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Hypokalemia

Adam Nosworthy, M.B., B.Ch.

N Engl J Med 2003; 349:2116November 27, 2003

Article

A 42-year-old man was hospitalized because he had had confusion, weakness, and lethargy for approximately a week. Hypertension had recently been diagnosed, and the patient had begun therapy with a combination of amiloride and hydrochlorothiazide. His blood pressure was 170/100 mm Hg. An electrocardiogram showed sinus rhythm with prominent U waves (arrow) and a prolonged QT interval. The patient's serum sodium concentration was 118 mmol per liter, and his serum potassium concentration was 1.4 mmol per liter. Treatment with amiloride and hydrochlorothiazide was stopped. The patient received intravenous fluids, including supplemental potassium. Enalapril therapy was initiated for blood-pressure control. At discharge, his serum electrolyte levels and the electrocardiographic findings were normal.

Adam Nosworthy, M.B., B.Ch.
Johannesburg Hospital, Johannesburg 2000, South Africa

Citing Articles (2)

Citing Articles

  1. 1

    Jeroen Aerssens, Aimée DC Paulussen. (2005) Pharmacogenomics and acquired long QT syndrome. Pharmacogenomics 6:3, 259-270
    CrossRef

  2. 2

    Jones, Edward, . (2004) Hypokalemia. New England Journal of Medicine 350:11, 1156-1156
    Full Text

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