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Interactive Medical Case

Graham T. McMahon, M.D., M.M.Sc., Editor, Joel T. Katz, M.D., Associate Editor, Bruce D. Levy, M.D., Associate Editor, Joseph Loscalzo, M.D., Ph.D., Associate Editor

A Startling Decline

Anand Vaidya, M.D., M.M.Sc., Brigid M. Dolan, M.D., Brian L. Edlow, M.D., Mikael L. Rinne, M.D., Ph.D., and Scott M. McGinnis, M.D., Ph.D.

N Engl J Med 2012; 366:e11February 9, 2012

Case

An 89-year-old man presented with changes in cognition and personality. Six months earlier, he began to require help managing his finances and operating his computer. His family observed that he had a poor memory for recent events and found it difficult to express himself. During the next few months, he became increasingly irritable and began to engage in some unusual behaviors, . . .

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About Interactive Medical Cases

Each interactive case presents an evolving patient history and a series of questions and exercises designed to test your diagnostic and therapeutic skills. You will receive immediate feedback on your answers and treatment choices, along with the opportunity to compare your final score with those of your peers. Video, animation, and interactive content allow you to learn more about mechanisms, diagnostic tests, and treatments.

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Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.