estimated five-year cumulative incidence of metastases was 25 percent in the radiotherapy group and 21 percent in the combined-therapy group. The difference was not significant (P=0.61 by Gray's test). The estimated five-year cumulative incidence of second primary tumors was 13 percent in the radiotherapy group and 12 percent in the combined-therapy group; the difference was not significant (P=0.83 by Gray's test).
Cumulative Incidence of Late Complications
The cumulative incidence of late complications was not significantly different between the two groups (Figure 4Figure 4
Cumulative Incidence of Late Adverse Effects of at Least Grade 3.). As was the case with acute functional reactions, the incidence of severe muscular fibrosis was higher in the combined-therapy group than in the radiotherapy group (10 percent vs. 5 percent), but the incidence of severe xerostomia was lower (14 percent vs. 22 percent).Discussion
Various strategies have been proposed to improve the outcome among patients who have resectable, locally advanced squamous-cell carcinoma of the head and neck with a high risk for recurrence or metastasis. In 1970, Fletcher and Evers reported the first convincing evidence of the benefit of combining radiotherapy with surgery.5 Since then, the risk of treatment failure above the clavicles has been repeatedly found to be significantly reduced by the use of postoperative radiotherapy,3,4,19 and it has been clearly demonstrated that patients at high risk for recurrent disease or metastasis should be treated aggressively after surgery.20
From the late 1970s to the early 1990s, promising results emerged from the use of various combinations of postoperative chemotherapy and radiotherapy in randomized10,21,22 and nonrandomized23-25 studies. Among the former, Intergroup Study 00-34 showed that the sequential addition of cisplatin and fluorouracil to radiotherapy reduced the incidence of nodal and distant failures, but did not improve survival.10
Cisplatin has been investigated in the management of squamous-cell carcinomas of the head and neck since the early 1970s. The interest in this compound was due to its presumed radiosensitizing role, whether given in small weekly doses or in higher doses (100 mg per square meter) every three weeks (days 1, 22, and 43 during radiotherapy).26 We used the latter approach, but when our trial began in 1994, most trials of adjuvant treatment had not demonstrated the superiority of combined therapy over radiotherapy alone in patients with locally advanced carcinoma of the head and neck.
We found that concurrent chemotherapy and radiotherapy significantly increased progression-free survival. The five-year actuarial estimates of progression-free survival were 47 percent in the combined-therapy group and 36 percent in the radiotherapy group, and the respective values for overall survival were 53 percent and 40 percent. These differences are in line with those reported in other trials and meta-analyses, showing that locally advanced tumors respond better to concurrent chemotherapy and radiotherapy than to radiotherapy alone.27-33
Apart from a significant effect on survival indexes, adjuvant chemotherapy and radiotherapy were also associated with a pattern of failure that differed from that associated with radiotherapy. The estimated five-year rate of death from head and neck cancer was reduced from 43 percent to 27 percent by the concomitant addition of cisplatin to radiotherapy. Combined therapy did not, however, reduce the probability of distant relapse. Two thirds of the patients received at least two full cycles of chemotherapy, and 49 percent received the planned three courses without any delay or dose reduction. Notwithstanding the more aggressive treatment in the combined-therapy group, the incidence of acute adverse effects after cisplatin and radiotherapy was acceptable, and the incidence of severe late adverse effects was similar in the two groups (Figure 4).
The interim analysis,16 performed after a median follow-up of 34 months, demonstrated a significant advantage of combined therapy over radiotherapy alone, according to an O'Brien–Fleming sequential design, with respect to both progression-free survival (143 events; P=0.0096; estimated hazard ratio, 0.56) and overall survival (115 events; P=0.0057; estimated hazard ratio, 0.65). The shape of the progression-free survival curve (Figure 1) suggests that the effect of chemotherapy decreases over time (the hazard is nonproportional).
Our results must be interpreted in the light of various factors that can influence the magnitude of the effect of combined chemotherapy and radiotherapy, as demonstrated by the results of the Radiation Therapy Oncology Group 95-01 trial.34 In that trial, primary tumor sites were evenly distributed among the oral cavity, larynx, hypopharynx, and oropharynx, although there were slightly more oropharyngeal cancers. The design of our study did not include a subgroup analysis on this basis. Thus, the extent of benefit from combined chemotherapy and radiotherapy at particular sites cannot be reliably assessed. Likewise, the selection of patients in our study was based on both pathological factors (resection-margin status and the presence or absence of extranodal spread, perineural involvement, and vascular embolisms) and clinical factors (tumor and nodal volume and nodal site). Therefore, the participants can be considered at high risk for both local or regional failure and distant metastasis. It is important to note that resection margins were positive in about 30 percent of our patients, with no significant imbalance in this variable between the two groups. It seems unwise to extrapolate the magnitude of the effect we observed to studies based on pathological risk criteria alone.
In conclusion, after surgery with curative intent, adjuvant treatment with high-dose cisplatin plus radiotherapy is more efficacious than radiotherapy alone in patients with squamous-cell carcinoma of the head and neck with unfavorable clinical or pathological factors or both. The addition of chemotherapy to radiotherapy significantly increased the rates of local control, disease-specific survival, and overall survival, without a high incidence of late adverse effects. The effect of the postoperative administration of concurrent chemotherapy and radiotherapy on outcome is likely to be influenced by the criteria used to select patients.
Supported by grants (5U10 CA11488 through 5U10 CA11488-33) from the National Cancer Institute, Bethesda, Md.
The contents of this article are solely the responsibility of the authors and do not necessarily represent the official views of the National Cancer Institute.
We are indebted to Antoine Briffaux (EORTC Data Center) for his help with data management, to the members of the various EORTC staffs for providing outstanding biostatistical and data management throughout the study, to the centers that provided medical and data management, and in particular, to the following contributors: Morbize Julieron, François Eschwege, Pierre Wibault, Institut Gustave Roussy, Villejuif, France; Valérie Moncho-Bernier, Centre Oscar Lambret, Lille, France; Cesare Grandi, Santa Chiara Hospital, Trento, Italy; Hien Nguyen, Department of Radio-Oncology, Free University, Brussels; Renata Soumarova, Research Institute Oncology, Brno, Czech Republic; Christian Glanzmann, Department of Radio-Oncology, Universitätspital, Zurich, Switzerland; Stefan Roth, Heinrich-Heine Universitätsklinik, Düsseldorf, Germany; Boris Jancar, Institute of Oncology, Ljubljana, Slovenia; Elizabeth Junor, Western Infirmary, Glasgow, United Kingdom; Frédéric Dhermain, Centre Henri Becquerel, Rouen, France; David Morgan, Nottingham City Hospital, Nottingham, United Kingdom; Alain Daban, Hôpital Jean Bernard, Poitiers, France; Hans Kaanders, University Medical Center, Nijmegen, the Netherlands; Mehmet Sen, Dokuz Eylul University School of Medicine, Izmir, Turkey; and Jacek Jassem, Medical University of Gdansk, Gdansk, Poland.
Source Information
From the Department of Radio-Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland (J. Bernier); the Department of Radio-Oncology, Institut Gustave Roussy, Villejuif, France (C.D., J. Bourhis); the Department of Radio-Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland (M.O.); the Department of Oncology and Radiotherapy, Medical University of Gdansk, Gdansk, Poland (K.M.); the Ear, Nose, and Throat Department, Centre O. Lambret, Lille, France (J.-L.L.); the Department of Radio-Oncology, Inselspital, Bern, Switzerland (R.H.G.); the Department of Radio-Oncology, Hospital General Vall d'Hebron, Barcelona, Spain (J.G.); the Department of Radio-Oncology, Centre G.F. Leclerc, Dijon, France (P.M.); the Department of Radio-Oncology, Centre R. Gauducheau, St. Herblain, France (F.R.); the Department of Radio-Oncology, Centre Hospitalier Universitaire A. Michallon, Grenoble, France (M.B.); Istituto Regina Elena, Rome (F.C.); and the European Organization for Research and Treatment of Cancer Data Center, Brussels (A.K., M.G.).
Address reprint requests to Dr. Bernier at the Department of Radio-Oncology, San Giovanni Hospital, Oncology Institute of Southern Switzerland, CH-6504 Bellinzona, Switzerland, or at jacques.bernier@hcuge.ch.
- References
References
1
Johnson JT ,Barnes EL ,Myers EN ,Scrahmm VL Jr ,Borochovitz D ,Sigler BA . The extracapsular spread of tumors in cervical node metastasis. Arch Otolaryngol 1981;107:725-729
Web of Science | Medline2
Kramer S ,Gelber RD ,Snow JB , et al. Combined radiation therapy and surgery in the management of head and neck cancer: final report of study 73-03 of the Radiation Therapy Oncology Group. Head Neck Surg 1987;10:19-30
CrossRef | Medline3
Snow GB ,Annyas AA ,van Slooten EA ,Bartelink H ,Hart AA . Prognostic factors of neck node metastasis. Clin Otolaryngol 1982;7:185-192
CrossRef | Web of Science | Medline4
Vikram B ,Strong EW ,Shah JP ,Spiro R . Failure at the primary site following multimodality treatment in advanced head and neck cancer. Head Neck Surg 1984;6:720-723
CrossRef | Medline5
Fletcher GH ,Evers WT . Radiotherapeutic management of surgical recurrences and postoperative residuals in tumors of the head and neck. Radiology 1970;95:185-188
Web of Science | Medline6
Tupchong L ,Scott CB ,Blitzer PH , et al. Randomized study of preoperative versus postoperative radiation therapy in advanced head and neck carcinoma: long-term follow-up of RTOG study 73-03. Int J Radiat Oncol Biol Phys 1991;20:21-28
CrossRef | Web of Science | Medline7
Cachin Y ,Eschwege F . Combination of radiotherapy and surgery in the treatment of head and neck cancers. Cancer Treat Rev 1975;2:177-191
CrossRef | Web of Science | Medline8
Stell PM ,Rawson NS . Adjuvant chemotherapy in head and neck cancer. Br J Cancer 1990;61:779-787
CrossRef | Web of Science | Medline9
Jassem J ,Bartelink H . Chemotherapy in locally advanced head and neck cancer: a critical reappraisal. Cancer Treat Rev 1995;21:447-462
CrossRef | Web of Science | Medline10
Jacobs C ,Makuch R . Efficacy of adjuvant chemotherapy for patients with resectable head and neck cancer: a subset analysis of Head and Neck Contracts Program. J Clin Oncol 1990;8:838-847
Web of Science | Medline11
Laramore GE ,Scott CB ,al-Sarraf M , et al. Adjuvant chemotherapy for resectable squamous cell carcinomas of the head and neck: report on Intergroup Study 0034. Int J Radiat Oncol Biol Phys 1992;23:705-713
CrossRef | Web of Science | Medline12
Bachaud JM ,David JM ,Boussin G ,Daly N . Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced squamous cell carcinoma of the head and neck: preliminary report of a randomized trial. Int J Radiat Oncol Biol Phys 1991;20:243-246
CrossRef | Web of Science | Medline13
Haffty BG ,Son YH ,Sasaki CT , et al. Mitomycin C as an adjunct to postoperative radiation therapy in squamous cell carcinoma of the head and neck: results from two randomized clinical trials. Int J Radiat Oncol Biol Phys 1993;27:241-250
Web of Science | Medline14
Spiessl B, Beahrs OH, Hermanek P, et al., eds. TNM atlas: illustrated guide to the TNM/pTNM-classification of malignant tumours. 3rd ed. Berlin: Springer-Verlag, 1989.
15
Robbins KT ,Medina JE ,Wolfe GT ,Levine PA ,Sessions RB ,Pruet CW . Standardizing neck dissection terminology: official report of the Academy's Committee for Head and Neck Surgery and Oncology. Arch Otolaryngol Head Neck Surg 1991;117:601-605
Web of Science | Medline16
Bernier J ,Wibault P ,Eschwege F , et al. Interim analysis of EORTC Phase III Trial 22931: after surgery, chemo-radiation (CRT), as compared to radiotherapy alone (RT), significantly increases disease-free survival (DFS), local control (LC) and overall survival (OS) in high-risk head and neck cancer (HNSCC) patients. Ann Oncol 2002;13:Suppl 5:9-9 abstract.17
Kaplan EL ,Meier P . Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-481
CrossRef | Web of Science18
Gray RJ . A class of K-sample tests for comparing the cumulative incidence of a competing risk. Ann Stat 1988;16:1141-1154
CrossRef | Web of Science19
Barkley HT ,Fletcher GH ,Jesse RH ,Lindberg RD . Management of cervical lymph node metastases in squamous cell carcinoma of the tonsillar fossa, base of tongue, supraglottic larynx, and hypopharynx. Am J Surg 1972;124:462-467
CrossRef | Web of Science | Medline20
Peters LJ ,Goepfert H ,Ang KK , et al. Evaluation of the dose for post-operative radiation therapy of head and neck cancer: first report of a prospective randomized trial. Int J Radiat Oncol Biol Phys 1993;26:3-11
CrossRef | Web of Science | Medline21
Rossi A ,Molinari R ,Boracchi P , et al. Adjuvant chemotherapy with vincristine, cyclophosphamide, and doxorubicin after radiotherapy in local-regional nasopharyngeal cancer: results of a 4-year multicenter randomized study. J Clin Oncol 1988;6:1401-1410
Web of Science | Medline22
Szpirglas H ,Chastang CL ,Bertrand JC . Adjuvant treatment of tongue and floor of the mouth cancer. Cancer Res 1978;68:309-31723
Huang AT ,Cole TB ,Fishburn R ,Jelovsek SB . Adjuvant chemotherapy after surgery and radiation for stage III and IV head and neck cancer. Ann Surg 1984;200:195-199
CrossRef | Web of Science | Medline24
Jacobs JR ,Pajak TF ,al-Sarraf M , et al. Chemotherapy following surgery for head and neck cancer: a Radiation Therapy Oncology Group study. Am J Clin Oncol 1989;12:185-189
CrossRef | Web of Science | Medline25
Johnson JT ,Myers EN ,Schramm VL Jr , et al. Adjuvant chemotherapy for high-risk squamous-cell carcinomas of the head and neck. J Clin Oncol 1987;5:456-458
Web of Science | Medline26
Al-Sarraf M ,Pajak TF ,Marcial VA , et al. Concurrent radiotherapy and chemotherapy with cisplatin in inoperable squamous cell carcinoma of the head and neck: an RTOG study. Cancer 1987;59:259-265
CrossRef | Web of Science | Medline27
Merlano M ,Benasso M ,Corvo R , et al. Five-year update of a randomized trial of alternating radiotherapy and chemotherapy compared with radiotherapy alone in treatment of unresectable squamous cell carcinoma of the head and neck. J Natl Cancer Inst 1996;88:583-589
CrossRef | Web of Science | Medline28
Bachaud JM ,Cohen-Jonathan E ,Alzieu C ,David JM ,Serrano E ,Daly-Schveitzer N . Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced head and neck carcinoma: final report of a randomized trial. Int J Radiat Oncol Biol Phys 1996;365:999-100429
Brizel DM ,Albers ME ,Fisher SR , et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med 1998;338:1798-1804
Full Text | Web of Science | Medline30
Wendt TG ,Grabenbauer GG ,Rodel CM , et al. Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study. J Clin Oncol 1998;16:1318-1324
Web of Science | Medline31
Calais G ,Alfonsi M ,Bardet E , et al. Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst 1999;91:2081-2086
CrossRef | Web of Science | Medline32
Pignon JP ,Bourhis J ,Domenge C ,Designe L . Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. Lancet 2000;355:949-955
CrossRef | Web of Science | Medline33
Adelstein DJ ,Rice TW ,Rybicki LA , et al. Does paclitaxel improve the chemoradiotherapy of locoregionally advanced esophageal cancer? A nonrandomized comparison with fluorouracil-based therapy. J Clin Oncol 2000;18:2032-2039
Web of Science | Medline34
Cooper JS ,Pajak TF ,Forastiere AA , et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004;350:1937-1944
Full Text | Web of Science | Medline
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Ashok Srinivasan, Thomas L. Chenevert, Ben A. Dwamena, Avraham Eisbruch, Kuanwong Watcharotone, James D. Myles, Suresh K. Mukherji. (2012) Utility of Pretreatment Mean Apparent Diffusion Coefficient and Apparent Diffusion Coefficient Histograms in Prediction of Outcome to Chemoradiation in Head and Neck Squamous Cell Carcinoma. Journal of Computer Assisted Tomography 36:1, 131-137
CrossRef5
Volker Rudat, Salia Ahmet-Osman, Oliver Schramm, Andreas Dietz. (2012) Definitive Radiotherapy versus Postoperative Radiotherapy of Patients with Oro- and Hypopharyngeal Cancer: Impact of Prognostic Factors. Journal of Oncology 2012, 1-10
CrossRef6
V. Valentini, F. Marazzi, M. Bossola, F. Miccichè, L. Nardone, M. Balducci, N. Dinapoli, P. Bonomo, R. Autorino, S. Silipigni, F. Giuliani, C. Tamanti, M. C. Mele, G. E. Martorana. (2012) Nutritional counselling and oral nutritional supplements in head and neck cancer patients undergoing chemoradiotherapy. Journal of Human Nutrition and Dieteticsno-no
CrossRef7
Miren Gaztañaga, María Pagola, Mauricio Cambeiro, Maria E. Rodriguez Ruiz, Javier Aristu, Néstor Montesdeoca, Juan Alcalde, Rafael Martínez-Monge. (2012) Comparison of limited-volume perioperative high-dose-rate brachytherapy and wide-field external irradiation in resected head and neck cancer. Head & Neckn/a-n/a
CrossRef8
Chun-Shu Lin, Yee-Min Jen, Woei-Yau Kao, Ching-Liang Ho, Ming-Shen Dai, Chia-Lin Shih, Jen-Chan Cheng, Ping-Ying Chang, Wen-Yen Huang, Yu-Fu Su. (2012) Improved outcomes in buccal squamous cell carcinoma. Head & Neckn/a-n/a
CrossRef9
H.E. Eckel. (2012) Aktuelle Therapieoptionen bei Larynx- und Hypopharynxkarzinomen. HNO 60:1, 6-18
CrossRef10
Rizwan Masood, Indrajit Roy, Sutao Zu, Christian Hochstim, Ken-Tye Yong, Wing-Cheung Law, Hong Ding, Uttam K. Sinha, Paras N. Prasad. (2012) Gold nanorod–sphingosine kinase siRNA nanocomplexes: a novel therapeutic tool for potent radiosensitization of head and neck cancer. Integrative Biology
CrossRef11
Julia A. Woolgar, Asterios Triantafyllou, Alfio Ferlito, Kenneth O. Devaney, James S. Lewis, Alessandra Rinaldo, Pieter J. Slootweg, Leon Barnes. (2012) Intraosseous carcinoma of the jaws: A clinicopathologic review. Part III: Primary intraosseous squamous cell carcinoma. Head & Neckn/a-n/a
CrossRef12
Hiroko Yanagi, Lei Wang, Hiroshi Nishihara, Taichi Kimura, Mishie Tanino, Teruki Yanagi, Satoshi Fukuda, Shinya Tanaka. (2012) CRKL plays a pivotal role in tumorigenesis of head and neck squamous cell carcinoma through the regulation of cell adhesion. Biochemical and Biophysical Research Communications
CrossRef13
Syed Nabil, Nabil Samman. (2012) Risk factors for osteoradionecrosis after head and neck radiation: a systematic review. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 113:1, 54-69
CrossRef14
Shyh-Kuan Tai, Wing-Yin Li, Muh-Hwa Yang, Shyue-Yih Chang, Pen-Yuan Chu, Tung-Lung Tsai, Yi-Fen Wang, Peter Mu-Hsin Chang. (2011) Treatment for T1-2 Oral Squamous Cell Carcinoma with or Without Perineural Invasion: Neck Dissection and Postoperative Adjuvant Therapy. Annals of Surgical Oncology
CrossRef15
Ki-Yeol Kim, In-Ho Cha. (2011) Risk stratification of oral cancer patients using a combined prognostic factor including lymph node density and biomarker. Journal of Cancer Research and Clinical Oncology
CrossRef16
Nai-Wen Su, Yi-Shing Leu, Jehn-Chuan Lee, Yu-Jen Chen, Hong-Wen Chen, Chung-Ji Liu, Yi-Fang Chang. (2011) Comparison of the efficacy and toxicity of two dose levels of cisplatin/5-fluorouracil as the chemoradiotherapy regimen for the treatment of locally advanced squamous cell carcinoma of the head and neck. Acta Oto-laryngologica 131:12, 1333-1340
CrossRef17
J.S. Brown, R.J. Shaw, F. Bekiroglu, S.N. Rogers. (2011) Systematic review of the current evidence in the use of postoperative radiotherapy for oral squamous cell carcinoma. British Journal of Oral and Maxillofacial Surgery
CrossRef18
J.J. Bonerandi, C. Beauvillain, L. Caquant, J.F. Chassagne, V. Chaussade, P. Clavère, C. Desouches, F. Garnier, J.L. Grolleau, M. Grossin, A. Jourdain, J.Y. Lemonnier, H. Maillard, N. Ortonne, E. Rio, E. Simon, J.F. Sei, J.J. Grob, L. Martin, . (2011) Guidelines for the diagnosis and treatment of cutaneous squamous cell carcinoma and precursor lesions. Journal of the European Academy of Dermatology and Venereology 25, 1-51
CrossRef19
Koji Katada, Takeshi Tomonaga, Mamoru Satoh, Kazuyuki Matsushita, Yurie Tonoike, Yoshio Kodera, Toyoyuki Hanazawa, Fumio Nomura, Yoshitaka Okamoto. (2011) Plectin promotes migration and invasion of cancer cells and is a novel prognostic marker for head and neck squamous cell carcinoma. Journal of Proteomics
CrossRef20
Miao-Fen Chen, Wen-Hung Wang, Paul- Yang Lin, Kuan-Der Lee, Wen-Cheng Chen. (2011) Significance of the TGF-beta1–IL-6 axis in oral cancer. Clinical Science
CrossRef21
M. R. Vergeer, P. A. H. Doornaert, R. de Bree, C. R. Leemans, B. J. Slotman, J. A. Langendijk. (2011) Postoperative elective nodal irradiation for squamous cell carcinoma of the head and neck: outcome and prognostic factors for regional recurrence. Annals of Oncology 22:11, 2489-2494
CrossRef22
Harold J. Wanebo, Ritesh Rathore, Prakash Chougule, Michael R. DiSiena, R. James Koness, Robert G. McRae, Peter T. Nigri, Kathy Radie-Keane, Neal Ready. (2011) Selective Organ Preservation in Operable Locally Advanced Head and Neck Squamous Cell Carcinomas Guided by Primary Site Restaging Biopsy: Long-Term Results of Two Sequential Brown University Oncology Group Chemoradiotherapy Studies. Annals of Surgical Oncology 18:12, 3479-3485
CrossRef23
V. Espeli, E. Zucca, M. Ghielmini, O. Giannini, A. Salatino, F. Martucci, A. Richetti. (2011) Weekly and 3-weekly cisplatin concurrent with intensity-modulated radiotherapy in locally advanced head and neck squamous cell cancer. Oral Oncology
CrossRef24
Chad E. Galer, Daisuke Sano, Sukhen C. Ghosh, Jeong H. Hah, Edmund Auzenne, Amirali N. Hamir, Jeffrey N. Myers, Jim Klostergaard. (2011) Hyaluronic acid–paclitaxel conjugate inhibits growth of human squamous cell carcinomas of the head and neck via a hyaluronic acid-mediated mechanism. Oral Oncology 47:11, 1039-1047
CrossRef25
Frank Hoebers, Wilma Heemsbergen, Suzanne Moor, Marta Lopez, Martin Klop, Margot Tesselaar, Coen Rasch. (2011) Reirradiation for Head-and-Neck Cancer: Delicate Balance Between Effectiveness and Toxicity. International Journal of Radiation Oncology*Biology*Physics 81:3, e111-e118
CrossRef26
Rafael Martínez-Monge, María Pagola Divassón, Mauricio Cambeiro, Miren Gaztañaga, Marta Moreno, Leire Arbea, Néstor Montesdeoca, Juan Alcalde. (2011) Determinants of Complications and Outcome in High-Risk Squamous Cell Head-and-Neck Cancer Treated With Perioperative High–Dose Rate Brachytherapy (PHDRB). International Journal of Radiation Oncology*Biology*Physics 81:4, e245-e254
CrossRef27
David J. Sher, Vijaya Thotakura, Tracy A. Balboni, Charles M. Norris, Robert I. Haddad, Marshall R. Posner, Jochen Lorch, Laura A. Goguen, Donald J. Annino, Roy B. Tishler. (2011) Treatment of Oral Cavity Squamous Cell Carcinoma With Adjuvant or Definitive Intensity-Modulated Radiation Therapy. International Journal of Radiation Oncology*Biology*Physics 81:4, e215-e222
CrossRef28
Chun-Ta Liao, Li-Yu Lee, Shiang-Fu Huang, I-How Chen, Chung-Jan Kang, Chien-Yu Lin, Kang-Hsing Fan, Hung-Ming Wang, Shu-Hang Ng, Tzu-Chen Yen. (2011) Outcome Analysis of Patients With Oral Cavity Cancer and Extracapsular Spread in Neck Lymph Nodes. International Journal of Radiation Oncology*Biology*Physics 81:4, 930-937
CrossRef29
Florian Clatot, Jean-Michel Picquenot, Olivier Choussy, Sophie Gouérant, Cristian Moldovan, Didier Schultheis, Marie Cornic, Arnaud François, Emmanuel Blot, Sophie Laberge-Le-Couteulx. (2011) Intratumoural level of SDF-1 correlates with survival in head and neck squamous cell carcinoma. Oral Oncology 47:11, 1062-1068
CrossRef30
Sagar C. Patel, Trevor Hackman, David Neil Hayes, Bhishamjit S. Chera. (2011) De-intensification of treatment for human papilloma virus associated oropharyngeal squamous cell carcinoma: A discussion of current approaches. Practical Radiation Oncology
CrossRef31
Julia Maurer, Matthias Hipp, Christof Schäfer, Oliver Kölbl. (2011) Dysphagia. Strahlentherapie und Onkologie
CrossRef32
Kevin S. Choe, Daniel J. Haraf, Abhishek Solanki, Ezra E. W. Cohen, Tanguy Y. Seiwert, Kerstin M. Stenson, Elizabeth A. Blair, Louis Portugal, Victoria M. Villaflor, Mary Ellyn Witt, Everett E. Vokes, Joseph K. Salama. (2011) Prior chemoradiotherapy adversely impacts outcomes of recurrent and second primary head and neck cancer treated with concurrent chemotherapy and reirradiation. Cancer 117:20, 4671-4678
CrossRef33
T. Yokota, Y. Onozawa, N. Boku, S. Hamauchi, T. Tsushima, H. Taniguchi, A. Todaka, N. Machida, K. Yamazaki, A. Fukutomi, H. Yasui. (2011) S-1 Monotherapy for Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck After Progression on Platinum-based Chemotherapy. Japanese Journal of Clinical Oncology
CrossRef34
Ryota Nishio, Kazuhiro Saito, Hiroyuki Ito, Tomoyuki Yoshida, Koichi Kitamura, Akira Shimizu, Naoto Kanesaka, Ryuji Mikami, Daisuke Hasegawa, Mamoru Suzuki, Koichi Tokuuye. (2011) Selective intraarterial chemoradiation therapy for oropharyngeal carcinoma with high-dose cisplatin. Japanese Journal of Radiology 29:8, 570-575
CrossRef35
Chiao-Ying Lin, Szu-Ta Chen, Yung-Ming Jeng, Cheng-Chang Yeh, Han-Yi Chou, Yi-Ting Deng, Cheng-Chi Chang, Mark Yen-Ping Kuo. (2011) Insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor formation and invasion and predicts poor prognosis in oral squamous cell carcinoma. Journal of Oral Pathology & Medicine 40:9, 699-705
CrossRef36
Allen M. Chen, D. Gregory Farwell, Derick H. Lau, Bao-Qing Li, Quang Luu, Paul J. Donald. (2011) Radiation Therapy in the Management of Head-and-Neck Cancer of Unknown Primary Origin: How Does the Addition of Concurrent Chemotherapy Affect the Therapeutic Ratio?. International Journal of Radiation Oncology*Biology*Physics 81:2, 346-352
CrossRef37
S.S. Gill, J. Frew, A. Fry, J. Adam, V. Paleri, W. Dobrowsky, S. Chatterjee, C.G. Kelly. (2011) Priorities for the Head and Neck Cancer Patient, their Companion and Members of the Multidisciplinary Team and Decision Regret. Clinical Oncology 23:8, 518-524
CrossRef38
Barbara A. Murphy, Jill Gilbert. (2011) Oral cancers: supportive care issues. Periodontology 2000 57:1, 118-131
CrossRef39
Eric Assenat, Simon Thezenas, Nicolas Flori, Nicole Pere-Charlier, Renaud Garrel, Antoine Serre, David Azria, Pierre Senesse. (2011) Prophylactic Percutaneous Endoscopic Gastrostomy in Patients With Advanced Head and Neck Tumors Treated by Combined Chemoradiotherapy. Journal of Pain and Symptom Management 42:4, 548-556
CrossRef40
Christine H. Chung, Qiang Zhang, Elizabeth M. Hammond, Andy M. Trotti, Huijun Wang, Sharon Spencer, Hua-Zhong Zhang, Jay Cooper, Richard Jordan, Marvin H. Rotman, K. Kian Ang. (2011) Integrating Epidermal Growth Factor Receptor Assay With Clinical Parameters Improves Risk Classification for Relapse and Survival in Head-and-Neck Squamous Cell Carcinoma. International Journal of Radiation Oncology*Biology*Physics 81:2, 331-338
CrossRef41
Juhani Collan, Marie Lundberg, Leila Vaalavirta, Leif Bäck, Mikael Kajanti, Antti Mäkitie, Mikko Tenhunen, Kauko Saarilahti. (2011) Patterns of relapse following surgery and postoperative intensity modulated radiotherapy for oral and oropharyngeal cancer. Acta Oncologica 50:7, 1119-1125
CrossRef42
Francesca Martinelli, Chantal Quinten, John T Maringwa, Corneel Coens, Jurgen Vercauteren, Charles S Cleeland, Henning Flechtner, Carolyn Gotay, Eva Greimel, Madeleine King, Tito Mendoza, David Osoba, Bryce B Reeve, Jolie Ringash, Joseph Schmucker-Von Koch, Qiuling Shi, Martin J Taphoorn, Joachim Weis, Andrew Bottomley. (2011) Examining the relationships among health-related quality-of-life indicators in cancer patients participating in clinical trials: a pooled study of baseline EORTC QLQ-C30 data. Expert Review of Pharmacoeconomics & Outcomes Research 11:5, 587-599
CrossRef43
Matthias Kreppel, Uta Drebber, Daniel Rothamel, Hans-Theodor Eich, Alexander Kübler, Martin Scheer, Joachim E. Zöller. (2011) Prognostic impact of different TNM-based stage groupings for oral squamous cell carcinoma. Head & Neck 33:10, 1467-1475
CrossRef44
Suneetha Devpura, Jagdish S. Thakur, Seema Sethi, Vaman M. Naik, Ratna Naik. (2011) Diagnosis of head and neck squamous cell carcinoma using Raman spectroscopy: tongue tissues. Journal of Raman Spectroscopyn/a-n/a
CrossRef45
Martina A. Broglie, Sarah R. Haile, Sandro J. Stoeckli. (2011) Long-Term Experience in Sentinel Node Biopsy for Early Oral and Oropharyngeal Squamous Cell Carcinoma. Annals of Surgical Oncology 18:10, 2732-2738
CrossRef46
Sadamoto Zenda, Kazuto Matsuura, Hiroyuki Tachibana, Akihiro Homma, Tadaaki Kirita, Nobuya Monden, Shigemichi Iwae, Yojiro Ota, Tetsuo Akimoto, Hiroshi Otsuru, Makoto Tahara, Kengo Kato, Masao Asai. (2011) Multicenter phase II study of an opioid-based pain control program for head and neck cancer patients receiving chemoradiotherapy. Radiotherapy and Oncology
CrossRef47
Matthew G. Fury, Eric Sherman, Sofia Haque, Susan Korte, Donna Lisa, Ronglai Shen, Nian Wu, David Pfister. (2011) A phase I study of daily everolimus plus low-dose weekly cisplatin for patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology
CrossRef48
Wu-Chia Lo, Cheng-Ping Wang, Jeng-Yuh Ko, Pei-Jen Lou, Tsung-Lin Yang, Chun-Wei Wang, Ya-Ling Hu, Tseng-Cheng Chen. (2011) Salvage Treatment for Isolated Regional Failure of Nasopharyngeal Carcinoma after Primary Radiotherapy. Annals of Surgical Oncology
CrossRef49
Alyson Bessell, Anne-Marie Glenny, Susan Furness, Jan E Clarkson, Richard Oliver, David I Conway, Michaelina Macluskey, Sue Pavitt, Philip Sloan, Helen V Worthington, Alyson Bessell. 2011. Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment. .
CrossRef50
Farzan Siddiqui, David Raben, Jiade J Lu, John C Grecula, Simon S Lo, Zhibin Huang, Nina A Mayr, Bin S Teh, Min Yao. (2011) Emerging applications of stereotactic body radiation therapy for head and neck cancer. Expert Review of Anticancer Therapy 11:9, 1429-1436
CrossRef51
H Deng, PJ Sambrook, RM Logan. (2011) The treatment of oral cancer: an overview for dental professionals. Australian Dental Journal 56:3, 244-252
CrossRef52
David I PRYOR, Benjamin SOLOMON, Sandro V PORCEDDU. (2011) The emerging era of personalized therapy in squamous cell carcinoma of the head and neck. Asia-Pacific Journal of Clinical Oncology 7:3, 236-251
CrossRef53
Chun-Ta Liao, Chien-Yu Lin, Kang-Hsing Fan, Shiang-Fu Huang, I-How Chen, Chung-Jan Kang, Hung-Ming Wang, Shu-Hang Ng, Chuen Hsueh, Li-Yu Lee, Chih-Hung Lin, Tzu-Chen Yen. (2011) Identification of a High-Risk Subgroup of Patients with Resected pT3 Oral Cavity Cancer in Need of Postoperative Adjuvant Therapy. Annals of Surgical Oncology 18:9, 2569-2578
CrossRef54
Zulfiquer OTTY, Monika Buhrer SKINNER, Joshua DASS, Michael COLLINS, Jennifer MOOI, Kandeepan THURAISINGAM, Sabe SABESAN. (2011) Efficacy and tolerability of weekly low-dose cisplatin concurrent with radiotherapy in head and neck cancer patients. Asia-Pacific Journal of Clinical Oncology 7:3, 287-292
CrossRef55
Matthias Kreppel, Uta Drebber, Hans-Theodor Eich, Timo Dreiseidler, Joachim E. Zöller, Rolf-Peter Müller, Martin Scheer. (2011) Combined-modality treatment in advanced oral squamous cell carcinoma. Strahlentherapie und Onkologie 187:9, 555-560
CrossRef56
Sung Ho Moon, Yuh-Seog Jung, Jun Sun Ryu, Sung Weon Choi, Joo Yong Park, Tak Yun, Sang Hyun Lee, Kwan Ho Cho. (2011) Outcomes of Postoperative Simultaneous Modulated Accelerated Radiotherapy for Head-and-Neck Squamous Cell Carcinoma. International Journal of Radiation Oncology*Biology*Physics 81:1, 140-149
CrossRef57
K J Harrington, L J Billingham, T B Brunner, N G Burnet, C S Chan, P Hoskin, R I Mackay, T S Maughan, J Macdougall, W G McKenna, C M Nutting, A Oliver, R Plummer, I J Stratford, T Illidge. (2011) Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers. British Journal of Cancer 105:5, 628-639
CrossRef58
E. Assenat, M. Latournerie, S. Thézenas, S. Gaillet, C. Janiszewski, N. Flori, A.M. Dupuy, D. Azria, E. Crapez, R. Garrel, P. Senesse. (2011) A prospective phase II study evaluating the efficacy of oral immune modulating formulae on acute oral mucositis during radiochemotherapy in head and neck neoplasms. e-SPEN, the European e-Journal of Clinical Nutrition and Metabolism 6:4, e171-e177
CrossRef59
G. Maschmeyer, K. Koch, M. Jungehülsing. (2011) Kopf-Hals-Tumoren. best practice onkologie 6:4, 4-20
CrossRef60
Alexandra Brentani, Gilberto de Castro, Miriam H. Federico. (2011) Cost-effectiveness analysis of cisplatin-based chemoradiation to treat patients with unresectable, nonmetastatic head and neck cancer in Brazil. Head & Neck 33:8, 1199-1205
CrossRef61
Mark W. McDonald, Joshua Lawson, Madhur Kumar Garg, Harry Quon, John A. Ridge, Nabil Saba, Joseph K. Salama, Richard V. Smith, Anamaria Reyna Yeung, Sue S. Yom, Jonathan J. Beitler. (2011) ACR Appropriateness Criteria® Retreatment of Recurrent Head and Neck Cancer After Prior Definitive Radiation. International Journal of Radiation Oncology*Biology*Physics 80:5, 1292-1298
CrossRef62
Gregory J. Kubicek, Bruce F. Kimler, Fen Wang, Eashwer K. Reddy, Douglas A. Girod, Steven K. Williamson. (2011) Chemotherapy in Head and Neck Cancer. American Journal of Clinical Oncology 34:4, 380-384
CrossRef63
Catherine Fortpied, Cecilia Liberatoscioli, Jan Bogaerts. (2011) Design issues in head and neck clinical trials. Anti-Cancer Drugs 22:7, 682-687
CrossRef64
Jean-Claude M. Rwigema, Dwight E. Heron, Robert L. Ferris, Regiane S. Andrade, Michael K. Gibson, Yong Yang, Cihat Ozhasoglu, Athanassios E. Argiris, Jennifer R. Grandis, Steven A. Burton. (2011) The Impact of Tumor Volume and Radiotherapy Dose on Outcome in Previously Irradiated Recurrent Squamous Cell Carcinoma of the Head and Neck Treated With Stereotactic Body Radiation Therapy. American Journal of Clinical Oncology 34:4, 372-379
CrossRef65
Megan E. Daly, Quynh-Thu Le, Margaret M. Kozak, Peter G. Maxim, James D. Murphy, Annie Hsu, Billy W. Loo, Michael J. Kaplan, Nancy J. Fischbein, Daniel T. Chang. (2011) Intensity-Modulated Radiotherapy for Oral Cavity Squamous Cell Carcinoma: Patterns of Failure and Predictors of Local Control. International Journal of Radiation Oncology*Biology*Physics 80:5, 1412-1422
CrossRef66
M. Ishizuka, Y. Fujimoto, Y. Itoh, K. Kitagawa, M. Sano, Y. Miyagawa, A. Ando, M. Hiramatsu, N. Hirasawa, S. Ishihara, T. Nakashima, K. Yamada. (2011) Relationship Between Hematotoxicity and Serum Albumin Level in the Treatment of Head and Neck Cancers with Concurrent Chemoradiotherapy Using Cisplatin. Japanese Journal of Clinical Oncology 41:8, 973-979
CrossRef67
Peng Xie, Minghuan Li, Hanxi Zhao, Xindong Sun, Zheng Fu, Jinming Yu. (2011) 18F-FDG PET or PET-CT to evaluate prognosis for head and neck cancer: a meta-analysis. Journal of Cancer Research and Clinical Oncology 137:7, 1085-1093
CrossRef68
Jacques Tortochaux, Yungan Tao, Elodie Tournay, Michel Lapeyre, Francois Lesaunier, Etienne Bardet, François Janot, Antoine Lusinchi, Ellen Benhamou, Patrick Bontemps, Philippe Maingon, Gilles Calais, Nicolas Daly-Schveitzer, Pierre Verrelle, Jean Bourhis. (2011) Randomized phase III trial (GORTEC 98-03) comparing re-irradiation plus chemotherapy versus methotrexate in patients with recurrent or a second primary head and neck squamous cell carcinoma, treated with a palliative intent. Radiotherapy and Oncology 100:1, 70-75
CrossRef69
Joseph K. Salama, Nabil Saba, Harry Quon, Madhur Kumar Garg, Joshua Lawson, Mark W. McDonald, John A. Ridge, Richard V. Smith, Anamaria Reyna Yeung, Sue S. Yom, Jonathan J. Beitler. (2011) ACR appropriateness criteria® adjuvant therapy for resected squamous cell carcinoma of the head and neck. Oral Oncology 47:7, 554-559
CrossRef70
Sohit Paul Kanotra, Sonika Kanotra, Ashutosh Gupta, J. Paul. (2011) Chemoradiation in Advanced Head and Neck Cancers: A Comparison of two Radiosensitizers, Paclitaxel and Cisplatin. Indian Journal of Otolaryngology and Head & Neck Surgery 63:3, 229-236
CrossRef71
Alexander J. Hassel, Daniel Danner, Kolja Freier, Christof Hofele, Kirsten Becker-Bikowski, Michael Engel. (2011) Oral health-related quality of life and depression/anxiety in long-term recurrence-free patients after treatment for advanced oral squamous cell cancer. Journal of Cranio-Maxillofacial Surgery
CrossRef72
Björn Zackrisson, Per Nilsson, Elisabeth Kjellén, Karl-Axel Johansson, Hans Modig, Eva Brun, Jan Nyman, Signe Friesland, Johan Reizenstein, Helena Sjödin, Lars Ekberg, Britta Lödén, Claes Mercke, Jan-Olof Fernberg, Lars Franzén, Anders Ask, Essie Persson, Gun Wickart-Johansson, Freddi Lewin, Lena Wittgren, Ove Björ, Thomas Björk-Eriksson. (2011) Two-year results from a Swedish study on conventional versus accelerated radiotherapy in head and neck squamous cell carcinoma – The ARTSCAN study. Radiotherapy and Oncology 100:1, 41-48
CrossRef73
Dirk Rades, Stefanie Kronemann, Thekla Meyners, Guenther Bohlen, Silke Tribius, Nadja Kazic, Ursula Schroeder, Samer G. Hakim, Steven E. Schild, Juergen Dunst. (2011) Comparison of Four Cisplatin-Based Radiochemotherapy Regimens for Nonmetastatic Stage III/IV Squamous Cell Carcinoma of the Head and Neck. International Journal of Radiation Oncology*Biology*Physics 80:4, 1037-1044
CrossRef74
Maximilian Moergel, Philipp Meurer, Katharina Ingel, Thomas G. Wendt, Bilal Al-Nawas. (2011) Effectiveness of postoperative radiotherapy in patients with small oral and oropharyngeal squamous cell carcinoma and concomitant ipsilateral singular cervical lymph node metastasis (pN1). Strahlentherapie und Onkologie 187:6, 337-343
CrossRef75
Chih-Chin Liu, Rui Xia, Ashleigh Guadagnolo, Janice N Cormier, Xianglin L Du. (2011) Risk of Xerostomia in Association With the Receipt of Radiation Therapy in Older Patients With Head and Neck Cancer. American Journal of Therapeutics 18:3, 206-215
CrossRef76
Thomas Kuhnt, Ulf Klockenbrink, Stephan Knipping, Juergen Lautermann, Karen Kriese, Andreas Wienke, Guido Hildebrandt, Steffen Hauptmann. (2011) Adjuvant Low Single Dose Cisplatin-based Concurrent Radiochemotherapy of Oral Cavity and Oropharynx Carcinoma. Strahlentherapie und Onkologie 187:5, 292-299
CrossRef77
Paolo Boscolo-Rizzo, Alessandro Gava, Vittorio Baggio, Carlo Marchiori, Marco Stellin, Roberto Fuson, Stefano Lamon, Maria Cristina Da Mosto. (2011) Matched Survival Analysis in Patients With Locoregionally Advanced Resectable Oropharyngeal Carcinoma: Platinum-Based Induction and Concurrent Chemoradiotherapy Versus Primary Surgical Resection. International Journal of Radiation Oncology*Biology*Physics 80:1, 154-160
CrossRef78
Amita Shukla-Dave, Nancy Y. Lee, Jacobus F.A. Jansen, Howard T. Thaler, Hilda E. Stambuk, Matthew G. Fury, Snehal G. Patel, Andre L. Moreira, Eric Sherman, Sasan Karimi, Ya Wang, Dennis Kraus, Jatin P. Shah, David G. Pfister, Jason A. Koutcher. (2011) Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a Predictor of Outcome in Head and Neck Squamous Cell Carcinoma Patients with Nodal Metastases. International Journal of Radiation Oncology*Biology*Physics
CrossRef79
Jeremy P. Watkins, Glenn B. Williams, Anthony A. Mascioli, Jim Y. Wan, Sandeep Samant. (2011) Shoulder function in patients undergoing selective neck dissection with or without radiation and chemotherapy. Head & Neck 33:5, 615-619
CrossRef80
Stuart J. Wong, Paul M. Harari, Adam S. Garden, Marc Schwartz, Lisa Bellm, Amy Chen, Walter J. Curran, Barbara A. Murphy, K. Kian Ang. (2011) Longitudinal oncology registry of head and neck carcinoma (LORHAN). Cancer 117:8, 1679-1686
CrossRef81
Susan Furness, Anne-Marie Glenny, Helen V Worthington, Sue Pavitt, Richard Oliver, Jan E Clarkson, Michaelina Macluskey, Kelvin KW Chan, David I Conway, Susan Furness. 2011. Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy. .
CrossRef82
Mario Airoldi, Massimiliano Garzaro, Luca Raimondo, Giancarlo Pecorari, Carlo Giordano, Antonella Varetto, Paola Caldera, Riccardo Torta. (2011) Functional and psychological evaluation after flap reconstruction plus radiotherapy in oral cancer. Head & Neck 33:4, 458-468
CrossRef83
Amber G. Brannan, Peter A. S. Johnstone, Jay Cooper. (2011) Extracapsular tumor extension in cervical lymph nodes: Reconciling the literature and seer data. Head & Neck 33:4, 525-528
CrossRef84
Marc A. Cohen, Gregory S. Weinstein, Bert W. O'Malley, Michael Feldman, Harry Quon. (2011) Transoral robotic surgery and human papillomavirus status: Oncologic results. Head & Neck 33:4, 573-580
CrossRef85
Pol Specenier, Jan B Vermorken. (2011) Cetuximab in the treatment of squamous cell carcinoma of the head and neck. Expert Review of Anticancer Therapy 11:4, 511-524
CrossRef86
Charles Woods, Jason Sohn, Min Yao. (2011) The Application of PET in Radiation Treatment Planning for Head and Neck Cancer. PET Clinics 6:2, 149-163
CrossRef87
H. Daiko, R. Hayashi, M. Sakuraba, M. Ebihara, M. Miyazaki, T. Shinozaki, M. Saikawa, S. Zenda, M. Kawashima, M. Tahara, T. Doi, A. Ohtsu. (2011) A Pilot Study of Post-operative Radiotherapy with Concurrent Chemotherapy for High-risk Squamous Cell Carcinoma of the Cervical Esophagus. Japanese Journal of Clinical Oncology 41:4, 508-513
CrossRef88
Jack H. Mydlo. (2011) The Quest for Improved Management of Penile Cancer. The Journal of Urology 185:3, 774-776
CrossRef89
Niels M. Graafland, Luc M.F. Moonen, Hester H. van Boven, Erik van Werkhoven, J. Martijn Kerst, Simon Horenblas. (2011) Inguinal Recurrence Following Therapeutic Lymphadenectomy for Node Positive Penile Carcinoma: Outcome and Implications for Management. The Journal of Urology 185:3, 888-894
CrossRef90
Luca Calabrese, Roberto Bruschini, Gioacchino Giugliano, Angelo Ostuni, Fausto Maffini, Maria Angela Massaro, Luigi Santoro, Valeria Navach, Lorenzo Preda, Daniela Alterio, Mohssen Ansarin, Fausto Chiesa. (2011) Compartmental tongue surgery: Long term oncologic results in the treatment of tongue cancer. Oral Oncology 47:3, 174-179
CrossRef91
M. Rampino, U. Ricardi, F. Munoz, A. Reali, C. Barone, A.R. Musu, V. Balcet, P. Franco, R. Grillo, S. Bustreo, G. Pecorari, A. Cavalot, P. Garzino Demo, L. Ciuffreda, R. Ragona, M. Schena. (2011) Concomitant Adjuvant Chemoradiotherapy with Weekly Low-dose Cisplatin for High-risk Squamous Cell Carcinoma of the Head and Neck: a Phase II Prospective Trial. Clinical Oncology 23:2, 134-140
CrossRef92
Sorcha Campbell, Ian Poon, Dan Markel, Dan Vena, Kevin Higgins, Dan Enepekides, Simon Rapheal, John Wong, Ghassan Allo, Eric Morgen. (2011) Evaluation of Microscopic Disease in Oral Tongue Cancer Using Whole-Mount Histopathologic Techniques: Implications for the Management of Head-and-Neck Cancers. International Journal of Radiation OncologyBiologyPhysics
CrossRef93
Elisabeth Rudolph, Gerhard Dyckhoff, Heiko Becher, Andreas Dietz, Heribert Ramroth. (2011) Effects of tumour stage, comorbidity and therapy on survival of laryngeal cancer patients: a systematic review and a meta-analysis. European Archives of Oto-Rhino-Laryngology 268:2, 165-179
CrossRef94
Johnny Kao, Eric M. Genden, Vishal Gupta, Edelweiss L. Policarpio, Ryan J. Burri, Michael Rivera, Vivek Gurudutt, Peter M. Som, Marita Teng, Stuart H. Packer. (2011) Phase 2 trial of concurrent 5-fluorouracil, hydroxyurea, cetuximab, and hyperfractionated intensity-modulated radiation therapy for locally advanced head and neck cancer. Cancer 117:2, 318-326
CrossRef95
Aijun Sun, Silvia Johansson, Ingela Turesson, Alexandru Daşu, Jens Sörensen. (2011) Imaging Tumor Perfusion and Oxidative Metabolism in Patients with Head-and-neck Cancer using 1- [11C]-acetate PET during Radiotherapy: Preliminary Results. International Journal of Radiation OncologyBiologyPhysics
CrossRef96
Anja C Pickhard, Johanna Margraf, Andreas Knopf, Thomas Stark, Guido Piontek, Carolin Beck, Anne-Laure Boulesteix, Elias Q Scherer, Steffi Pigorsch, Jürgen Schlegel, Wolfgang Arnold, Rudolf Reiter. (2011) Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways. BMC Cancer 11:1, 388
CrossRef97
Harry Quon, Bert W. O’Malley, Jr., Gregory S. Weinstein. (2011) Postoperative Adjuvant Therapy after Transoral Robotic Resection for Oropharyngeal Carcinomas: Rationale and Current Treatment Approach. ORL 73:3, 121-130
CrossRef98
Vivek V. Gurudutt, Eric M. Genden. (2011) Cutaneous Squamous Cell Carcinoma of the Head and Neck. Journal of Skin Cancer 2011, 1-10
CrossRef99
Takahito Kondo, Hiroyuki Ito, Kiyoaki Tsukahara, Akira Shimizu, Isaku Okamoto, Takuro Okada, Tomoyuki Yoshida, Mamoru Suzuki. (2011) Clinical Study of Hypopharyngeal Squamous Cell Carcinoma. Nihon Kikan Shokudoka Gakkai Kaiho 62:4, 384-392
CrossRef100
Naohiro KODANI, Hideya YAMAZAKI, Takuji TSUBOKURA, Hiroya SHIOMI, Kana KOBAYASHI, Takuya NISHIMURA, Norihiro AIBE, Hiroyasu IKENO, Tsunehiko NISHIMURA. (2011) Stereotactic Body Radiation Therapy for Head and Neck Tumor: Disease Control and Morbidity Outcomes. Journal of Radiation Research 52:1, 24-31
CrossRef101
Perle Ernoux-Neufcoeur, Mohammad Arafa, Christine Decaestecker, Anaëlle Duray, Myriam Remmelink, Xavier Leroy, Michael Herfs, Joan Somja, Christophe E. Depuydt, Philippe Delvenne, Sven Saussez. (2011) Combined analysis of HPV DNA, p16, p21 and p53 to predict prognosis in patients with stage IV hypopharyngeal carcinoma. Journal of Cancer Research and Clinical Oncology 137:1, 173-181
CrossRef102
John D. Hainsworth, David R. Spigel, F. Anthony Greco, Dianna L. Shipley, James Peyton, Mark Rubin, Michael Stipanov, Anthony Meluch. (2011) Combined Modality Treatment With Chemotherapy, Radiation Therapy, Bevacizumab, and Erlotinib in Patients With Locally Advanced Squamous Carcinoma of the Head and Neck. The Cancer Journal 17:5, 267
CrossRef103
Yu-Min Liao, Charles Kim, Yun Yen. (2011) Mammalian target of rapamycin and head and neck squamous cell carcinoma. Head & Neck Oncology 3:1, 22
CrossRef104
Nerina Denaro, Elvio G. Russi, Vincenzo Adamo, Ida Colantonio, Marco C. Merlano. (2011) Postoperative Therapy in Head and Neck Cancer: State of the Art, Risk Subset, Prognosis and Unsolved Questions. Oncology 81:1, 21-29
CrossRef105
Michiel W. M. van den Brekel, Wouter L. Lodder, Herbert V. Stel, Elisabeth Bloemena, C. René Leemans, Isaäc van der Waal. (2011) Observer variation in the histopathologic assessment of extranodal tumor spread in lymph node metastases in the neck. Head & Neckn/a-n/a
CrossRef106
Merrill S. Kies, Dowin H. Boatright, Guojun Li, George Blumenschein, Adel K. El-Naggar, G. Brandon Gunn, Jan S. Lewin, Ganene D. Steinhaus, Erich M. Sturgis. (2011) Phase II trial of induction chemotherapy followed by surgery for squamous cell carcinoma of the oral tongue in young adults. Head & Neckn/a-n/a
CrossRef107
Thomas J. Ow, Jeffrey N. Myers. (2011) Current Management of Advanced Resectable Oral Cavity Squamous Cell Carcinoma. Clinical and Experimental Otorhinolaryngology 4:1, 1
CrossRef108
Marcus M. Monroe, Eric C. Anderson, Daniel R. Clayburgh, Melissa H. Wong. (2011) Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma. Journal of Oncology 2011, 1-8
CrossRef109
Takenori Ogawa, Kazuto Matsuura, Kiyoto Shiga, Masaru Tateda, Katsunori Katagiri, Kengo Kato, Shigeru Saijo, Toshimitsu Kobayashi. (2011) Surgical Treatment Is Recommended for Advanced Oral Squamous Cell Carcinoma. The Tohoku Journal of Experimental Medicine 223:1, 17-25
CrossRef110
Wen-Yi Wang, Yi-Chih Chien, Yong-Kie Wong, Yan-Liang Lin, Jin-Ching Lin. (2011) Effects of KRAS mutation and polymorphism on the risk and prognosis of oral squamous cell carcinoma. Head & Neckn/a-n/a
CrossRef111
Lewis Rosenberg, Mark Weissler, D. Neil Hayes, William Shockley, Adam Zanation, Julian Rosenman, Bhishamjit Chera. (2011) Concurrent chemoradiotherapy for locoregionally advanced salivary gland malignancies. Head & Neckn/a-n/a
CrossRef112
Shyh-Kuan Tai, Wing-Yin Li, Pen-Yuan Chu, Shyue-Yih Chang, Tung-Lung Tsai, Yi-Fen Wang, Jui-Lin Huang. (2011) Risks and clinical implications of perineural invasion in T1-2 oral tongue squamous cell carcinoma. Head & Neckn/a-n/a
CrossRef113
Henrik Hauswald, Christian Simon, Simone Hecht, Juergen Debus, Katja Lindel. (2011) Long-term outcome and patterns of failure in patients with advanced head and neck cancer. Radiation Oncology 6:1, 70
CrossRef114
Parul Sinha, James S. Lewis, Jay F. Piccirillo, Dorina Kallogjeri, Bruce H. Haughey. (2011) Extracapsular spread and adjuvant therapy in human papillomavirus-related, p16-positive oropharyngeal carcinoma. Cancern/a-n/a
CrossRef115
Kengo Kato, Kazuto Matsuura, Sadamoto Zenda, Hiroyuki Tachibana, Akihiro Homma, Tadaaki Kirita, Nobuya Monden, Yojiro Ota, Shigemichi Iwae, Hiroshi Otsuru, Tetsuo Akimoto, Makoto Tahara, Masao Asai. (2011) An opioid-based pain control program for head and neck cancer patients undergoing chemoradiation therapy achieves a high completion rate of radiation. Toukeibu Gan 37:1, 153-157
CrossRef116
Hideki Nishimura, Ryohei Sasaki, Takeshi Yoshida, Daisuke Miyawaki, Naki Otsuki, Miki Sitou, Naomi Kiyota, Synsuke Soejima, Kajurou Sugimura, Ken-ichi Nibu. (2011) Post-operative radiation therapy for locally advanced hypopharyngeal carcinoma. Toukeibu Gan 37:1, 62-66
CrossRef117
Naomi Kiyota. (2011) Approaches to encourage broad use of adjuvant chemoradiotherapy for postoperative high-risk patients with squamous cell carcinoma of the head and neck in Japan. Toukeibu Gan 37:3, 362-365
CrossRef118
Koji Ebisumoto, Kenji Okami, Akihiro Sakai, Taku Atsumi, Daisuke Maki, Ryosuke Sugimoto, Masahiro Iida. (2011) Clinical outcome of patients with oropharyngeal squamous cell carcinoma. Toukeibu Gan 37:3, 405-410
CrossRef119
Valesca P Retel, Lisette van der Molen, Frans JM Hilgers, Coen RN Rasch, Annemiek AAMHJ l'Ortye, Lotte MG Steuten, Wim H van Harten. (2011) A cost-effectiveness analysis of a preventive exercise program for patients with advanced head and neck cancer treated with concomitant chemo-radiotherapy. BMC Cancer 11:1, 475
CrossRef120
Yuan Wang, Thomas J. Ow, Jeffrey N. Myers. (2011) Pathways for cervical metastasis in malignant neoplasms of the head and neck region. Clinical Anatomyn/a-n/a
CrossRef121
Ian Ganly, Snehal Patel, Jatin Shah. (2011) Early stage squamous cell cancer of the oral tongue-clinicopathologic features affecting outcome. Cancern/a-n/a
CrossRef122
Catherine H. McHugh, Dianna B. Roberts, Adel K. El-Naggar, Ehab Y. Hanna, Adam S. Garden, Merrill S. Kies, Randal S. Weber, Michael E. Kupferman. (2011) Prognostic factors in mucoepidermoid carcinoma of the salivary glands. Cancern/a-n/a
CrossRef123
Kazuto Matsuura, Shun Sagai, Katsunori Katagiri, Takayuki Imai, Eiichi Ishida, Kiyoto Shiga, Shigeru Saijo. (2011) Efficacy and safety of chemoradiotherapy when performed by head and neck surgeon. Toukeibu Gan 37:4, 454-459
CrossRef124
Fernando Danelon Leonhardt, Harry Quon, Marcio Abrahão, Bert W. O'Malley, Gregory S. Weinstein. (2011) Transoral robotic surgery for oropharyngeal carcinoma and its impact on patient-reported quality of life and function. Head & Neckn/a-n/a
CrossRef125
Michael E. Montejo, Dennis C. Shrieve, Brandon G. Bentz, Jason P. Hunt, Luke O. Buchman, Neeraj Agarwal, Ying J. Hitchcock. (2010) IMRT With Simultaneous Integrated Boost and Concurrent Chemotherapy for Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck. International Journal of Radiation OncologyBiologyPhysics
CrossRef126
Aline Gouvêa de Lima, Rosângela Correa Villar, Gilberto de Castro Jr., Reynaldo Antequera, Erlon Gil, Mauro Cabral Rosalmeida, Miriam Hatsue Honda Federico, Igor Moisés Longo Snitcovsky. (2010) Oral Mucositis Prevention by Low-Level Laser Therapy in Head-and-Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy: A Phase III Randomized Study. International Journal of Radiation OncologyBiologyPhysics
CrossRef127
Luca Calabrese, Angelo Ostuni, Mohssen Ansarin, Gioacchino Giugliano, Fausto Maffini, Daniela Alterio, Maria Cossu Rocca, Giuseppe Petralia, Roberto Bruschini, Fausto Chiesa. (2010) Future challenges in head and neck cancer: From the bench to the bedside?. Critical Reviews in Oncology/Hematology
CrossRef128
Ly Do, Nisar Syed, Ajmel Puthawala, Samar Azawi, Richard Williams, Nayana Vora. (2010) Prognostic Significance of Bone or Cartilage Invasion of Locally Advanced Head and Neck Cancers. American Journal of Clinical Oncology 33:6, 591-594
CrossRef129
Jarrod B. Adkison, Derek R. McHaffie, Søren M. Bentzen, Rakesh R. Patel, Deepak Khuntia, Daniel G. Petereit, Theodore S. Hong, Wolfgang Tomé, Mark A. Ritter. (2010) Phase I Trial of Pelvic Nodal Dose Escalation with Hypofractionated IMRT for High-Risk Prostate Cancer. International Journal of Radiation Oncology*Biology*Physics
CrossRef130
Chun-Ta Liao, Chien-Yu Lin, Kang-Hsing Fan, Hung-Ming Wang, Shu-Hang Ng, Li-Yu Lee, Chuen Hsueh, I-How Chen, Shiang-Fu Huang, Chung-Jan Kang. (2010) Identification of a High-Risk Group Among Patients With Oral Cavity Squamous Cell Carcinoma and pT1–2N0 Disease. International Journal of Radiation OncologyBiologyPhysics
CrossRef131
Jonathan D. Schoenfeld, David J. Sher, Charles M. Norris Jr., Robert I. Haddad, Marshall R. Posner, Tracy A. Balboni, Roy B. Tishler. (2010) Salivary Gland Tumors Treated With Adjuvant Intensity-Modulated Radiotherapy With or Without Concurrent Chemotherapy. International Journal of Radiation OncologyBiologyPhysics
CrossRef132
Anthony Prince, Julio Aguirre-Ghizo, Eric Genden, Marshall Posner, Andrew Sikora. (2010) Head and Neck Squamous Cell Carcinoma: New Translational Therapies. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 77:6, 684-699
CrossRef133
Renee Penn, Elliot Abemayor, Vishad Nabili, Sunita Bhuta, Claudia Kirsch. (2010) Perineural invasion detected by high-field 3.0-T magnetic resonance imaging. American Journal of Otolaryngology 31:6, 482-484
CrossRef134
Kevin S. Choe, Joseph K. Salama, Kerstin M. Stenson, Elizabeth A. Blair, Mary Ellyn Witt, Ezra E.W. Cohen, Daniel J. Haraf, Everett E. Vokes. (2010) Adjuvant chemotherapy prior to postoperative concurrent chemoradiotherapy for locoregionally advanced head and neck cancer. Radiotherapy and Oncology 97:2, 318-321
CrossRef135
W. Jerjes, T. Upile, S. Akram, C. Hopper. (2010) The Surgical Palliation of Advanced Head and Neck Cancer using Photodynamic Therapy. Clinical Oncology 22:9, 785-791
CrossRef136
Chien-Yu Lin, Hung-Ming Wang, Chung-Jan Kang, Li-Yu Lee, Shiang-Fu Huang, Kang-Hsing Fan, Eric Yen-Chao Chen, I-How Chen, Chun-Ta Liao, Joseph Tung-Chieh Chang. (2010) Primary Tumor Site as a Predictor of Treatment Outcome for Definitive Radiotherapy of Advanced-Stage Oral Cavity Cancers. International Journal of Radiation Oncology*Biology*Physics 78:4, 1011-1019
CrossRef137
David J. Sher, Robert I. Haddad, Charles M. Norris, Marshall R. Posner, Lori J. Wirth, Laura A. Goguen, Donald Annino, Tracy Balboni, Aaron Allen, Roy B. Tishler. (2010) Efficacy and toxicity of reirradiation using intensity-modulated radiotherapy for recurrent or second primary head and neck cancer. Cancer 116:20, 4761-4768
CrossRef138
M. R. Posner. (2010) Integrating systemic agents into multimodality treatment of locally advanced head and neck cancer. Annals of Oncology 21:Supplement 7, vii246-vii251
CrossRef139
Hans Christiansen, Ralph M.W. Rödel, Christoph Matthias, Clemens F. Hess, Hendrik A. Wolff. (2010) In regards to Barkati et al. (Int J Radiat Oncol Biol Phys 2010;76:410–416). International Journal of Radiation Oncology*Biology*Physics 78:2, 639-640
CrossRef140
Niels M. Graafland, Hester H. van Boven, Erik van Werkhoven, Luc M.F. Moonen, Simon Horenblas. (2010) Prognostic Significance of Extranodal Extension in Patients With Pathological Node Positive Penile Carcinoma. The Journal of Urology 184:4, 1347-1353
CrossRef141
Takenori Ogawa, Kazumi Ogawa, Kiyoto Shiga, Toru Furukawa, Hiroki Nagase, Sho Hashimoto, Toshimitsu Kobayashi, Akira Horii. (2010) Upregulation of IGF2 is associated with an acquired resistance for cis-diamminedichloroplatinum in human head and neck squamous cell carcinoma. European Archives of Oto-Rhino-Laryngology 267:10, 1599-1606
CrossRef142
A.S. Ihloff, C. Petersen, M. Hoffmann, R. Knecht, S. Tribius. (2010) Human papilloma virus in locally advanced stage III/IV squamous cell cancer of the oropharynx and impact on choice of therapy. Oral Oncology 46:10, 705-711
CrossRef143
Mulokozi Lugakingira, Kristen Pytynia, Antonia Kolokythas, Michael Miloro. (2010) Primary Intraosseous Carcinoma of the Mandible: Case Report and Review of the Literature. Journal of Oral and Maxillofacial Surgery 68:10, 2623-2629
CrossRef144
C. A. Fischer, M. Kampmann, I. Zlobec, E. Green, L. Tornillo, A. Lugli, M. Wolfensberger, L. M. Terracciano. (2010) p16 expression in oropharyngeal cancer: its impact on staging and prognosis compared with the conventional clinical staging parameters. Annals of Oncology 21:10, 1961-1966
CrossRef145
Susan Furness, Anne-Marie Glenny, Helen V Worthington, Sue Pavitt, Richard Oliver, Jan E Clarkson, Michaelina Macluskey, Kelvin KW Chan, David I Conway, The CSROC Expert Panel, Susan Furness. 2010. Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy. .
CrossRef146
Gregory S. Weinstein, Harry Quon, Bert W. O'Malley, Grace G. Kim, Marc A. Cohen. (2010) Selective neck dissection and deintensified postoperative radiation and chemotherapy for oropharyngeal cancer: A subset analysis of the university of pennsylvania transoral robotic surgery trial. The Laryngoscope 120:9, 1749-1755
CrossRef147
Ibrahim O. Bello, Ylermi Soini, Tuula Salo. (2010) Prognostic evaluation of oral tongue cancer: Means, markers and perspectives (II). Oral Oncology 46:9, 636-643
CrossRef148
Emily Crozier, Baran D. Sumer. (2010) Head and Neck Cancer. Medical Clinics of North America 94:5, 1031-1046
CrossRef149
Christof Röösli, Gabriela Studer, Sandro J. Stoeckli. (2010) Salvage treatment for recurrent oropharyngeal squamous cell carcinoma. Head & Neck 32:8, 989-996
CrossRef150
Cheng-Hsien Wu, Tzu-Ying Wu, Chia-Chen Li, Man-Tin Lui, Kuo-Wei Chang, Shou-Yen Kao. (2010) Impact of Diabetes Mellitus on the Prognosis of Patients with Oral Squamous Cell Carcinoma: A Retrospective Cohort Study. Annals of Surgical Oncology 17:8, 2175-2183
CrossRef151
Johannes A. Langendijk, Alfio Ferlito, Robert P. Takes, Juan P. Rodrigo, Carl Suárez, Primo Strojan, Missak Haigentz, Alessandra Rinaldo. (2010) Postoperative strategies after primary surgery for squamous cell carcinoma of the head and neck. Oral Oncology 46:8, 577-585
CrossRef152
Harry Quon, Bert W. O’Malley, Gregory S. Weinstein. (2010) Transoral robotic surgery and a paradigm shift in the management of oropharyngeal squamous cell carcinoma. Journal of Robotic Surgery 4:2, 79-86
CrossRef153
Amy C. Hessel, Mauricio A. Moreno, Ehab Y. Hanna, Dianna B. Roberts, Jan S. Lewin, Adel K. El-Naggar, David I. Rosenthal, Randal S. Weber. (2010) Compliance with quality assurance measures in patients treated for early oral tongue cancer. Cancer 116:14, 3408-3416
CrossRef154
A. Paccagnella, M. G. Ghi, L. Loreggian, A. Buffoli, H. Koussis, C. A. Mione, A. Bonetti, F. Campostrini, G. Gardani, A. Ardizzoia, D. Dondi, M. Guaraldi, R. Cavallo, L. Tomio, A. Gava, . (2010) Concomitant chemoradiotherapy versus induction docetaxel, cisplatin and 5 fluorouracil (TPF) followed by concomitant chemoradiotherapy in locally advanced head and neck cancer: a phase II randomized study. Annals of Oncology 21:7, 1515-1522
CrossRef155
Eric M. Genden, Alfio Ferlito, Carl E. Silver, Robert P. Takes, Carlos Suárez, Randall P. Owen, Missak Haigentz, Sandro J. Stoeckli, Ashok R. Shaha, Alexander D. Rapidis, Juan Pablo Rodrigo, Alessandra Rinaldo. (2010) Contemporary management of cancer of the oral cavity. European Archives of Oto-Rhino-Laryngology 267:7, 1001-1017
CrossRef156
Dirk Rades, Stefanie Kronemann, Thekla Meyners, Steven E. Schild, Samer G. Hakim. (2010) Acute toxicity of three versus two courses of cisplatin for radiochemotherapy of locally advanced squamous cell carcinoma of the head and neck (SCCHN): A matched pair analysis. Oral Oncology 46:7, 549-552
CrossRef157
Kang-Hsing Fan, Hung-Ming Wang, Chung-Jan Kang, Li-Yu Lee, Shiang-Fu Huang, Chien-Yu Lin, Eric Yen-Chao Chen, I-How Chen, Chun-Ta Liao, Joseph Tung-Chieh Chang. (2010) Treatment Results of Postoperative Radiotherapy on Squamous Cell Carcinoma of the Oral Cavity: Coexistence of Multiple Minor Risk Factors Results in Higher Recurrence Rates. International Journal of Radiation Oncology*Biology*Physics 77:4, 1024-1029
CrossRef158
Iris Gluck, Felix Y. Feng, Teresa Lyden, Marc Haxer, Francis Worden, Douglas B. Chepeha, Avraham Eisbruch. (2010) Evaluating and Reporting Dysphagia in Trials of Chemoirradiation for Head-and-Neck Cancer. International Journal of Radiation Oncology*Biology*Physics 77:3, 727-733
CrossRef159
Jae-Yol Lim, Young Chang Lim, Se-Heon Kim, Jae Wook Kim, Ha Min Jeong, Eun Chang Choi. (2010) Predictive factors of isolated distant metastasis after primary definitive surgery without systemic treatment for head and neck squamous cell carcinoma. Oral Oncology 46:7, 504-508
CrossRef160
Levon Igidbashian, Bernard Fortin, Louis Guertin, Denis Soulières, Geneviève Coulombe, Manon Belair, Danielle Charpentier, Jean-Claude Tabet, Phuc Felix Nguyen-Tan. (2010) Outcome With Neck Dissection After Chemoradiation for N3 Head-and-Neck Squamous Cell Carcinoma. International Journal of Radiation Oncology*Biology*Physics 77:2, 414-420
CrossRef161
Scott Sklenicka, Stuart Gardiner, Eric J. Dierks, Bryce E. Potter, R. Bryan Bell. (2010) Survival Analysis and Risk Factors for Recurrence in Oral Squamous Cell Carcinoma: Does Surgical Salvage Affect Outcome?. Journal of Oral and Maxillofacial Surgery 68:6, 1270-1275
CrossRef162
Rafal Suwinski, Magdalena Jaworska, Barbara Nikiel, Wozniak Grzegorz, Magdalena Bankowska-Wozniak, Majewski Wojciech, Skladowski Krzysztof, Lange Dariusz. (2010) Predicting the Effect of Accelerated Fractionation in Postoperative Radiotherapy for Head and Neck Cancer Based on Molecular Marker Profiles: Data From a Randomized Clinical Trial. International Journal of Radiation Oncology*Biology*Physics 77:2, 438-446
CrossRef163
Nicholas Kalavrezos, Rishi Bhandari. (2010) Current trends and future perspectives in the surgical management of oral cancer. Oral Oncology 46:6, 429-432
CrossRef164
S. Jelic, I. Popov, V. H. Schartinger, G. M. Sprinzl. (2010) Head and neck cancer: a step forward. memo - Magazine of European Medical Oncology 3:2, 85-89
CrossRef165
Piotr Winczura, Jacek Jassem. (2010) Combined treatment with cytoprotective agents and radiotherapy. Cancer Treatment Reviews 36:3, 268-275
CrossRef166
Jacques Bernier, Lisa Licitra. (2010) Chemotherapy: Chemoradiation in head-and-neck cancer—are we any closer?. Nature Reviews Clinical Oncology 7:5, 247-249
CrossRef167
Matthias Kreppel, Martin Scheer, Uta Drebber, Lutz Ritter, Joachim E. Zöller. (2010) Impact of podoplanin expression in oral squamous cell carcinoma: clinical and histopathologic correlations. Virchows Archiv 456:5, 473-482
CrossRef168
V. Gregoire, J.- L. Lefebvre, L. Licitra, E. Felip, . (2010) Squamous cell carcinoma of the head and neck: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology 21:Supplement 5, v184-v186
CrossRef169
Harry Quon, Sue S. Yom, Madhur Kumar Garg, Joshua Lawson, Mark W. McDonald, John A. Ridge, Nabil Saba, Joseph Salama, Richard Smith, Anamaria Reyna Yeung, Jonathan J. Beitler. (2010) ACR Appropriateness Criteria®: Local–Regional Therapy for Resectable Oropharyngeal Squamous Cell Carcinomas. Current Problems in Cancer 34:3, 175-192
CrossRef170
Gilberto de Castro, Rodrigo SC Guindalini. (2010) Supportive care in head and neck oncology. Current Opinion in Oncology 22:3, 221-225
CrossRef171
Eugene N. Myers. (2010) Head and neck oncology – 2010, part I. Otolaryngologia Polska 64:3, 136-146
CrossRef172
Yungan Tao, Nicolas Daly-Schveitzer, Antoine Lusinchi, Jean Bourhis. (2010) Advances in radiotherapy of head and neck cancers. Current Opinion in Oncology 22:3, 194-199
CrossRef173
S. Marur, A. A. Forastiere. (2010) Update on role of chemotherapy in head and neck squamous cell cancer. Indian Journal of Surgical Oncology 1:2, 85-95
CrossRef174
Chun-Ta Liao, Shiang-Fu Huang, I-How Chen, Chung-Jan Kang, Chien-Yu Lin, Kang-Hsing Fan, Hung-Ming Wang, Shu-Hang Ng, Chuen Hsueh, Li-Yu Lee, Chung-Kan Tsao, Tzu-Chen Yen. (2010) Outcome Analysis of Patients with pN2 Oral Cavity Cancer. Annals of Surgical Oncology 17:4, 1118-1126
CrossRef175
Tomoko Nomura, Ryuji Murakami, Ryo Toya, Keiko Teshima, Aya Nakahara, Toshinori Hirai, Akimitsu Hiraki, Hideki Nakayama, Yoshihiro Yoshitake, Kazutoshi Ota, Takehisa Obayashi, Yasuyuki Yamashita, Natsuo Oya, Masanori Shinohara. (2010) Phase II Study of Preoperative Concurrent Chemoradiation Therapy With S-1 in Patients With T4 Oral Squamous Cell Carcinoma. International Journal of Radiation Oncology*Biology*Physics 76:5, 1347-1352
CrossRef176
R. M. Subramaniam, M. Truong, P. Peller, O. Sakai, G. Mercier. (2010) Fluorodeoxyglucose-Positron-Emission Tomography Imaging of Head and Neck Squamous Cell Cancer. American Journal of Neuroradiology 31:4, 598-604
CrossRef177
Richard J Wong, Jatin P Shah. (2010) The role of the head and neck surgeon in contemporary multidisciplinary treatment programs for advanced head and neck cancer. Current Opinion in Otolaryngology & Head and Neck Surgery 18:2, 79-82
CrossRef178
Monica Ramos, Sergi Benavente, Jordi Giralt. (2010) Management of squamous cell carcinoma of the head and neck: updated European treatment recommendations. Expert Review of Anticancer Therapy 10:3, 339-344
CrossRef179
E. P. M. Jansen, H. Boot, R. Dubbelman, M. Verheij, A. Cats. (2010) Postoperative chemoradiotherapy in gastric cancer--a phase I-II study of radiotherapy with dose escalation of weekly cisplatin and daily capecitabine chemotherapy. Annals of Oncology 21:3, 530-534
CrossRef180
Kyle E. Rusthoven, David Raben, John I. Song, Madeleine Kane, Taghrid A. Altoos, Changhu Chen. (2010) Survival and Patterns of Relapse in Patients With Oral Tongue Cancer. Journal of Oral and Maxillofacial Surgery 68:3, 584-589
CrossRef181
A. Hartley, P. Sanghera, J. Glaholm, H. Mehanna, C. McConkey, J. Fowler. (2010) Radiobiological Modelling of the Therapeutic Ratio for the Addition of Synchronous Chemotherapy to Radiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and Neck. Clinical Oncology 22:2, 125-130
CrossRef182
George H. Yoo, Geetha Subramanian, Waleed H. Ezzat, Ozlem E. Tulunay, Vivian R. Tran, Fulvio Lonardo, John F. Ensley, Harold Kim, Joshua Won, Timothy Stevens, Louis A. Zumstein, Ho-Sheng Lin. (2010) Intratumoral delivery of docetaxel enhances antitumor activity of Ad-p53 in murine head and neck cancer xenograft model. American Journal of Otolaryngology 31:2, 78-83
CrossRef183
Kumar Prabhash, V R Pai, Purvish M Parikh, Ameesh Vora, Kumar Prabhash. 2010. Postoperative chemoradiation for head and neck cancers. .
CrossRef184
K. Schwenzer-Zimmerer, K. Kansy, H.-F. Zeilhofer, A. Zippelius, F. Zimmermann. (2010) Adjuvante Therapie bei Kopf-Hals-Tumoren. Der MKG-Chirurg 3:1, 25-29
CrossRef185
Junichi Fukada, Naoyuki Shigematsu, Atsuya Takeda, Toshio Ohashi, Toshiki Tomita, Akihiro Shiotani, Etsuo Kunieda, Osamu Kawaguchi, Masato Fujii, Atsushi Kubo. (2010) Weekly Low-Dose Docetaxel–Based Chemoradiotherapy for Locally Advanced Oropharyngeal or Hypopharyngeal Carcinoma: A Retrospective, Single-Institution Study. International Journal of Radiation Oncology*Biology*Physics 76:2, 417-424
CrossRef186
Maroie Barkati, Bernard Fortin, Denis Soulières, Sébastien Clavel, Phillipe Després, Danielle Charpentier, Jean-Claude Tabet, Louis Guertin, Marie-Jo Olivier, Geneviève Coulombe, David Donath, Phuc Felix Nguyen-Tan. (2010) Concurrent Chemoradiation With Carboplatin–5-Fluorouracil Versus Cisplatin in Locally Advanced Oropharyngeal Cancers: Is More Always Better?. International Journal of Radiation Oncology*Biology*Physics 76:2, 410-416
CrossRef187
Anaëlle Duray, Stéphanie Demoulin, Pascale Hubert, Philippe Delvenne, Sven Saussez. (2010) Immune Suppression in Head and Neck Cancers: A Review. Clinical and Developmental Immunology 2010, 1-15
CrossRef188
Tsai-Ying Huang, Lee-Ping Hsu, Yu-Hsuan Wen, Tung-Tsun Huang, Yu-Fu Chou, Chia-Fong Lee, Miao-Chun Yang, Yi-Kuo Chang, Peir-Rong Chen. (2010) Predictors of locoregional recurrence in early stage oral cavity cancer with free surgical margins. Oral Oncology 46:1, 49-55
CrossRef189
Jeffrey S Tobias, Kathryn Monson, Nirmal Gupta, Hugh MacDougall, John Glaholm, Iain Hutchison, Latha Kadalayil, Allan Hackshaw. (2010) Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial. The Lancet Oncology 11:1, 66-74
CrossRef190
Takenori Ogawa, Toru Furukawa, Kiyoto Shiga, Sho Hashimoto, Kazumi Ogawa, Toshimitsu Kobayashi, Akira Horii. (2010) A cDNA microarray analysis identifies 52 genes associated with cis-diamminedichloroplatinum susceptibility in head and neck squamous cell carcinoma cell lines. European Archives of Oto-Rhino-Laryngology 267:1, 123-129
CrossRef191
A. S. Gokhale, B. T. McLaughlin, J. C. Flickinger, S. Beriwal, D. E. Heron, R. L. Ferris, J. Johnson, M. K. Gibson, A. Argiris, R. P. Smith. (2010) Clinical and dosimetric factors associated with a prolonged feeding tube requirement in patients treated with chemoradiotherapy (CRT) for head and neck cancers. Annals of Oncology 21:1, 145-151
CrossRef192
George H. Yoo, Zyed Kafri, John F. Ensley, Fulvio Lonardo, Harold Kim, Adam J. Folbe, Joshua Won, Timothy Stevens, Ho-Sheng Lin. (2010) XRP6258-induced gene expression patterns in head and neck cancer carcinoma. The LaryngoscopeNA-NA
CrossRef193
Toshiki Tomita, Yorihisa Imanishi, Hiroyuki Ozawa, Ryoichi Fujii, Seiji Shigetomi, Noboru Habu, Kuninori Otsuka, Kaoru Ogawa, Junichi Fukada, Naoyuki Shigematsu, Yasunao Kogashiwa, Kohichi Yamauchi, Naoyuki Kohno. (2010) Chemotherapy for head and neck cancer: Current status and problems in Japan. Toukeibu Gan 36:3, 273-277
CrossRef194
Primož Strojan, Alfio Ferlito, Johannes A. Langendijk, Carl E. Silver, David W. Eisele. (2010) Indications for radiotherapy after neck dissection. Head & Neckn/a-n/a
CrossRef195
Ziv Gil, Diane L. Carlson, Jay O. Boyle, Dennis H. Kraus, Jatin P. Shah, Ashok R. Shaha, Bhuvanesh Singh, Richard J. Wong, Snehal G. Patel. (2009) Lymph node density is a significant predictor of outcome in patients with oral cancer. Cancer 115:24, 5700-5710
CrossRef196
Shefali Agrawal, John M. Kane, Beverly A. Guadagnolo, William G. Kraybill, Matthew T. Ballo. (2009) The benefits of adjuvant radiation therapy after therapeutic lymphadenectomy for clinically advanced, high-risk, lymph node-metastatic melanoma. Cancer 115:24, 5836-5844
CrossRef197
MyChau T. Nguyen, Irim Y. Virk, Lita Chew, J. Lee Villano. (2009) Extended use dexamethasone-associated posterior reversible encephalopathy syndrome with cisplatin-based chemotherapy. Journal of Clinical Neuroscience 16:12, 1688-1690
CrossRef198
K Reid, C Hicks, S Herron-Marx, S Parmar. (2009) Effect of oral tumour size on quality of life judgements by health care professionals working with head and neck cancer patients: a pilot study. The Journal of Laryngology & Otology 123:12, 1352
CrossRef199
Minh Tam Truong, Gregory Grillone, Christine Tschoe, Lawrence Chin, Lisa Ann Kachnic, Scharukh Jalisi. (2009) Emerging applications of stereotactic radiotherapy in head and neck cancer. Neurosurgical FOCUS 27:6, E11
CrossRef200
Byoung Chul Cho, Ki Chang Keum, Sang Joon Shin, Hye Jin Choi, Young Joo Lee, Se Hun Kim, Eun Chang Choi, Joo Hang Kim. (2009) Weekly docetaxel in patients with platinum-refractory metastatic or recurrent squamous cell carcinoma of the head and neck. Cancer Chemotherapy and Pharmacology 65:1, 27-32
CrossRef201
Christof Hofele, Kolja Freier, Oliver C. Thiele, Uwe Haberkorn, Inga Buchmann. (2009) High 2-[18F]fluoro-2-deoxy-d-glucose (18FDG) uptake measured by positron emission tomography is associated with reduced overall survival in patients with oral squamous cell carcinoma. Oral Oncology 45:11, 963-967
CrossRef202
Chun-Ta Liao, Joseph Tung-Chieh Chang, Hung-Ming Wang, Shu-Hang Ng, Shiang-Fu Huang, I-How Chen, Chuen Hsueh, Li-Yu Lee, Chih-Hung Lin, Ann-Joy Cheng, Tzu-Chen Yen. (2009) Preoperative [18F]-fluorodeoxyglucose positron emission tomography standardized uptake value of neck lymph nodes may aid in selecting patients with oral cavity squamous cell carcinoma for salvage therapy after relapse. European Journal of Nuclear Medicine and Molecular Imaging 36:11, 1783-1793
CrossRef203
Christine G. Gourin, Jonas T. Johnson. (2009) A contemporary review of indications for primary surgical care of patients with squamous cell carcinoma of the head and neck. The Laryngoscope 119:11, 2124-2134
CrossRef204
Joseph K. Salama, Robert I. Haddad, Merril S. Kies, Paul M. Busse, Lei Dong, David M. Brizel, Avraham Eisbruch, Roy B. Tishler, Andy M. Trotti, Adam S. Garden. (2009) Clinical Practice Guidance for Radiotherapy Planning After Induction Chemotherapy in Locoregionally Advanced Head-and-Neck Cancer. International Journal of Radiation Oncology*Biology*Physics 75:3, 725-733
CrossRef205
Johnny Kao, Ha Linh Vu, Eric M. Genden, Bharat Mocherla, Eunice E. Park, Stuart Packer, Peter M. Som, Lale Kostakoglu. (2009) The diagnostic and prognostic utility of positron emission tomography/computed tomography-based follow-up after radiotherapy for head and neck cancer. Cancer 115:19, 4586-4594
CrossRef206
Brian C. Boulmay, Bhishamjit S. Chera, Christopher G. Morris, Jessica Kirwan, Charles E. Riggs, Michael Lawson, William M. Mendenhall. (2009) Definitive Altered Fractionation Radiotherapy and Concomitant Weekly Cisplatin for Locally Advanced Head and Neck Cancer. American Journal of Clinical Oncology 32:5, 488-491
CrossRef207
Ly Do, Ajmel Puthawala, Nisar Syed. (2009) Interstitial brachytherapy as boost for locally advanced T4 head and neck cancer. Brachytherapy 8:4, 385-391
CrossRef208
Diana Steinmann, Bettina Cerny, Johann Hinrich Karstens, Michael Bremer. (2009) Chemoradiotherapy with Weekly Cisplatin 40 mg/m2 in 103 Head-and-Neck Cancer Patients. Strahlentherapie und Onkologie 185:10, 682-688
CrossRef209
Matthew M. Hanasono, Michael T. Friel, Christopher Klem, Patrick W. Hsu, Geoffrey L. Robb, Randal S. Weber, Dianna B. Roberts, David W. Chang. (2009) Impact of reconstructive microsurgery in patients with advanced oral cavity cancers. Head & Neck 31:10, 1289-1296
CrossRef210
Ly Do, Ajmel Puthawala, Nisar Syed, Samar Azawi, Richard Williams, Nayana Vora. (2009) Treatment Outcomes of T4 Locally Advanced Head and Neck Cancers With Soft Tissue Invasion or Bone and Cartilage Invasion. American Journal of Clinical Oncology 32:5, 477-482
CrossRef211
Branislav Jeremić, Biljana Miličić. (2009) Pretreatment Prognostic Factors Influencing Distant Metastasis-Free Survival in Locally Advanced Squamous Cell Carcinoma of the Head and Neck Treated With Radiation Therapy With or Without Concurrent Chemotherapy. American Journal of Clinical Oncology 32:5, 483-487
CrossRef212
Francesco Caponigro, Francesco Longo, Francesco Perri, Franco Ionna. (2009) Docetaxel in the management of head and neck cancer. Anti-Cancer Drugs 20:8, 639-645
CrossRef213
O. Matzinger, A. Zouhair, R.O. Mirimanoff, M. Ozsahin. (2009) Radiochemotherapy in Locally Advanced Squamous Cell Carcinomas of the Head and Neck. Clinical Oncology 21:7, 525-531
CrossRef214
(2009) Carcinome épidermoïde cutané (carcinome spinocellulaire) : Recommandations de pratique clinique pour la prise en charge diagnostique et thérapeutique Argumentaire - Mai 2009. Annales de Dermatologie et de Vénéréologie 136, S189-S242
CrossRef215
Clemens Klug, Dominik Berzaczy, Martin Voracek, Christina Nell, Oliver Ploder, Werner Millesi, Rolf Ewers. (2009) Preoperative radiochemotherapy in the treatment of advanced oral cancer: Outcome of 276 patients. Journal of Cranio-Maxillofacial Surgery 37:6, 344-347
CrossRef216
Cesar A. Perez, Chancellor E. Donald, Luis E. Raez, Edgardo S. Santos. (2009) Epidermal growth factor receptor pathway as therapeutic development in head and neck cancers: present and future. Oncology Reviews 3:3, 137-148
CrossRef217
Lilie L. Lin, Stephen M. Hahn. (2009) Combined Modality Therapy in the Elderly Population. Current Treatment Options in Oncology 10:3-4, 195-204
CrossRef218
Joseph I. Clark, Robert M. Eisner, Craig Hofmeister, John Norton, Sachdev Thomas, Abdul Choudhury, Guy Petruzzelli, Deanne Lathers, M Rita I. Young, Ann Lau, Bahman Emami. (2009) Phase I Adjuvant Radiation With Docetaxel in High-Risk Head and Neck Cancer. American Journal of Clinical Oncology 32:4, 396-400
CrossRef219
Aron Popovtzer, Iris Gluck, Douglas B. Chepeha, Theodoros N. Teknos, Jeffrey S. Moyer, Mark E. Prince, Carol R. Bradford, Avraham Eisbruch. (2009) The Pattern of Failure After Reirradiation of Recurrent Squamous Cell Head and Neck Cancer: Implications for Defining the Targets. International Journal of Radiation Oncology*Biology*Physics 74:5, 1342-1347
CrossRef220
Michael B Prystowsky, Alfred Adomako, Richard V Smith, Nicole Kawachi, Wendy McKimpson, Peter Atadja, Quan Chen, Nicolas F Schlecht, Joanna L Parish, Geoffrey Childs, Thomas J Belbin. (2009) The histone deacetylase inhibitor LBH589 inhibits expression of mitotic genes causing G2/M arrest and cell death in head and neck squamous cell carcinoma cell lines. The Journal of Pathology 218:4, 467-477
CrossRef221
Thomas Mücke, Stefan Wagenpfeil, Marco R. Kesting, Frank Hölzle, Klaus-Dietrich Wolff. (2009) Recurrence interval affects survival after local relapse of oral cancer. Oral Oncology 45:8, 687-691
CrossRef222
Roshan Prabhu, Russell W. Hinerman, Daniel J. Indelicato, Christopher G. Morris, John W. Werning, Mikhail Vaysberg, Robert J. Amdur, Jessica Kirwan, William M. Mendenhall. (2009) Squamous Cell Carcinoma of the External Auditory Canal. American Journal of Clinical Oncology 32:4, 401-404
CrossRef223
Hendrik Andreas Wolff, Tobias Overbeck, Ralph M. Roedel, Robert M. Hermann, Markus K. A. Herrmann, Tereza Kertesz, Hilke Vorwerk, Andrea Hille, Christoph Matthias, Clemens F. Hess, Hans Christiansen. (2009) Toxicity of daily low dose cisplatin in radiochemotherapy for locally advanced head and neck cancer. Journal of Cancer Research and Clinical Oncology 135:7, 961-967
CrossRef224
Farzan Siddiqui, Mehul Patel, Mumtaz Khan, Scott McLean, Jadranka Dragovic, Jian-Yue Jin, Benjamin Movsas, Samuel Ryu. (2009) Stereotactic Body Radiation Therapy for Primary, Recurrent, and Metastatic Tumors in the Head-and-Neck Region. International Journal of Radiation Oncology*Biology*Physics 74:4, 1047-1053
CrossRef225
Dániel Sinkó, Tímea Klinkó, Csaba Weisz, Csaba Nemeskéri, Attila Fekésházy, Viktória Tóth, Zoltán Tóth, Árpád Mayer. (2009) PET/CT alapú besugárzástervezéssel szerzett tapasztalatok fej-nyaki tumorokban. Orvosi Hetilap 150:30, 1403-1406
CrossRef226
Chun-Ta Liao, Joseph Tung-Chieh Chang, Hung-Ming Wang, Shu-Hang Ng, Chuen Hsueh, Li-Yu Lee, Chih-Hung Lin, I-How Chen, Shiang-Fu Huang, Ann-Joy Cheng, Tzu-Chen Yen. (2009) Preoperative [18F]Fluorodeoxyglucose Positron Emission Tomography Standardized Uptake Value of Neck Lymph Nodes Predicts Neck Cancer Control and Survival Rates in Patients With Oral Cavity Squamous Cell Carcinoma and Pathologically Positive Lymph Nodes. International Journal of Radiation Oncology*Biology*Physics 74:4, 1054-1061
CrossRef227
Naoki Kunii, Shigetoshi Horiguchi, Shinichiro Motohashi, Heizaburo Yamamoto, Naoyuki Ueno, Seiji Yamamoto, Daiju Sakurai, Masaru Taniguchi, Toshinori Nakayama, Yoshitaka Okamoto. (2009) Combination therapy of in vitro -expanded natural killer T cells and α-galactosylceramide-pulsed antigen-presenting cells in patients with recurrent head and neck carcinoma. Cancer Science 100:6, 1092-1098
CrossRef228
Wen-Cheng Chen, Tzer-Zen Hwang, Wen-Hung Wang, Chang-Hsien Lu, Chih-Cheng Chen, Chien-Ming Chen, Hsu-Huei Weng, Chia-Hsuan Lai, Miao-Fen Chen. (2009) Comparison between conventional and intensity-modulated post-operative radiotherapy for stage III and IV oral cavity cancer in terms of treatment results and toxicity. Oral Oncology 45:6, 505-510
CrossRef229
Giovanni Franchin, Emilio Minatel, Doriano Politi, Carlo Gobitti, Renato Talamini, Emanuela Vaccher, Maria Gabriella Savignano, Marco Trovo, Sandro Sulfaro, Luigi Barzan. (2009) Postoperative reduced dose of cisplatin concomitant with radiation therapy in high- risk head and neck squamous cell carcinoma. Cancer 115:11, 2464-2471
CrossRef230
Nicholas Pavlidis, George Pentheroudakis, George Plataniotis. (2009) Cervical lymph node metastases of squamous cell carcinoma from an unknown primary site: a favourable prognosis subset of patients with CUP. Clinical and Translational Oncology 11:6, 340-348
CrossRef231
Oliver Driemel, Tobias Ettl, Oliver Kölbl, Torsten E. Reichert, Bernd V. Dresp, Jürgen Reuther, Hans Pistner. (2009) Outcome and Histopathologic Regression in Oral Squamous Cell Carcinoma after Preoperative Radiochemotherapy. Strahlentherapie und Onkologie 185:5, 296-302
CrossRef232
Berrin Pehlivan, Francois Luthi, Oscar Matzinger, Michael Betz, Daniela Dragusanu, Shelley Bulling, Luc Bron, Philippe Pasche, Walter Seelentag, René O. Mirimanoff, Abderrahim Zouhair, Mahmut Ozsahin. (2009) Feasibility and Efficacy of Accelerated Weekly Concomitant Boost Postoperative Radiation Therapy Combined with Concomitant Chemotherapy in Patients with Locally Advanced Head and Neck Cancer. Annals of Surgical Oncology 16:5, 1337-1343
CrossRef233
R. Knecht. (2009) Strahlen-, Chemo- und Targettherapie von Kopf-Hals-Karzinomen. HNO 57:5, 436-445
CrossRef234
Arno Olthoff, Andreas Ewen, Hendrik Andreas Wolff, Robert Michael Hermann, Hilke Vorwerk, Andrea Hille, Ralph Rödel, Clemens F. Hess, Wolfgang Steiner, Olivier Pradier, Hans Christiansen. (2009) Organ Function and Quality of Life after Transoral Laser Microsurgery and Adjuvant Radiotherapy for Locally Advanced Laryngeal Cancer. Strahlentherapie und Onkologie 185:5, 303-309
CrossRef235
R.D. Farhadieh, C.G.G. Rees, J.L. Yang, A. Salardini, P. Russell, R. Smee. (2009) Radiotherapy in Larynx Squamous Cell Carcinoma is not Associated with an Increased Diagnosis of Second Primary Tumours. Clinical Oncology 21:4, 315-319
CrossRef236
Berrin Pehlivan, Abderrahim Zouhair, François Luthi, Luc Bron, Philippe Pasche, Daniela Dragusanu, David Azria, Oscar Matzinger, René O. Mirimanoff, Mahmut Ozsahin. (2009) Decrease in Hemoglobin Levels Following Surgery Influences the Outcome in Head and Neck Cancer Patients Treated with Accelerated Postoperative Radiotherapy. Annals of Surgical Oncology 16:5, 1331-1336
CrossRef237
Nabil F Saba, Fadlo R Khuri. (2009) Optimizing systemic therapy in squamous cell carcinoma of the head and neck with a focus on targeted agents. Current Opinion in Oncology 21:3, 232-237
CrossRef238
L. Licitra, E. Felip, . (2009) Squamous cell carcinoma of the head and neck: ESMO Clinical Recommendations for diagnosis, treatment and follow-up. Annals of Oncology 20:Supplement 4, iv121-iv122
CrossRef239
John M. Watkins, Keisuke S. Shirai, Amy E. Wahlquist, Robert K. Stuart, Uzair B. Chaudhary, Elizabeth Garrett-Mayer, Terry A. Day, M. Boyd Gillespie, Anand K. Sharma. (2009) Toxicity and survival outcomes of hyperfractionated split-course reirradiation and daily concurrent chemotherapy in locoregionally recurrent, previously irradiated head and neck cancers. Head & Neck 31:4, 493-502
CrossRef240
Stefan Michiels, Aurélie Le Maître, Marc Buyse, Tomasz Burzykowski, Emilie Maillard, Jan Bogaerts, Jan B Vermorken, Wilfried Budach, Thomas F Pajak, Kian K Ang, Jean Bourhis, Jean-Pierre Pignon. (2009) Surrogate endpoints for overall survival in locally advanced head and neck cancer: meta-analyses of individual patient data. The Lancet Oncology 10:4, 341-350
CrossRef241
Pol M. Specenier, Jan B. Vermorken. (2009) Current concepts for the management of head and neck cancer: Chemotherapy. Oral Oncology 45:4-5, 409-415
CrossRef242
Branislav Jeremić, Biljana Miličić. (2009) Pretreatment Prognostic Factors of Survival in Patients With Locally Advanced Nonmetastatic Squamous Cell Carcinoma of the Head and Neck Treated With Radiation Therapy With or Without Concurrent Chemotherapy. American Journal of Clinical Oncology 32:2, 163-168
CrossRef243
Renaud Mazeron, Yungan Tao, Antoine Lusinchi, Jean Bourhis. (2009) Current concepts of management in radiotherapy for head and neck squamous-cell cancer. Oral Oncology 45:4-5, 402-408
CrossRef244
Ajay Tejwani, Shenhong Wu, Yuxia Jia, Mark Agulnik, Laura Millender, Mario E. Lacouture. (2009) Increased risk of high-grade dermatologic toxicities with radiation plus epidermal growth factor receptor inhibitor therapy. Cancer 115:6, 1286-1299
CrossRef245
K. Bénézery, J. Thariat, C. Ortholan. (2009) La radiochimiothérapie dans les carcinomes épidermoïdes des voies aérodigestives supérieures. Oncologie 11:3, 140-146
CrossRef246
David Katz, Emma Ito, Fei-Fei Liu. (2009) On the Path to Seeking Novel Radiosensitizers. International Journal of Radiation Oncology*Biology*Physics 73:4, 988-996
CrossRef247
Ryan J Burri, Nancy Y Lee. (2009) Concurrent chemotherapy and radiotherapy for head and neck cancer. Expert Review of Anticancer Therapy 9:3, 293-302
CrossRef248
C Ko, D Citrin. (2009) Radiotherapy for the management of locally advanced squamous cell carcinoma of the head and neck. Oral Diseases 15:2, 121-132
CrossRef249
Miriam N. Lango, Genevieve A. Andrews, Sidrah Ahmad, Steven Feigenberg, Madalina Tuluc, John Gaughan, John A. Ridge. (2009) Postradiotherapy neck dissection for head and neck squamous cell carcinoma: Pattern of pathologic residual carcinoma and prognosis. Head & Neck 31:3, 328-337
CrossRef250
Daniel R. Gomez, Joanne E. Zhung, Jennifer Gomez, Kelvin Chan, Abraham J. Wu, Suzanne L. Wolden, David G. Pfister, Ashok Shaha, Jatin P. Shah, Dennis H. Kraus, Richard J. Wong, Nancy Y. Lee. (2009) Intensity-Modulated Radiotherapy in Postoperative Treatment of Oral Cavity Cancers. International Journal of Radiation Oncology*Biology*Physics 73:4, 1096-1103
CrossRef251
Nongnit Laytragoon-Lewin, Hasan Ustun, Juan Castro, Signe Friesland, Mehran Ghaderi, Jan Lundgren, Ingela Turesson, Freddi Lewin. (2009) In vitro effect of radiation, antibody to epidermal growth factor receptor and Docetaxel in human head and neck squamous carcinoma cells with mutant P53 and over-expressed EGFR. Journal of Cancer Research and Clinical Oncology 135:2, 203-209
CrossRef252
Miriam N. Lango. (2009) Multimodal Treatment for Head and Neck Cancer. Surgical Clinics of North America 89:1, 43-52
CrossRef253
Bronwyn King, June Corry. (2009) Pathology reporting in head and neck cancer-Snapshot of current status. Head & Neck 31:2, 227-231
CrossRef254
Voichita Bar Ad. (2009) Response to the comments on “Management of clinically negative neck for the patients with head and neck squamous cell carcinomas in the modern era”. Oral Oncology 45:2, 193
CrossRef255
Johannes A. Langendijk, Patricia Doornaert, Derek H.F. Rietveld, Irma M. Verdonck-de Leeuw, C. René Leemans, Ben J. Slotman. (2009) A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer. Radiotherapy and Oncology 90:2, 189-195
CrossRef256
Umamaheswar Duvvuri, Jeffrey N. Myers. (2009) Contemporary Management of Oropharyngeal Cancer. Current Problems in Surgery 46:2, 119-184
CrossRef257
Wai Lup Wong, Chris Nutting, Janet Dunn, Sheila Fisher, Ken MacLennan, Chris MacCabe, Hisham Mehanna. (2009) Advanced head and neck cancer: is there a role for fluorodeoxyglucose PET/computed tomography?. Nuclear Medicine Communications 30:1, 2-4
CrossRef258
Takahito Kondo, Kazuhiro Nakamura, Kiyoaki Tsukahara, Gou Hasegawa, Masaaki Shimizu, Tomoyuki Yoshida, Mamoru Suzuki. (2009) Safety of Postoperative Chemoradiotherapy with Cisplatin Infusion for High-risk Patients with Locally Advanced Head and Neck Carcinoma. Nihon Kikan Shokudoka Gakkai Kaiho 60:6, 464-469
CrossRef259
Anne M. Traynor, Gregory M. Richards, Gregory K. Hartig, Deepak Khuntia, James F. Cleary, Peggy A. Wiederholt, Søren M. Bentzen, Paul M. Harari. (2009) Comprehensive IMRT plus weekly cisplatin for advanced head and neck cancer: The University of Wisconsin experience. Head & NeckNA-NA
CrossRef260
Chun-Ta Liao, Shiang-Fu Huang, I-How Chen, Joseph Tung-Chieh Chang, Hung-Ming Wang, Shu-Hang Ng, Chuen Hsueh, Li-Yu Lee, Chih-Hung Lin, Ann-Joy Cheng, Tzu-Chen Yen. (2009) Risk Stratification of Patients with Oral Cavity Squamous Cell Carcinoma and Contralateral Neck Recurrence Following Radical Surgery. Annals of Surgical Oncology 16:1, 159-170
CrossRef261
(2009) JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY 19:1, 1-4
CrossRef262
Steven B. Cannady, Walter T. Lee, Joseph Scharpf, Robert R. Lorenz, Benjamin G. Wood, Marshall Strome, Pierre Lavertu, Ramon M. Esclamado, Jerrold P. Saxton, David J. Adelstein. (2009) Extent of neck dissection required after concurrent chemoradiation for stage IV head and neck squamous cell carcinoma. Head & NeckNA-NA
CrossRef263
ORAZAKHMET K. KURPESHEV, VALENTINA V. OSTAPENKO, YURI S. MARDYNSKY, NIKOLAI A. CHUSHKIN. (2009) Retrospective Analysis of Therapy for Locally Advanced Oral Cancer : Radiotherapy Alone and Thermoradiotherapy. Thermal Medicine 25:3, 59-70
CrossRef264
Kwok Hung Yu, Simon C. H. Yu, Edwin P. Hui, Michael K. M. Kam, Alexander C. Vlantis, Edmund Yuen, Anthony T. C. Chan. (2009) Accelerated fractionation radiotherapy and late intensification with 2 intra-arterial cisplatin infusions for locally advanced head and neck squamous cell carcinoma. Head & NeckNA-NA
CrossRef265
Xiaoying Yin, Hong Zhang, Karen Lundgren, Lynn Wilson, Francis Burrows, Carol G. Shores. (2009) BIIB021, a novel HSP90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy. International Journal of CancerNA-NA
CrossRef266
Sameer K. Nath, Daniel R. Simpson, Brent S. Rose, Ajay P. Sandhu. (2009) Recent Advances in Image-Guided Radiotherapy for Head and Neck Carcinoma. Journal of Oncology 2009, 1-10
CrossRef267
Missak Haigentz. 2009. Chemotherapy in Head and Neck Cancer. , 181-188.
CrossRef268
Gokcen Yildirim, William H. Morrison, David I. Rosenthal, Erich M. Sturgis, Vassiliki A. Papadimitrakopoulou, David L. Schwartz, Adam S. Garden. (2009) Outcomes of patients with tonsillar carcinoma treated with post-tonsillectomy radiation therapy. Head & NeckNA-NA
CrossRef269
Jacques Bernier. (2009) Current State-of-the-Art for Concurrent Chemoradiation. Seminars in Radiation Oncology 19:1, 3-10
CrossRef270
Rafael Martínez-Monge, Alfonso Gómez-Iturriaga, Mauricio Cambeiro, Cristina Garrán, Néstor Montesdeoca, José Javier Aristu, Juan Alcalde. (2009) Phase I–II trial of perioperative high-dose-rate brachytherapy in oral cavity and oropharyngeal cancer. Brachytherapy 8:1, 26-33
CrossRef271
David M. Brizel, Everett E. Vokes. (2009) Induction Chemotherapy: To Use or Not to Use? That Is the Question. Seminars in Radiation Oncology 19:1, 11-16
CrossRef272
David J. Adelstein, James Moon, Ehab Hanna, P. G. Shankar Giri, Glenn M. Mills, Gregory T. Wolf, Susan G. Urba. (2009) Docetaxel, cisplatin, and fluorouracil induction chemotherapy followed by accelerated fractionation/concomitant boost radiation and concurrent cisplatin in patients with advanced squamous cell head and neck cancer: A Southwest Oncology Group phase II trial (S0216). Head & NeckNA-NA
CrossRef273
James S. Brown, Richard J. Shaw, Simon N. Rogers, Derek Lowe. (2008) Re Kessler P et al. Neoadjuvant and adjuvant therapy in patients with oral squamous cell carcinoma. Long-term survival in a prospective, non-randomized study. Br J Oral Maxillofac Surg 2008; 46: 1-5. British Journal of Oral and Maxillofacial Surgery 46:8, 697
CrossRef274
Jacques Bernier. (2008) Incorporation of Molecularly Targeted Agents in the Primary Treatment of Squamous Cell Carcinomas of the Head and Neck. Hematology/Oncology Clinics of North America 22:6, 1193-1208
CrossRef275
Gregory J. Kubicek, Mitchell Machtay. (2008) New Advances in High-Technology Radiotherapy for Head and Neck Cancer. Hematology/Oncology Clinics of North America 22:6, 1165-1180
CrossRef276
Rajeev Sharan, Subramania Iyer, Shilpa S. Chatni, Jacob Samuel, Karimassery R. Sundaram, Richard F. Cohen, Keechilat Pavithran, Moni Abraham Kuriakose. (2008) Increased plate and osteosynthesis related complications associated with postoperative concurrent chemoradiotherapy in oral cancer. Head & Neck 30:11, 1422-1430
CrossRef277
Russell W. Hinerman, Daniel J. Indelicato, Robert J. Amdur, Christopher G. Morris, John W. Werning, Mikhail Vaysberg, Jessica Kirwan, William M. Mendenhall. (2008) Cutaneous Squamous Cell Carcinoma Metastatic to Parotid-Area Lymph Nodes. The Laryngoscope 118:11, 1989-1996
CrossRef278
Edgardo S Santos, Cesar Perez, Chancellor E Donald, Luis E Raez. (2008) Targeting important pathways in head and neck cancer: from the bench to the clinic. Expert Review of Anticancer Therapy 8:11, 1819-1835
CrossRef279
Kyle E. Rusthoven, David Raben, Changhu Chen. (2008) Improved Survival in Patients With Stage III-IV Head and Neck Cancer Treated With Radiotherapy as Primary Local Treatment Modality. International Journal of Radiation Oncology*Biology*Physics 72:2, 343-350
CrossRef280
Neil D. Gross, Snehal G. Patel, Andre L. Carvalho, Pen-Yuan Chu, Luis P. Kowalski, Jay O. Boyle, Jatin P. Shah, Michael W. Kattan. (2008) Nomogram for deciding adjuvant treatment after surgery for oral cavity squamous cell carcinoma. Head & Neck 30:10, 1352-1360
CrossRef281
Deepak Kademani, R. Bryan Bell, Brian L. Schmidt, Remy Blanchaert, Rui Fernandes, Paul Lambert, W. Mark Tucker. (2008) Oral and Maxillofacial Surgeons Treating Oral Cancer: A Preliminary Report From the American Association of Oral and Maxillofacial Surgeons Task Force on Oral Cancer. Journal of Oral and Maxillofacial Surgery 66:10, 2151-2157
CrossRef282
SV Porceddu, M Sidhom, M Foote, E Burmeister, A Stoneley, B El Hawwari, C Milross, L Kenny, M Poulsen, WB Coman. (2008) Predicting regional control based on pretreatment nodal size in squamous cell carcinoma of the head and neck treated with chemoradiotherapy: A clinican’s guide. Journal of Medical Imaging and Radiation Oncology 52:5, 491-496
CrossRef283
Fadime Can Akman, Nihal Dag, Ozlem Uruk Ataman, Cenk Ecevit, Ahmet Omer Ikiz, Isin Arslan, Sulen Sarıoglu, Emel Ada, Munir Kinay, . (2008) The impact of treatment center on the outcome of patients with laryngeal cancer treated with surgery and radiotherapy. European Archives of Oto-Rhino-Laryngology 265:10, 1245-1255
CrossRef284
David M. Cognetti, Randal S. Weber, Stephen Y. Lai. (2008) Head and neck cancer. Cancer 113:S7, 1911-1932
CrossRef285
Haddad, Robert I., Shin, Dong M., . (2008) Recent Advances in Head and Neck Cancer. New England Journal of Medicine 359:11, 1143-1154
Full Text286
André Fortin, Richard Caouette, Chang Shu Wang, Éric Vigneault. (2008) A Comparison of Treatment Outcomes by Radiochemotherapy and Postoperative Radiotherapy in Locally Advanced Squamous Cell Carcinomas of Head and Neck. American Journal of Clinical Oncology 31:4, 379-383
CrossRef287
Dimitrios Nikolarakos, R. Bryan Bell. (2008) Management of the Node-Positive Neck in Oral Cancer. Oral and Maxillofacial Surgery Clinics of North America 20:3, 499-511
CrossRef288
Boris Hristov, Gopal K. Bajaj. (2008) Radiotherapeutic Management of Laryngeal Carcinoma. Otolaryngologic Clinics of North America 41:4, 715-740
CrossRef289
Adam S. Garden, Jonathan Harris, Andy Trotti, Christopher U. Jones, Luis Carrascosa, Jonathan D. Cheng, Sharon S. Spencer, Arlene Forastiere, Randal S. Weber, K. Kian Ang. (2008) Long-Term Results of Concomitant Boost Radiation Plus Concurrent Cisplatin for Advanced Head and Neck Carcinomas: A Phase II Trial of the Radiation Therapy Oncology Group (RTOG 99-14). International Journal of Radiation Oncology*Biology*Physics 71:5, 1351-1355
CrossRef290
Allen Cheng, Brian L. Schmidt. (2008) Management of the N0 Neck in Oral Squamous Cell Carcinoma. Oral and Maxillofacial Surgery Clinics of North America 20:3, 477-497
CrossRef291
A. Sendler, D. Strumberg, A. Tannapfel. (2008) Metastasen eines unbekannten Primärtumors. Der Chirurg 79:7, 689-696
CrossRef292
Arlene A. Forastiere. (2008) Chemotherapy in the treatment of locally advanced head and neck cancer. Journal of Surgical Oncology 97:8, 701-707
CrossRef293
Corey J. Langer. (2008) Targeted therapy in head and neck cancer. Cancer 112:12, 2635-2645
CrossRef294
Laura Marucci, Barbara Pichi, Giuseppe Iaccarino, Paolo Ruscito, Giuseppe Spriano, Giorgio Arcangeli. (2008) Intraoperative radiation therapy as an “early boost” in locally advanced head and neck cancer: Preliminary results of a feasibility study. Head & Neck 30:6, 701-708
CrossRef295
Johnny Kao, Amir Lavaf, Marita S. Teng, Delphine Huang, Eric M. Genden. (2008) Adjuvant Radiotherapy and Survival for Patients With Node-Positive Head and Neck Cancer: An Analysis by Primary Site and Nodal Stage. International Journal of Radiation Oncology*Biology*Physics 71:2, 362-370
CrossRef296
David J. Adelstein, Cristina P. Rodriguez. (2008) Current and Emerging Standards of Concomitant Chemoradiotherapy. Seminars in Oncology 35:3, 211-220
CrossRef297
Branislav Jeremić, Biljana Miličić. (2008) Pretreatment Prognostic Factors of Local Recurrence-Free Survival in Locally Advanced Squamous Cell Carcinoma of the Head and Neck Treated With Radiation Therapy With or Without Concurrent Chemotherapy. American Journal of Clinical Oncology 31:3, 213-218
CrossRef298
C. Simon, P.K. Plinkert. (2008) Multimodale Therapiestrategien bei der Behandlung von Kopf- und Halskarzinomen. HNO 56:6, 575-584
CrossRef299
Joseph K. Salama, Everett E. Vokes. (2008) Concurrent Chemotherapy and Re-irradiation for Locoregionally Recurrent Head and Neck Cancer. Seminars in Oncology 35:3, 251-261
CrossRef300
Marshall Posner, Jan B. Vermorken. (2008) Induction Therapy in the Modern Era of Combined-Modality Therapy for Locally Advanced Head and Neck Cancer. Seminars in Oncology 35:3, 221-228
CrossRef301
B. R. Knab, J. K. Salama, A. Solanki, K. M. Stenson, E. E. Cohen, M. E. Witt, D. J. Haraf, E. E. Vokes. (2008) Functional organ preservation with definitive chemoradiotherapy for T4 laryngeal squamous cell carcinoma. Annals of Oncology 19:9, 1650-1654
CrossRef302
Séverine Racadot, Mariette Mercier, Sophie Dussart, Bernadette Dessard-Diana, René-Jean Bensadoun, Michel Martin, Emmanuelle Malaurie, Véronique Favrel, Martin Housset, Catherine Durdux, Catherine Journel, Gilles Calais, Jocelyne Huet, Gérard Pillet, Christophe Hennequin, Elias Haddad, Christian Diana, Brigitte Blaska-Jaulerry, Michel Henry-Amar, Pierre Géhanno, François Baillet, Jean-Jacques Mazeron. (2008) Randomized clinical trial of post-operative radiotherapy versus concomitant carboplatin and radiotherapy for head and neck cancers with lymph node involvement. Radiotherapy and Oncology 87:2, 164-172
CrossRef303
Dena J. Fischer, Gary D. Klasser, Joel B. Epstein. (2008) Cancer and Orofacial Pain. Oral and Maxillofacial Surgery Clinics of North America 20:2, 287-301
CrossRef304
Kyle Rusthoven, Changhu Chen, David Raben, Brian Kavanagh. (2008) Use of External Beam Radiotherapy Is Associated With Reduced Incidence of Second Primary Head and Neck Cancer: A SEER Database Analysis. International Journal of Radiation Oncology*Biology*Physics 71:1, 192-198
CrossRef305
Rafał Suwiński, Magdalena Bańkowska-Woźniak, Wojciech Majewski, Adam Idasiak, Adam Maciejewski, Ewa Ziółkowska, Wiesława Windorbska, Krzysztof Składowski, Leszek Miszczyk, Bogusław Maciejewski. (2008) Randomized clinical trial on 7-days-a-week postoperative radiotherapy for high-risk squamous cell head and neck cancer. Radiotherapy and Oncology 87:2, 155-163
CrossRef306
Athanassios Argiris, Michalis V Karamouzis, David Raben, Robert L Ferris. (2008) Head and neck cancer. The Lancet 371:9625, 1695-1709
CrossRef307
Jacques Bernier. (2008) A multidisciplinary approach to squamous cell carcinomas of the head and neck: an update. Current Opinion in Oncology 20:3, 249-255
CrossRef308
F. Waldfahrer, H. Iro, R. Fietkau, M. Wittlinger. (2008) Kopf-Hals-Karzinome. best practice onkologie 3:2, 4-14
CrossRef309
Chien-Yu Lin, Li-Yu Lee, Shiang-Fu Huang, Chung-Jan Kang, Kang-Hsing Fan, Hung-Ming Wang, Eric Yen-Chao Chen, I.-How Chen, Chun-Ta Liao, Ann-Joy Cheng, Joseph Tung-Chieh Chang. (2008) Treatment Outcome of Combined Modalities for Buccal Cancers: Unilateral or Bilateral Neck Radiation?. International Journal of Radiation Oncology*Biology*Physics 70:5, 1373-1381
CrossRef310
Aron Popovtzer, Avraham Eisbruch. (2008) Advances in radiation therapy of head and neck cancer. Expert Review of Anticancer Therapy 8:4, 633-644
CrossRef311
Carolyn Levis, Stuart Archibald. (2008) Clinical Research in Head and Neck Reconstruction. Clinics in Plastic Surgery 35:2, 227-237
CrossRef312
Alfred J Fleming, Michael E Johansen. (2008) The clinicianʼs expectations from the use of positron emission tomography/computed tomography scanning in untreated and treated head and neck cancer patients. Current Opinion in Otolaryngology & Head and Neck Surgery 16:2, 127-134
CrossRef313
S. Marur, A. A. Forastiere. (2008) Head and Neck Cancer: Changing Epidemiology, Diagnosis, and Treatment. Mayo Clinic Proceedings 83:4, 489-501
CrossRef314
Ambrose Chung-Wai Ho, Wai-Kuen Ho, Paul Kin-Yip Lam, Anthony Po-Wing Yuen, William Ignace Wei. (2008) Thyroid dysfunction in laryngectomees—10 years after treatment. Head & Neck 30:3, 336-340
CrossRef315
Clemens Klug, Dominik Berzaczy, Martin Voracek, Werner Millesi. (2008) Preoperative chemoradiotherapy in the management of oral cancer: A review. Journal of Cranio-Maxillofacial Surgery 36:2, 75-88
CrossRef316
Athanassios Argiris, Michalis V. Karamouzis, Jonas T. Johnson, Dwight E. Heron, Eugene Myers, David Eibling, Elmer Cano, Susan Urba, Jack Gluckman, Jennifer R. Grandis, Yun Wang, Sanjiv S. Agarwala. (2008) Long-Term Results of a Phase III Randomized Trial of Postoperative Radiotherapy With or Without Carboplatin in Patients With High-Risk Head and Neck Cancer. The Laryngoscope 118:3, 444-449
CrossRef317
M. Saunders, A.M. Rojas, S. Dische. (2008) CHART Revisited: A Conservative Approach for Advanced Head and Neck Cancer. Clinical Oncology 20:2, 127-133
CrossRef318
Dirk Rades, Monika Stoehr, Nadja Kazic, Samer G. Hakim, Annette Walz, Steven E. Schild, Juergen Dunst. (2008) Locally Advanced Stage IV Squamous Cell Carcinoma of the Head and Neck: Impact of Pre-Radiotherapy Hemoglobin Level and Interruptions During Radiotherapy. International Journal of Radiation Oncology*Biology*Physics 70:4, 1108-1114
CrossRef319
Kolja Freier, Michael Engel, Katja Lindel, Christa Flechtenmacher, Joachim Mühling, Stefan Hassfeld, Christof Hofele. (2008) Neoadjuvant concurrent radiochemotherapy followed by surgery in advanced oral squamous cell carcinoma (OSCC): A retrospective analysis of 207 patients. Oral Oncology 44:2, 116-123
CrossRef320
Dirk Rades, Fabian Fehlauer, Mashid Sheikh-Sarraf, Nadja Kazic, Hiba Basic, Robert Poorter, Samer G. Hakim, Steven E. Schild, Juergen Dunst. (2008) Toxicity of two cisplatin-based radiochemotherapy regimens for the treatment of patients with stage III/IV head and neck cancer. Head & Neck 30:2, 235-241
CrossRef321
Mauro Palazzi, Stefano Tomatis, Ester Orlandi, Marco Guzzo, Claudia Sangalli, Paolo Potepan, Simona Fantini, Cristiana Bergamini, Cecilia Gavazzi, Lisa Licitra, Gabriele Scaramellini, Giulio Cantu', Patrizia Olmi. (2008) Effects of Treatment Intensification on Acute Local Toxicity During Radiotherapy for Head and Neck Cancer: Prospective Observational Study Validating CTCAE, Version 3.0, Scoring System. International Journal of Radiation Oncology*Biology*Physics 70:2, 330-337
CrossRef322
Amir Lavaf, Eric M. Genden, Jamie A. Cesaretti, Stuart Packer, Johnny Kao. (2008) Adjuvant radiotherapy improves overall survival for patients with lymph node-positive head and neck squamous cell carcinoma. Cancer 112:3, 535-543
CrossRef323
Joshua D. Epstein, Tara K. Knight, Joel B. Epstein, Mark A. Bride, Michael B. Nichol. (2008) Cost of care for early- and late-stage oral and pharyngeal cancer in the California Medicaid population. Head & Neck 30:2, 178-186
CrossRef324
Stephanie A. Shintani, Robert L. Foote, Val J. Lowe, Paul D. Brown, Yolanda I. Garces, Jan L. Kasperbauer. (2008) Utility of PET/CT Imaging Performed Early After Surgical Resection in the Adjuvant Treatment Planning for Head and Neck Cancer. International Journal of Radiation Oncology*Biology*Physics 70:2, 322-329
CrossRef325
Sven Saussez, Francois Lorfevre, Thomas Lequeux, Guy Laurent, Gilbert Chantrain, Francoise Vertongen, Gérard Toubeau, Christine Decaestecker, Robert Kiss. (2008) The determination of the levels of circulating galectin-1 and -3 in HNSCC patients could be used to monitor tumor progression and/or responses to therapy. Oral Oncology 44:1, 86-93
CrossRef326
Edouard Soriano, Claire Faure, Sylvie Lantuejoul, Emile Reyt, Michel Bolla, Elisabeth Brambilla, Christian A. Righini. (2008) Course and prognosis of basaloid squamous cell carcinoma of the head and neck: A case–control study of 62 patients. European Journal of Cancer 44:2, 244-250
CrossRef327
Gabriela Buck, Pia Huguenin, Sandro J. Stoeckli. (2008) Efficacy of neck treatment in patients with head and neck squamous cell carcinoma. Head & Neck 30:1, 50-57
CrossRef328
Adam Idasiak, Barbara Masłyk, Sławomir Blamek, Rafał Suwiński. (2008) Ocena ryzyka przerzutów odległych u chorych na raka krtani napromienianych pooperacyjnie. Otolaryngologia Polska 62:2, 149-157
CrossRef329
R. Mazeron, J. Bourhis. (2008) Carcinomes des voies aérodigestives supérieures: nouvelles approches en radiothérapie. Oncologie 10:1, 8-15
CrossRef330
J.M. Prades, A.P. Timoshenko, Th. Schmitt, M.P. Delolme, M. Francoz, C. Martin, L. Saban-roche, Ch. Martin. (2008) Planned neck dissection before combined chemoradiation for pyriform sinus carcinoma. Acta Oto-laryngologica 128:3, 324-328
CrossRef331
Edwin P.M. Jansen, Henk Boot, Mark P. Saunders, Tom D.L. Crosby, Ria Dubbelman, Harry Bartelink, Marcel Verheij, Annemieke Cats. (2007) A Phase I–II Study of Postoperative Capecitabine-Based Chemoradiotherapy in Gastric Cancer. International Journal of Radiation Oncology*Biology*Physics 69:5, 1424-1428
CrossRef332
Jayakar V. Nayak, Rohan R. Walvekar, Regiane S. Andrade, Nicole Daamen, Stephen Y. Lai, Athanassios Argiris, Ryan P. Smith, Dwight E. Heron, Robert L. Ferris, Jonas T. Johnson, Barton F. Branstetter. (2007) Deferring Planned Neck Dissection Following Chemoradiation for Stage IV Head and Neck Cancer: The Utility of PET-CT. The Laryngoscope 117:12, 2129-2134
CrossRef333
Amy Law, Thomas Kennedy, Phillip Pellitteri, Craig Wood, Douglas Christie, Omar Yumen. (2007) Efficacy and Safety of Subcutaneous Amifostine in Minimizing Radiation-Induced Toxicities in Patients Receiving Combined-Modality Treatment for Squamous Cell Carcinoma of the Head and Neck. International Journal of Radiation Oncology*Biology*Physics 69:5, 1361-1368
CrossRef334
Tomasz Rutkowski, Rafal Suwinski, Adam Idasiak. (2007) The Prognostic Value of Hemoglobin Concentration in Postoperative Radiotherapy of 835 Patients With Laryngeal Cancer. International Journal of Radiation Oncology*Biology*Physics 69:4, 1018-1023
CrossRef335
Jai Prakash Agarwal, Ashwini Budrukkar, Sarbani Ghosh Laskar. (2007) Unplanned Interruptions: Unresolved Issues: In Regard to Bese et al. (Int J Radiat Oncol Biol Phys 2007;68:654–661). International Journal of Radiation Oncology*Biology*Physics 69:4, 1335-1336
CrossRef336
Matthew C. Biagioli, Mark Harvey, Eloy Roman, Luis E. Raez, Aaron H. Wolfson, Subhakar Mutyala, Hyo S. Han, Arnold Markoe. (2007) Intensity-Modulated Radiotherapy With Concurrent Chemotherapy for Previously Irradiated, Recurrent Head and Neck Cancer. International Journal of Radiation Oncology*Biology*Physics 69:4, 1067-1073
CrossRef337
Miriam S. Teixeira, Olga Camacho-Vanegas, Yolanda Fernandez, Goutham Narla, Analisa DiFeo, Bryant Lee, Tamara Kalir, Scott L. Friedman, Nicolas F. Schlecht, Eric M. Genden, Mark Urken, Margaret Brandwein-Gensler, John A. Martignetti. (2007) KLF6 allelic loss is associated with tumor recurrence and markedly decreased survival in head and neck squamous cell carcinoma. International Journal of Cancer 121:9, 1976-1983
CrossRef338
Posner, Marshall R., Hershock, Diane M., Blajman, Cesar R., Mickiewicz, Elizabeth, Winquist, Eric, Gorbounova, Vera, Tjulandin, Sergei, Shin, Dong M., Cullen, Kevin, Ervin, Thomas J., Murphy, Barbara A., Raez, Luis E., Cohen, Roger B., Spaulding, Monica, Tishler, Roy B., Roth, Berta, Viroglio, Rosana del Carmen, Venkatesan, Varagur, Romanov, Ilya, Agarwala, Sanjiv, Harter, K. William, Dugan, Matthew, Cmelak, Anthony, Markoe, Arnold M., Read, Paul W., Steinbrenner, Lynn, Colevas, A. Dimitrios, Norris, Charles M. Jr., Haddad, Robert I., . (2007) Cisplatin and Fluorouracil Alone or with Docetaxel in Head and Neck Cancer. New England Journal of Medicine 357:17, 1705-1715
Full Text339
Richard Oliver, Jan E Clarkson, David Conway, Anne-Marie Glenny, Michaelina Macluskey, Sue Pavitt, Philip Sloan, The CSROC Expert Panel, Helen V Worthington, Richard Oliver. 2007. Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment. .
CrossRef340
Tanguy Y. Seiwert, Everett E. Vokes. 2007. Head and Neck Cancer. .
CrossRef341
David J. Adelstein. (2007) Concurrent Chemoradiotherapy in the Management of Squamous Cell Cancer of the Oropharynx: Current Standards and Future Directions. International Journal of Radiation Oncology*Biology*Physics 69:2, S37-S39
CrossRef342
Kaisa Erjala, Na Zhang, Maria Sundvall, Jarmo Kulmala, Klaus Elenius, Reidar Grénman. (2007) Concomitant chemoirradiation with vinorelbine and gefitinib induces additive effect in head and neck squamous cell carcinoma cell lines in vitro. Radiotherapy and Oncology 85:1, 138-145
CrossRef343
Renzo Corvò. (2007) Evidence-based radiation oncology in head and neck squamous cell carcinoma. Radiotherapy and Oncology 85:1, 156-170
CrossRef344
E P M Jansen, H Boot, R Dubbelman, H Bartelink, A Cats, M Verheij. (2007) Postoperative chemoradiotherapy in gastric cancer – a phase I/II dose-finding study of radiotherapy with dose escalation of cisplatin and capecitabine chemotherapy. British Journal of Cancer 97:6, 712-716
CrossRef345
George H. Yoo, Vivian R. Tran, Lori A. Lemonnier, Waleed H. Ezzat, Geetha Subramanian, Marie P. Piechocki, John F. Ensley, Fulvio Lonardo, Harold Kim, Ho-Sheng Lin. (2007) BMS-275183–induced gene expression patterns in head and neck carcinoma. American Journal of Otolaryngology 28:5, 309-315
CrossRef346
Xavier León, Montserrat López, Zenaida Piñeiro, Johannes A. Langendijk, Charles R. Leemans, Miquel Quer. (2007) External validation of a risk group defined by recursive partitioning analysis in patients with head and neck carcinoma treated with surgery and postoperative radiotherapy. Head & Neck 29:9, 815-821
CrossRef347
Sven Saussez, Isabelle Camby, Gerard Toubeau, Robert Kiss. (2007) Galectins as modulators of tumor progression in head and neck squamous cell carcinomas. Head & Neck 29:9, 874-884
CrossRef348
Volker Budach. (2007) Chemo-enhanced radiotherapy in squamous cell carcinoma – Is there evidence for different regimes?. European Journal of Cancer Supplements 5:5, 432-433
CrossRef349
Mohit Kasibhatla, John P. Kirkpatrick, David M. Brizel. (2007) How Much Radiation is the Chemotherapy Worth in Advanced Head and Neck Cancer?. International Journal of Radiation Oncology*Biology*Physics 68:5, 1491-1495
CrossRef350
Hiroyuki Daiko, Ryuichi Hayashi, Masahisa Saikawa, Minoru Sakuraba, Mitsuo Yamazaki, Masakazu Miyazaki, Toru Ugumori, Masahiro Asai, Waichiro Oyama, Satoshi Ebihara. (2007) Surgical management of carcinoma of the cervical esophagus. Journal of Surgical Oncology 96:2, 166-172
CrossRef351
Michael J. Veness, Sandro Porceddu, Carsten E. Palme, Gary J. Morgan. (2007) Cutaneous head and neck squamous cell carcinoma metastatic to parotid and cervical lymph nodes. Head & Neck 29:7, 621-631
CrossRef352
Dirk Rades, Fabian Fehlauer, Junes Wroblesky, Dirk Albers, Steven E. Schild, Rainer Schmidt. (2007) Prognostic factors in head-and-neck cancer patients treated with surgery followed by intensity-modulated radiotherapy (IMRT), 3D-conformal radiotherapy, or conventional radiotherapy. Oral Oncology 43:6, 535-543
CrossRef353
Fernando C. Maluf, William N. William,, Otelo Rigato, Antonio D. Menon, Orlando Parise,, Marcos F. L. Docema. (2007) Necrotizing fasciitis as a late complication of multimodal treatment for locally advanced head and neck cancer: A case report. Head & Neck 29:7, 700-704
CrossRef354
D. Strumberg, A. Sendler, I.A. Adamietz. (2007) Carcinoma of unknown primary (CUP-Syndrom). Der Onkologe 13:7, 645-654
CrossRef355
D. Kademani. (2007) Oral Cancer. Mayo Clinic Proceedings 82:7, 878-887
CrossRef356
Kevin J. Cullen, Zejia Yang, Lisa Schumaker, Zhongmin Guo. (2007) Mitochondria as a critical target of the chemotheraputic agent cisplatin in head and neck cancer. Journal of Bioenergetics and Biomembranes 39:1, 43-50
CrossRef357
Merav A. Ben-David, Maximiliano Diamante, Jeffrey D. Radawski, Karen A. Vineberg, Cynthia Stroup, Carol-Anne Murdoch-Kinch, Samuel R. Zwetchkenbaum, Avraham Eisbruch. (2007) Lack of Osteoradionecrosis of the Mandible After Intensity-Modulated Radiotherapy for Head and Neck Cancer: Likely Contributions of Both Dental Care and Improved Dose Distributions. International Journal of Radiation Oncology*Biology*Physics 68:2, 396-402
CrossRef358
Martin C. Jäckel, Alexios Martin, Wolfgang Steiner. (2007) Twenty-five years experience with laser surgery for head and neck tumors. European Archives of Oto-Rhino-Laryngology 264:6, 577-585
CrossRef359
Anja Jonkman, Johannes H.A.M. Kaanders, Chris H.J. Terhaard, Frank J.P. Hoebers, Piet L.A. van den Ende, Oda B. Wijers, Lia C.G. Verhoef, Martin A. de Jong, C. René Leemans, Johannes A. Langendijk. (2007) Multicenter Validation of Recursive Partitioning Analysis Classification for Patients With Squamous Cell Head and Neck Carcinoma Treated With Surgery and Postoperative Radiotherapy. International Journal of Radiation Oncology*Biology*Physics 68:1, 119-125
CrossRef360
Johannes A Langendijk, Jean Bourhis. (2007) Reirradiation in squamous cell head and neck cancer: recent developments and future directions. Current Opinion in Oncology 19:3, 202-209
CrossRef361
Joel B. Epstein, Jennifer L. Beaumont, Clement K. Gwede, Barbara Murphy, Adam S. Garden, Ruby Meredith, Quynh-Thu Le, David Brizel, John Isitt, David Cella. (2007) Longitudinal evaluation of the oral mucositis weekly questionnaire-head and neck cancer, a patient-reported outcomes questionnaire. Cancer 109:9, 1914-1922
CrossRef362
David Murdoch. (2007) Standard, and novel cytotoxic and molecular-targeted, therapies for HNSCC: an evidence-based review. Current Opinion in Oncology 19:3, 216-221
CrossRef363
Hwan Jung Yun, Jan Bogaerts, Ahmad Awada, Denis Lacombe. (2007) Clinical trial design limitations in head and neck squamous cell carcinomas. Current Opinion in Oncology 19:3, 210-215
CrossRef364
Jean Bourhis, Aurélie Le Maître, Bertrand Baujat, Hélène Audry, Jean-Pierre Pignon. (2007) Individual patientsʼ data meta-analyses in head and neck cancer. Current Opinion in Oncology 19:3, 188-194
CrossRef365
Roland Bugat, François Planchamp, Thierry Lesimple, Jean-Jacques Voigt, Stéphane Culine, Alain Lortholary, Yacine Merrouche, Gérard Ganem, Marie-Christine Kaminsky, Sylvie Négrier, Maurice Pérol, Karim Fizazi, Emmanuel Blot. (2007) Bulletin de synthèse de veille 2006. Oncologie 9:4, 313-316
CrossRef366
Jergin Chen, Lisa Pappas, John H. Moeller, Jim Rankin, Pramod K. Sharma, Brandon G. Bentz, L. Christine Fang, John K. Hayes, Dennis C. Shrieve, Ying J. Hitchcock. (2007) Treatment of oropharyngeal squamous cell carcinoma with external beam radiation combined with interstitial brachytherapy. Head & Neck 29:4, 362-369
CrossRef367
Min Yao, Kristi Chang, Gerry F. Funk, Heming Lu, Huaming Tan, Judith Wacha, Kenneth J. Dornfeld, John M. Buatti. (2007) The Failure Patterns of Oral Cavity Squamous Cell Carcinoma After Intensity-Modulated Radiotherapy—The University of Iowa Experience. International Journal of Radiation Oncology*Biology*Physics 67:5, 1332-1341
CrossRef368
Adam S Garden, Mark S Chambers. (2007) Head and neck radiation and mucositis. Current Opinion in Supportive and Palliative Care 1:1, 30-34
CrossRef369
Assuntina G Sacco, Douglas B Chepeha. (2007) Current status of transport-disc-distraction osteogenesis for mandibular reconstruction. The Lancet Oncology 8:4, 323-330
CrossRef370
Christopher D. Willey, Barbara A. Murphy, James L. Netterville, Brian B. Burkey, Yu Shyr, Bashar Shakhtour, Bonnie Kish, David Raben, Changhu Chen, John I. Song, Madeleine A. Kane, Anthony J. Cmelak. (2007) A Phase II Multi-institutional Trial of Chemoradiation Using Weekly Docetaxel and Erythropoietin for High-Risk Postoperative Head and Neck Cancer Patients. International Journal of Radiation Oncology*Biology*Physics 67:5, 1323-1331
CrossRef371
Joel B. Epstein, Ira R. Parker, Matthew S. Epstein, Anurag Gupta, Susan Kutis, Daniela M. Witkowski. (2007) A survey of National Cancer Institute-designated comprehensive cancer centers’ oral health supportive care practices and resources in the USA. Supportive Care in Cancer 15:4, 357-362
CrossRef372
Tanguy Y Seiwert, Joseph K Salama, Everett E Vokes. (2007) The chemoradiation paradigm in head and neck cancer. Nature Clinical Practice Oncology 4:3, 156-171
CrossRef373
John G Devlin, Corey J Langer. (2007) Combined modality treatment of laryngeal squamous cell carcinoma. Expert Review of Anticancer Therapy 7:3, 331-350
CrossRef374
Branko Zakotnik, Marjan Budihna, Lojze Smid, Erika Soba, Primoz Strojan, Igor Fajdiga, Miha Zargi, Irena Oblak, Hotimir Lesnicar. (2007) Patterns of failure in patients with locally advanced head and neck cancer treated postoperatively with irradiation or concomitant irradiation with Mitomycin C and Bleomycin. International Journal of Radiation Oncology*Biology*Physics 67:3, 685-690
CrossRef375
Par S Mehta, Louis B Harrison. (2007) Function and organ preservation in adult cancers of the head and neck. Expert Review of Anticancer Therapy 7:3, 361-371
CrossRef376
Mike Yao, Joel B. Epstein, Bijal J. Modi, Kristen B. Pytynia, Arno J. Mundt, Lawrence E. Feldman. (2007) Current surgical treatment of squamous cell carcinoma of the head and neck. Oral Oncology 43:3, 213-223
CrossRef377
Søren M Bentzen, Paul M Harari, Jacques Bernier. (2007) Exploitable mechanisms for combining drugs with radiation: concepts, achievements and future directions. Nature Clinical Practice Oncology 4:3, 172-180
CrossRef378
Robert L. Foote, Paul D. Brown, Yolanda I. Garces, Scott H. Okuno, Robert C. Miller, Scott E. Strome. (2007) Informed consent in advanced laryngeal cancer. Head & Neck 29:3, 230-235
CrossRef379
Richard L. Scher. (2007) Role of Nitric Oxide in the Development of Distant Metastasis From Squamous Cell Carcinoma. The Laryngoscope 117:2, 199-209
CrossRef380
Tim K. Blackburn, Syeda Bakhtawar, James S. Brown, Derek Lowe, E.D. Vaughan, Simon N. Rogers. (2007) A questionnaire survey of current UK practice for adjuvant radiotherapy following surgery for oral and oropharyngeal squamous cell carcinoma. Oral Oncology 43:2, 143-149
CrossRef381
Kang-Hsing Fan, Chen-Yu Lin, Chung-Jan Kang, Shiang-Fu Huang, Hung-Ming Wang, Eric Yen-Chao Chen, I.-How Chen, Chun-Ta Liao, Ann-Joy Cheng, Joseph Tung-Chieh Chang. (2007) Combined-modality treatment for advanced oral tongue squamous cell carcinoma. International Journal of Radiation Oncology*Biology*Physics 67:2, 453-461
CrossRef382
R. Fietkau, R.P. Mueller, H. Iro. (2007) Adjuvante Behandlung von Tumoren der Kopf-Hals-Region. Der Onkologe 13:2, 109-117
CrossRef383
Kunitoshi Yoshino, Takashi Fujii, Hirokazu Uemura, Homare Akahane, Tomoyuki Kurita, Motoyuki Suzuki, Nobuhiro Uwa. (2007) Strategies for Advanced Carcinoma of the Hypopharynx at OMCCCD. Nihon Kikan Shokudoka Gakkai Kaiho 58:2, 112-118
CrossRef384
Jonathan J. Beitler, Richard V. Smith, Randall P. Owen, Carl E. Silver, Madhu Mazumdar, Scott Wadler. (2007) Phase II clinical trial of parenteral hydroxyurea and hyperfractionated, accelerated external beam radiation therapy in patients with advanced squamous cell carcinoma of the head and neck: Toxicity and efficacy with continuous ribonucleoside reductase inhibition. Head & Neck 29:1, 18-25
CrossRef385
J. Bernier, D. Schneider. (2007) Cetuximab combined with radiotherapy: An alternative to chemoradiotherapy for patients with locally advanced squamous cell carcinomas of the head and neck?. European Journal of Cancer 43:1, 35-45
CrossRef386
X Zhang, JA Moche, D Farber, SE Strome. (2007) Vaccine-based approaches to squamous cell carcinoma of the head and neck. Oral Diseases 13:1, 17-22
CrossRef387
Eric Winquist, Tom Oliver, Ralph Gilbert, . (2007) Postoperative chemoradiotherapy for advanced squamous cell carcinoma of the head and neck: A systematic review with meta-analysis. Head & Neck 29:1, 38-46
CrossRef388
Hilda E. Stambuk, Sasan Karimi, Nancy Lee, Snehal G. Patel. (2007) Oral Cavity and Oropharynx Tumors. Radiologic Clinics of North America 45:1, 1-20
CrossRef389
Takahide Taguchi, Mamoru Tsukuda, Yasukazu Mikami, Hideki Matsuda, Choichi Horiuchi, Ken-ichi Satake, Yasuhiro Takahashi, Goshi Nishimura. (2007) Concurrent chemoradiotherapy for patients with squamous cell carcinoma of the hypopharynx. Toukeibu Gan 33:3, 309-313
CrossRef390
N. BHATIA, R.K. SHAH, M. VILLACORTA, R. McQUILLAN, D.J. ANNINO, E.E. REBEIZ. (2006) Effect of rehabilitation facility location on outcomes in head and neck surgical patients. European Journal of Cancer Care 15:5, 458-462
CrossRef391
Nasfat J. Shehadeh, John F. Ensley, Omer Kucuk, Carri Black, George H. Yoo, John Jacobs, Ho-Sheng Lin, Lance K. Heilbrun, Daryn Smith, Harold Kim. (2006) Benefit of postoperative chemoradiotherapy for patients with unknown primary squamous cell carcinoma of the head and neck. Head & Neck 28:12, 1090-1098
CrossRef392
Russell W. Hinerman, Christopher G. Morris, Robert J. Amdur, Christopher D. Lansford, John W. Werning, Douglas B. Villaret, William M. Mendenhall. (2006) Surgery and Postoperative Radiotherapy for Squamous Cell Carcinoma of the Larynx and Pharynx. American Journal of Clinical Oncology 29:6, 613-621
CrossRef393
C. Mariette, J.P. Triboulet. (2006) Which treatment for squamous cell carcinoma of the pharyngoesophageal junction?. Journal of Surgical Oncology 94:3, 175-177
CrossRef394
Robert Haddad, Lori Wirth, Marshall Posner. (2006) Emerging drugs for head and neck cancer. Expert Opinion on Emerging Drugs 11:3, 461-467
CrossRef395
Jacques Bernier. (2006) Head and neck oncology: what the past decade has taught us. Expert Review of Anticancer Therapy 6:9, 1133-1136
CrossRef396
DE Costea, O Tsinkalovsky, OK Vintermyr, AC Johannessen, IC Mackenzie. (2006) Cancer stem cells – new and potentially important targets for the therapy of oral squamous cell carcinoma. Oral Diseases 12:5, 443-454
CrossRef397
Chun-Ta Liao, Hung-Ming Wang, Shu-Hang Ng, Tzu-Chen Yen, Li-Yu Lee, Chuen Hsueh, Fu-Chan Wei, I-How Chen, Chung-Jan Kang, Shiang-Fu Huang, Joseph Tung-Chieh Chang. (2006) Good tumor control and survivals of squamous cell carcinoma of buccal mucosa treated with radical surgery with or without neck dissection in Taiwan. Oral Oncology 42:8, 800-809
CrossRef398
Igor Astsaturov, Roger B Cohen, Paul Harari. (2006) Targeting epidermal growth factor receptor signaling in the treatment of head and neck cancer. Expert Review of Anticancer Therapy 6:9, 1179-1193
CrossRef399
Stuart C. Winter, Ketan A. Shah, Cheng Han, Leticia Campo, Helen Turley, Russell Leek, Rogan J. Corbridge, Graham J. Cox, Adrian L. Harris. (2006) The relation between hypoxia-inducible factor (HIF)-1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer. Cancer 107:4, 757-766
CrossRef400
Frank J.P. Hoebers, Dick Pluim, Marcel Verheij, Alfons J.M. Balm, Harry Bartelink, Jan H.M. Schellens, Adrian C. Begg. (2006) Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT). International Journal of Cancer 119:4, 750-756
CrossRef401
Alexander D. Rapidis, Miltiades Trichas, Elias Stavrinidis, Alexandra Roupakia, Georgia Ioannidou, George Kritselis, Panaiyota Liossi, George Giannakouras, Emmanuel E. Douzinas, Ioannis Katsilieris. (2006) Induction chemotherapy followed by concurrent chemoradiation in advanced squamous cell carcinoma of the head and neck: Final results from a phase II study with docetaxel, cisplatin and 5-fluorouracil with a four-year follow-up. Oral Oncology 42:7, 675-684
CrossRef402
Chun-Ta Liao, Hung-Ming Wang, Ling-Ling Hsieh, Joseph Tung-Chieh Chang, Shu-Hang Ng, Chuen Hsueh, Li-Yu Lee, Chih Hung Lin, I-How Chen, Chung-Jan Kang, Shiang-Fu Huang, Tzu-Chen Yen. (2006) Higher distant failure in young age tongue cancer patients. Oral Oncology 42:7, 718-725
CrossRef403
Jonathan R. Clark, John de Almeida, Ralph Gilbert, Jonathan Irish, Dale Brown, Peter Neligan, Patrick J. Gullane. (2006) Primary and salvage (hypo)pharyngectomy: Analysis and outcome. Head & Neck 28:8, 671-677
CrossRef404
Kumar Prabhash, V R Pai, Purvish M Parikh, Ameesh Vora, Kumar Prabhash. 2006. Postoperative chemoradiation for head and neck cancers. .
CrossRef405
Sven Saussez, Diana-Raluca Cucu, Christine Decaestecker, Dominique Chevalier, Herbert Kaltner, Sabine André, Agnes Wacreniez, Gérard Toubeau, Isabelle Camby, Hans-Joachim Gabius, Robert Kiss. (2006) Galectin 7 (p53-Induced Gene 1): A New Prognostic Predictor of Recurrence and Survival in Stage IV Hypopharyngeal Cancer. Annals of Surgical Oncology 13:7, 999-1009
CrossRef406
David Chin, Glen M Boyle, Sandro Porceddu, David R Theile, Peter G Parsons, William B Coman. (2006) Head and neck cancer: past, present and future. Expert Review of Anticancer Therapy 6:7, 1111-1118
CrossRef407
Wendell G. Yarbrough, Robbert J. C. Slebos, Daniel Liebler. (2006) Proteomics: Clinical applications for head and neck squamous cell carcinoma. Head & Neck 28:6, 549-558
CrossRef408
C Onesto, J-M Hannoun-Lévi, E Chamorey, J-L Formento, A Ramaioli, G Pagès. (2006) Vascular endothelial growth factor-A and Poly(A) binding protein-interacting protein 2 expression in human head and neck carcinomas: correlation and prognostic significance. British Journal of Cancer 94:10, 1516-1523
CrossRef409
K C Soo, J Wee, E H Tan. (2006) Reply: Surgery vs chemoRT for locally advanced operable head and neck cancers. British Journal of Cancer 94:10, 1546-1547
CrossRef410
A. F. Kovács, K. Eberlein, A. Smolarz, S. Weidauer, S. Rohde. (2006) Organerhaltende Therapie bei inoperablen Patienten mit primären Mundhöhlen- und Oropharynxkarzinomen. Mund-, Kiefer- und Gesichtschirurgie 10:3, 168-177
CrossRef411
Jacques Bernier, Soeren M Bentzen. (2006) Radiotherapy for head and neck cancer: latest developments and future perspectives. Current Opinion in Oncology 18:3, 240-246
CrossRef412
S. Seeber, D. Strumberg. (2006) Metastasen mit unbekanntem Primärtumor (CUP). Der Urologe 45:5, 614-619
CrossRef413
Lisa Licitra, Paolo Bossi, Laura D Locati. (2006) A multidisciplinary approach to squamous cell carcinomas of the head and neck: what is new?. Current Opinion in Oncology 18:3, 253-257
CrossRef414
Robert I. Haddad, Marshall R. Posner, Paul M. Busse, Charles M. Norris, Laura A. Goguen, Lori J. Wirth, Russell Blinder, Jeffrey F. Krane, Roy B. Tishler. (2006) Chemoradiotherapy for Adenoid Cystic Carcinoma. American Journal of Clinical Oncology 29:2, 153-157
CrossRef415
Nicolien Kasperts, Ben J. Slotman, C. Rene Leemans, Remco de Bree, Patricia Doornaert, Johannes A. Langendijk. (2006) Results of postoperative reirradiation for recurrent or second primary head and neck carcinoma. Cancer 106:7, 1536-1547
CrossRef416
Adam S. Garden, Jan S. Lewin, Mark S. Chambers. (2006) How to reduce radiation-related toxicity in patients with cancer of the head and neck. Current Oncology Reports 8:2, 140-145
CrossRef417
D.L. Schwartz, A.S. Garden. (2006) Radiotherapy for Head and Neck Cancer. Hematology/Oncology Clinics of North America 20:2, 259-285
CrossRef418
Robert Haddad. (2006) Current and future directions in the treatment of squamous cell carcinoma of the head and neck: multidisciplinary symposium on head and neck cancer. Expert Opinion on Therapeutic Targets 10:2, 333-336
CrossRef419
Maie A.R. St John, Elliot Abemayor, David T.W. Wong. (2006) Recent new approaches to the treatment of head and neck cancer. Anti-Cancer Drugs 17:4, 365-375
CrossRef420
S Ghosh Laskar, J P Agarwal, C Srinivas, K A Dinshaw. (2006) Radiotherapeutic management of locally advanced head and neck cancer. Expert Review of Anticancer Therapy 6:3, 405-417
CrossRef421
Marco Merlano, Valentina Polla Mattiot. (2006) Future chemotherapy and radiotherapy options in head and neck cancer. Expert Review of Anticancer Therapy 6:3, 395-403
CrossRef422
William I. Wei, Alfio Ferlito, Alessandra Rinaldo, Christine G. Gourin, John Lowry, Wai Kuen Ho, C. René Leemans, Ashok R. Shaha, Carlos Suárez, Gary L. Clayman, K. Thomas Robbins, Patrick J. Bradley, Carl E. Silver. (2006) Management of the N0 neck—reference or preference. Oral Oncology 42:2, 115-122
CrossRef423
Ken-Ichiro Shimizu, Hiroyuki Inoue, Miki Saitoh, Naoki Ohtsuki, Haruhiko Ishida, Kunihiko Makino, Mutsuo Amatsu, Ken-Ichi Nibu. (2006) Distribution and impact of lymph node metastases in oropharyngeal cancer. Acta Oto-laryngologica 126:8, 872-877
CrossRef424
Nicholas W. Choong, Ezra E.W. Cohen. (2006) Epidermal growth factor receptor directed therapy in head and neck cancer. Critical Reviews in Oncology/Hematology 57:1, 25-43
CrossRef425
A.K. D'cruz, G.H. Pantvaidya, J.P. Agarwal, D.A. Chaukar, K.A. Pathak, M.S. Deshpande, P.S. Pai, P. Chaturvedi, K.A. Dinshaw. (2006) Split therapy: Planned neck dissection followed by definitive radiotherapy for a T1, T2 pharyngolaryngeal primary cancer with operable N2, N3 nodal metastases—A prospective study. Journal of Surgical Oncology 93:1, 56-61
CrossRef426
Kazuto MATSUURA, Shigeru SAIJO, Yukinori ASADA, Hitoshi NISHIKAWA, Hiromichi KIYAKAWA, Kiyoto SHIGA, Masaru TATEDA, Junkichi YOKOYAMA, Fumiaki YOSHIDA. (2006) RESULTS OF POST-OPERATIVE TREATMENT FOR PATHOLOGICAL LYMPH NODE POSITIVE SQUAMOUS CELL CARCINOMAS OF THE MOUTH, MESOPHARYNX AND HYPOPHARYNX. Toukeibu Gan 32:1, 61-67
CrossRef427
Toshiki TOMITA, Hiroyuki OZAWA, Takamasa TAGAWA, Koji SAKAMOTO, Kaoru OGAWA, Masato FUJII. (2006) EVIDENCE OF HEAD AND NECK SURGERY AND FUTURE STRATEGY FOR MULTI-INSTITUTIONAL STUDIES. Toukeibu Gan 32:3, 300-305
CrossRef428
George H. Yoo, Ho-Sheng Lin, Andrew J. Iskander, Marie P. Piechocki, Jeffery Oliver, Danny Kewson, Fulvio Lonardo, Michael A. Tainsky, Hyeong-Reh Kim, Harold Kim, John F. Ensley. (2005) Docetaxel Associated Pathways in Cisplatin Resistant Head and Neck Squamous Cell Carcinoma: A Pilot Study. The Laryngoscope 115:11, 1938-1946
CrossRef429
Randal S. Weber, Merrill S. Kies, David I. Rosenthal. (2005) Postoperative treatment intensification for improving outcome in the high-risk patient: An evolutionary process. Head & Neck 27:10, 841-842
CrossRef430
Bin S. Teh, Arnold C. Paulino, E Brian Butler. (2005) Reirradiation in the Era of IMRT. American Journal of Clinical Oncology 28:5, 472-473
CrossRef431
Steven J Frank, KS Clifford Chao, David L Schwartz, Randal S Weber, Smith Apisarnthanarax, Homer A Macapinlac. (2005) Technology Insight: PET and PET/CT in head and neck tumor staging and radiation therapy planning. Nature Clinical Practice Oncology 2:10, 526-533
CrossRef432
Johannes A. Langendijk, Ben J. Slotman, Isaac van der Waal, P. Doornaert, Johannes Berkof, Charles R. Leemans. (2005) Risk-group definition by recursive partitioning analysis of patients with squamous cell head and neck carcinoma treated with surgery and postoperative radiotherapy. Cancer 104:7, 1408-1417
CrossRef433
Jacques Bernier, Jay S. Cooper, T. F. Pajak, M. van Glabbeke, J. Bourhis, Arlene Forastiere, Esat Mahmut Ozsahin, John R. Jacobs, J. Jassem, Kie-Kian Ang, J. L. Lefèbvre. (2005) Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501). Head & Neck 27:10, 843-850
CrossRef434
K-C Soo, E-H Tan, J Wee, D Lim, B-C Tai, M-L Khoo, C Goh, S-S Leong, T Tan, K-W Fong, P Lu, A See, D Machin. (2005) Surgery and adjuvant radiotherapy vs concurrent chemoradiotherapy in stage III/IV nonmetastatic squamous cell head and neck cancer: a randomised comparison. British Journal of Cancer 93:3, 279-286
CrossRef435
Samir Narayan. (2005) The use of intensity-modulated radiation therapy in the treatment of oropharyngeal carcinoma. Current Opinion in Otolaryngology & Head and Neck Surgery 13:4, 226-232
CrossRef436
Hilkka A. Jääskelä-Saari, Reidar Grénman, Hans A. Ramsay, Jussi Tarkkanen, Timo Paavonen, Kalevi J.A. Kairemo. (2005) Indium-111-Bleomycin Complex in Squamous Cell Cancer Xenograft Tumors of Nude Mice. Cancer Biotherapy & Radiopharmaceuticals 20:4, 426-435
CrossRef437
Ketayun Ardeshir Dinshaw, Jai Prakash Agarwal, Sarbani Ghosh Laskar, Tejpal Gupta, Shyam Kishore Shrivastava, Anil D. Cruz. (2005) Head and neck squamous cell carcinoma: The role of post-operative adjuvant radiotherapy. Journal of Surgical Oncology 91:1, 48-55
CrossRef438
C. Simon. (2005) Magnetisches Drug-Targeting. HNO 53:7, 600-601
CrossRef439
Wei Lin, Xioayu Zhang, Zhaorong Chen, Nancy Borson, Steve Voss, Schuyler Sanderson, Linda Murphy, Peter Wettstein, Scott E. Strome. (2005) Development and Immunophenotyping of Squamous Cell Carcinoma Xenografts: Tools for Translational Immunology. The Laryngoscope 115:7, 1154-1162
CrossRef440
Marion Couch. (2005) What’s New in Otolaryngology—Head and Neck Surgery. Journal of the American College of Surgeons 201:1, 101-109
CrossRef441
Brian A. Moore, F. Christopher Holsinger, Eduardo M. Diaz, Randal S. Weber. (2005) Organ-Preservation Laryngeal Surgery in the Era of Chemoradiation. Current Problems in Cancer 29:4, 169-179
CrossRef442
Bijal J Modi, Brian Knab, Lawrence E Feldman, Arno J Mundt, Mike Yao, Kristen B Pytynia, Joel Epstein. (2005) Review of current treatment practices for carcinoma of the head and neck. Expert Opinion on Pharmacotherapy 6:7, 1143-1155
CrossRef443
Jordi Giralt, Jacques Bernier. (2005) Postoperative radiotherapy with simultaneous chemotherapy in high-risk squamous cell carcinoma of the head and neck: a novel standard that opens new questions. Clinical and Translational Oncology 7:5, 181-182
CrossRef444
Victoria Reyes López, Begoña Navalpotro Yagüe. (2005) Adjuvant treatment of locally-advanced head and neck tumours. Clinical and Translational Oncology 7:5, 183-188
CrossRef445
David I Rosenthal, Angel I Blanco. (2005) Head and neck squamous cell carcinoma: optimizing the therapeutic index. Expert Review of Anticancer Therapy 5:3, 501-514
CrossRef446
J. A. Werner. (2005) Sentinel-Lymphonodektomie als Stagingverfahren. HNO 53:6, 511-514
CrossRef447
William M. Mendenhall, Christopher G. Morris, Robert J. Amdur, John W. Werning, Douglas B. Villaret. (2005) Retromolar trigone squamous cell carcinoma treated with radiotherapy alone or combined with surgery. Cancer 103:11, 2320-2325
CrossRef448
A.L. Creak, K. Harrington, C. Nutting. (2005) Treatment of recurrent head and neck cancer: re-irradiation or chemotherapy?. Clinical Oncology 17:3, 138-147
CrossRef449
Ronaldo Bova, Raymond Goh, Michael Poulson, William B. Coman. (2005) Total Pharyngolaryngectomy for Squamous Cell Carcinoma of the Hypopharynx: A Review. The Laryngoscope 115:5, 864-869
CrossRef450
T Y Seiwert, E E W Cohen. (2005) State-of-the-art management of locally advanced head and neck cancer. British Journal of Cancer 92:8, 1341-1348
CrossRef451
Ozden Altundag, Kadri Altundag, Paolo Morandi, Emer Hanrahan. (2005) Cisplatin as a radiosensitizer in the treatment of locally advanced head and neck cancer. Oral Oncology 41:4, 435
CrossRef452
Joseph K. Salama, Daniel J. Haraf, Kerstin Stenson, Michael T. Milano, Mary Ellyn Witt, Everett E. Yokes. (2005) Phase I Study of Concomitant Chemoradiotherapy with Irinotecan, 5-FU., and Hydroxyurea for Patients with Advanced and/or Recurrent Head and Neck Cancer. The Cancer Journal 11:2, 140-146
CrossRef453
G. Dyckhoff, C. Herold-Mende. (2005) Anti-Tumor-Impfung bei HNO-Tumoren. HNO 53:3, 209-212
CrossRef454
Terry A. Day, Ricardo A. Beas, Rodney J. Schlosser, Bradford A. Woodworth, Julio Barredo, Anand K. Sharma, M. Boyd Gillespie. (2005) Management of paranasal sinus malignancy. Current Treatment Options in Oncology 6:1, 3-18
CrossRef455
Barbara A Murphy. (2005) Topoisomerases in the treatment of metastatic or recurrent squamous carcinoma of the head and neck. Expert Opinion on Pharmacotherapy 6:1, 85-92
CrossRef456
K HU, L HARRISON. (2005) Point. Brachytherapy 4:1, 1-4
CrossRef457
Garfunkel, Adi A., . (2004) Oral Mucositis — The Search for a Solution. New England Journal of Medicine 351:25, 2649-2651
Full Text458
Jonathan A. Ship, Ken Hu. (2004) Radiotherapy-induced salivary dysfunction. Seminars in Oncology 31, 29-36
CrossRef459
Shujiro B. Minami, Su-Hua Sha, Jochen Schacht. (2004) Antioxidant protection in a new animal model of cisplatin-induced ototoxicity. Hearing Research 198:1-2, 137-143
CrossRef460
P. L. Zorat, A. Paccagnella, G. Cavaniglia, L. Loreggian, A. Gava, C. A. Mione, F. Boldrin, C. Marchiori, F. Lunghi, A. Fede, A. Bordin, M. C. Da Mosto, V. C. Sileni, A. Orlando, A. Jirillo, L. Tomio, G. L. Pappagallo, M. G. Ghi. (2004) Randomized Phase III Trial of Neoadjuvant Chemotherapy in Head and Neck Cancer: 10-Year Follow-Up. JNCI Journal of the National Cancer Institute 96:22, 1714-1717
CrossRef461
Russell W. Hinerman, William M. Mendenhall, Christopher G. Morris, Robert J. Amdur, John W. Werning, Douglas B. Villaret. (2004) Postoperative irradiation for squamous cell carcinoma of the oral cavity: 35-year experience. Head & Neck 26:11, 984-994
CrossRef462
Sue S Yom, David I Rosenthal. (2004) Does concurrent postoperative radiotherapy and chemotherapy in head and neck cancer improve patient outcome?. Nature Clinical Practice Oncology 1:1, 14-15
CrossRef463
Mangesh Thorat. (2004) Optimum cancer care—an unaffordable goal?. The Lancet Oncology 5:9, 530
CrossRef464
(2004) Treatment of Advanced Head and Neck Cancer. New England Journal of Medicine 351:8, 829-831
Full Text465
(2004) Oncology: Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. British Dental Journal 197:3, 137-137
CrossRef466
Cooper, Jay S., Pajak, Thomas F., Forastiere, Arlene A., Jacobs, John, Campbell, Bruce H., Saxman, Scott B., Kish, Julie A., Kim, Harold E., Cmelak, Anthony J., Rotman, Marvin, Machtay, Mitchell, Ensley, John F., Chao, K.S. Clifford, Schultz, Christopher J., Lee, Nancy, Fu, Karen K., . (2004) Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck. New England Journal of Medicine 350:19, 1937-1944
Full Text467
Saunders, Michele I., Rojas, Ana M., . (2004) Management of Cancer of the Head and Neck — A Cocktail with Your PORT?. New England Journal of Medicine 350:19, 1997-1999
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